| High-Fat, High-Sugar Diet-Induced Subendothelial Matrix Stiffening is Mitigated by Exercise. Kohn JC, Azar J, Seta F, Reinhart-King CA (2018) Cardiovasc Eng Technol 9:84-93 | 2018 |
| Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis. Dear ML, Shilts J, Broadie K (2017) Sci Signal 10: | 2017 |
| The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain. Dohn MR, Kooker CG, Bastarache L, Jessen T, Rinaldi C, Varney S, Mazalouskas MD, Pan H, Oliver KH, Velez Edwards DR, Sutcliffe JS, Denny JC, Carneiro AMD (2017) J Neurosci 37:11271-11284 | 2017 |
| Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development. Mathew S, Palamuttam RJ, Mernaugh G, Ramalingam H, Lu Z, Zhang MZ, Ishibe S, Critchley DR, Fässler R, Pozzi A, Sanders CR, Carroll TJ, Zent R (2017) Development 144:4148-4158 | 2017 |
| Proteolytic processing of lysyl oxidase-like-2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV. López-Jiménez AJ, Basak T, Vanacore RM (2017) J Biol Chem 292:16970-16982 | 2017 |
| Building collagen IV smart scaffolds on the outside of cells. Brown KL, Cummings CF, Vanacore RM, Hudson BG (2017) Protein Sci 26:2151-2161 | 2017 |
| The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells. Jerrell RJ, Leih MJ, Parekh A (2017) Small GTPases :1-7 | 2017 |
| Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca-Regulated Genes. Stancill JS, Cartailler JP, Clayton HW, O'Connor JT, Dickerson MT, Dadi PK, Osipovich AB, Jacobson DA, Magnuson MA (2017) Diabetes 66:2175-2187 | 2017 |
| Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR (2017) Nature 545:243-247 | 2017 |
| The Vascular Wall: a Plastic Hub of Activity in Cardiovascular Homeostasis and Disease. Awgulewitsch CP, Trinh LT, Hatzopoulos AK (2017) Curr Cardiol Rep 19:51 | 2017 |
| The sulfilimine cross-link of collagen IV contributes to kidney tubular basement membrane stiffness. Bhave G, Colon S, Ferrell N (2017) Am J Physiol Renal Physiol 313:F596-F602 | 2017 |
| Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues. Fidler AL, Darris CE, Chetyrkin SV, Pedchenko VK, Boudko SP, Brown KL, Gray Jerome W, Hudson JK, Rokas A, Hudson BG (2017) Elife 6: | 2017 |
| High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation. Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schröder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J (2017) J Clin Invest 127:1944-1959 | 2017 |
| Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again! Wooten DJ, Quaranta V (2017) Biochim Biophys Acta 1867:167-175 | 2017 |
| Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. Hockman D, Burns AJ, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PDS, Lickert H, Tucker AS, Baker CVH (2017) Elife 6: | 2017 |
| Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue. Jovanović B, Sheng Q, Seitz RS, Lawrence KD, Morris SW, Thomas LR, Hout DR, Schweitzer BL, Guo Y, Pietenpol JA, Lehmann BD (2017) BMC Cancer 17:241 | 2017 |
| Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Minciacchi VR, Zijlstra A, Rubin MA, Di Vizio D (2017) Prostate Cancer Prostatic Dis 20:251-258 | 2017 |
| The susceptible HLA class II alleles and their presenting epitope(s) in Goodpasture's disease. Xie LJ, Cui Z, Chen FJ, Pei ZY, Hu SY, Gu QH, Jia XY, Zhu L, Zhou XJ, Zhang H, Liao YH, Lai LH, Hudson BG, Zhao MH (2017) Immunology 151:395-404 | 2017 |
| FSTL3 is increased in renal dysfunction. Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T (2017) Nephrol Dial Transplant 32:1637-1644 | 2017 |
| The innate immune response in fetal lung mesenchymal cells targets VEGFR2 expression and activity. Medal RM, Im AM, Yamamoto Y, Lakhdari O, Blackwell TS, Hoffman HM, Sahoo D, Prince LS (2017) Am J Physiol Lung Cell Mol Physiol 312:L861-L872 | 2017 |
| Zebrafish Developmental Models of Skeletal Diseases. Luderman LN, Unlu G, Knapik EW (2017) Curr Top Dev Biol 124:81-124 | 2017 |
| A mechanically coupled reaction-diffusion model that incorporates intra-tumoural heterogeneity to predictglioma growth. Hormuth DA, Weis JA, Barnes SL, Miga MI, Rericha EC, Quaranta V, Yankeelov TE (2017) J R Soc Interface 14: | 2017 |
| Both Drosophila matrix metalloproteinases have released and membrane-tethered forms but have different substrates. LaFever KS, Wang X, Page-McCaw P, Bhave G, Page-McCaw A (2017) Sci Rep 7:44560 | 2017 |
| An AcquiredGatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer. Hanker AB, Brewer MR, Sheehan JH, Koch JP, Sliwoski GR, Nagy R, Lanman R, Berger MF, Hyman DM, Solit DB, He J, Miller V, Cutler RE, Lalani AS, Cross D, Lovly CM, Meiler J, Arteaga CL (2017) Cancer Discov 7:575-585 | 2017 |
| A Randomized Phase II Neoadjuvant Study of Cisplatin, Paclitaxel With or Without Everolimus in Patients with Stage II/III Triple-Negative Breast Cancer (TNBC): Responses and Long-term Outcome Correlated with Increased Frequency of DNA Damage Response Gene Mutations, TNBC Subtype, AR Status, and Ki67. Jovanović B, Mayer IA, Mayer EL, Abramson VG, Bardia A, Sanders ME, Kuba MG, Estrada MV, Beeler JS, Shaver TM, Johnson KC, Sanchez V, Rosenbluth JM, Dillon PM, Forero-Torres A, Chang JC, Meszoely IM, Grau AM, Lehmann BD, Shyr Y, Sheng Q, Chen SC, Arteaga CL, Pietenpol JA (2017) Clin Cancer Res 23:4035-4045 | 2017 |
| Improving prediction of helix-helix packing in membrane proteins using predicted contact numbers as restraints. Li B, Mendenhall J, Nguyen ED, Weiner BE, Fischer AW, Meiler J (2017) Proteins 85:1212-1221 | 2017 |
| Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis. Bankaitis K, Borriello L, Cox T, Lynch C, Zijlstra A, Fingleton B, Gužvić M, Anderson R, Neman J (2017) Clin Exp Metastasis 34:203-213 | 2017 |
| Connecting imaging mass spectrometry and magnetic resonance imaging-based anatomical atlases for automated anatomical interpretation and differential analysis. Verbeeck N, Spraggins JM, Murphy MJM, Wang HD, Deutch AY, Caprioli RM, Van de Plas R (2017) Biochim Biophys Acta 1865:967-977 | 2017 |
| Mass Spectrometry Imaging Can Distinguish on a Proteomic Level Between Proliferative Nodules Within a Benign Congenital Nevus and Malignant Melanoma. Lazova R, Yang Z, El Habr C, Lim Y, Choate KA, Seeley EH, Caprioli RM, Yangqun L (2017) Am J Dermatopathol 39:689-695 | 2017 |
| Development of novel murine mammary imaging windows to examine wound healing effects on leukocyte trafficking in mammary tumors with intravital imaging. Sobolik T, Su YJ, Ashby W, Schaffer DK, Wells S, Wikswo JP, Zijlstra A, Richmond A (2016) Intravital 5:e1125562 | 2016 |
| High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling. Prentice BM, Chumbley CW, Caprioli RM (2016) J Mass Spectrom 51:665 | 2016 |
| The novel adipokine/hepatokine fetuin B in severe human and murine diabetic kidney disease. Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T (2017) Diabetes Metab 43:465-468 | 2017 |
| Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition. Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP (2017) Sci Rep 7:42604 | 2017 |
| Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moietyand: Implication in atherosclerosis. Lu J, Guo S, Xue X, Chen Q, Ge J, Zhuo Y, Zhong H, Chen B, Zhao M, Han W, Suzuki T, Zhu M, Xia L, Schneider C, Blackwell TS, Porter NA, Zheng L, Tsimikas S, Yin H (2017) J Biol Chem 292:5378-5391 | 2017 |
| Enhanced Spatially Resolved Proteomics Using On-Tissue Hydrogel-Mediated Protein Digestion. Rizzo DG, Prentice BM, Moore JL, Norris JL, Caprioli RM (2017) Anal Chem 89:2948-2955 | 2017 |
| Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors. Polosukhina D, Love HD, Correa H, Su Z, Dahlman KB, Pao W, Moses HL, Arteaga CL, Lovvorn HN, Zent R, Clark PE (2017) Mol Oncol 11:405-421 | 2017 |
| In vivo histone H1 migration from necrotic to viable tissue. Luhrs KA, Pink D, Schulte W, Zijlstra A, Lewis JD, Parseghian MH (2017) Oncotarget 8:16275-16292 | 2017 |
| The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo. Lavender N, Yang J, Chen SC, Sai J, Johnson CA, Owens P, Ayers GD, Richmond A (2017) BMC Cancer 17:88 | 2017 |
| Larger core size has superior technical and analytical accuracy in bladder tissue microarray. Eskaros AR, Egloff SA, Boyd KL, Richardson JE, Hyndman ME, Zijlstra A (2017) Lab Invest 97:335-342 | 2017 |
| Strategies to overcome therapeutic resistance in renal cell carcinoma. Siska PJ, Beckermann KE, Rathmell WK, Haake SM (2017) Urol Oncol 35:102-110 | 2017 |
| Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action. Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei YW, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM (2017) J Proteome Res 16:1364-1375 | 2017 |
| Bortezomib augments lymphocyte stimulatory cytokine signaling in the tumor microenvironment to sustain CD8+T cell antitumor function. Pellom ST, Dudimah DF, Thounaojam MC, Uzhachenko RV, Singhal A, Richmond A, Shanker A (2017) Oncotarget 8:8604-8621 | 2017 |
| Integrin alpha6 maintains the structural integrity of the kidney collecting system. Viquez OM, Yazlovitskaya EM, Tu T, Mernaugh G, Secades P, McKee KK, Georges-Labouesse E, De Arcangelis A, Quaranta V, Yurchenco P, Gewin LC, Sonnenberg A, Pozzi A, Zent R (2017) Matrix Biol 57-58:244-257 | 2017 |
| PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses. Sai J, Owens P, Novitskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A (2017) Clin Cancer Res 23:3371-3384 | 2017 |
| Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors. Cowen SD, Russell D, Dakin LA, Chen H, Larsen NA, Godin R, Throner S, Zheng X, Molina A, Wu J, Cheung T, Howard T, Garcia-Arenas R, Keen N, Pendleton CS, Pietenpol JA, Ferguson AD (2016) J Med Chem 59:11079-11097 | 2016 |
| MALDI Imaging Mass Spectrometry as a Lipidomic Approach to Heart Valve Research. Angel PM, Bayoumi AS, Hinton RB, Ru Su Y, Bichell D, Mayer JE, Scott Baldwin H, Caprioli RM (2016) J Heart Valve Dis 25:240-252 | 2016 |
| Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity. Udyavar AR, Wooten DJ, Hoeksema M, Bansal M, Califano A, Estrada L, Schnell S, Irish JM, Massion PP, Quaranta V (2017) Cancer Res 77:1063-1074 | 2017 |
| Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function. Lu Z, Mathew S, Chen J, Hadziselimovic A, Palamuttam R, Hudson BG, Fässler R, Pozzi A, Sanders CR, Zent R (2016) Elife 5: | 2016 |
| Life history linked to immune investment in developing amphibians. Woodhams DC, Bell SC, Bigler L, Caprioli RM, Chaurand P, Lam BA, Reinert LK, Stalder U, Vazquez VM, Schliep K, Hertz A, Rollins-Smith LA (2016) Conserv Physiol 4:cow025 | 2016 |
| Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP (2016) Nat Med 22:1502 | 2016 |
| Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis. Borza CM, Su Y, Tran TL, Yu L, Steyns N, Temple KJ, Skwark MJ, Meiler J, Lindsley CW, Hicks BR, Leitinger B, Zent R, Pozzi A (2017) Matrix Biol 57-58:258-271 | 2017 |
| Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling. Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS (2017) Am J Respir Crit Care Med 195:1010-1021 | 2017 |
| Micrometastatic Dormancy in Uveal Melanoma: A Comprehensive Review of the Evidence, Mechanisms, and Implications for Future Adjuvant Therapies. Nichols EE, Richmond A, Daniels AB (2017) Int Ophthalmol Clin 57:1-10 | 2017 |
| Basement membrane ultrastructure and component localization data from uterine tissues during early mouse pregnancy. Jones-Paris CR, Paria S, Berg T, Saus J, Bhave G, Paria BC, Hudson BG (2016) Data Brief 9:931-939 | 2016 |
| Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer. Arnold Egloff SA, Du L, Loomans HA, Starchenko A, Su PF, Ketova T, Knoll PB, Wang J, Haddad AQ, Fadare O, Cates JM, Lotan Y, Shyr Y, Clark PE, Zijlstra A (2017) Oncotarget 8:722-741 | 2017 |
| A Deep Hydrophobic Binding Cavity is the Main Interaction for Different YR Antagonists. Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG (2017) ChemMedChem 12:75-85 | 2017 |
| Renal cancer subtypes: Should we be lumping or splitting for therapeutic decision making? Haake SM, Rathmell WK (2017) Cancer 123:200-209 | 2017 |
| Evaluation of TSPO PET Ligands [F]VUIIS1009A and [F]VUIIS1009B: Tracers for Cancer Imaging. Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC (2017) Mol Imaging Biol 19:578-588 | 2017 |
| Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens aging. Nye-Wood MG, Spraggins JM, Caprioli RM, Schey KL, Donaldson PJ, Grey AC (2017) Exp Eye Res 154:70-78 | 2017 |
| MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions. Weck ML, Grega-Larson NE, Tyska MJ (2017) Curr Opin Cell Biol 44:68-78 | 2017 |
| TβRIII Expression in Human Breast Cancer Stroma and the Role of Soluble TβRIII in Breast Cancer Associated Fibroblasts. Jovanović B, Pickup MW, Chytil A, Gorska AE, Johnson KC, Moses HL, Owens P (2016) Cancers (Basel) 8: | 2016 |
| bcl::Cluster : A method for clustering biological molecules coupled with visualization in the Pymol Molecular Graphics System. Alexander N, Woetzel N, Meiler J (2011) IEEE Int Conf Comput Adv Bio Med Sci 2011:13-18 | 2011 |
| Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy. Wang X, Yao B, Wang Y, Fan X, Wang S, Niu A, Yang H, Fogo A, Zhang MZ, Harris RC (2017) Diabetes 66:494-504 | 2017 |
| Eph Receptor Tyrosine Kinases in Tumor Immunity. Shiuan E, Chen J (2016) Cancer Res 76:6452-6457 | 2016 |
| Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Meiler J, Crowe JE (2016) Proc Natl Acad Sci U S A 113:E6849-E6858 | 2016 |
| Genetic Evaluation and Testing of Patients and Families with Idiopathic Pulmonary Fibrosis. Kropski JA, Young LR, Cogan JD, Mitchell DB, Lancaster LH, Worrell JA, Markin C, Liu N, Mason WR, Fingerlin TE, Schwartz DA, Lawson WE, Blackwell TS, Phillips JA, Loyd JE (2017) Am J Respir Crit Care Med 195:1423-1428 | 2017 |
| LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer). Simonik EA, Cai Y, Kimmelshue KN, Brantley-Sieders DM, Loomans HA, Andl CD, Westlake GM, Youngblood VM, Chen J, Yarbrough WG, Brown BT, Nagarajan L, Brandt SJ (2016) PLoS One 11:e0164804 | 2016 |
| Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome. Young LR, Gulleman PM, Short CW, Tanjore H, Sherrill T, Qi A, McBride AP, Zaynagetdinov R, Benjamin JT, Lawson WE, Novitskiy SV, Blackwell TS (2016) JCI Insight 1:e88947 | 2016 |
| Progression of chronic kidney disease: too much cellular talk causes damage. Gewin L, Zent R, Pozzi A (2017) Kidney Int 91:552-560 | 2017 |
| Lysyl Oxidase-like-2 Cross-links Collagen IV of Glomerular Basement Membrane. Añazco C, López-Jiménez AJ, Rafi M, Vega-Montoto L, Zhang MZ, Hudson BG, Vanacore RM (2016) J Biol Chem 291:25999-26012 | 2016 |
| mTORC1 and mTORC2 in cancer and the tumor microenvironment. Kim LC, Cook RS, Chen J (2017) Oncogene 36:2191-2201 | 2017 |
| Improved prediction of trans-membrane spans in proteins using an Artificial Neural Network. Koehler J, Mueller R, Meiler J (2009) IEEE Symp Comput Intell Bioinforma Comput Biol Proc 2009:68-74 | 2009 |
| IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury. Zhang MZ, Wang X, Wang Y, Niu A, Wang S, Zou C, Harris RC (2017) Kidney Int 91:375-386 | 2017 |
| Developmental experience-dependent plasticity in the first synapse of the Drosophila olfactory circuit. Golovin RM, Broadie K (2016) J Neurophysiol 116:2730-2738 | 2016 |
| Trypsin and MALDI matrix pre-coated targets simplify sample preparation for mapping proteomic distributions within biological tissues by imaging mass spectrometry. Zubair F, Laibinis PE, Swisher WG, Yang J, Spraggins JM, Norris JL, Caprioli RM (2016) J Mass Spectrom 51:1168-1179 | 2016 |
| Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP (2016) Nat Med 22:1330-1334 | 2016 |
| Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex. Weck ML, Crawley SW, Stone CR, Tyska MJ (2016) Curr Biol 26:2717-2728 | 2016 |
| Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Events in a Single Laser Shot. Prentice BM, Chumbley CW, Caprioli RM (2017) J Am Soc Mass Spectrom 28:136-144 | 2017 |
| Structural basis for KCNE3 modulation of potassium recycling in epithelia. Kroncke BM, Van Horn WD, Smith J, Kang C, Welch RC, Song Y, Nannemann DP, Taylor KC, Sisco NJ, George AL, Meiler J, Vanoye CG, Sanders CR (2016) Sci Adv 2:e1501228 | 2016 |
| Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit during uterine reprogramming. Jones-Paris CR, Paria S, Berg T, Saus J, Bhave G, Paria BC, Hudson BG (2017) Matrix Biol 57-58:347-365 | 2017 |
| Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation. Borza DB (2017) Matrix Biol 57-58:299-310 | 2017 |
| Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions. Raval MH, Quintero OA, Weck ML, Unrath WC, Gallagher JW, Cui R, Kachar B, Tyska MJ, Yengo CM (2016) J Biol Chem 291:22781-22792 | 2016 |
| Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Quantification. Prentice BM, Chumbley CW, Hachey BC, Norris JL, Caprioli RM (2016) Anal Chem 88:9780-9788 | 2016 |
| A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD. Parsons ZD, Bland JM, Mullins EA, Eichman BF (2016) J Am Chem Soc 138:11485-8 | 2016 |
| The Need for Speed in Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry. Prentice BM, Caprioli RM (2016) Postdoc J 4:3-13 | 2016 |
| Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability. Kroncke BM, Duran AM, Mendenhall JL, Meiler J, Blume JD, Sanders CR (2016) Biochemistry 55:5002-9 | 2016 |
| Correction to Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues. Chumbley CW, Reyzer ML, Allen JL, Marriner GA, Via LE, Barry CE, Caprioli RM (2016) Anal Chem 88:8920 | 2016 |
| Patterning protein complexes on DNA nanostructures using a GFP nanobody. Sommese RF, Hariadi RF, Kim K, Liu M, Tyska MJ, Sivaramakrishnan S (2016) Protein Sci 25:2089-2094 | 2016 |
| Development of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer. Ludwik KA, Campbell JP, Li M, Li Y, Sandusky ZM, Pasic L, Sowder ME, Brenin DR, Pietenpol JA, O'Doherty GA, Lannigan DA (2016) Mol Cancer Ther 15:2598-2608 | 2016 |
| Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes. Geanes AR, Cho HP, Nance KD, McGowan KM, Conn PJ, Jones CK, Meiler J, Lindsley CW (2016) Bioorg Med Chem Lett 26:4487-4491 | 2016 |
| Imaging mass spectrometry assists in the classification of diagnostically challenging atypical Spitzoid neoplasms. Lazova R, Seeley EH, Kutzner H, Scolyer RA, Scott G, Cerroni L, Fried I, Kozovska ME, Rosenberg AS, Prieto VG, Shehata BM, Durham MM, Henry G, Rodriguez-Peralto JL, Riveiro-Falkenbach E, Schaefer JT, Danialan R, Fraitag S, Vollenweider-Roten S, Sepehr A, Sangueza M, Hijazi N, Corredoira Y, Kowal R, Harris OM, Bravo F, Boyd AS, Gueorguieva R, Caprioli RM (2016) J Am Acad Dermatol 75:1176-1186.e4 | 2016 |
| Protocols for Molecular Modeling with Rosetta3 and RosettaScripts. Bender BJ, Cisneros A, Duran AM, Finn JA, Fu D, Lokits AD, Mueller BK, Sangha AK, Sauer MF, Sevy AM, Sliwoski G, Sheehan JH, DiMaio F, Meiler J, Moretti R (2016) Biochemistry 55:4748-63 | 2016 |
| Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment. Saxon JA, Sherrill TP, Polosukhin VV, Sai J, Zaynagetdinov R, McLoed AG, Gulleman PM, Barham W, Cheng DS, Hunt RP, Gleaves LA, Richmond A, Young LR, Yull FE, Blackwell TS (2016) Oncoimmunology 5:e1168549 | 2016 |
| Coordinated movement, neuromuscular synaptogenesis and trans-synaptic signaling defects in Drosophila galactosemia models. Jumbo-Lucioni PP, Parkinson WM, Kopke DL, Broadie K (2016) Hum Mol Genet 25:3699-3714 | 2016 |
| Impact of cordon-bleu expression on actin cytoskeleton architecture and dynamics. Grega-Larson NE, Crawley SW, Tyska MJ (2016) Cytoskeleton (Hoboken) 73:670-679 | 2016 |
| A Conserved Hydrophobic Core in Gαi1 Regulates G Protein Activation and Release from Activated Receptor. Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE (2016) J Biol Chem 291:19674-86 | 2016 |
| Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Taneja N, Fenix AM, Rathbun L, Millis BA, Tyska MJ, Hehnly H, Burnette DT (2016) Sci Rep 6:29846 | 2016 |
| Loss of Serotonin Transporter Function Alters ADP-mediated Glycoprotein αIIbβ3 Activation through Dysregulation of the 5-HT2A Receptor. Oliver KH, Duvernay MT, Hamm HE, Carneiro AM (2016) J Biol Chem 291:20210-9 | 2016 |
| Cortactin promotes exosome secretion by controlling branched actin dynamics. Sinha S, Hoshino D, Hong NH, Kirkbride KC, Grega-Larson NE, Seiki M, Tyska MJ, Weaver AM (2016) J Cell Biol 214:197-213 | 2016 |
| Altered TGF-α/β signaling drives cooperation between breast cancer cell populations. Franco OE, Tyson DR, Konvinse KC, Udyavar AR, Estrada L, Quaranta V, Crawford SE, Hayward SW (2016) FASEB J 30:3441-3452 | 2016 |
| Telomerase, Autophagy and Acute Kidney Injury. Harris RC, Cheng H (2016) Nephron 134:145-148 | 2016 |
| Biomarker Tests for Molecularly Targeted Therapies--The Key to Unlocking Precision Medicine. Lyman GH, Moses HL (2016) N Engl J Med 375:4-6 | 2016 |
| Insights into the Genetic Basis of the Renal Cell Carcinomas from The Cancer Genome Atlas. Haake SM, Weyandt JD, Rathmell WK (2016) Mol Cancer Res 14:589-98 | 2016 |
| The Discovery and Early Days of TGF-β: A Historical Perspective. Moses HL, Roberts AB, Derynck R (2016) Cold Spring Harb Perspect Biol 8: | 2016 |
| Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer. McLoed AG, Sherrill TP, Cheng DS, Han W, Saxon JA, Gleaves LA, Wu P, Polosukhin VV, Karin M, Yull FE, Stathopoulos GT, Georgoulias V, Zaynagetdinov R, Blackwell TS (2016) Cell Rep 16:120-132 | 2016 |
| Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection. Lehmann BD, Jovanović B, Chen X, Estrada MV, Johnson KN, Shyr Y, Moses HL, Sanders ME, Pietenpol JA (2016) PLoS One 11:e0157368 | 2016 |
| The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction. Wakeman CA, Moore JL, Noto MJ, Zhang Y, Singleton MD, Prentice BM, Gilston BA, Doster RS, Gaddy JA, Chazin WJ, Caprioli RM, Skaar EP (2016) Nat Commun 7:11951 | 2016 |
| Standard Reticle Slide To Objectively Evaluate Spatial Resolution and Instrument Performance in Imaging Mass Spectrometry. Zubair F, Prentice BM, Norris JL, Laibinis PE, Caprioli RM (2016) Anal Chem 88:7302-11 | 2016 |
| Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis. Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP (2016) Laryngoscope 126:E356-E361 | 2016 |
| Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species. Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP (2017) Laryngoscope 127:179-185 | 2017 |
| Discovery of Small-Molecule Modulators of the Human Y4 Receptor. Sliwoski G, Schubert M, Stichel J, Weaver D, Beck-Sickinger AG, Meiler J (2016) PLoS One 11:e0157146 | 2016 |
| Combinatorial approach to cancer immunotherapy: strength in numbers. Vilgelm AE, Johnson DB, Richmond A (2016) J Leukoc Biol 100:275-90 | 2016 |
| A Derived Allosteric Switch Underlies the Evolution of Conditional Cooperativity between HOXA11 and FOXO1. Nnamani MC, Ganguly S, Erkenbrack EM, Lynch VJ, Mizoue LS, Tong Y, Darling HL, Fuxreiter M, Meiler J, Wagner GP (2016) Cell Rep 15:2097-2108 | 2016 |
| Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies. Shaver TM, Lehmann BD, Beeler JS, Li CI, Li Z, Jin H, Stricker TP, Shyr Y, Pietenpol JA (2016) Cancer Res 76:4850-60 | 2016 |
| Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion. Zeng F, Kloepfer LA, Finney C, Diedrich A, Harris RC (2016) Am J Physiol Renal Physiol 311:F695-F707 | 2016 |
| Tyrosine Kinase Signaling in Clear Cell and Papillary Renal Cell Carcinoma Revealed by Mass Spectrometry-Based Phosphotyrosine Proteomics. Haake SM, Li J, Bai Y, Kinose F, Fang B, Welsh EA, Zent R, Dhillon J, Pow-Sang JM, Chen YA, Koomen JM, Rathmell WK, Fishman M, Haura EB (2016) Clin Cancer Res 22:5605-5616 | 2016 |
| Extracellular chloride signals collagen IV network assembly during basement membrane formation. Cummings CF, Pedchenko V, Brown KL, Colon S, Rafi M, Jones-Paris C, Pokydeshava E, Liu M, Pastor-Pareja JC, Stothers C, Ero-Tolliver IA, McCall AS, Vanacore R, Bhave G, Santoro S, Blackwell TS, Zent R, Pozzi A, Hudson BG (2016) J Cell Biol 213:479-94 | 2016 |
| Integrin α1β1 protects against signs of post-traumatic osteoarthritis in the female murine knee partially via regulation of epidermal growth factor receptor signalling. Shin SY, Pozzi A, Boyd SK, Clark AL (2016) Osteoarthritis Cartilage 24:1795-1806 | 2016 |
| Changes in the Fracture Resistance of Bone with the Progression of Type 2 Diabetes in the ZDSD Rat. Creecy A, Uppuganti S, Merkel AR, O'Neal D, Makowski AJ, Granke M, Voziyan P, Nyman JS (2016) Calcif Tissue Int 99:289-301 | 2016 |
| Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice. Kang L, Mokshagundam S, Reuter B, Lark DS, Sneddon CC, Hennayake C, Williams AS, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH (2016) Diabetes 65:1590-600 | 2016 |
| Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy. Borza DB (2016) Front Immunol 7:157 | 2016 |
| Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. Skrypnyk NI, Voziyan P, Yang H, de Caestecker CR, Theberge MC, Drouin M, Hudson B, Harris RC, de Caestecker MP (2016) Am J Physiol Renal Physiol 311:F268-77 | 2016 |
| Using avatars to win the fight over BRAF inhibitor resistance. Vilgelm AE, Richmond A (2016) Pigment Cell Melanoma Res 29:398-9 | 2016 |
| ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS (2016) ACS Chem Neurosci 7:1013-23 | 2016 |
| Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints. Finn JA, Koehler Leman J, Willis JR, Cisneros A, Crowe JE, Meiler J (2016) PLoS One 11:e0154811 | 2016 |
| The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools. Figueroa M, Sleutel M, Vandevenne M, Parvizi G, Attout S, Jacquin O, Vandenameele J, Fischer AW, Damblon C, Goormaghtigh E, Valerio-Lepiniec M, Urvoas A, Durand D, Pardon E, Steyaert J, Minard P, Maes D, Meiler J, Matagne A, Martial JA, Van de Weerdt C (2016) J Struct Biol 195:19-30 | 2016 |
| Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury. Laskowski J, Renner B, Le Quintrec M, Panzer S, Hannan JP, Ljubanovic D, Ruseva MM, Borza DB, Antonioli AH, Pickering MC, Holers VM, Thurman JM (2016) Kidney Int 90:109-22 | 2016 |
| Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities. Pfaltzgraff ER, Roth GM, Miller PM, Gintzig AG, Ohi R, Bader DM (2016) Mol Biol Cell 27:1990-9 | 2016 |
| Celebrating the ASN at 50. Harris RC, Ibrahim T, Nath KA (2016) J Am Soc Nephrol 27:1575-6 | 2016 |
| An unbiased metric of antiproliferative drug effect in vitro. Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR (2016) Nat Methods 13:497-500 | 2016 |
| Pushing the size limit of de novo structure ensemble prediction guided by sparse SDSL-EPR restraints to 200 residues: The monomeric and homodimeric forms of BAX. Fischer AW, Bordignon E, Bleicken S, García-Sáez AJ, Jeschke G, Meiler J (2016) J Struct Biol 195:62-71 | 2016 |
| Rearrangement of the Extracellular Domain/Extracellular Loop 1 Interface Is Critical for Thyrotropin Receptor Activation. Schaarschmidt J, Nagel MB, Huth S, Jaeschke H, Moretti R, Hintze V, von Bergen M, Kalkhof S, Meiler J, Paschke R (2016) J Biol Chem 291:14095-108 | 2016 |
| Tumor Characteristics, Genetics, Management, and the Risk of Metastasis in Uveal Melanoma. Nichols EE, Richmond A, Daniels AB (2016) Semin Ophthalmol 31:304-9 | 2016 |
| Disparities in Uveal Melanoma: Patient Characteristics. Nichols EE, Richmond A, Daniels AB (2016) Semin Ophthalmol 31:296-303 | 2016 |
| Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Mont S, Davies SS, Roberts Second LJ, Mernaugh RL, McDonald WH, Segal BH, Zackert W, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Massion PP, Marnett LJ, Travis EL, Freeman ML (2016) Sci Rep 6:24919 | 2016 |
| Antibodies to α5 chain of collagen IV are pathogenic in Goodpasture's disease. Cui Z, Zhao MH, Jia XY, Wang M, Hu SY, Wang SX, Yu F, Brown KL, Hudson BG, Pedchenko V (2016) J Autoimmun 70:1-11 | 2016 |
| Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions. Zhang LS, Davies SS (2016) Genome Med 8:46 | 2016 |
| EGFR Fusions as Novel Therapeutic Targets in Lung Cancer. Konduri K, Gallant JN, Chae YK, Giles FJ, Gitlitz BJ, Gowen K, Ichihara E, Owonikoko TK, Peddareddigari V, Ramalingam SS, Reddy SK, Eaby-Sandy B, Vavalà T, Whiteley A, Chen H, Yan Y, Sheehan JH, Meiler J, Morosini D, Ross JS, Stephens PJ, Miller VA, Ali SM, Lovly CM (2016) Cancer Discov 6:601-11 | 2016 |
| Rosetta and the Design of Ligand Binding Sites. Moretti R, Bender BJ, Allison B, Meiler J (2016) Methods Mol Biol 1414:47-62 | 2016 |
| Silent Cerebral Small Vessel Disease in Restless Legs Syndrome. Ferri R, Cosentino FI, Moussouttas M, Lanuzza B, Aricò D, Bagai K, Wang L, McLaughlin B, Walters AS (2016) Sleep 39:1371-7 | 2016 |
| Erratum to: Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients. Ring BZ, Hout DR, Morris SW, Lawrence K, Schweitzer BL, Bailey DB, Lehmann BD, Pietenpol JA, Seitz RS (2016) BMC Cancer 16:275 | 2016 |
| Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM (2016) Nat Med 22:497-505 | 2016 |
| Biomarker Tests for Molecularly Targeted Therapies: Laying the Foundation and Fulfilling the Dream. Lyman GH, Moses HL (2016) J Clin Oncol 34:2061-6 | 2016 |
| Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. Weber MR, Zuka M, Lorger M, Tschan M, Torbett BE, Zijlstra A, Quigley JP, Staflin K, Eliceiri BP, Krueger JS, Marchese P, Ruggeri ZM, Felding BH (2016) Thromb Res 140 Suppl 1:S27-36 | 2016 |
| CASP11--An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline. Fischer AW, Heinze S, Putnam DK, Li B, Pino JC, Xia Y, Lopez CF, Meiler J (2016) PLoS One 11:e0152517 | 2016 |
| Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization. Willis JR, Finn JA, Briney B, Sapparapu G, Singh V, King H, LaBranche CC, Montefiori DC, Meiler J, Crowe JE (2016) Proc Natl Acad Sci U S A 113:4446-51 | 2016 |
| Immune activation caused by vascular oxidation promotes fibrosis and hypertension. Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, Davies SS, Roberts LJ, Madhur MS, Harrison DG (2016) J Clin Invest 126:1607 | 2016 |
| Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress. Federspiel JD, Codreanu SG, Palubinsky AM, Winland AJ, Betanzos CM, McLaughlin B, Liebler DC (2016) Mol Cell Proteomics 15:1947-61 | 2016 |
| The impact of bone morphogenetic protein 4 (BMP4) on breast cancer metastasis in a mouse xenograft model. Ampuja M, Alarmo EL, Owens P, Havunen R, Gorska AE, Moses HL, Kallioniemi A (2016) Cancer Lett 375:238-244 | 2016 |
| Origin and prediction of free-solution interaction studies performed label-free. Bornhop DJ, Kammer MN, Kussrow A, Flowers RA, Meiler J (2016) Proc Natl Acad Sci U S A 113:E1595-604 | 2016 |
| Structure and mechanism of the phage T4 recombination mediator protein UvsY. Gajewski S, Waddell MB, Vaithiyalingam S, Nourse A, Li Z, Woetzel N, Alexander N, Meiler J, White SW (2016) Proc Natl Acad Sci U S A 113:3275-80 | 2016 |
| Data publication with the structural biology data grid supports live analysis. Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P (2016) Nat Commun 7:10882 | 2016 |
| p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network. Marshall CB, Mays DJ, Beeler JS, Rosenbluth JM, Boyd KL, Santos Guasch GL, Shaver TM, Tang LJ, Liu Q, Shyr Y, Venters BJ, Magnuson MA, Pietenpol JA (2016) Cell Rep 14:2289-300 | 2016 |
| The role of NF-kB in modulating antitumor immunity. Richmond A, Yang J (2016) Oncoimmunology 5:e1005522 | 2016 |
| Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model. Parkinson WM, Dookwah M, Dear ML, Gatto CL, Aoki K, Tiemeyer M, Broadie K (2016) Dis Model Mech 9:513-27 | 2016 |
| Novel methods for microCT-based analyses of vasculature in the renal cortex reveal a loss of perfusable arterioles and glomeruli in eNOS-/- mice. Perrien DS, Saleh MA, Takahashi K, Madhur MS, Harrison DG, Harris RC, Takahashi T (2016) BMC Nephrol 17:24 | 2016 |
| Study of Chemotaxis and Cell-Cell Interactions in Cancer with Microfluidic Devices. Sai J, Rogers M, Hockemeyer K, Wikswo JP, Richmond A (2016) Methods Enzymol 570:19-45 | 2016 |
| Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients. Ring BZ, Hout DR, Morris SW, Lawrence K, Schweitzer BL, Bailey DB, Lehmann BD, Pietenpol JA, Seitz RS (2016) BMC Cancer 16:143 | 2016 |
| BVES Regulates Intestinal Stem Cell Programs and Intestinal Crypt Viability after Radiation. Reddy VK, Short SP, Barrett CW, Mittal MK, Keating CE, Thompson JJ, Harris EI, Revetta F, Bader DM, Brand T, Washington MK, Williams CS (2016) Stem Cells 34:1626-36 | 2016 |
| Identification of a Substrate Recognition Domain in the Replication Stress Response Protein Zinc Finger Ran-binding Domain-containing Protein 3 (ZRANB3). Badu-Nkansah A, Mason AC, Eichman BF, Cortez D (2016) J Biol Chem 291:8251-7 | 2016 |
| 3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated optic glioma. Anderson DM, Van de Plas R, Rose KL, Hill S, Schey KL, Solga AC, Gutmann DH, Caprioli RM (2016) J Proteomics 149:77-84 | 2016 |
| Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma. Marien E, Meister M, Muley T, Gomez Del Pulgar T, Derua R, Spraggins JM, Van de Plas R, Vanderhoydonc F, Machiels J, Binda MM, Dehairs J, Willette-Brown J, Hu Y, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Lacal JC, Waelkens E, Swinnen JV (2016) Oncotarget 7:12582-97 | 2016 |
| Pragmatic pharmacology: population pharmacokinetic analysis of fentanyl using remnant samples from children after cardiac surgery. Van Driest SL, Marshall MD, Hachey B, Beck C, Crum K, Owen J, Smith AH, Kannankeril PJ, Woodworth A, Caprioli RM, Choi L (2016) Br J Clin Pharmacol 81:1165-74 | 2016 |
| Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry. Doll CA, Broadie K (2016) Neurobiol Dis 89:76-87 | 2016 |
| Improving quantitative structure-activity relationship models using Artificial Neural Networks trained with dropout. Mendenhall J, Meiler J (2016) J Comput Aided Mol Des 30:177-89 | 2016 |
| Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2. Jerrell RJ, Parekh A (2016) Biomaterials 84:119-29 | 2016 |
| Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, Irish JM, Shyr Y, Sullivan RJ, Puzanov I, Sosman JA, Balko JM (2016) Nat Commun 7:10582 | 2016 |
| Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. Theodosiou M, Widmaier M, Böttcher RT, Rognoni E, Veelders M, Bharadwaj M, Lambacher A, Austen K, Müller DJ, Zent R, Fässler R (2016) Elife 5:e10130 | 2016 |
| Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss. Jolly LA, Novitskiy S, Owens P, Massoll N, Cheng N, Fang W, Moses HL, Franco AT (2016) Cancer Res 76:1804-13 | 2016 |
| Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues. Chumbley CW, Reyzer ML, Allen JL, Marriner GA, Via LE, Barry CE, Caprioli RM (2016) Anal Chem 88:2392-8 | 2016 |
| ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation. Crawley SW, Weck ML, Grega-Larson NE, Shifrin DA, Tyska MJ (2016) Dev Cell 36:190-200 | 2016 |
| Accurate Prediction of Contact Numbers for Multi-Spanning Helical Membrane Proteins. Li B, Mendenhall J, Nguyen ED, Weiner BE, Fischer AW, Meiler J (2016) J Chem Inf Model 56:423-34 | 2016 |
| Effects of Recombinant Human Bone Morphogenetic Protein-2 Dose and Ceramic Composition on New Bone Formation and Space Maintenance in a Canine Mandibular Ridge Saddle Defect Model. Talley AD, Kalpakci KN, Shimko DA, Zienkiewicz KJ, Cochran DL, Guelcher SA (2016) Tissue Eng Part A 22:469-79 | 2016 |
| Protonation-dependent conformational dynamics of the multidrug transporter EmrE. Dastvan R, Fischer AW, Mishra S, Meiler J, Mchaourab HS (2016) Proc Natl Acad Sci U S A 113:1220-5 | 2016 |
| Serum Metabolite Profiles Are Altered by Erlotinib Treatment and the Integrin α1-Null Genotype but Not by Post-Traumatic Osteoarthritis. Mickiewicz B, Shin SY, Pozzi A, Vogel HJ, Clark AL (2016) J Proteome Res 15:815-25 | 2016 |
| NO clue to pathogenesis of aristolochic acid nephropathy. Gewin L (2016) Exp Physiol 101:33 | 2016 |
| p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment. Saxon JA, Cheng DS, Han W, Polosukhin VV, McLoed AG, Richmond BW, Gleaves LA, Tanjore H, Sherrill TP, Barham W, Yull FE, Blackwell TS (2016) J Immunol 196:1891-9 | 2016 |
| Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs. Zaynagetdinov R, Sherrill TP, Gleaves LA, Hunt P, Han W, McLoed AG, Saxon JA, Tanjore H, Gulleman PM, Young LR, Blackwell TS (2016) Oncotarget 7:5470-82 | 2016 |
| Deleting the TGF-β receptor in proximal tubules impairs HGF signaling. Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L (2016) Am J Physiol Renal Physiol 310:F499-510 | 2016 |
| Characterization of the Domain Orientations of E. coli 5'-Nucleotidase by Fitting an Ensemble of Conformers to DEER Distance Distributions. Krug U, Alexander NS, Stein RA, Keim A, Mchaourab HS, Sträter N, Meiler J (2016) Structure 24:43-56 | 2016 |
| Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign. Sliwoski G, Mendenhall J, Meiler J (2016) J Comput Aided Mol Des 30:209-17 | 2016 |
| A Phenome-Wide Association Study Identifies a Novel Asthma Risk Locus Near TERC. Claar DD, Larkin EK, Bastarache L, Blackwell TS, Loyd JE, Hartert TV, Denny JC, Kropski JA (2016) Am J Respir Crit Care Med 193:98-100 | 2016 |
| Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients. Choma DP, Vanacore R, Naylor H, Zimmerman IA, Pavlichenko A, Pavlichenko A, Foye L, Carbone DP, Harris RC, Dikov MM, Tchekneva EE (2016) Am J Physiol Renal Physiol 310:F416-25 | 2016 |
| Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment. Vilgelm AE, Johnson CA, Prasad N, Yang J, Chen SC, Ayers GD, Pawlikowski JS, Raman D, Sosman JA, Kelley M, Ecsedy JA, Shyr Y, Levy SE, Richmond A (2016) J Natl Cancer Inst 108:djv406 | 2016 |
| A fully automated Drosophila olfactory classical conditioning and testing system for behavioral learning and memory assessment. Jiang H, Hanna E, Gatto CL, Page TL, Bhuva B, Broadie K (2016) J Neurosci Methods 261:62-74 | 2016 |
| Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis. Bryant AJ, Robinson LJ, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, McClellan LJ, Polosukhin VV, Tanjore H, McConaha ME, Gleaves LA, Talati MA, Hemnes AR, Fessel JP, Lawson WE, Blackwell TS, West JD (2015) Pulm Circ 5:681-90 | 2015 |
| Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension. Wu J, Montaniel KR, Saleh MA, Xiao L, Chen W, Owens GK, Humphrey JD, Majesky MW, Paik DT, Hatzopoulos AK, Madhur MS, Harrison DG (2016) Hypertension 67:461-8 | 2016 |
| KIM-1/TIM-1 in proximal tubular cell immune response. Brooks CR, Bonventre JV (2015) Oncotarget 6:44059-60 | 2015 |
| Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma. Hover LD, Owens P, Munden AL, Wang J, Chambless LB, Hopkins CR, Hong CC, Moses HL, Abel TW (2016) Neuro Oncol 18:928-38 | 2016 |
| Personalizing Therapy in Idiopathic Pulmonary Fibrosis: A Glimpse of the Future? Kropski JA, Lawson WE, Blackwell TS (2015) Am J Respir Crit Care Med 192:1409-11 | 2015 |
| MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer. Edmonds MD, Boyd KL, Moyo T, Mitra R, Duszynski R, Arrate MP, Chen X, Zhao Z, Blackwell TS, Andl T, Eischen CM (2016) J Clin Invest 126:349-64 | 2016 |
| Bone Marrow-derived Cells Contribute to the Pathogenesis of Pulmonary Arterial Hypertension. Yan L, Chen X, Talati M, Nunley BW, Gladson S, Blackwell T, Cogan J, Austin E, Wheeler F, Loyd J, West J, Hamid R (2016) Am J Respir Crit Care Med 193:898-909 | 2016 |
| Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension. Bryant AJ, Carrick RP, McConaha ME, Jones BR, Shay SD, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, Tanjore H, Hemnes AR, Karwandyar AK, Polosukhin VV, Talati MA, Dong HJ, Gleaves LA, Carrier EJ, Gaskill C, Scott EW, Majka SM, Fessel JP, Haase VH, West JD, Blackwell TS, Lawson WE (2016) Am J Physiol Lung Cell Mol Physiol 310:L249-62 | 2016 |
| Vinculin controls talin engagement with the actomyosin machinery. Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C (2015) Nat Commun 6:10038 | 2015 |
| Cell Receptor-Basement Membrane Interactions in Health and Disease: A Kidney-Centric View. Borza CM, Chen X, Zent R, Pozzi A (2015) Curr Top Membr 76:231-53 | 2015 |
| Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis. Dear ML, Dani N, Parkinson W, Zhou S, Broadie K (2016) Development 143:75-87 | 2016 |
| Comprehensive Characterization of Glycosylation and Hydroxylation of Basement Membrane Collagen IV by High-Resolution Mass Spectrometry. Basak T, Vega-Montoto L, Zimmerman LJ, Tabb DL, Hudson BG, Vanacore RM (2016) J Proteome Res 15:245-58 | 2016 |
| p120-catenin controls contractility along the vertical axis of epithelial lateral membranes. Yu HH, Dohn MR, Markham NO, Coffey RJ, Reynolds AB (2016) J Cell Sci 129:80-94 | 2016 |
| A Structural Study of CESA1 Catalytic Domain of Arabidopsis Cellulose Synthesis Complex: Evidence for CESA Trimers. Vandavasi VG, Putnam DK, Zhang Q, Petridis L, Heller WT, Nixon BT, Haigler CH, Kalluri U, Coates L, Langan P, Smith JC, Meiler J, O'Neill H (2016) Plant Physiol 170:123-35 | 2016 |
| Regulation of invadopodia by mechanical signaling. Parekh A, Weaver AM (2016) Exp Cell Res 343:89-95 | 2016 |
| Patients with ClearCode34-identified molecular subtypes of clear cell renal cell carcinoma represent unique populations with distinct comorbidities. Haake SM, Brooks SA, Welsh E, Fulp WJ, Chen DT, Dhillon J, Haura E, Sexton W, Spiess PE, Pow-Sang J, Rathmell WK, Fishman M (2016) Urol Oncol 34:122.e1-7 | 2016 |
| Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities. Khan IS, Odom M, Ehtesham M, Colvin D, Quarles CC, McLaughlin B, Singer RJ (2016) J Neurosurg 125:152-9 | 2016 |
| RNAseq by Total RNA Library Identifies Additional RNAs Compared to Poly(A) RNA Library. Guo Y, Zhao S, Sheng Q, Guo M, Lehmann B, Pietenpol J, Samuels DC, Shyr Y (2015) Biomed Res Int 2015:862130 | 2015 |
| Chemokine Regulation of Neutrophil Infiltration of Skin Wounds. Su Y, Richmond A (2015) Adv Wound Care (New Rochelle) 4:631-640 | 2015 |
| Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. Cancer Genome Atlas Research Network, Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, Rathmell WK, Brooks AN, Hoadley KA, Robertson AG, Brooks D, Bowlby R, Sadeghi S, Shen H, Weisenberger DJ, Bootwalla M, Baylin SB, Laird PW, Cherniack AD, Saksena G, Haake S, Li J, Liang H, Lu Y, Mills GB, Akbani R, Leiserson MD, Raphael BJ, Anur P, Bottaro D, Albiges L, Barnabas N, Choueiri TK, Czerniak B, Godwin AK, Hakimi AA, Ho TH, Hsieh J, Ittmann M, Kim WY, Krishnan B, Merino MJ, Mills Shaw KR, Reuter VE, Reznik E, Shelley CS, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Tickoo S, Burnett K, Crain D, Gardner J, Lau K, Mallery D, Morris S, Paulauskis JD, Penny RJ, Shelton C, Shelton WT, Sherman M, Thompson E, Yena P, Avedon MT, Bowen J, Gastier-Foster JM, Gerken M, Leraas KM, Lichtenberg TM, Ramirez NC, Santos T, Wise L, Zmuda E, Demchok JA, Felau I, Hutter CM, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Zhang J, Ayala B, Baboud J, Chudamani S, Liu J, Lolla L, Naresh R, Pihl T, Sun Q, Wan Y, Wu Y, Ally A, Balasundaram M, Balu S, Beroukhim R, Bodenheimer T, Buhay C, Butterfield YS, Carlsen R, Carter SL, Chao H, Chuah E, Clarke A, Covington KR, Dahdouli M, Dewal N, Dhalla N, Doddapaneni HV, Drummond JA, Gabriel SB, Gibbs RA, Guin R, Hale W, Hawes A, Hayes DN, Holt RA, Hoyle AP, Jefferys SR, Jones SJ, Jones CD, Kalra D, Kovar C, Lewis L, Li J, Ma Y, Marra MA, Mayo M, Meng S, Meyerson M, Mieczkowski PA, Moore RA, Morton D, Mose LE, Mungall AJ, Muzny D, Parker JS, Perou CM, Roach J, Schein JE, Schumacher SE, Shi Y, Simons JV, Sipahimalani P, Skelly T, Soloway MG, Sougnez C, Tam A, Tan D, Thiessen N, Veluvolu U, Wang M, Wilkerson MD, Wong T, Wu J, Xi L, Zhou J, Bedford J, Chen F, Fu Y, Gerstein M, Haussler D, Kasaian K, Lai P, Ling S, Radenbaugh A, Van Den Berg D, Weinstein JN, Zhu J, Albert M, Alexopoulou I, Andersen JJ, Auman JT, Bartlett J, Bastacky S, Bergsten J, Blute ML, Boice L, Bollag RJ, Boyd J, Castle E, Chen YB, Cheville JC, Curley E, Davies B, DeVolk A, Dhir R, Dike L, Eckman J, Engel J, Harr J, Hrebinko R, Huang M, Huelsenbeck-Dill L, Iacocca M, Jacobs B, Lobis M, Maranchie JK, McMeekin S, Myers J, Nelson J, Parfitt J, Parwani A, Petrelli N, Rabeno B, Roy S, Salner AL, Slaton J, Stanton M, Thompson RH, Thorne L, Tucker K, Weinberger PM, Winemiller C, Zach LA, Zuna R (2016) N Engl J Med 374:135-45 | 2016 |
| The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Mullins EA, Shi R, Parsons ZD, Yuen PK, David SS, Igarashi Y, Eichman BF (2015) Nature 527:254-8 | 2015 |
| Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Austen K, Ringer P, Mehlich A, Chrostek-Grashoff A, Kluger C, Klingner C, Sabass B, Zent R, Rief M, Grashoff C (2015) Nat Cell Biol 17:1597-606 | 2015 |
| Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo. Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS (2015) Mol Syst Biol 11:835 | 2015 |
| High efficacy vasopermeability drug candidates identified by screening in an ex ovo chorioallantoic membrane model. Pink D, Luhrs KA, Zhou L, Schulte W, Chase J, Frosch C, Haberl U, Nguyen V, Roy AI, Lewis JD, Zijlstra A, Parseghian MH (2015) Sci Rep 5:15756 | 2015 |
| Decellularization of intact tissue enables MALDI imaging mass spectrometry analysis of the extracellular matrix. Gessel M, Spraggins JM, Voziyan P, Hudson BG, Caprioli RM (2015) J Mass Spectrom 50:1288-93 | 2015 |
| Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury. Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV (2015) EBioMedicine 2:1090-101 | 2015 |
| Interprofessional projects promote and strengthen interdisciplinary collaboration. Pfaltzgraff ER, Samade R, Adams R, Levic DS, Bader DM, Fleming AE (2015) Med Educ 49:1156-7 | 2015 |
| Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV (2015) Nat Commun 6:8715 | 2015 |
| Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development. Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R (2015) J Cell Sci 128:4293-305 | 2015 |
| The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice. Ceddia RP, Lee D, Maulis MF, Carboneau BA, Threadgill DW, Poffenberger G, Milne G, Boyd KL, Powers AC, McGuinness OP, Gannon M, Breyer RM (2016) Endocrinology 157:220-32 | 2016 |
| BCL::Conf: small molecule conformational sampling using a knowledge based rotamer library. Kothiwale S, Mendenhall JL, Meiler J (2015) J Cheminform 7:47 | 2015 |
| Urinary oncofetal ED-A fibronectin correlates with poor prognosis in patients with bladder cancer. Arnold SA, Loomans HA, Ketova T, Andl CD, Clark PE, Zijlstra A (2016) Clin Exp Metastasis 33:29-44 | 2016 |
| Histology-guided protein digestion/extraction from formalin-fixed and paraffin-embedded pressure ulcer biopsies. Taverna D, Pollins AC, Nanney LB, Sindona G, Caprioli RM (2016) Exp Dermatol 25:143-6 | 2016 |
| Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease. Du RH, Richmond BW, Blackwell TS, Cates JM, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS, Polosukhin VV (2015) Virchows Arch 467:657-665 | 2015 |
| Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ. Barham W, Chen L, Tikhomirov O, Onishko H, Gleaves L, Stricker TP, Blackwell TS, Yull FE (2015) BMC Cancer 15:647 | 2015 |
| Clinical Relevance of Biomarkers of Oxidative Stress. Frijhoff J, Winyard PG, Zarkovic N, Davies SS, Stocker R, Cheng D, Knight AR, Taylor EL, Oettrich J, Ruskovska T, Gasparovic AC, Cuadrado A, Weber D, Poulsen HE, Grune T, Schmidt HH, Ghezzi P (2015) Antioxid Redox Signal 23:1144-70 | 2015 |
| Substrate modulus of 3D-printed scaffolds regulates the regenerative response in subcutaneous implants through the macrophage phenotype and Wnt signaling. Guo R, Merkel AR, Sterling JA, Davidson JM, Guelcher SA (2015) Biomaterials 73:85-95 | 2015 |
| Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses. Vilgelm A, Richmond A (2015) Oncoimmunology 4:e1009299 | 2015 |
| NF-κB-dependent airway inflammation triggers systemic insulin resistance. Cyphert TJ, Morris RT, House LM, Barnes TM, Otero YF, Barham WJ, Hunt RP, Zaynagetdinov R, Yull FE, Blackwell TS, McGuinness OP (2015) Am J Physiol Regul Integr Comp Physiol 309:R1144-52 | 2015 |
| Cordon bleu promotes the assembly of brush border microvilli. Grega-Larson NE, Crawley SW, Erwin AL, Tyska MJ (2015) Mol Biol Cell 26:3803-15 | 2015 |
| Injected biodegradable polyurethane scaffolds support tissue infiltration and delay wound contraction in a porcine excisional model. Adolph EJ, Guo R, Pollins AC, Zienkiewicz K, Cardwell N, Davidson JM, Guelcher SA, Nanney LB (2016) J Biomed Mater Res B Appl Biomater 104:1679-1690 | 2016 |
| Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis. Paik DT, Rai M, Ryzhov S, Sanders LN, Aisagbonhi O, Funke MJ, Feoktistov I, Hatzopoulos AK (2015) Circ Res 117:804-16 | 2015 |
| Degradation of polypropylene in vivo: A microscopic analysis of meshes explanted from patients. Iakovlev VV, Guelcher SA, Bendavid R (2017) J Biomed Mater Res B Appl Biomater 105:237-248 | 2017 |
| Altering adsorbed proteins or cellular gene expression in bone-metastatic cancer cells affects PTHrP and Gli2 without altering cell growth. Page JM, Merkel AR, Ruppender NS, Guo R, Dadwal UC, Cannonier S, Basu S, Guelcher SA, Sterling JA (2015) Data Brief 4:440-6 | 2015 |
| EGFR Kinase Domain Duplication (EGFR-KDD) Is a Novel Oncogenic Driver in Lung Cancer That Is Clinically Responsive to Afatinib. Gallant JN, Sheehan JH, Shaver TM, Bailey M, Lipson D, Chandramohan R, Red Brewer M, York SJ, Kris MG, Pietenpol JA, Ladanyi M, Miller VA, Ali SM, Meiler J, Lovly CM (2015) Cancer Discov 5:1155-63 | 2015 |
| KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV (2015) EMBO J 34:2441-64 | 2015 |
| Compressive fatigue and fracture toughness behavior of injectable, settable bone cements. Harmata AJ, Uppuganti S, Granke M, Guelcher SA, Nyman JS (2015) J Mech Behav Biomed Mater 51:345-55 | 2015 |
| Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis. Pickup MW, Hover LD, Guo Y, Gorska AE, Chytil A, Novitskiy SV, Moses HL, Owens P (2015) Oncotarget 6:22890-904 | 2015 |
| TRIzol and Alu qPCR-based quantification of metastatic seeding within the skeleton. Preston Campbell J, Mulcrone P, Masood SK, Karolak M, Merkel A, Hebron K, Zijlstra A, Sterling J, Elefteriou F (2015) Sci Rep 5:12635 | 2015 |
| Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. Nagathihalli NS, Castellanos JA, Shi C, Beesetty Y, Reyzer ML, Caprioli R, Chen X, Walsh AJ, Skala MC, Moses HL, Merchant NB (2015) Gastroenterology 149:1932-1943.e9 | 2015 |
| Clinical implications of molecular heterogeneity in triple negative breast cancer. Lehmann BD, Pietenpol JA (2015) Breast 24 Suppl 2:S36-40 | 2015 |
| Mitochondria sequence mapping strategies and practicability of mitochondria variant detection from exome and RNA sequencing data. Zhang P, Samuels DC, Lehmann B, Stricker T, Pietenpol J, Shyr Y, Guo Y (2016) Brief Bioinform 17:224-32 | 2016 |
| Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis. Fata CR, Seeley EH, Desouki MM, Du L, Gwin K, Hanley KZ, Hecht JL, Jarboe EA, Liang SX, Parkash V, Quick CM, Zheng W, Shyr Y, Caprioli RM, Fadare O (2015) Hum Pathol 46:1427-36 | 2015 |
| Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth. Hover LD, Young CD, Bhola NE, Wilson AJ, Khabele D, Hong CC, Moses HL, Owens P (2015) Cancer Lett 368:79-87 | 2015 |
| Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand. DeLuca S, Khar K, Meiler J (2015) PLoS One 10:e0132508 | 2015 |
| D-amino acid inhibits biofilm but not new bone formation in an ovine model. Harmata AJ, Ma Y, Sanchez CJ, Zienkiewicz KJ, Elefteriou F, Wenke JC, Guelcher SA (2015) Clin Orthop Relat Res 473:3951-61 | 2015 |
| Facilitated diffusion framework for transcription factor search with conformational changes. Cartailler J, Reingruber J (2015) Phys Biol 12:046012 | 2015 |
| Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling. Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD (2015) J Invest Dermatol 135:2902 | 2015 |
| The Ancient Immunoglobulin Domains of Peroxidasin Are Required to Form Sulfilimine Cross-links in Collagen IV. Ero-Tolliver IA, Hudson BG, Bhave G (2015) J Biol Chem 290:21741-8 | 2015 |
| Pyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo. Madu H, Avance J, Chetyrkin S, Darris C, Rose KL, Sanchez OA, Hudson B, Voziyan P (2015) Free Radic Biol Med 89:83-90 | 2015 |
| Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models. Liu Y, Hawkins OE, Vilgelm AE, Pawlikowski JS, Ecsedy JA, Sosman JA, Kelley MC, Richmond A (2015) Clin Cancer Res 21:5338-48 | 2015 |
| High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling. Prentice BM, Chumbley CW, Caprioli RM (2015) J Mass Spectrom 50:703-10 | 2015 |
| A conserved role of αA-crystallin in the development of the zebrafish embryonic lens. Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS (2015) Exp Eye Res 138:104-13 | 2015 |
| Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences. Sevy AM, Jacobs TM, Crowe JE, Meiler J (2015) PLoS Comput Biol 11:e1004300 | 2015 |
| Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry. Zhao W, Vaithiyalingam S, San Filippo J, Maranon DG, Jimenez-Sainz J, Fontenay GV, Kwon Y, Leung SG, Lu L, Jensen RB, Chazin WJ, Wiese C, Sung P (2015) Mol Cell 59:176-87 | 2015 |
| Fabrication of 3D Scaffolds with Precisely Controlled Substrate Modulus and Pore Size by Templated-Fused Deposition Modeling to Direct Osteogenic Differentiation. Guo R, Lu S, Page JM, Merkel AR, Basu S, Sterling JA, Guelcher SA (2015) Adv Healthc Mater 4:1826-32 | 2015 |
| Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin β3 and TGF-β receptor type II. Page JM, Merkel AR, Ruppender NS, Guo R, Dadwal UC, Cannonier S, Basu S, Guelcher SA, Sterling JA (2015) Biomaterials 64:33-44 | 2015 |
| Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. Sali A, Berman HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, Markley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di Maio F, Ferrin TE, Grünewald K, Gutmanas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, Marti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD (2015) Structure 23:1156-67 | 2015 |
| Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition. An H, Stoops SL, Deane NG, Zhu J, Zi J, Weaver C, Waterson AG, Zijlstra A, Lindsley CW, Beauchamp RD (2015) Oncotarget 6:22934-48 | 2015 |
| EXIMS: an improved data analysis pipeline based on a new peak picking method for EXploring Imaging Mass Spectrometry data. Wijetunge CD, Saeed I, Boughton BA, Spraggins JM, Caprioli RM, Bacic A, Roessner U, Halgamuge SK (2015) Bioinformatics 31:3198-206 | 2015 |
| HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal. Kile AC, Chavez DA, Bacal J, Eldirany S, Korzhnev DM, Bezsonova I, Eichman BF, Cimprich KA (2015) Mol Cell 58:1090-100 | 2015 |
| 5'-O-Alkylpyridoxamines: Lipophilic Analogues of Pyridoxamine Are Potent Scavengers of 1,2-Dicarbonyls. Amarnath V, Amarnath K, Avance J, Stec DF, Voziyan P (2015) Chem Res Toxicol 28:1469-75 | 2015 |
| Predicting in vivo glioma growth with the reaction diffusion equation constrained by quantitative magnetic resonance imaging data. Hormuth DA, Weis JA, Barnes SL, Miga MI, Rericha EC, Quaranta V, Yankeelov TE (2015) Phys Biol 12:046006 | 2015 |
| Notch Transmembrane Domain: Secondary Structure and Topology. Deatherage CL, Lu Z, Kim JH, Sanders CR (2015) Biochemistry 54:3565-8 | 2015 |
| BCL::SAXS: GPU accelerated Debye method for computation of small angle X-ray scattering profiles. Putnam DK, Weiner BE, Woetzel N, Lowe EW, Meiler J (2015) Proteins 83:1500-12 | 2015 |
| Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways. Chang J, Xue M, Yang S, Yao B, Zhang B, Chen X, Pozzi A, Zhang MZ (2015) PLoS One 10:e0127030 | 2015 |
| Triple-negative breast cancer: molecular subtypes and new targets for therapy. Lehmann BD, Pietenpol JA, Tan AR (2015) Am Soc Clin Oncol Educ Book :e31-9 | 2015 |
| Congenital nevi versus metastatic melanoma in a newborn to a mother with malignant melanoma - diagnosis supported by sex chromosome analysis and Imaging Mass Spectrometry. Alomari AK, Glusac EJ, Choi J, Hui P, Seeley EH, Caprioli RM, Watsky KL, Urban J, Lazova R (2015) J Cutan Pathol 42:757-64 | 2015 |
| Protein structure prediction guided by crosslinking restraints--A systematic evaluation of the impact of the crosslinking spacer length. Hofmann T, Fischer AW, Meiler J, Kalkhof S (2015) Methods 89:79-90 | 2015 |
| LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Duvall-Noelle N, Karwandyar A, Richmond A, Raman D (2016) Oncogene 35:1122-33 | 2016 |
| A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases. Mullins EA, Shi R, Kotsch LA, Eichman BF (2015) PLoS One 10:e0127733 | 2015 |
| Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer. Wilson AJ, Fadare O, Beeghly-Fadiel A, Son DS, Liu Q, Zhao S, Saskowski J, Uddin MJ, Daniel C, Crews B, Lehmann BD, Pietenpol JA, Crispens MA, Marnett LJ, Khabele D (2015) Oncotarget 6:21353-68 | 2015 |
| Directional cell movement through tissues is controlled by exosome secretion. Sung BH, Ketova T, Hoshino D, Zijlstra A, Weaver AM (2015) Nat Commun 6:7164 | 2015 |
| A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments. Mohni KN, Thompson PS, Luzwick JW, Glick GG, Pendleton CS, Lehmann BD, Pietenpol JA, Cortez D (2015) PLoS One 10:e0125482 | 2015 |
| A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor. Yi Y, Polosukhina D, Love HD, Hembd A, Pickup M, Moses HL, Lovvorn HN, Zent R, Clark PE (2015) J Urol 194:1762-70 | 2015 |
| Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y₂ Receptor Binding and Activation. Kaiser A, Müller P, Zellmann T, Scheidt HA, Thomas L, Bosse M, Meier R, Meiler J, Huster D, Beck-Sickinger AG, Schmidt P (2015) Angew Chem Int Ed Engl 54:7446-9 | 2015 |
| A transient cell-shielding method for viable MSC delivery within hydrophobic scaffolds polymerized in situ. Guo R, Ward CL, Davidson JM, Duvall CL, Wenke JC, Guelcher SA (2015) Biomaterials 54:21-33 | 2015 |
| MALDI FTICR IMS of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data. Spraggins JM, Rizzo DG, Moore JL, Rose KL, Hammer ND, Skaar EP, Caprioli RM (2015) J Am Soc Mass Spectrom 26:974-85 | 2015 |
| Static and cyclic mechanical loading of mesenchymal stem cells on elastomeric, electrospun polyurethane meshes. Cardwell RD, Kluge JA, Thayer PS, Guelcher SA, Dahlgren LA, Kaplan DL, Goldstein AS (2015) J Biomech Eng 137: | 2015 |
| Peptide spectra in Wilms tumor that associate with adverse outcomes. Murphy AJ, Pierce J, Seeley EH, Sullivan LM, Ruchelli ED, Nance ML, Caprioli RM, Lovvorn HN (2015) J Surg Res 196:332-8 | 2015 |
| Perspective on computational and structural aspects of kinase discovery from IPK2014. Martin E, Knapp S, Engh RA, Moebitz H, Varin T, Roux B, Meiler J, Berdini V, Baumann A, Vieth M (2015) Biochim Biophys Acta 1854:1595-604 | 2015 |
| Correction to differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine. Szulik MW, Pallan PS, Nocek B, Voehler M, Banerjee S, Brooks S, Joachimiak A, Egli M, Eichman BF, Stone MP (2015) Biochemistry 54:2550 | 2015 |
| Personalized biochemistry and biophysics. Kroncke BM, Vanoye CG, Meiler J, George AL, Sanders CR (2015) Biochemistry 54:2551-9 | 2015 |
| Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design. Burke JP, Bian Z, Shaw S, Zhao B, Goodwin CM, Belmar J, Browning CF, Vigil D, Friberg A, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW (2015) J Med Chem 58:3794-805 | 2015 |
| BCL::MP-fold: Membrane protein structure prediction guided by EPR restraints. Fischer AW, Alexander NS, Woetzel N, Karakas M, Weiner BE, Meiler J (2015) Proteins 83:1947-62 | 2015 |
| Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling. Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD (2015) J Invest Dermatol 135:2093-2101 | 2015 |
| Macrophages in vascular inflammation--From atherosclerosis to vasculitis. Shirai T, Hilhorst M, Harrison DG, Goronzy JJ, Weyand CM (2015) Autoimmunity 48:139-51 | 2015 |
| Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Yazlovitskaya EM, Tseng HY, Viquez O, Tu T, Mernaugh G, McKee KK, Riggins K, Quaranta V, Pathak A, Carter BD, Yurchenco P, Sonnenberg A, Böttcher RT, Pozzi A, Zent R (2015) Mol Biol Cell 26:1857-74 | 2015 |
| Activity-dependent FMRP requirements in development of the neural circuitry of learning and memory. Doll CA, Broadie K (2015) Development 142:1346-56 | 2015 |
| Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin. Vortmeier G, DeLuca SH, Els-Heindl S, Chollet C, Scheidt HA, Beck-Sickinger AG, Meiler J, Huster D (2015) PLoS One 10:e0122444 | 2015 |
| Imaging mass spectrometry: enabling a new age of discovery in biology and medicine through molecular microscopy. Caprioli RM (2015) J Am Soc Mass Spectrom 26:850-2 | 2015 |
| Investigating the Effects of Surface-Initiated Polymerization of ε-Caprolactone to Bioactive Glass Particles on the Mechanical Properties of Settable Polymer/Ceramic Composites. Harmata AJ, Ward CL, Zienkiewicz KJ, Wenke JC, Guelcher SA (2014) J Mater Res 29:2398-2407 | 2014 |
| Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles. Marien E, Meister M, Muley T, Fieuws S, Bordel S, Derua R, Spraggins J, Van de Plas R, Dehairs J, Wouters J, Bagadi M, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Waelkens E, Swinnen JV (2015) Int J Cancer 137:1539-48 | 2015 |
| High spatial resolution proteomic comparison of the brain in humans and chimpanzees. Bauernfeind AL, Reyzer ML, Caprioli RM, Ely JJ, Babbitt CC, Wray GA, Hof PR, Sherwood CC (2015) J Comp Neurol 523:2043-61 | 2015 |
| p120-catenin expressed in alveolar type II cells is essential for the regulation of lung innate immune response. Chignalia AZ, Vogel SM, Reynolds AB, Mehta D, Dull RO, Minshall RD, Malik AB, Liu Y (2015) Am J Pathol 185:1251-63 | 2015 |
| Phage-display-guided nanocarrier targeting to atheroprone vasculature. Hofmeister LH, Lee SH, Norlander AE, Montaniel KR, Chen W, Harrison DG, Sung HJ (2015) ACS Nano 9:4435-46 | 2015 |
| Inflammation, immunity, and hypertensive end-organ damage. McMaster WG, Kirabo A, Madhur MS, Harrison DG (2015) Circ Res 116:1022-33 | 2015 |
| Computational and functional analyses of a small-molecule binding site in ROMK. Swale DR, Sheehan JH, Banerjee S, Husni AS, Nguyen TT, Meiler J, Denton JS (2015) Biophys J 108:1094-103 | 2015 |
| Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells. Neelisetty S, Alford C, Reynolds K, Woodbury L, Nlandu-Khodo S, Yang H, Fogo AB, Hao CM, Harris RC, Zent R, Gewin L (2015) Kidney Int 88:503-14 | 2015 |
| Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts. Guo L, Chen Z, Amarnath V, Yancey PG, Van Lenten BJ, Savage JR, Fazio S, Linton MF, Davies SS (2015) Antioxid Redox Signal 22:1633-45 | 2015 |
| KIM-1-mediated phagocytosis reduces acute injury to the kidney. Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV (2015) J Clin Invest 125:1620-36 | 2015 |
| Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili. Floyd KA, Moore JL, Eberly AR, Good JA, Shaffer CL, Zaver H, Almqvist F, Skaar EP, Caprioli RM, Hadjifrangiskou M (2015) PLoS Pathog 11:e1004697 | 2015 |
| Biophysical characterization of interactions between the C-termini of peripheral nerve claudins and the PDZ₁ domain of zonula occludens. Wu J, Peng D, Zhang Y, Lu Z, Voehler M, Sanders CR, Li J (2015) Biochem Biophys Res Commun 459:87-93 | 2015 |
| Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapping. Van de Plas R, Yang J, Spraggins J, Caprioli RM (2015) Nat Methods 12:366-72 | 2015 |
| Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors. Ning B, Feldkamp MD, Cortez D, Chazin WJ, Friedman KL, Fanning E (2015) PLoS One 10:e0116093 | 2015 |
| Diphenylpyrazoles as replication protein a inhibitors. Waterson AG, Kennedy JP, Patrone JD, Pelz NF, Feldkamp MD, Frank AO, Vangamudi B, Souza-Fagundes EM, Rossanese OW, Chazin WJ, Fesik SW (2015) ACS Med Chem Lett 6:140-5 | 2015 |
| Cellular oxidative stress response mediates radiosensitivity in Fus1-deficient mice. Yazlovitskaya EM, Voziyan PA, Manavalan T, Yarbrough WG, Ivanova AV (2015) Cell Death Dis 6:e1652 | 2015 |
| Interleukin-5 facilitates lung metastasis by modulating the immune microenvironment. Zaynagetdinov R, Sherrill TP, Gleaves LA, McLoed AG, Saxon JA, Habermann AC, Connelly L, Dulek D, Peebles RS, Fingleton B, Yull FE, Stathopoulos GT, Blackwell TS (2015) Cancer Res 75:1624-1634 | 2015 |
| Evidence for a novel functional role of astrocytes in the acute homeostatic response to high-fat diet intake in mice. Buckman LB, Thompson MM, Lippert RN, Blackwell TS, Yull FE, Ellacott KL (2015) Mol Metab 4:58-63 | 2015 |
| Yersinia enterocolitica exploits different pathways to accomplish adhesion and toxin injection into host cells. Keller B, Mühlenkamp M, Deuschle E, Siegfried A, Mössner S, Schade J, Griesinger T, Katava N, Braunsdorf C, Fehrenbacher B, Jiménez-Soto LF, Schaller M, Haas R, Genth H, Retta SF, Meyer H, Böttcher RT, Zent R, Schütz M, Autenrieth IB, Bohn E (2015) Cell Microbiol 17:1179-204 | 2015 |
| Tissue protein imaging at 1 μm laser spot diameter for high spatial resolution and high imaging speed using transmission geometry MALDI TOF MS. Zavalin A, Yang J, Hayden K, Vestal M, Caprioli RM (2015) Anal Bioanal Chem 407:2337-42 | 2015 |
| EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling. Lu A, Zuo C, He Y, Chen G, Piao L, Zhang J, Xiao B, Shen Y, Tang J, Kong D, Alberti S, Chen D, Zuo S, Zhang Q, Yan S, Fei X, Yuan F, Zhou B, Duan S, Yu Y, Lazarus M, Su Y, Breyer RM, Funk CD, Yu Y (2015) J Clin Invest 125:1228-42 | 2015 |
| Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. Saleh MA, McMaster WG, Wu J, Norlander AE, Funt SA, Thabet SR, Kirabo A, Xiao L, Chen W, Itani HA, Michell D, Huan T, Zhang Y, Takaki S, Titze J, Levy D, Harrison DG, Madhur MS (2015) J Clin Invest 125:1189-202 | 2015 |
| Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress. Tanjore H, Cheng DS, Degryse AL, Zoz DF, Abdolrasulnia R, Lawson WE, Blackwell TS (2015) J Biol Chem 290:3277 | 2015 |
| TIM-1 signaling is required for maintenance and induction of regulatory B cells. Yeung MY, Ding Q, Brooks CR, Xiao S, Workman CJ, Vignali DA, Ueno T, Padera RF, Kuchroo VK, Najafian N, Rothstein DM (2015) Am J Transplant 15:942-53 | 2015 |
| A case of subepidermal blistering disease with autoantibodies to multiple laminin subunits who developed later autoantibodies to alpha-5 chain of type IV collagen associated with membranous glomerulonephropathy. Sueki H, Sato Y, Ohtoshi S, Nakada T, Yoshimura A, Tateishi C, Borza DB, Fader W, Ghohestani RF, Hirako Y, Koga H, Ishii N, Tsuchisaka A, Qian H, Li X, Hashimoto T (2015) Acta Derm Venereol 95:826-9 | 2015 |
| Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine. Szulik MW, Pallan PS, Nocek B, Voehler M, Banerjee S, Brooks S, Joachimiak A, Egli M, Eichman BF, Stone MP (2015) Biochemistry 54:1294-305 | 2015 |
| Automated analysis of cell-matrix adhesions in 2D and 3D environments. Broussard JA, Diggins NL, Hummel S, Georgescu W, Quaranta V, Webb DJ (2015) Sci Rep 5:8124 | 2015 |
| TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. Shaw AK, Pickup MW, Chytil A, Aakre M, Owens P, Moses HL, Novitskiy SV (2015) PLoS One 10:e0117908 | 2015 |
| Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells. Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K (2015) Stem Cell Reports 4:297-311 | 2015 |
| RNA-Seq reveals a role for NFAT-signaling in human retinal microvascular endothelial cells treated with TNFα. Savage SR, Bretz CA, Penn JS (2015) PLoS One 10:e0116941 | 2015 |
| The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites. Karaköse E, Geiger T, Flynn K, Lorenz-Baath K, Zent R, Mann M, Fässler R (2015) J Cell Sci 128:1023-33 | 2015 |
| Rare variants in RTEL1 are associated with familial interstitial pneumonia. Cogan JD, Kropski JA, Zhao M, Mitchell DB, Rives L, Markin C, Garnett ET, Montgomery KH, Mason WR, McKean DF, Powers J, Murphy E, Olson LM, Choi L, Cheng DS, Blue EM, Young LR, Lancaster LH, Steele MP, Brown KK, Schwarz MI, Fingerlin TE, Schwartz DA, Lawson WE, Loyd JE, Zhao Z, Phillips JA, Blackwell TS (2015) Am J Respir Crit Care Med 191:646-55 | 2015 |
| Hypohalous acids contribute to renal extracellular matrix damage in experimental diabetes. Brown KL, Darris C, Rose KL, Sanchez OA, Madu H, Avance J, Brooks N, Zhang MZ, Fogo A, Harris R, Hudson BG, Voziyan P (2015) Diabetes 64:2242-53 | 2015 |
| CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Palubinsky AM, Stankowski JN, Kale AC, Codreanu SG, Singer RJ, Liebler DC, Stanwood GD, McLaughlin B (2015) Antioxid Redox Signal 23:535-49 | 2015 |
| Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice. Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA (2015) Hypertension 65:569-76 | 2015 |
| Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation. Frick PL, Paudel BB, Tyson DR, Quaranta V (2015) J Cell Physiol 230:1403-12 | 2015 |
| Histology-directed and imaging mass spectrometry: An emerging technology in ectopic calcification. Taverna D, Boraldi F, De Santis G, Caprioli RM, Quaglino D (2015) Bone 74:83-94 | 2015 |
| Antihypertensive mechanisms of intra-renal dopamine. Zhang MZ, Harris RC (2015) Curr Opin Nephrol Hypertens 24:117-22 | 2015 |
| Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. Williams AS, Kang L, Zheng J, Grueter C, Bracy DP, James FD, Pozzi A, Wasserman DH (2015) J Biol Chem 290:6546-57 | 2015 |
| Toward a science of tumor forecasting for clinical oncology. Yankeelov TE, Quaranta V, Evans KJ, Rericha EC (2015) Cancer Res 75:918-23 | 2015 |
| Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells. Canfield K, Li J, Wilkins OM, Morrison MM, Ung M, Wells W, Williams CR, Liby KT, Vullhorst D, Buonanno A, Hu H, Schiff R, Cook RS, Kurokawa M (2015) Cell Cycle 14:648-55 | 2015 |
| Polyacrylamide gels for invadopodia and traction force assays on cancer cells. Jerrell RJ, Parekh A (2015) J Vis Exp :52343 | 2015 |
| Annotation of human cancers with EGFR signaling-associated protein complexes using proximity ligation assays. Smith MA, Hall R, Fisher K, Haake SM, Khalil F, Schabath MB, Vuaroqueaux V, Fiebig HH, Altiok S, Chen YA, Haura EB (2015) Sci Signal 8:ra4 | 2015 |
| Biology coming full circle: joining the whole and the parts. Wikswo JP, Porter AP (2015) Exp Biol Med (Maywood) 240:3-7 | 2015 |
| Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation. Xiao S, Brooks CR, Sobel RA, Kuchroo VK (2015) J Immunol 194:1602-8 | 2015 |
| Effects of particle size and porosity on in vivo remodeling of settable allograft bone/polymer composites. Prieto EM, Talley AD, Gould NR, Zienkiewicz KJ, Drapeau SJ, Kalpakci KN, Guelcher SA (2015) J Biomed Mater Res B Appl Biomater 103:1641-51 | 2015 |
| CASP10-BCL::Fold efficiently samples topologies of large proteins. Heinze S, Putnam DK, Fischer AW, Kohlmann T, Weiner BE, Meiler J (2015) Proteins 83:547-63 | 2015 |
| p47(phox) contributes to albuminuria and kidney fibrosis in mice. Wang H, Chen X, Su Y, Paueksakon P, Hu W, Zhang MZ, Harris RC, Blackwell TS, Zent R, Pozzi A (2015) Kidney Int 87:948-62 | 2015 |
| The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes. Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P, Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O' Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E, Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M, Doxsey S, Jackson A, Stupka E, Winey M, Beales PL (2015) J Med Genet 52:147-56 | 2015 |
| Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease. Levic DS, Minkel JR, Wang WD, Rybski WM, Melville DB, Knapik EW (2015) J Mol Med (Berl) 93:165-76 | 2015 |
| Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins. Guilliam TA, Jozwiakowski SK, Ehlinger A, Barnes RP, Rudd SG, Bailey LJ, Skehel JM, Eckert KA, Chazin WJ, Doherty AJ (2015) Nucleic Acids Res 43:1056-68 | 2015 |
| Heterogeneity in vascular smooth muscle cell embryonic origin in relation to adult structure, physiology, and disease. Pfaltzgraff ER, Bader DM (2015) Dev Dyn 244:410-6 | 2015 |
| Arrestins regulate cell spreading and motility via focal adhesion dynamics. Cleghorn WM, Branch KM, Kook S, Arnette C, Bulus N, Zent R, Kaverina I, Gurevich EV, Weaver AM, Gurevich VV (2015) Mol Biol Cell 26:622-35 | 2015 |
| Enhanced Performance of Plasmid DNA Polyplexes Stabilized by a Combination of Core Hydrophobicity and Surface PEGylation. Adolph EJ, Nelson CE, Werfel TA, Guo R, Davidson JM, Guelcher SA, Duvall CL (2014) J Mater Chem B 2:8154-8164 | 2014 |
| p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD (2015) Dev Biol 399:41-53 | 2015 |
| Genetic analysis of the localization of APOBEC3F to human immunodeficiency virus type 1 virion cores. Donahue JP, Levinson RT, Sheehan JH, Sutton L, Taylor HE, Meiler J, D'Aquila RT, Song C (2015) J Virol 89:2415-24 | 2015 |
| Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells. Nakamura T, Shinriki S, Jono H, Guo J, Ueda M, Hayashi M, Yamashita S, Zijlstra A, Nakayama H, Hiraki A, Shinohara M, Ando Y (2015) Oncotarget 6:1008-19 | 2015 |
| Alterations of urinary metabolite profile in model diabetic nephropathy. Stec DF, Wang S, Stothers C, Avance J, Denson D, Harris R, Voziyan P (2015) Biochem Biophys Res Commun 456:610-4 | 2015 |
| Imaging mass spectrometry for assessing cutaneous wound healing: analysis of pressure ulcers. Taverna D, Pollins AC, Sindona G, Caprioli RM, Nanney LB (2015) J Proteome Res 14:986-96 | 2015 |
| Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells. Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT (2015) J Mol Cell Cardiol 79:295-302 | 2015 |
| Histology-directed microwave assisted enzymatic protein digestion for MALDI MS analysis of mammalian tissue. Taverna D, Norris JL, Caprioli RM (2015) Anal Chem 87:670-6 | 2015 |
| Shaping the intestinal brush border. Crawley SW, Mooseker MS, Tyska MJ (2014) J Cell Biol 207:441-51 | 2014 |
| Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS (2015) J Clin Invest 125:141-56 | 2015 |
| α2β1 integrin, GPVI receptor, and common FcRγ chain on mouse platelets mediate distinct responses to collagen in models of thrombosis. Marjoram RJ, Li Z, He L, Tollefsen DM, Kunicki TJ, Dickeson SK, Santoro SA, Zutter MM (2014) PLoS One 9:e114035 | 2014 |
| Towards automated discrimination of lipids versus peptides from full scan mass spectra. Dittwald P, Nghia VT, Harris GA, Caprioli RM, Van de Plas R, Laukens K, Gambin A, Valkenborg D (2014) EuPA Open Proteom 4:87-100 | 2014 |
| Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ. Suarez S, McCollum GW, Bretz CA, Yang R, Capozzi ME, Penn JS (2014) Invest Ophthalmol Vis Sci 55:8232-40 | 2014 |
| Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells. Vilgelm AE, Pawlikowski JS, Liu Y, Hawkins OE, Davis TA, Smith J, Weller KP, Horton LW, McClain CM, Ayers GD, Turner DC, Essaka DC, Stewart CF, Sosman JA, Kelley MC, Ecsedy JA, Johnston JN, Richmond A (2015) Cancer Res 75:181-93 | 2015 |
| Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization. Plosa EJ, Young LR, Gulleman PM, Polosukhin VV, Zaynagetdinov R, Benjamin JT, Im AM, van der Meer R, Gleaves LA, Bulus N, Han W, Prince LS, Blackwell TS, Zent R (2014) Development 141:4751-62 | 2014 |
| Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. Kropski JA, Pritchett JM, Zoz DF, Crossno PF, Markin C, Garnett ET, Degryse AL, Mitchell DB, Polosukhin VV, Rickman OB, Choi L, Cheng DS, McConaha ME, Jones BR, Gleaves LA, McMahon FB, Worrell JA, Solus JF, Ware LB, Lee JW, Massion PP, Zaynagetdinov R, White ES, Kurtis JD, Johnson JE, Groshong SD, Lancaster LH, Young LR, Steele MP, Phillips Iii JA, Cogan JD, Loyd JE, Lawson WE, Blackwell TS (2015) Am J Respir Crit Care Med 191:417-26 | 2015 |
| Analysis of nidogen-1/laminin γ1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes. Lössl P, Kölbel K, Tänzler D, Nannemann D, Ihling CH, Keller MV, Schneider M, Zaucke F, Meiler J, Sinz A (2014) PLoS One 9:e112886 | 2014 |
| CD148 tyrosine phosphatase promotes cadherin cell adhesion. Takahashi K, Matafonov A, Sumarriva K, Ito H, Lauhan C, Zemel D, Tsuboi N, Chen J, Reynolds A, Takahashi T (2014) PLoS One 9:e112753 | 2014 |
| A three-dimensional computational model of collagen network mechanics. Lee B, Zhou X, Riching K, Eliceiri KW, Keely PJ, Guelcher SA, Weaver AM, Jiang Y (2014) PLoS One 9:e111896 | 2014 |
| Engineered three-dimensional microfluidic device for interrogating cell-cell interactions in the tumor microenvironment. Hockemeyer K, Janetopoulos C, Terekhov A, Hofmeister W, Vilgelm A, Costa L, Wikswo JP, Richmond A (2014) Biomicrofluidics 8:044105 | 2014 |
| Molecular imaging of folate receptor β-positive macrophages during acute lung inflammation. Han W, Zaynagetdinov R, Yull FE, Polosukhin VV, Gleaves LA, Tanjore H, Young LR, Peterson TE, Manning HC, Prince LS, Blackwell TS (2015) Am J Respir Cell Mol Biol 53:50-9 | 2015 |
| Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. Brown JA, Sherrod SD, Goodwin CR, Brewer B, Yang L, Garbett KA, Li D, McLean JA, Wikswo JP, Mirnics K (2014) J Neuroinflammation 11:183 | 2014 |
| GTP cyclohydrolase I gene polymorphisms are associated with endothelial dysfunction and oxidative stress in patients with type 2 diabetes mellitus. Wolkow PP, Kosiniak-Kamysz W, Osmenda G, Wilk G, Bujak-Gizycka B, Ignacak A, Kanitkar M, Walus-Miarka M, Harrison DG, Korbut R, Malecki MT, Guzik TJ (2014) PLoS One 9:e108587 | 2014 |
| Metastasis as a therapeutic target in prostate cancer: a conceptual framework. Stoletov K, Bond D, Hebron K, Raha S, Zijlstra A, Lewis JD (2014) Am J Clin Exp Urol 2:45-56 | 2014 |
| Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer. Johnson RW, Merkel AR, Page JM, Ruppender NS, Guelcher SA, Sterling JA (2014) Clin Exp Metastasis 31:945-59 | 2014 |
| The arginine decarboxylase pathways of host and pathogen interact to impact inflammatory pathways in the lung. Paulson NB, Gilbertsen AJ, Dalluge JJ, Welchlin CW, Hughes J, Han W, Blackwell TS, Laguna TA, Williams BJ (2014) PLoS One 9:e111441 | 2014 |
| Cellular manganese content is developmentally regulated in human dopaminergic neurons. Kumar KK, Lowe EW, Aboud AA, Neely MD, Redha R, Bauer JA, Odak M, Weaver CD, Meiler J, Aschner M, Bowman AB (2014) Sci Rep 4:6801 | 2014 |
| Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response. Yang J, Hawkins OE, Barham W, Gilchuk P, Boothby M, Ayers GD, Joyce S, Karin M, Yull FE, Richmond A (2014) Cancer Res 74:7274-84 | 2014 |
| Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension. Nozik-Grayck E, Woods C, Taylor JM, Benninger RK, Johnson RD, Villegas LR, Stenmark KR, Harrison DG, Majka SM, Irwin D, Farrow KN (2014) Am J Physiol Lung Cell Mol Physiol 307:L868-76 | 2014 |
| Overelaborated synaptic architecture and reduced synaptomatrix glycosylation in a Drosophila classic galactosemia disease model. Jumbo-Lucioni P, Parkinson W, Broadie K (2014) Dis Model Mech 7:1365-78 | 2014 |
| Detection of internal exon deletion with exon Del. Guo Y, Zhao S, Lehmann BD, Sheng Q, Shaver TM, Stricker TP, Pietenpol JA, Shyr Y (2014) BMC Bioinformatics 15:332 | 2014 |
| Biodegradable lysine-derived polyurethane scaffolds promote healing in a porcine full-thickness excisional wound model. Adolph EJ, Pollins AC, Cardwell NL, Davidson JM, Guelcher SA, Nanney LB (2014) J Biomater Sci Polym Ed 25:1973-85 | 2014 |
| KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Koh DI, Han D, Ryu H, Choi WI, Jeon BN, Kim MK, Kim Y, Kim JY, Parry L, Clarke AR, Reynolds AB, Hur MW (2014) Proc Natl Acad Sci U S A 111:15078-83 | 2014 |
| Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery. Kothiwale S, Borza CM, Lowe EW, Pozzi A, Meiler J (2015) Drug Discov Today 20:255-61 | 2015 |
| Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis. Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL (2014) Breast Cancer Res 16:425 | 2014 |
| A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation. Wang X, Page-McCaw A (2014) J Cell Biol 206:923-36 | 2014 |
| Oligoclonal CD8+ T cells play a critical role in the development of hypertension. Trott DW, Thabet SR, Kirabo A, Saleh MA, Itani H, Norlander AE, Wu J, Goldstein A, Arendshorst WJ, Madhur MS, Chen W, Li CI, Shyr Y, Harrison DG (2014) Hypertension 64:1108-15 | 2014 |
| Two protein N-acetylgalactosaminyl transferases regulate synaptic plasticity by activity-dependent regulation of integrin signaling. Dani N, Zhu H, Broadie K (2014) J Neurosci 34:13047-65 | 2014 |
| Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution. Stanford JC, Young C, Hicks D, Owens P, Williams A, Vaught DB, Morrison MM, Lim J, Williams M, Brantley-Sieders DM, Balko JM, Tonetti D, Earp HS, Cook RS (2014) J Clin Invest 124:4737-52 | 2014 |
| DC isoketal-modified proteins activate T cells and promote hypertension. Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, Shen XZ, Shyr Y, Chen SC, Mernaugh RL, Laffer CL, Elijovich F, Davies SS, Moreno H, Madhur MS, Roberts J, Harrison DG (2014) J Clin Invest 124:4642-56 | 2014 |
| The homology model of PMP22 suggests mutations resulting in peripheral neuropathy disrupt transmembrane helix packing. Mittendorf KF, Kroncke BM, Meiler J, Sanders CR (2014) Biochemistry 53:6139-41 | 2014 |
| Multichamber Multipotentiostat System for Cellular Microphysiometry. Lima EA, Snider RM, Reiserer RS, McKenzie JR, Kimmel DW, Eklund SE, Wikswo JP, Cliffel DE (2014) Sens Actuators B Chem 204:536-543 | 2014 |
| Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma. Andl T, Le Bras GF, Richards NF, Allison GL, Loomans HA, Washington MK, Revetta F, Lee RK, Taylor C, Moses HL, Andl CD (2014) Carcinogenesis 35:2602-10 | 2014 |
| Isolation and physiological analysis of mouse cardiomyocytes. Roth GM, Bader DM, Pfaltzgraff ER (2014) J Vis Exp :e51109 | 2014 |
| BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation. Pickup MW, Hover LD, Polikowsky ER, Chytil A, Gorska AE, Novitskiy SV, Moses HL, Owens P (2015) Mol Oncol 9:179-91 | 2015 |
| The relevance and potential roles of microphysiological systems in biology and medicine. Wikswo JP (2014) Exp Biol Med (Maywood) 239:1061-72 | 2014 |
| EGF receptor deletion in podocytes attenuates diabetic nephropathy. Chen J, Chen JK, Harris RC (2015) J Am Soc Nephrol 26:1115-25 | 2015 |
| Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders. Conn PJ, Lindsley CW, Meiler J, Niswender CM (2014) Nat Rev Drug Discov 13:692-708 | 2014 |
| Endoglin promotes angiogenesis in cell- and animal-based models of retinal neovascularization. Barnett JM, Suarez S, McCollum GW, Penn JS (2014) Invest Ophthalmol Vis Sci 55:6490-8 | 2014 |
| Position and length of fatty acids strongly affect receptor selectivity pattern of human pancreatic polypeptide analogues. Mäde V, Bellmann-Sickert K, Kaiser A, Meiler J, Beck-Sickinger AG (2014) ChemMedChem 9:2463-74 | 2014 |
| Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels. Zachman AL, Wang X, Tucker-Schwartz JM, Fitzpatrick ST, Lee SH, Guelcher SA, Skala MC, Sung HJ (2014) Biomaterials 35:9635-48 | 2014 |
| Automated anatomical interpretation of ion distributions in tissue: linking imaging mass spectrometry to curated atlases. Verbeeck N, Yang J, De Moor B, Caprioli RM, Waelkens E, Van de Plas R (2014) Anal Chem 86:8974-82 | 2014 |
| Basic science: Pathophysiology: oxidative stress. Harrison DG (2014) J Am Soc Hypertens 8:601-3 | 2014 |
| Role of TGF-β signaling in generation of CD39+CD73+ myeloid cells in tumors. Ryzhov SV, Pickup MW, Chytil A, Gorska AE, Zhang Q, Owens P, Feoktistov I, Moses HL, Novitskiy SV (2014) J Immunol 193:3155-64 | 2014 |
| ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Marriott S, Baskir RS, Gaskill C, Menon S, Carrier EJ, Williams J, Talati M, Helm K, Alford CE, Kropski JA, Loyd J, Wheeler L, Johnson J, Austin E, Nozik-Grayck E, Meyrick B, West JD, Klemm DJ, Majka SM (2014) Am J Physiol Cell Physiol 307:C684-98 | 2014 |
| Glutathione S-transferase M1 modulates allergen-induced NF-κB activation in asthmatic airway epithelium. Polosukhin VV, Polosukhin IV, Hoskins A, Han W, Abdolrasulnia R, Blackwell TS, Dworski R (2014) Allergy 69:1666-72 | 2014 |
| PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors. Lehmann BD, Bauer JA, Schafer JM, Pendleton CS, Tang L, Johnson KC, Chen X, Balko JM, Gómez H, Arteaga CL, Mills GB, Sanders ME, Pietenpol JA (2014) Breast Cancer Res 16:406 | 2014 |
| Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer. Walsh AJ, Cook RS, Sanders ME, Aurisicchio L, Ciliberto G, Arteaga CL, Skala MC (2014) Cancer Res 74:5184-94 | 2014 |
| Longitudinal assessment of mouse renal injury using high-resolution anatomic and magnetization transfer MR imaging. Wang F, Jiang R, Takahashi K, Gore J, Harris RC, Takahashi T, Quarles CC (2014) Magn Reson Imaging 32:1125-32 | 2014 |
| Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g. Gérard A, Patino-Lopez G, Beemiller P, Nambiar R, Ben-Aissa K, Liu Y, Totah FJ, Tyska MJ, Shaw S, Krummel MF (2014) Cell 158:492-505 | 2014 |
| Dynamics of brush border remodeling induced by enteropathogenic E. coli. Shifrin DA, Crawley SW, Grega-Larson NE, Tyska MJ (2014) Gut Microbes 5:504-16 | 2014 |
| In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts. McCormack DR, Walsh AJ, Sit W, Arteaga CL, Chen J, Cook RS, Skala MC (2014) Biomed Opt Express 5:2247-61 | 2014 |
| Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy. Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A (2015) J Am Soc Nephrol 26:597-610 | 2015 |
| Guanylate Cyclase-Activating Protein-2 Undergoes Structural Changes upon Binding to Detergent Micelles and Bicelles. Margetić A, Nannemann D, Meiler J, Huster D, Theisgen S (2014) Biochim Biophys Acta 1838:2767-77 | 2014 |
| A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry. Manier ML, Spraggins JM, Reyzer ML, Norris JL, Caprioli RM (2014) J Mass Spectrom 49:665-73 | 2014 |
| Subtyping of triple-negative breast cancer: implications for therapy. Abramson VG, Lehmann BD, Ballinger TJ, Pietenpol JA (2015) Cancer 121:8-16 | 2015 |
| p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. Lang RA, Herman K, Reynolds AB, Hildebrand JD, Plageman TF (2014) Development 141:3177-87 | 2014 |
| A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit. Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE (2014) J Biol Chem 289:24475-87 | 2014 |
| α2β1 Integrin. Madamanchi A, Santoro SA, Zutter MM (2014) Adv Exp Med Biol 819:41-60 | 2014 |
| Differential role for p120-catenin in regulation of TLR4 signaling in macrophages. Yang Z, Sun D, Yan Z, Reynolds AB, Christman JW, Minshall RD, Malik AB, Zhang Y, Hu G (2014) J Immunol 193:1931-41 | 2014 |
| DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia. Markham NO, Doll CA, Dohn MR, Miller RK, Yu H, Coffey RJ, McCrea PD, Gamse JT, Reynolds AB (2014) Mol Biol Cell 25:2592-603 | 2014 |
| Supramolecular organization of the α121-α565 collagen IV network. Robertson WE, Rose KL, Hudson BG, Vanacore RM (2014) J Biol Chem 289:25601-10 | 2014 |
| Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis. Fioret BA, Heimfeld JD, Paik DT, Hatzopoulos AK (2014) Cell Rep 8:229-41 | 2014 |
| Inhibition of BMP signaling suppresses metastasis in mammary cancer. Owens P, Pickup MW, Novitskiy SV, Giltnane JM, Gorska AE, Hopkins CR, Hong CC, Moses HL (2015) Oncogene 34:2437-49 | 2015 |
| Advanced mass spectrometry technologies for the study of microbial pathogenesis. Moore JL, Caprioli RM, Skaar EP (2014) Curr Opin Microbiol 19:45-51 | 2014 |
| Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer. Jovanović B, Beeler JS, Pickup MW, Chytil A, Gorska AE, Ashby WJ, Lehmann BD, Zijlstra A, Pietenpol JA, Moses HL (2014) Breast Cancer Res 16:R69 | 2014 |
| Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. Chen X, Wang H, Liao HJ, Hu W, Gewin L, Mernaugh G, Zhang S, Zhang ZY, Vega-Montoto L, Vanacore RM, Fässler R, Zent R, Pozzi A (2014) J Clin Invest 124:3295-310 | 2014 |
| IκB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm. Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS (2014) J Immunol 193:1184-93 | 2014 |
| Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity. Chen Z, Guo L, Zhang Y, Walzem RL, Pendergast JS, Printz RL, Morris LC, Matafonova E, Stien X, Kang L, Coulon D, McGuinness OP, Niswender KD, Davies SS (2014) J Clin Invest 124:3391-406 | 2014 |
| Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Dulek DE, Newcomb DC, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill TP, Blackwell TS, Moore ML, Boyd KL, Kolls JK, Peebles RS (2014) Infect Immun 82:3723-39 | 2014 |
| Apical vesicle trafficking takes center stage in neonatal enteropathies. Knowles BC, Tyska MJ, Goldenring JR (2014) Gastroenterology 147:15-7 | 2014 |
| IgG4-restricted anti-glomerular basement membrane autoantibodies targeting quaternary epitopes of native α345(IV) collagen. Borza DB (2014) Am J Kidney Dis 64:156-7 | 2014 |
| A newly discovered TSHR variant (L665F) associated with nonautoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 and TM7. Jaeschke H, Schaarschmidt J, Eszlinger M, Huth S, Puttinger R, Rittinger O, Meiler J, Paschke R (2014) J Clin Endocrinol Metab 99:E2051-9 | 2014 |
| Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells. Miller CG, Pozzi A, Zent R, Schwarzbauer JE (2014) Mol Biol Cell 25:2342-50 | 2014 |
| Derivation and experimental comparison of cell-division probability densities. Leander R, Allen EJ, Garbett SP, Tyson DR, Quaranta V (2014) J Theor Biol 359:129-35 | 2014 |
| The role of cytochrome P450 epoxygenases in retinal angiogenesis. Capozzi ME, McCollum GW, Penn JS (2014) Invest Ophthalmol Vis Sci 55:4253-60 | 2014 |
| Mitigation of oxygen-induced retinopathy in α2β1 integrin-deficient mice. Madamanchi A, Capozzi M, Geng L, Li Z, Friedman RD, Dickeson SK, Penn JS, Zutter MM (2014) Invest Ophthalmol Vis Sci 55:4338-47 | 2014 |
| Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture. McCall AS, Cummings CF, Bhave G, Vanacore R, Page-McCaw A, Hudson BG (2014) Cell 157:1380-92 | 2014 |
| Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems. Marasco CC, Goodwin CR, Winder DG, Schramm-Sapyta NL, McLean JA, Wikswo JP (2014) Exp Biol Med (Maywood) 239:1433-42 | 2014 |
| Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease. Knowles BC, Roland JT, Krishnan M, Tyska MJ, Lapierre LA, Dickman PS, Goldenring JR, Shub MD (2014) J Clin Invest 124:2947-62 | 2014 |
| Phase II trial of bortezomib plus doxorubicin in hepatocellular carcinoma (E6202): a trial of the Eastern Cooperative Oncology Group. Ciombor KK, Feng Y, Benson AB, Su Y, Horton L, Short SP, Kauh JS, Staley C, Mulcahy M, Powell M, Amiri KI, Richmond A, Berlin J (2014) Invest New Drugs 32:1017-27 | 2014 |
| Pyruvate formate-lyase interacts directly with the formate channel FocA to regulate formate translocation. Doberenz C, Zorn M, Falke D, Nannemann D, Hunger D, Beyer L, Ihling CH, Meiler J, Sinz A, Sawers RG (2014) J Mol Biol 426:2827-39 | 2014 |
| The microfluidic multitrap nanophysiometer for hematologic cancer cell characterization reveals temporal sensitivity of the calcein-AM efflux assay. Byrd TF, Hoang LT, Kim EG, Pfister ME, Werner EM, Arndt SE, Chamberlain JW, Hughey JJ, Nguyen BA, Schneibel EJ, Wertz LL, Whitfield JS, Wikswo JP, Seale KT (2014) Sci Rep 4:5117 | 2014 |
| Techniques and assays for the study of angiogenesis. Irvin MW, Zijlstra A, Wikswo JP, Pozzi A (2014) Exp Biol Med (Maywood) 239:1476-88 | 2014 |
| Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension. West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, Hong CC, Meyrick B, Loyd JE, Bowman AB, Ess KC, Klemm DJ, Young PP, Merryman WD, Kotton D, Majka SM (2014) Am J Physiol Cell Physiol 307:C415-30 | 2014 |
| Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles. Grove KJ, Voziyan PA, Spraggins JM, Wang S, Paueksakon P, Harris RC, Hudson BG, Caprioli RM (2014) J Lipid Res 55:1375-85 | 2014 |
| Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R (2014) Cancer Cell 25:719-34 | 2014 |
| Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. Goodwin CR, Sherrod SD, Marasco CC, Bachmann BO, Schramm-Sapyta N, Wikswo JP, McLean JA (2014) Anal Chem 86:6563-71 | 2014 |
| A structure-specific nucleic acid-binding domain conserved among DNA repair proteins. Mason AC, Rambo RP, Greer B, Pritchett M, Tainer JA, Cortez D, Eichman BF (2014) Proc Natl Acad Sci U S A 111:7618-23 | 2014 |
| In silico analysis and experimental verification of OSR1 kinase - Peptide interaction. Austin TM, Nannemann DP, Deluca SL, Meiler J, Delpire E (2014) J Struct Biol 187:58-65 | 2014 |
| Acyl-coenzyme A-binding protein regulates Beta-oxidation required for growth and survival of non-small cell lung cancer. Harris FT, Rahman SM, Hassanein M, Qian J, Hoeksema MD, Chen H, Eisenberg R, Chaurand P, Caprioli RM, Shiota M, Massion PP (2014) Cancer Prev Res (Phila) 7:748-57 | 2014 |
| High resolution MALDI imaging mass spectrometry of retinal tissue lipids. Anderson DM, Ablonczy Z, Koutalos Y, Spraggins J, Crouch RK, Caprioli RM, Schey KL (2014) J Am Soc Mass Spectrom 25:1394-403 | 2014 |
| Matrix pre-coated targets for high throughput MALDI imaging of proteins. Yang J, Caprioli RM (2014) J Mass Spectrom 49:417-22 | 2014 |
| Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury. Kapitsinou PP, Sano H, Michael M, Kobayashi H, Davidoff O, Bian A, Yao B, Zhang MZ, Harris RC, Duffy KJ, Erickson-Miller CL, Sutton TA, Haase VH (2014) J Clin Invest 124:2396-409 | 2014 |
| Endothelial progenitor cells augment collateralization and hemodynamic rescue in a model of chronic cerebral ischemia. Hecht N, Schneider UC, Czabanka M, Vinci M, Hatzopoulos AK, Vajkoczy P, Woitzik J (2014) J Cereb Blood Flow Metab 34:1297-305 | 2014 |
| Resident progenitors, not exogenous migratory cells, generate the majority of visceral mesothelium in organogenesis. Winters NI, Williams AM, Bader DM (2014) Dev Biol 391:125-32 | 2014 |
| Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1. Feldkamp MD, Mason AC, Eichman BF, Chazin WJ (2014) Biochemistry 53:3052-61 | 2014 |
| Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion. Crawley SW, Shifrin DA, Grega-Larson NE, McConnell RE, Benesh AE, Mao S, Zheng Y, Zheng QY, Nam KT, Millis BA, Kachar B, Tyska MJ (2014) Cell 157:433-446 | 2014 |
| Renal endothelial dysfunction in diabetic nephropathy. Cheng H, Harris RC (2014) Cardiovasc Hematol Disord Drug Targets 14:22-33 | 2014 |
| Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC. Amato KR, Wang S, Hastings AK, Youngblood VM, Santapuram PR, Chen H, Cates JM, Colvin DC, Ye F, Brantley-Sieders DM, Cook RS, Tan L, Gray NS, Chen J (2014) J Clin Invest 124:2037-49 | 2014 |
| BMP pathway regulation of and by macrophages. Talati M, West J, Zaynagetdinov R, Hong CC, Han W, Blackwell T, Robinson L, Blackwell TS, Lane K (2014) PLoS One 9:e94119 | 2014 |
| Interplay between base excision repair activity and toxicity of 3-methyladenine DNA glycosylases in an E. coli complementation system. Troll CJ, Adhikary S, Cueff M, Mitra I, Eichman BF, Camps M (2014) Mutat Res 763-764:64-73 | 2014 |
| Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy. Zhang MZ, Wang Y, Paueksakon P, Harris RC (2014) Diabetes 63:2063-72 | 2014 |
| Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids. Davies SS, Guo L (2014) Chem Phys Lipids 181:1-33 | 2014 |
| Multi-perspective quality control of Illumina exome sequencing data using QC3. Guo Y, Zhao S, Sheng Q, Ye F, Li J, Lehmann B, Pietenpol J, Samuels DC, Shyr Y (2014) Genomics 103:323-8 | 2014 |
| Beyond genetics in personalized cancer treatment: assessing dynamics and heterogeneity of tumor responses. Tyson DR, Quaranta V (2013) Per Med 10:221-225 | 2013 |
| Pro32Pro33 mutations in the integrin β3 PSI domain result in αIIbβ3 priming and enhanced adhesion: reversal of the hypercoagulability phenotype by the Src inhibitor SKI-606. Oliver KH, Jessen T, Crawford EL, Chung CY, Sutcliffe JS, Carneiro AM (2014) Mol Pharmacol 85:921-31 | 2014 |
| Implementation of a Gaussian beam laser and aspheric optics for high spatial resolution MALDI imaging MS. Zavalin A, Yang J, Haase A, Holle A, Caprioli R (2014) J Am Soc Mass Spectrom 25:1079-82 | 2014 |
| Reconstruction of SAXS Profiles from Protein Structures. Putnam DK, Lowe EW, Meiler J (2013) Comput Struct Biotechnol J 8:e201308006 | 2013 |
| Inverted topologies in membrane proteins: a mini-review. Duran AM, Meiler J (2013) Comput Struct Biotechnol J 8:e201308004 | 2013 |
| NF-κB gene signature predicts prostate cancer progression. Jin R, Yi Y, Yull FE, Blackwell TS, Clark PE, Koyama T, Smith JA, Matusik RJ (2014) Cancer Res 74:2763-72 | 2014 |
| MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery. Gessel MM, Norris JL, Caprioli RM (2014) J Proteomics 107:71-82 | 2014 |
| 5-methylcytosine recognition by Arabidopsis thaliana DNA glycosylases DEMETER and DML3. Brooks SC, Fischer RL, Huh JH, Eichman BF (2014) Biochemistry 53:2525-32 | 2014 |
| Deletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice. Zeng F, Miyazawa T, Kloepfer LA, Harris RC (2014) Kidney Int 86:538-47 | 2014 |
| Flipping the switch: integrin switching provides metastatic competence. Madamanchi A, Zijlstra A, Zutter MM (2014) Sci Signal 7:pe9 | 2014 |
| Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer. Feigin ME, Akshinthala SD, Araki K, Rosenberg AZ, Muthuswamy LB, Martin B, Lehmann BD, Berman HK, Pietenpol JA, Cardiff RD, Muthuswamy SK (2014) Cancer Res 74:3180-94 | 2014 |
| Excision of 5-hydroxymethylcytosine by DEMETER family DNA glycosylases. Jang H, Shin H, Eichman BF, Huh JH (2014) Biochem Biophys Res Commun 446:1067-72 | 2014 |
| Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens. Libes JM, Seeley EH, Li M, Axt JR, Pierce J, Correa H, Newton M, Hansen E, Judd A, McDonald H, Caprioli RM, Naranjo A, Huff V, O'Neill JA, Lovvorn HN, Kenyan Wilms Tumor Consortium (2014) J Am Coll Surg 218:707-20 | 2014 |
| The kidney research predicament. Bryan L, Ibrahim T, Zent R, Fischer MJ (2014) J Am Soc Nephrol 25:898-903 | 2014 |
| Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway. Tanwar V, Bylund JB, Hu J, Yan J, Walthall JM, Mukherjee A, Heaton WH, Wang WD, Potet F, Rai M, Kupershmidt S, Knapik EW, Hatzopoulos AK (2014) Stem Cells 32:1774-88 | 2014 |
| The lymphatic system in malignant pleural effusion. Drain or immune switch? Marazioti A, Blackwell TS, Stathopoulos GT (2014) Am J Respir Crit Care Med 189:626-7 | 2014 |
| The nuclear pore complex function of Sec13 protein is required for cell survival during retinal development. Niu X, Hong J, Zheng X, Melville DB, Knapik EW, Meng A, Peng J (2014) J Biol Chem 289:11971-85 | 2014 |
| Propagating the nephrology research workforce: a Kidney Research National Dialogue training commentary. Kohan DE, Parker MG, Furth SL, Hudson BG, Warburton KM, Rys-Sikora KE, Rankin TL, Kidney Research National Dialogue (2014) Clin J Am Soc Nephrol 9:1144-7 | 2014 |
| Interaction between bone morphogenetic protein receptor type 2 and estrogenic compounds in pulmonary arterial hypertension. Fessel JP, Chen X, Frump A, Gladson S, Blackwell T, Kang C, Johnson J, Loyd JE, Hemnes A, Austin E, West J (2013) Pulm Circ 3:564-77 | 2013 |
| Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC (2014) Science 344:58-64 | 2014 |
| The immune system in hypertension. Trott DW, Harrison DG (2014) Adv Physiol Educ 38:20-4 | 2014 |
| Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models. Doll CA, Broadie K (2014) Front Cell Neurosci 8:30 | 2014 |
| Neurovascular unit on a chip: implications for translational applications. Alcendor DJ, Block FE, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, Hofmeister LH, Li D, Markov DA, May JC, McCawley LJ, McLaughlin B, McLean JA, Niswender KD, Pensabene V, Seale KT, Sherrod SD, Sung HJ, Tabb DL, Webb DJ, Wikswo JP (2013) Stem Cell Res Ther 4 Suppl 1:S18 | 2013 |
| Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer. Udyavar AR, Hoeksema MD, Clark JE, Zou Y, Tang Z, Li Z, Li M, Chen H, Statnikov A, Shyr Y, Liebler DC, Field J, Eisenberg R, Estrada L, Massion PP, Quaranta V (2013) BMC Syst Biol 7 Suppl 5:S1 | 2013 |
| Role of vascular oxidative stress in obesity and metabolic syndrome. Youn JY, Siu KL, Lob HE, Itani H, Harrison DG, Cai H (2014) Diabetes 63:2344-55 | 2014 |
| New strategies for triple-negative breast cancer--deciphering the heterogeneity. Mayer IA, Abramson VG, Lehmann BD, Pietenpol JA (2014) Clin Cancer Res 20:782-90 | 2014 |
| Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction. Shi C, Washington MK, Chaturvedi R, Drosos Y, Revetta FL, Weaver CJ, Buzhardt E, Yull FE, Blackwell TS, Sosa-Pineda B, Whitehead RH, Beauchamp RD, Wilson KT, Means AL (2014) Lab Invest 94:409-21 | 2014 |
| Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance. Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S (2014) J Clin Invest 124:1098-113 | 2014 |
| Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site. Gregory KJ, Nguyen ED, Malosh C, Mendenhall JL, Zic JZ, Bates BS, Noetzel MJ, Squire EF, Turner EM, Rook JM, Emmitte KA, Stauffer SR, Lindsley CW, Meiler J, Conn PJ (2014) ACS Chem Neurosci 5:282-95 | 2014 |
| siRNA Delivery from an Injectable Scaffold for Wound Therapy. Nelson CE, Gupta MK, Adolph EJ, Guelcher SA, Duvall CL (2013) Adv Wound Care (New Rochelle) 2:93-99 | 2013 |
| Epidermal growth factor, from gene organization to bedside. Zeng F, Harris RC (2014) Semin Cell Dev Biol 28:2-11 | 2014 |
| The integrin β1 subunit regulates paracellular permeability of kidney proximal tubule cells. Elias BC, Mathew S, Srichai MB, Palamuttam R, Bulus N, Mernaugh G, Singh AB, Sanders CR, Harris RC, Pozzi A, Zent R (2014) J Biol Chem 289:8532-44 | 2014 |
| Embryonic domains of the aorta derived from diverse origins exhibit distinct properties that converge into a common phenotype in the adult. Pfaltzgraff ER, Shelton EL, Galindo CL, Nelms BL, Hooper CW, Poole SD, Labosky PA, Bader DM, Reese J (2014) J Mol Cell Cardiol 69:88-96 | 2014 |
| Motor and tail homology 1 (Th1) domains antagonistically control myosin-1 dynamics. Mazerik JN, Kraft LJ, Kenworthy AK, Tyska MJ (2014) Biophys J 106:649-58 | 2014 |
| A novel dyskerin (DKC1) mutation is associated with familial interstitial pneumonia. Kropski JA, Mitchell DB, Markin C, Polosukhin VV, Choi L, Johnson JE, Lawson WE, Phillips JA, Cogan JD, Blackwell TS, Loyd JE (2014) Chest 146:e1-e7 | 2014 |
| Imaging mass spectrometry: molecular microscopy for enabling a new age of discovery. Caprioli RM (2014) Proteomics 14:807-9 | 2014 |
| A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species. Martin JR, Gupta MK, Page JM, Yu F, Davidson JM, Guelcher SA, Duvall CL (2014) Biomaterials 35:3766-76 | 2014 |
| From ST segments to endothelial pathophysiology: hypercholesterolemia and endothelial superoxide production. Harrison DG (2014) J Clin Invest 124:473-5 | 2014 |
| Co-registration of multi-modality imaging allows for comprehensive analysis of tumor-induced bone disease. Seeley EH, Wilson KJ, Yankeelov TE, Johnson RW, Gore JC, Caprioli RM, Matrisian LM, Sterling JA (2014) Bone 61:208-16 | 2014 |
| In vivo cell biology in zebrafish - providing insights into vertebrate development and disease. Vacaru AM, Unlu G, Spitzner M, Mione M, Knapik EW, Sadler KC (2014) J Cell Sci 127:485-95 | 2014 |
| Analysis and isolation of adipocytes by flow cytometry. Majka SM, Miller HL, Helm KM, Acosta AS, Childs CR, Kong R, Klemm DJ (2014) Methods Enzymol 537:281-96 | 2014 |
| The immune profile associated with acute allergic asthma accelerates clearance of influenza virus. Samarasinghe AE, Woolard SN, Boyd KL, Hoselton SA, Schuh JM, McCullers JA (2014) Immunol Cell Biol 92:449-59 | 2014 |
| Biomaterial scaffolds for treating osteoporotic bone. Sterling JA, Guelcher SA (2014) Curr Osteoporos Rep 12:48-54 | 2014 |
| Adaptor protein2 (AP2) orchestrates CXCR2-mediated cell migration. Raman D, Sai J, Hawkins O, Richmond A (2014) Traffic 15:451-69 | 2014 |
| Smad6 suppresses the growth and self-renewal of hepatic progenitor cells. Ding ZY, Liang HF, Jin GN, Chen WX, Wang W, Datta PK, Zhang MZ, Zhang B, Chen XP (2014) J Cell Physiol 229:651-60 | 2014 |
| A microfluidic-enabled mechanical microcompressor for the immobilization of live single- and multi-cellular specimens. Yan Y, Jiang L, Aufderheide KJ, Wright GA, Terekhov A, Costa L, Qin K, McCleery WT, Fellenstein JJ, Ustione A, Robertson JB, Johnson CH, Piston DW, Hutson MS, Wikswo JP, Hofmeister W, Janetopoulos C (2014) Microsc Microanal 20:141-51 | 2014 |
| Lens capsule as a model to study type IV collagen. Cummings CF, Hudson BG (2014) Connect Tissue Res 55:8-12 | 2014 |
| Glomerular cell cross-talk influences composition and assembly of extracellular matrix. Byron A, Randles MJ, Humphries JD, Mironov A, Hamidi H, Harris S, Mathieson PW, Saleem MA, Satchell SC, Zent R, Humphries MJ, Lennon R (2014) J Am Soc Nephrol 25:953-66 | 2014 |
| Global analysis reveals the complexity of the human glomerular extracellular matrix. Lennon R, Byron A, Humphries JD, Randles MJ, Carisey A, Murphy S, Knight D, Brenchley PE, Zent R, Humphries MJ (2014) J Am Soc Nephrol 25:939-51 | 2014 |
| GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model. Gatto CL, Pereira D, Broadie K (2014) Neurobiol Dis 65:142-59 | 2014 |
| Cellular traction stresses mediate extracellular matrix degradation by invadopodia. Jerrell RJ, Parekh A (2014) Acta Biomater 10:1886-96 | 2014 |
| CXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathways. Sobolik T, Su YJ, Wells S, Ayers GD, Cook RS, Richmond A (2014) Mol Biol Cell 25:566-82 | 2014 |
| ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone. Hansen AG, Arnold SA, Jiang M, Palmer TD, Ketova T, Merkel A, Pickup M, Samaras S, Shyr Y, Moses HL, Hayward SW, Sterling JA, Zijlstra A (2014) Cancer Res 74:1404-15 | 2014 |
| Computational methods in drug discovery. Sliwoski G, Kothiwale S, Meiler J, Lowe EW (2014) Pharmacol Rev 66:334-95 | 2014 |
| Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket. Pedragosa-Badia X, Sliwoski GR, Dong Nguyen E, Lindner D, Stichel J, Kaufmann KW, Meiler J, Beck-Sickinger AG (2014) J Biol Chem 289:5846-59 | 2014 |
| The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt. Capdevila JH, Pidkovka N, Mei S, Gong Y, Falck JR, Imig JD, Harris RC, Wang W (2014) J Biol Chem 289:4377-86 | 2014 |
| Neonatal Fc receptor promotes immune complex-mediated glomerular disease. Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB (2014) J Am Soc Nephrol 25:918-25 | 2014 |
| The chick embryo as an expanding experimental model for cancer and cardiovascular research. Kain KH, Miller JW, Jones-Paris CR, Thomason RT, Lewis JD, Bader DM, Barnett JV, Zijlstra A (2014) Dev Dyn 243:216-28 | 2014 |
| Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Balko JM, Giltnane JM, Wang K, Schwarz LJ, Young CD, Cook RS, Owens P, Sanders ME, Kuba MG, Sánchez V, Kurupi R, Moore PD, Pinto JA, Doimi FD, Gómez H, Horiuchi D, Goga A, Lehmann BD, Bauer JA, Pietenpol JA, Ross JS, Palmer GA, Yelensky R, Cronin M, Miller VA, Stephens PJ, Arteaga CL (2014) Cancer Discov 4:232-45 | 2014 |
| NF-κB inhibition after cecal ligation and puncture reduces sepsis-associated lung injury without altering bacterial host defense. Li H, Han W, Polosukhin V, Yull FE, Segal BH, Xie CM, Blackwell TS (2013) Mediators Inflamm 2013:503213 | 2013 |
| Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase. Wu J, Thabet SR, Kirabo A, Trott DW, Saleh MA, Xiao L, Madhur MS, Chen W, Harrison DG (2014) Circ Res 114:616-25 | 2014 |
| BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition. Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W (2013) Clin Cancer Res 19:6696-702 | 2013 |
| A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT, Aspirnauts, Hudson JK, Hudson BG (2014) Proc Natl Acad Sci U S A 111:331-6 | 2014 |
| Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression. Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK (2013) PLoS One 8:e82684 | 2013 |
| Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo. Nelson CE, Kim AJ, Adolph EJ, Gupta MK, Yu F, Hocking KM, Davidson JM, Guelcher SA, Duvall CL (2014) Adv Mater 26:607-14, 506 | 2014 |
| Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases. Unlu G, Levic DS, Melville DB, Knapik EW (2014) Int J Biochem Cell Biol 47:57-67 | 2014 |
| Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients. McLaughlin B, Gidday JM (2013) Transl Stroke Res 4:104-13 | 2013 |
| Modulation of behavioral networks by selective interneuronal inactivation. Schmidt MJ, Horvath S, Ebert P, Norris JL, Seeley EH, Brown J, Gellert L, Everheart M, Garbett KA, Grice TW, Caprioli RM, Mirnics K (2014) Mol Psychiatry 19:580-7 | 2014 |
| Simultaneous prediction of binding free energy and specificity for PDZ domain-peptide interactions. Crivelli JJ, Lemmon G, Kaufmann KW, Meiler J (2013) J Comput Aided Mol Des 27:1051-65 | 2013 |
| Comparative study of exome copy number variation estimation tools using array comparative genomic hybridization as control. Guo Y, Sheng Q, Samuels DC, Lehmann B, Bauer JA, Pietenpol J, Shyr Y (2013) Biomed Res Int 2013:915636 | 2013 |
| PPARα activation can help prevent and treat non-small cell lung cancer. Skrypnyk N, Chen X, Hu W, Su Y, Mont S, Yang S, Gangadhariah M, Wei S, Falck JR, Jat JL, Zent R, Capdevila JH, Pozzi A (2014) Cancer Res 74:621-31 | 2014 |
| Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release. Alexander NS, Preininger AM, Kaya AI, Stein RA, Hamm HE, Meiler J (2014) Nat Struct Mol Biol 21:56-63 | 2014 |
| Exosome secretion is enhanced by invadopodia and drives invasive behavior. Hoshino D, Kirkbride KC, Costello K, Clark ES, Sinha S, Grega-Larson N, Tyska MJ, Weaver AM (2013) Cell Rep 5:1159-68 | 2013 |
| The substrate binding interface of alkylpurine DNA glycosylase AlkD. Mullins EA, Rubinson EH, Eichman BF (2014) DNA Repair (Amst) 13:50-4 | 2014 |
| Mouse models and anti-HER2 therapies. Hanker AB, Cook RS, Arteaga CL (2013) Oncotarget 4:1866-7 | 2013 |
| Cellularized cylindrical fiber/hydrogel composites for ligament tissue engineering. Thayer PS, Dimling AF, Plessl DS, Hahn MR, Guelcher SA, Dahlgren LA, Goldstein AS (2014) Biomacromolecules 15:75-83 | 2014 |
| Bronchoscopic cryobiopsy for the diagnosis of diffuse parenchymal lung disease. Kropski JA, Pritchett JM, Mason WR, Sivarajan L, Gleaves LA, Johnson JE, Lancaster LH, Lawson WE, Blackwell TS, Steele MP, Loyd JE, Rickman OB (2013) PLoS One 8:e78674 | 2013 |
| The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development. Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML (2014) Cancer Res 74:38-43 | 2014 |
| Insights into eukaryotic primer synthesis from structures of the p48 subunit of human DNA primase. Vaithiyalingam S, Arnett DR, Aggarwal A, Eichman BF, Fanning E, Chazin WJ (2014) J Mol Biol 426:558-69 | 2014 |
| N-glycosylation requirements in neuromuscular synaptogenesis. Parkinson W, Dear ML, Rushton E, Broadie K (2013) Development 140:4970-81 | 2013 |
| Cryogenic Etching of Silicon: An Alternative Method For Fabrication of Vertical Microcantilever Master Molds. Addae-Mensah KA, Retterer S, Opalenik SR, Thomas D, Lavrik NV, Wikswo JP (2009) J Microelectromech Syst 19: | 2009 |
| Integrin-free tetraspanin CD151 can inhibit tumor cell motility upon clustering and is a clinical indicator of prostate cancer progression. Palmer TD, Martínez CH, Vasquez C, Hebron KE, Jones-Paris C, Arnold SA, Chan SM, Chalasani V, Gomez-Lemus JA, Williams AK, Chin JL, Giannico GA, Ketova T, Lewis JD, Zijlstra A (2014) Cancer Res 74:173-87 | 2014 |
| Identification of promethazine as an amyloid-binding molecule using a fluorescence high-throughput assay and MALDI imaging mass spectrometry. McClure RA, Chumbley CW, Reyzer ML, Wilson K, Caprioli RM, Gore JC, Pham W (2013) Neuroimage Clin 2:620-9 | 2013 |
| Imaging mass spectrometry: a new tool for pathology in a molecular age. Norris JL, Caprioli RM (2013) Proteomics Clin Appl 7:733-8 | 2013 |
| Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP (2014) Am J Respir Crit Care Med 189:214-22 | 2014 |
| Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney. Zhang MZ, Wang Y, Yao B, Gewin L, Wei S, Capdevila JH, Harris RC (2013) Am J Physiol Renal Physiol 305:F1680-6 | 2013 |
| The roles of TGFβ in the tumour microenvironment. Pickup M, Novitskiy S, Moses HL (2013) Nat Rev Cancer 13:788-99 | 2013 |
| Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer. Walsh AJ, Cook RS, Manning HC, Hicks DJ, Lafontant A, Arteaga CL, Skala MC (2013) Cancer Res 73:6164-74 | 2013 |
| Preparation of (-)-Nutlin-3 using enantioselective organocatalysis at decagram scale. Davis TA, Vilgelm AE, Richmond A, Johnston JN (2013) J Org Chem 78:10605-16 | 2013 |
| Injectable foams for regenerative medicine. Prieto EM, Page JM, Harmata AJ, Guelcher SA (2014) Wiley Interdiscip Rev Nanomed Nanobiotechnol 6:136-54 | 2014 |
| Optimizing personalized bone marrow testing using an evidence-based, interdisciplinary team approach. Seegmiller AC, Kim AS, Mosse CA, Levy MA, Thompson MA, Kressin MK, Jagasia MH, Strickland SA, Reddy NM, Marx ER, Sinkfield KJ, Pollard HN, Plummer WD, Dupont WD, Shultz EK, Dittus RS, Stead WW, Santoro SA, Zutter MM (2013) Am J Clin Pathol 140:643-50 | 2013 |
| BCL::Fold--protein topology determination from limited NMR restraints. Weiner BE, Alexander N, Akin LR, Woetzel N, Karakas M, Meiler J (2014) Proteins 82:587-95 | 2014 |
| SRChing for the substrates of Src. Reynolds AB, Kanner SB, Bouton AH, Schaller MD, Weed SA, Flynn DC, Parsons JT (2014) Oncogene 33:4537-47 | 2014 |
| Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes. Lehmann BD, Pietenpol JA (2014) J Pathol 232:142-50 | 2014 |
| EphA2 signaling following endocytosis: role of Tiam1. Boissier P, Chen J, Huynh-Do U (2013) Traffic 14:1255-71 | 2013 |
| Transmembrane current imaging in the heart during pacing and fibrillation. Gray RA, Mashburn DN, Sidorov VY, Roth BJ, Pathmanathan P, Wikswo JP (2013) Biophys J 105:1710-9 | 2013 |
| Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone. Rubinson EH, Christov PP, Eichman BF (2013) Biochemistry 52:7363-5 | 2013 |
| Systemic delivery of microRNA-181b inhibits nuclear factor-κB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice. Sun X, He S, Wara AKM, Icli B, Shvartz E, Tesmenitsky Y, Belkin N, Li D, Blackwell TS, Sukhova GK, Croce K, Feinberg MW (2014) Circ Res 114:32-40 | 2014 |
| Hypoxia-induced expression of VEGF splice variants and protein in four retinal cell types. Watkins WM, McCollum GW, Savage SR, Capozzi ME, Penn JS, Morrison DG (2013) Exp Eye Res 116:240-6 | 2013 |
| What lies beneath: looking beyond tumor genetics shows the complexity of signaling networks underlying drug sensitivity. Quaranta V, Tyson DR (2013) Sci Signal 6:pe32 | 2013 |
| Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. Dikalov SI, Nazarewicz RR, Bikineyeva A, Hilenski L, Lassègue B, Griendling KK, Harrison DG, Dikalova AE (2014) Antioxid Redox Signal 20:281-94 | 2014 |
| The role of the NFAT signaling pathway in retinal neovascularization. Bretz CA, Savage S, Capozzi M, Penn JS (2013) Invest Ophthalmol Vis Sci 54:7020-7 | 2013 |
| Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254). Turlington M, Noetzel MJ, Chun A, Zhou Y, Gogliotti RD, Nguyen ED, Gregory KJ, Vinson PN, Rook JM, Gogi KK, Xiang Z, Bridges TM, Daniels JS, Jones C, Niswender CM, Meiler J, Conn PJ, Lindsley CW, Stauffer SR (2013) J Med Chem 56:7976-96 | 2013 |
| Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition. Benesh EC, Miller PM, Pfaltzgraff ER, Grega-Larson NE, Hager HA, Sung BH, Qu X, Baldwin HS, Weaver AM, Bader DM (2013) Mol Biol Cell 24:3496-510 | 2013 |
| Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila. Friedman SH, Dani N, Rushton E, Broadie K (2013) Dis Model Mech 6:1400-13 | 2013 |
| Loss of mitochondrial protein Fus1 augments host resistance to Acinetobacter baumannii infection. Hood MI, Uzhachenko R, Boyd K, Skaar EP, Ivanova AV (2013) Infect Immun 81:4461-9 | 2013 |
| RosettaEPR: rotamer library for spin label structure and dynamics. Alexander NS, Stein RA, Koteiche HA, Kaufmann KW, McHaourab HS, Meiler J (2013) PLoS One 8:e72851 | 2013 |
| Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2. Kim KH, Sadikot RT, Xiao L, Christman JW, Freeman ML, Chan JY, Oh YK, Blackwell TS, Joo M (2013) Free Radic Biol Med 65:1134-42 | 2013 |
| Retinal angiogenesis suppression through small molecule activation of p53. Chavala SH, Kim Y, Tudisco L, Cicatiello V, Milde T, Kerur N, Claros N, Yanni S, Guaiquil VH, Hauswirth WW, Penn JS, Rafii S, De Falco S, Lee TC, Ambati J (2013) J Clin Invest 123:4170-81 | 2013 |
| Isolevuglandin-modified phosphatidylethanolamine is metabolized by NAPE-hydrolyzing phospholipase D. Guo L, Gragg SD, Chen Z, Zhang Y, Amarnath V, Davies SS (2013) J Lipid Res 54:3151-7 | 2013 |
| An LC-MS assay for the screening of cardiovascular medications in human samples. Dias E, Hachey B, McNaughton C, Nian H, Yu C, Straka B, Brown NJ, Caprioli RM (2013) J Chromatogr B Analyt Technol Biomed Life Sci 937:44-53 | 2013 |
| Repeatability and sensitivity of high resolution blood volume mapping in mouse kidney disease. Wang F, Jiang RT, Tantawy MN, Borza DB, Takahashi K, Gore JC, Harris RC, Takahashi T, Quarles CC (2014) J Magn Reson Imaging 39:866-71 | 2014 |
| ErbB3 downregulation enhances luminal breast tumor response to antiestrogens. Morrison MM, Hutchinson K, Williams MM, Stanford JC, Balko JM, Young C, Kuba MG, Sánchez V, Williams AJ, Hicks DJ, Arteaga CL, Prat A, Perou CM, Earp HS, Massarweh S, Cook RS (2013) J Clin Invest 123:4329-43 | 2013 |
| Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE (2013) J Clin Invest 123:4405-9 | 2013 |
| Octarellin VI: using rosetta to design a putative artificial (β/α)8 protein. Figueroa M, Oliveira N, Lejeune A, Kaufmann KW, Dorr BM, Matagne A, Martial JA, Meiler J, Van de Weerdt C (2013) PLoS One 8:e71858 | 2013 |
| Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer. Balko JM, Schwarz LJ, Bhola NE, Kurupi R, Owens P, Miller TW, Gómez H, Cook RS, Arteaga CL (2013) Cancer Res 73:6346-58 | 2013 |
| Ischemia-reperfusion model of acute kidney injury and post injury fibrosis in mice. Skrypnyk NI, Harris RC, de Caestecker MP (2013) J Vis Exp : | 2013 |
| Computational design of protein-small molecule interfaces. Allison B, Combs S, DeLuca S, Lemmon G, Mizoue L, Meiler J (2014) J Struct Biol 185:193-202 | 2014 |
| Iterative Molecular Dynamics-Rosetta Protein Structure Refinement Protocol to Improve Model Quality. Lindert S, Meiler J, McCammon JA (2013) J Chem Theory Comput 9:3843-3847 | 2013 |
| Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides. Li F, Xia Y, Meiler J, Ferguson-Miller S (2013) Biochemistry 52:5884-99 | 2013 |
| Survivin mediates renal proximal tubule recovery from AKI. Chen J, Chen JK, Conway EM, Harris RC (2013) J Am Soc Nephrol 24:2023-33 | 2013 |
| Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes. Masuda H, Baggerly KA, Wang Y, Zhang Y, Gonzalez-Angulo AM, Meric-Bernstam F, Valero V, Lehmann BD, Pietenpol JA, Hortobagyi GN, Symmans WF, Ueno NT (2013) Clin Cancer Res 19:5533-40 | 2013 |
| Balancing the rates of new bone formation and polymer degradation enhances healing of weight-bearing allograft/polyurethane composites in rabbit femoral defects. Dumas JE, Prieto EM, Zienkiewicz KJ, Guda T, Wenke JC, Bible J, Holt GE, Guelcher SA (2014) Tissue Eng Part A 20:115-29 | 2014 |
| Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies. Hanker AB, Pfefferle AD, Balko JM, Kuba MG, Young CD, Sánchez V, Sutton CR, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL (2013) Proc Natl Acad Sci U S A 110:14372-7 | 2013 |
| 11β-Hydroxysteroid Dehydrogenase Type II is a Potential Target for Prevention of Colorectal Tumorigenesis. Yang S, Jiang L, Zhang MZ (2013) J Oncobiomarkers 1: | 2013 |
| Autotaxin signaling governs phenotypic heterogeneity in visceral and parietal mesothelia. Shelton EL, Galindo CL, Williams CH, Pfaltzgraff E, Hong CC, Bader DM (2013) PLoS One 8:e69712 | 2013 |
| Targeting the Wnt pathway in synovial sarcoma models. Barham W, Frump AL, Sherrill TP, Garcia CB, Saito-Diaz K, VanSaun MN, Fingleton B, Gleaves L, Orton D, Capecchi MR, Blackwell TS, Lee E, Yull F, Eid JE (2013) Cancer Discov 3:1286-301 | 2013 |
| Delayed marrow infusion in mice enhances hematopoietic and osteopoietic engraftment by facilitating transient expansion of the osteoblastic niche. Marino R, Otsuru S, Hofmann TJ, Olson TS, Rasini V, Veronesi E, Boyd K, Gaber MW, Martinez C, Paolucci P, Dominici M, Horwitz EM (2013) Biol Blood Marrow Transplant 19:1566-73 | 2013 |
| Increased dietary sodium induces COX2 expression by activating NFκB in renal medullary interstitial cells. He W, Zhang M, Zhao M, Davis LS, Blackwell TS, Yull F, Breyer MD, Hao CM (2014) Pflugers Arch 466:357-367 | 2014 |
| Mcm10 self-association is mediated by an N-terminal coiled-coil domain. Du W, Josephrajan A, Adhikary S, Bowles T, Bielinsky AK, Eichman BF (2013) PLoS One 8:e70518 | 2013 |
| Mouse models of membranous nephropathy: the road less travelled by. Borza DB, Zhang JJ, Beck LH, Meyer-Schwesinger C, Luo W (2013) Am J Clin Exp Immunol 2:135-45 | 2013 |
| CaMKII is essential for the proasthmatic effects of oxidation. Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, Dworski R, Sammut D, Wagner BA, Buettner GR, Pope RM, Miller FJ, Dibbern ME, Haitchi HM, Mohler PJ, Howarth PH, Zabner J, Kline JN, Grumbach IM, Anderson ME (2013) Sci Transl Med 5:195ra97 | 2013 |
| An HPLC-tandem mass spectrometry method for simultaneous detection of alkylated base excision repair products. Mullins EA, Rubinson EH, Pereira KN, Calcutt MW, Christov PP, Eichman BF (2013) Methods 64:59-66 | 2013 |
| Physiologic and pathophysiologic roles of cyclooxygenase-2 in the kidney. Harris RC (2013) Trans Am Clin Climatol Assoc 124:139-51 | 2013 |
| Diastolic field stimulation: the role of shock duration in epicardial activation and propagation. Woods MC, Uzelac I, Holcomb MR, Wikswo JP, Sidorov VY (2013) Biophys J 105:523-32 | 2013 |
| Synthetic and tissue-derived models for studying rigidity effects on invadopodia activity. Weaver AM, Page JM, Guelcher SA, Parekh A (2013) Methods Mol Biol 1046:171-89 | 2013 |
| MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. Cook RS, Jacobsen KM, Wofford AM, DeRyckere D, Stanford J, Prieto AL, Redente E, Sandahl M, Hunter DM, Strunk KE, Graham DK, Earp HS (2013) J Clin Invest 123:3231-42 | 2013 |
| Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis. Barrett CW, Singh K, Motley AK, Lintel MK, Matafonova E, Bradley AM, Ning W, Poindexter SV, Parang B, Reddy VK, Chaturvedi R, Fingleton BM, Washington MK, Wilson KT, Davies SS, Hill KE, Burk RF, Williams CS (2013) PLoS One 8:e67845 | 2013 |
| Mechanistic analysis of challenge-response experiments. Shotwell MS, Drake KJ, Sidorov VY, Wikswo JP (2013) Biometrics 69:741-7 | 2013 |
| Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas. Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL (2013) Cancer Res 73:5336-46 | 2013 |
| Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface. Attia AS, Cassat JE, Aranmolate SO, Zimmerman LJ, Boyd KL, Skaar EP (2013) Pathog Dis 69:36-48 | 2013 |
| Enrichment of elevated plasma F2t-isoprostane levels in individuals with autism who are stratified by presence of gastrointestinal dysfunction. Gorrindo P, Lane CJ, Lee EB, McLaughlin B, Levitt P (2013) PLoS One 8:e68444 | 2013 |
| Assessment and challenges of ligand docking into comparative models of G-protein coupled receptors. Nguyen ED, Norn C, Frimurer TM, Meiler J (2013) PLoS One 8:e67302 | 2013 |
| Towards ligand docking including explicit interface water molecules. Lemmon G, Meiler J (2013) PLoS One 8:e67536 | 2013 |
| Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion. Owens P, Polikowsky H, Pickup MW, Gorska AE, Jovanovic B, Shaw AK, Novitskiy SV, Hong CC, Moses HL (2013) PLoS One 8:e67533 | 2013 |
| Effects of local delivery of D-amino acids from biofilm-dispersive scaffolds on infection in contaminated rat segmental defects. Sanchez CJ, Prieto EM, Krueger CA, Zienkiewicz KJ, Romano DR, Ward CL, Akers KS, Guelcher SA, Wenke JC (2013) Biomaterials 34:7533-43 | 2013 |
| MALDI imaging and in situ identification of integral membrane proteins from rat brain tissue sections. Nicklay JJ, Harris GA, Schey KL, Caprioli RM (2013) Anal Chem 85:7191-6 | 2013 |
| Scaling and systems biology for integrating multiple organs-on-a-chip. Wikswo JP, Curtis EL, Eagleton ZE, Evans BC, Kole A, Hofmeister LH, Matloff WJ (2013) Lab Chip 13:3496-511 | 2013 |
| MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Kehl-Fie TE, Zhang Y, Moore JL, Farrand AJ, Hood MI, Rathi S, Chazin WJ, Caprioli RM, Skaar EP (2013) Infect Immun 81:3395-405 | 2013 |
| Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas. Ivanov SV, Panaccione A, Nonaka D, Prasad ML, Boyd KL, Brown B, Guo Y, Sewell A, Yarbrough WG (2013) Br J Cancer 109:444-51 | 2013 |
| Diabetic nephropathy: a national dialogue. Breyer MD, Coffman TM, Flessner MF, Fried LF, Harris RC, Ketchum CJ, Kretzler M, Nelson RG, Sedor JR, Susztak K, Kidney Research National Dialogue (KRND) (2013) Clin J Am Soc Nephrol 8:1603-5 | 2013 |
| A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1. Yazlovitskaya EM, Uzhachenko R, Voziyan PA, Yarbrough WG, Ivanova AV (2013) Cell Death Dis 4:e687 | 2013 |
| Redox modification of proteins as essential mediators of CNS autophagy and mitophagy. Lizama-Manibusan B, McLaughlin B (2013) FEBS Lett 587:2291-8 | 2013 |
| Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression. Miyazawa T, Zeng F, Wang S, Fan X, Cheng H, Yang H, Bian A, Fogo AB, Harris RC (2013) Kidney Int 84:1176-88 | 2013 |
| Imaging mass spectrometry for assessing temporal proteomics: analysis of calprotectin in Acinetobacter baumannii pulmonary infection. Moore JL, Becker KW, Nicklay JJ, Boyd KL, Skaar EP, Caprioli RM (2014) Proteomics 14:820-828 | 2014 |
| Imaging of endothelial progenitor cell subpopulations in angiogenesis using quantum dot nanocrystals. Barnett JM, Penn JS, Jayagopal A (2013) Methods Mol Biol 1026:45-56 | 2013 |
| A common functional promoter variant links CNR1 gene expression to HDL cholesterol level. Feng Q, Vickers KC, Anderson MP, Levin MG, Chen W, Harrison DG, Wilke RA (2013) Nat Commun 4:1973 | 2013 |
| Substrate-selective repair and restart of replication forks by DNA translocases. Bétous R, Couch FB, Mason AC, Eichman BF, Manosas M, Cortez D (2013) Cell Rep 3:1958-69 | 2013 |
| SDF-1 fused to a fractalkine stalk and a GPI anchor enables functional neovascularization. Stachel G, Trenkwalder T, Götz F, El Aouni C, Muenchmeier N, Pfosser A, Nussbaum C, Sperandio M, Hatzopoulos AK, Hinkel R, Nelson PJ, Kupatt C (2013) Stem Cells 31:1795-805 | 2013 |
| Small-molecule ligand docking into comparative models with Rosetta. Combs SA, Deluca SL, Deluca SH, Lemmon GH, Nannemann DP, Nguyen ED, Willis JR, Sheehan JH, Meiler J (2013) Nat Protoc 8:1277-98 | 2013 |
| Epithelial-specific deletion of 11β-HSD2 hinders Apcmin/+ mouse tumorigenesis. Jiang L, Yang S, Yin H, Fan X, Wang S, Yao B, Pozzi A, Chen X, Harris RC, Zhang MZ (2013) Mol Cancer Res 11:1040-50 | 2013 |
| An exclusively mesodermal origin of fin mesenchyme demonstrates that zebrafish trunk neural crest does not generate ectomesenchyme. Lee RT, Knapik EW, Thiery JP, Carney TJ (2013) Development 140:2923-32 | 2013 |
| Cyclooxygenase metabolites in the kidney. Harris RC, Zhang MZ (2011) Compr Physiol 1:1729-58 | 2011 |
| BCL::MP-fold: folding membrane proteins through assembly of transmembrane helices. Weiner BE, Woetzel N, Karakaş M, Alexander N, Meiler J (2013) Structure 21:1107-17 | 2013 |
| Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling. Ding ZY, Jin GN, Liang HF, Wang W, Chen WX, Datta PK, Zhang MZ, Zhang B, Chen XP (2013) Cell Signal 25:1981-92 | 2013 |
| Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation. Scott SA, Xiang Y, Mathews TP, Cho HP, Myers DS, Armstrong MD, Tallman KA, O'Reilly MC, Lindsley CW, Brown HA (2013) J Biol Chem 288:20477-87 | 2013 |
| Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. Wiig H, Schröder A, Neuhofer W, Jantsch J, Kopp C, Karlsen TV, Boschmann M, Goss J, Bry M, Rakova N, Dahlmann A, Brenner S, Tenstad O, Nurmi H, Mervaala E, Wagner H, Beck FX, Müller DN, Kerjaschki D, Luft FC, Harrison DG, Alitalo K, Titze J (2013) J Clin Invest 123:2803-15 | 2013 |
| Clinically relevant modeling of tumor growth and treatment response. Yankeelov TE, Atuegwu N, Hormuth D, Weis JA, Barnes SL, Miga MI, Rericha EC, Quaranta V (2013) Sci Transl Med 5:187ps9 | 2013 |
| Peroxisome proliferator-activated receptor-β/δ regulates angiogenic cell behaviors and oxygen-induced retinopathy. Capozzi ME, McCollum GW, Savage SR, Penn JS (2013) Invest Ophthalmol Vis Sci 54:4197-207 | 2013 |
| Senescent T cells and hypertension: new ideas about old cells. Madhur MS, Harrison DG (2013) Hypertension 62:13-5 | 2013 |
| Is expression of p120ctn in oral squamous cell carcinomas a prognostic factor? Lo Muzio L, Pannone G, Santarelli A, Bambini F, Mascitti M, Rubini C, Testa NF, Dioguardi M, Leuci S, Bascones A, Reynolds AB, Mariggiò MA (2013) Oral Surg Oral Med Oral Pathol Oral Radiol 115:789-98 | 2013 |
| Adipose lineage specification of bone marrow-derived myeloid cells. Majka SM, Miller HL, Sullivan T, Erickson PF, Kong R, Weiser-Evans M, Nemenoff R, Moldovan R, Morandi SA, Davis JA, Klemm DJ (2012) Adipocyte 1:215-229 | 2012 |
| WAVE2 regulates epithelial morphology and cadherin isoform switching through regulation of Twist and Abl. Bryce NS, Reynolds AB, Koleske AJ, Weaver AM (2013) PLoS One 8:e64533 | 2013 |
| Cdc42 promotes host defenses against fatal infection. Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R (2013) Infect Immun 81:2714-23 | 2013 |
| Dynamic dosing assay relating real-time respiration responses of Staphylococcus aureus biofilms to changing microchemical conditions. Deng J, Dhummakupt A, Samson PC, Wikswo JP, Shor LM (2013) Anal Chem 85:5411-9 | 2013 |
| Primary epiphyseal arteriopathy in a mouse model of steroid-induced osteonecrosis. Janke LJ, Liu C, Vogel P, Kawedia J, Boyd KL, Funk AJ, Relling MV (2013) Am J Pathol 183:19-25 | 2013 |
| Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL, Nannemann DP, Meiler J, Stewart PL, Crowe JE (2013) PLoS One 8:e61101 | 2013 |
| Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling. Chow K, Fessel JP, Kaoriihida-Stansbury , Schmidt EP, Gaskill C, Alvarez D, Graham B, Harrison DG, Wagner DH, Nozik-Grayck E, West JD, Klemm DJ, Majka SM (2013) Pulm Circ 3:31-49 | 2013 |
| Design and development of reactive injectable and settable polymeric biomaterials. Page JM, Harmata AJ, Guelcher SA (2013) J Biomed Mater Res A 101:3630-45 | 2013 |
| Laser beam filtration for high spatial resolution MALDI imaging mass spectrometry. Zavalin A, Yang J, Caprioli R (2013) J Am Soc Mass Spectrom 24:1153-6 | 2013 |
| Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice. Moik D, Böttcher A, Makhina T, Grashoff C, Bulus N, Zent R, Fässler R (2013) J Biol Chem 288:18863-71 | 2013 |
| Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability. Zebda N, Tian Y, Tian X, Gawlak G, Higginbotham K, Reynolds AB, Birukova AA, Birukov KG (2013) J Biol Chem 288:18290-9 | 2013 |
| Integrins in kidney disease. Pozzi A, Zent R (2013) J Am Soc Nephrol 24:1034-9 | 2013 |
| Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe. Engers DW, Frist AY, Lindsley CW, Hong CC, Hopkins CR (2013) Bioorg Med Chem Lett 23:3248-52 | 2013 |
| Human germline antibody gene segments encode polyspecific antibodies. Willis JR, Briney BS, DeLuca SL, Crowe JE, Meiler J (2013) PLoS Comput Biol 9:e1003045 | 2013 |
| T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells. Sandy AR, Chung J, Toubai T, Shan GT, Tran IT, Friedman A, Blackwell TS, Reddy P, King PD, Maillard I (2013) J Immunol 190:5818-28 | 2013 |
| Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling. Young CD, Pfefferle AD, Owens P, Kuba MG, Rexer BN, Balko JM, Sánchez V, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL (2013) Cancer Res 73:4075-85 | 2013 |
| Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureus. Mike LA, Dutter BF, Stauff DL, Moore JL, Vitko NP, Aranmolate O, Kehl-Fie TE, Sullivan S, Reid PR, DuBois JL, Richardson AR, Caprioli RM, Sulikowski GA, Skaar EP (2013) Proc Natl Acad Sci U S A 110:8206-11 | 2013 |
| Extracellular vesicles: communication, coercion, and conditioning. Shifrin DA, Demory Beckler M, Coffey RJ, Tyska MJ (2013) Mol Biol Cell 24:1253-9 | 2013 |
| The potential for resident lung mesenchymal stem cells to promote functional tissue regeneration: understanding microenvironmental cues. Foronjy RF, Majka SM (2012) Cells 1:874 | 2012 |
| Quaternary epitopes of α345(IV) collagen initiate Alport post-transplant anti-GBM nephritis. Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB (2013) J Am Soc Nephrol 24:889-95 | 2013 |
| Spiroaminal Model Systems of the Marineosins with Final Step Pyrrole Incorporation. Panarese JD, Konkol LC, Berry CB, Bates BS, Aldrich LN, Lindsley CW (2013) Tetrahedron Lett 54:2231-2234 | 2013 |
| Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective. Preininger AM, Meiler J, Hamm HE (2013) J Mol Biol 425:2288-98 | 2013 |
| Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34. Parekh VV, Wu L, Boyd KL, Williams JA, Gaddy JA, Olivares-Villagómez D, Cover TL, Zong WX, Zhang J, Van Kaer L (2013) J Immunol 190:5086-101 | 2013 |
| Cyclooxygenase-2-derived prostaglandin E₂ promotes injury-induced vascular neointimal hyperplasia through the E-prostanoid 3 receptor. Zhang J, Zou F, Tang J, Zhang Q, Gong Y, Wang Q, Shen Y, Xiong L, Breyer RM, Lazarus M, Funk CD, Yu Y (2013) Circ Res 113:104-14 | 2013 |
| Deficiency of gp91phox inhibits allergic airway inflammation. Sevin CM, Newcomb DC, Toki S, Han W, Sherrill TP, Boswell MG, Zhu Z, Collins RD, Boyd KL, Goleniewska K, Huckabee MM, Blackwell TS, Peebles RS (2013) Am J Respir Cell Mol Biol 49:396-402 | 2013 |
| Transplanted murine long-term repopulating hematopoietic cells can differentiate to osteoblasts in the marrow stem cell niche. Hofmann TJ, Otsuru S, Marino R, Rasini V, Veronesi E, Murgia A, Lahti J, Boyd K, Dominici M, Horwitz EM (2013) Mol Ther 21:1224-31 | 2013 |
| Passage-dependent cancerous transformation of human mesenchymal stem cells under carcinogenic hypoxia. Crowder SW, Horton LW, Lee SH, McClain CM, Hawkins OE, Palmer AM, Bae H, Richmond A, Sung HJ (2013) FASEB J 27:2788-98 | 2013 |
| Knock, knock: who's there?: Nox1. Itani HA, Dikalov S, Harrison DG (2013) Circulation 127:1850-2 | 2013 |
| Ephrin-Eph signaling as a potential therapeutic target for the treatment of myocardial infarction. O'Neal WT, Griffin WF, Dries-Devlin JL, Kent SD, Chen J, Willis MS, Virag JA (2013) Med Hypotheses 80:738-44 | 2013 |
| Discovery of ML326: The first sub-micromolar, selective M5 PAM. Gentry PR, Bridges TM, Lamsal A, Vinson PN, Smith E, Chase P, Hodder PS, Engers JL, Niswender CM, Daniels JS, Conn PJ, Wood MR, Lindsley CW (2013) Bioorg Med Chem Lett 23:2996-3000 | 2013 |
| Substrain-specific differences in survival and osteonecrosis incidence in a mouse model. Kawedia JD, Janke L, Funk AJ, Ramsey LB, Liu C, Jenkins D, Boyd KL, Relling MV (2012) Comp Med 62:466-71 | 2012 |
| Interactions between NF-κB and SP3 connect inflammatory signaling with reduced FGF-10 expression. Carver BJ, Plosa EJ, Stinnett AM, Blackwell TS, Prince LS (2013) J Biol Chem 288:15318-25 | 2013 |
| Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. Yu KD, Zhu R, Zhan M, Rodriguez AA, Yang W, Wong S, Makris A, Lehmann BD, Chen X, Mayer I, Pietenpol JA, Shao ZM, Symmans WF, Chang JC (2013) Clin Cancer Res 19:2723-33 | 2013 |
| Self-limiting outbreak of crayfish plague in an Austropotamobius pallipes population of a river basin in the Abruzzi region (central Italy). Caprioli R, Cargini D, Marcacci M, Cammà C, Giansante C, Ferri N (2013) Dis Aquat Organ 103:149-56 | 2013 |
| Discovering naturally processed antigenic determinants that confer protective T cell immunity. Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE, Williams JV, Buus S, Sette A, Schumacher TN, Link AJ, Joyce S (2013) J Clin Invest 123:1976-87 | 2013 |
| Elevated ALCAM shedding in colorectal cancer correlates with poor patient outcome. Hansen AG, Freeman TJ, Arnold SA, Starchenko A, Jones-Paris CR, Gilger MA, Washington MK, Fan KH, Shyr Y, Beauchamp RD, Zijlstra A (2013) Cancer Res 73:2955-64 | 2013 |
| Adverse drug events during AKI and its recovery. Cox ZL, McCoy AB, Matheny ME, Bhave G, Peterson NB, Siew ED, Lewis J, Danciu I, Bian A, Shintani A, Ikizler TA, Neal EB, Peterson JF (2013) Clin J Am Soc Nephrol 8:1070-8 | 2013 |
| NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity. Han W, Li H, Cai J, Gleaves LA, Polosukhin VV, Segal BH, Yull FE, Blackwell TS (2013) J Immunol 190:4786-94 | 2013 |
| β-Catenin and CCNs in lung epithelial repair. Lawson WE, Blackwell TS (2013) Am J Physiol Lung Cell Mol Physiol 304:L579-81 | 2013 |
| Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology. Meloche J, Courchesne A, Barrier M, Carter S, Bisserier M, Paulin R, Lauzon-Joset JF, Breuils-Bonnet S, Tremblay É, Biardel S, Racine C, Courture C, Bonnet P, Majka SM, Deshaies Y, Picard F, Provencher S, Bonnet S (2013) J Am Heart Assoc 2:e005157 | 2013 |
| Nitric oxide reduces Cl⁻ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism. Pech V, Thumova M, Dikalov SI, Hummler E, Rossier BC, Harrison DG, Wall SM (2013) Am J Physiol Renal Physiol 304:F1390-7 | 2013 |
| Mechanisms and management of retinopathy of prematurity. Hartnett ME, Penn JS (2013) N Engl J Med 368:1162-3 | 2013 |
| CYP51 structures and structure-based development of novel, pathogen-specific inhibitory scaffolds. Hargrove TY, Kim K, de Nazaré Correia Soeiro M, da Silva CF, Batista DD, Batista MM, Yazlovitskaya EM, Waterman MR, Sulikowski GA, Lepesheva GI (2012) Int J Parasitol Drugs Drug Resist 2:178-186 | 2012 |
| Site-specific AGE modifications in the extracellular matrix: a role for glyoxal in protein damage in diabetes. Voziyan P, Brown KL, Chetyrkin S, Hudson B (2014) Clin Chem Lab Med 52:39-45 | 2014 |
| Identification of myeloid cell subsets in murine lungs using flow cytometry. Zaynagetdinov R, Sherrill TP, Kendall PL, Segal BH, Weller KP, Tighe RM, Blackwell TS (2013) Am J Respir Cell Mol Biol 49:180-9 | 2013 |
| Differential stem- and progenitor-cell trafficking by prostaglandin E2. Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, Breyer RM, Serezani CH, Scadden DT, Guise TA, Srour EF, Pelus LM (2013) Nature 495:365-9 | 2013 |
| N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways. Ouyang M, Lu S, Kim T, Chen CE, Seong J, Leckband DE, Wang F, Reynolds AB, Schwartz MA, Wang Y (2013) Nat Commun 4:1589 | 2013 |
| A General, Enantioselective Synthesis of 1-Azabicyclo[.0]alkane Ring Systems. Senter TJ, Schulte ML, Konkol LC, Wadzinski TE, Lindsley CW (2013) Tetrahedron Lett 54:1645-1648 | 2013 |
| Biomolecular signatures of diabetic wound healing by structural mass spectrometry. Hines KM, Ashfaq S, Davidson JM, Opalenik SR, Wikswo JP, McLean JA (2013) Anal Chem 85:3651-9 | 2013 |
| Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis. Wattacheril J, Seeley EH, Angel P, Chen H, Bowen BP, Lanciault C, Caprioli RM, Abumrad N, Flynn CR (2013) PLoS One 8:e57165 | 2013 |
| miR-153 regulates SNAP-25, synaptic transmission, and neuronal development. Wei C, Thatcher EJ, Olena AF, Cha DJ, Perdigoto AL, Marshall AF, Carter BD, Broadie K, Patton JG (2013) PLoS One 8:e57080 | 2013 |
| Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue. Goudy S, Angel P, Jacobs B, Hill C, Mainini V, Smith AL, Kousa YA, Caprioli R, Prince LS, Baldwin S, Schutte BC (2013) PLoS One 8:e56270 | 2013 |
| Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells. O'Reilly MC, Scott SA, Brown KA, Oguin TH, Thomas PG, Daniels JS, Morrison R, Brown HA, Lindsley CW (2013) J Med Chem 56:2695-9 | 2013 |
| The cell polarity scaffold Lethal Giant Larvae regulates synapse morphology and function. Staples J, Broadie K (2013) J Cell Sci 126:1992-2003 | 2013 |
| Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacology. Gregory KJ, Nguyen ED, Reiff SD, Squire EF, Stauffer SR, Lindsley CW, Meiler J, Conn PJ (2013) Mol Pharmacol 83:991-1006 | 2013 |
| Imatinib: novel treatment of immune-mediated kidney injury. Wallace E, Gewin L (2013) J Am Soc Nephrol 24:694-701 | 2013 |
| The activity of prolactin releasing peptide correlates with its helicity. Deluca SH, Rathmann D, Beck-Sickinger AG, Meiler J (2013) Biopolymers 99:314-25 | 2013 |
| Molecular imaging of retinal disease. Capozzi ME, Gordon AY, Penn JS, Jayagopal A (2013) J Ocul Pharmacol Ther 29:275-86 | 2013 |
| Matrix precoated targets for direct lipid analysis and imaging of tissue. Yang J, Caprioli RM (2013) Anal Chem 85:2907-12 | 2013 |
| Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: the continued optimization of an MLPCN probe molecule. Poslusney MS, Melancon BJ, Gentry PR, Sheffler DJ, Bridges TM, Utley TJ, Daniels JS, Niswender CM, Conn PJ, Lindsley CW, Wood MR (2013) Bioorg Med Chem Lett 23:1860-4 | 2013 |
| The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. Ooi JD, Chang J, O'Sullivan KM, Pedchenko V, Hudson BG, Vandenbark AA, Fugger L, Holdsworth SR, Kitching AR (2013) J Am Soc Nephrol 24:419-31 | 2013 |
| Localized in situ hydrogel-mediated protein digestion and extraction technique for on-tissue analysis. Harris GA, Nicklay JJ, Caprioli RM (2013) Anal Chem 85:2717-23 | 2013 |
| Targeted multiplex imaging mass spectrometry in transmission geometry for subcellular spatial resolution. Thiery-Lavenant G, Zavalin AI, Caprioli RM (2013) J Am Soc Mass Spectrom 24:609-14 | 2013 |
| Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research. Norris JL, Caprioli RM (2013) Chem Rev 113:2309-42 | 2013 |
| IL-17A induces signal transducers and activators of transcription-6-independent airway mucous cell metaplasia. Newcomb DC, Boswell MG, Sherrill TP, Polosukhin VV, Boyd KL, Goleniewska K, Brody SL, Kolls JK, Adler KB, Peebles RS (2013) Am J Respir Cell Mol Biol 48:711-6 | 2013 |
| TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer. Bhola NE, Balko JM, Dugger TC, Kuba MG, Sánchez V, Sanders M, Stanford J, Cook RS, Arteaga CL (2013) J Clin Invest 123:1348-58 | 2013 |
| Proteomic patterns of colonic mucosal tissues delineate Crohn's colitis and ulcerative colitis. Seeley EH, Washington MK, Caprioli RM, M'Koma AE (2013) Proteomics Clin Appl 7:541-9 | 2013 |
| Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. Wikswo JP, Block FE, Cliffel DE, Goodwin CR, Marasco CC, Markov DA, McLean DL, McLean JA, McKenzie JR, Reiserer RS, Samson PC, Schaffer DK, Seale KT, Sherrod SD (2013) IEEE Trans Biomed Eng 60:682-90 | 2013 |
| Grand challenges in interfacing engineering with life sciences and medicine. He B, Baird R, Butera R, Datta A, George S, Hecht B, Hero A, Lazzi G, Lee RC, Liang J, Neuman M, Peng GC, Perreault EJ, Ramasubramanian M, Wang MD, Wikswo J, Yang GZ, Zhang YT (2013) IEEE Trans Biomed Eng 60:589-98 | 2013 |
| Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. Miyabayashi K, Ijichi H, Mohri D, Tada M, Yamamoto K, Asaoka Y, Ikenoue T, Tateishi K, Nakai Y, Isayama H, Morishita Y, Omata M, Moses HL, Koike K (2013) Cancer Res 73:2221-34 | 2013 |
| Amino acids as metabolic substrates during cardiac ischemia. Drake KJ, Sidorov VY, McGuinness OP, Wasserman DH, Wikswo JP (2012) Exp Biol Med (Maywood) 237:1369-78 | 2012 |
| Simultaneous prediction of protein secondary structure and transmembrane spans. Leman JK, Mueller R, Karakas M, Woetzel N, Meiler J (2013) Proteins 81:1127-40 | 2013 |
| A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling. Noetzel MJ, Gregory KJ, Vinson PN, Manka JT, Stauffer SR, Lindsley CW, Niswender CM, Xiang Z, Conn PJ (2013) Mol Pharmacol 83:835-47 | 2013 |
| Patient-derived breast tumor xenografts facilitating personalized cancer therapy. Landis MD, Lehmann BD, Pietenpol JA, Chang JC (2013) Breast Cancer Res 15:201 | 2013 |
| Quantification of transmembrane currents during action potential propagation in the heart. Gray RA, Mashburn DN, Sidorov VY, Wikswo JP (2013) Biophys J 104:268-78 | 2013 |
| Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology. Zhan M, Brooks C, Liu F, Sun L, Dong Z (2013) Kidney Int 83:568-81 | 2013 |
| The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension. Harrison DG (2013) J Am Soc Hypertens 7:68-74 | 2013 |
| β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin. Tanjore H, Degryse AL, Crossno PF, Xu XC, McConaha ME, Jones BR, Polosukhin VV, Bryant AJ, Cheng DS, Newcomb DC, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE (2013) Am J Respir Crit Care Med 187:630-9 | 2013 |
| Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers. Olaru F, Wang XP, Luo W, Ge L, Miner JH, Kleinau S, Geiger XJ, Wasiluk A, Heidet L, Kitching AR, Borza DB (2013) J Immunol 190:1424-32 | 2013 |
| Benchmarking ligand-based virtual High-Throughput Screening with the PubChem database. Butkiewicz M, Lowe EW, Mueller R, Mendenhall JL, Teixeira PL, Weaver CD, Meiler J (2013) Molecules 18:735-56 | 2013 |
| mVps34 deletion in podocytes causes glomerulosclerosis by disrupting intracellular vesicle trafficking. Chen J, Chen MX, Fogo AB, Harris RC, Chen JK (2013) J Am Soc Nephrol 24:198-207 | 2013 |
| Correction to CHOBIMALT: A Cholesterol-Based Detergent. Howell SC, Fraser NJ, Mittal R, Huang L, Travis B, Breyer RM, Sanders CR (2013) Biochemistry 52:445 | 2013 |
| Stem cell therapy for chronic heart failure: an updated appraisal. Maltais S, Joggerst SJ, Hatzopoulos A, DiSalvo TG, Zhao D, Sung HJ, Wang X, Byrne JG, Naftilan AJ (2013) Expert Opin Biol Ther 13:503-16 | 2013 |
| Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation. Pidkovka N, Rao R, Mei S, Gong Y, Harris RC, Wang WH, Capdevila JH (2013) J Biol Chem 288:5223-31 | 2013 |
| Analysis of high-throughput RNAi screening data in identifying genes mediating sensitivity to chemotherapeutic drugs: statistical approaches and perspectives. Ye F, Bauer JA, Pietenpol JA, Shyr Y (2012) BMC Genomics 13 Suppl 8:S3 | 2012 |
| Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin. Zhuang T, Chen Q, Cho MK, Vishnivetskiy SA, Iverson TM, Gurevich VV, Sanders CR (2013) Proc Natl Acad Sci U S A 110:942-7 | 2013 |
| Non-productive DNA damage binding by DNA glycosylase-like protein Mag2 from Schizosaccharomyces pombe. Adhikary S, Cato MC, McGary KL, Rokas A, Eichman BF (2013) DNA Repair (Amst) 12:196-204 | 2013 |
| The best-laid plans. Harris RC (2013) Am J Physiol Renal Physiol 304:F1086-7 | 2013 |
| Mechanisms and management of retinopathy of prematurity. Hartnett ME, Penn JS (2012) N Engl J Med 367:2515-26 | 2012 |
| Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Kropski JA, Lawson WE, Young LR, Blackwell TS (2013) Dis Model Mech 6:9-17 | 2013 |
| The backbone dynamics of the amyloid precursor protein transmembrane helix provides a rationale for the sequential cleavage mechanism of γ-secretase. Pester O, Barrett PJ, Hornburg D, Hornburg P, Pröbstle R, Widmaier S, Kutzner C, Dürrbaum M, Kapurniotu A, Sanders CR, Scharnagl C, Langosch D (2013) J Am Chem Soc 135:1317-29 | 2013 |
| Matrix-assisted laser desorption ionization imaging mass spectrometry: in situ molecular mapping. Angel PM, Caprioli RM (2013) Biochemistry 52:3818-28 | 2013 |
| Chemical modification of the M(1) agonist VU0364572 reveals molecular switches in pharmacology and a bitopic binding mode. Digby GJ, Utley TJ, Lamsal A, Sevel C, Sheffler DJ, Lebois EP, Bridges TM, Wood MR, Niswender CM, Lindsley CW, Conn PJ (2012) ACS Chem Neurosci 3:1025-36 | 2012 |
| The way Wnt works: components and mechanism. Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A, Lee E (2013) Growth Factors 31:1-31 | 2013 |
| Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, Reynolds AB, Williams CS (2012) PLoS One 7:e51205 | 2012 |
| Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs. Lindert S, Stewart PL, Meiler J (2013) Comput Biol Chem 42:1-4 | 2013 |
| Using RosettaLigand for small molecule docking into comparative models. Kaufmann KW, Meiler J (2012) PLoS One 7:e50769 | 2012 |
| Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137: continued optimization of an MLPCN probe molecule. Melancon BJ, Poslusney MS, Gentry PR, Tarr JC, Sheffler DJ, Mattmann ME, Bridges TM, Utley TJ, Daniels JS, Niswender CM, Conn PJ, Lindsley CW, Wood MR (2013) Bioorg Med Chem Lett 23:412-6 | 2013 |
| Upregulated expression of integrin α1 in mesangial cells and integrin α3 and vimentin in podocytes of Col4a3-null (Alport) mice. Steenhard BM, Vanacore R, Friedman D, Zelenchuk A, Stroganova L, Isom K, St John PL, Hudson BG, Abrahamson DR (2012) PLoS One 7:e50745 | 2012 |
| Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. Hood MI, Mortensen BL, Moore JL, Zhang Y, Kehl-Fie TE, Sugitani N, Chazin WJ, Caprioli RM, Skaar EP (2012) PLoS Pathog 8:e1003068 | 2012 |
| Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. Jacobs J, Grum-Tokars V, Zhou Y, Turlington M, Saldanha SA, Chase P, Eggler A, Dawson ES, Baez-Santos YM, Tomar S, Mielech AM, Baker SC, Lindsley CW, Hodder P, Mesecar A, Stauffer SR (2013) J Med Chem 56:534-46 | 2013 |
| Assessment of renal function in mice with unilateral ureteral obstruction using 99mTc-MAG3 dynamic scintigraphy. Tantawy MN, Jiang R, Wang F, Takahashi K, Peterson TE, Zemel D, Hao CM, Fujita H, Harris RC, Quarles CC, Takahashi T (2012) BMC Nephrol 13:168 | 2012 |
| Dual blockade of HER2 in HER2-overexpressing tumor cells does not completely eliminate HER3 function. Garrett JT, Sutton CR, Kuba MG, Cook RS, Arteaga CL (2013) Clin Cancer Res 19:610-9 | 2013 |
| Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Müller II, Melville DB, Tanwar V, Rybski WM, Mukherjee A, Shoemaker MB, Wang WD, Schoenhard JA, Roden DM, Darbar D, Knapik EW, Hatzopoulos AK (2013) Dis Model Mech 6:332-41 | 2013 |
| Development of an in vivo active, dual EP1 and EP3 selective antagonist based on a novel acyl sulfonamide bioisostere. Downey JD, Saleh SA, Bridges TM, Morrison RD, Daniels JS, Lindsley CW, Breyer RM (2013) Bioorg Med Chem Lett 23:37-41 | 2013 |
| Endoplasmic reticulum stress as a pro-fibrotic stimulus. Tanjore H, Lawson WE, Blackwell TS (2013) Biochim Biophys Acta 1832:940-7 | 2013 |
| Further exploration of M₁ allosteric agonists: subtle structural changes abolish M₁ allosteric agonism and result in pan-mAChR orthosteric antagonism. Sheffler DJ, Sevel C, Le U, Lovell KM, Tarr JC, Carrington SJ, Cho HP, Digby GJ, Niswender CM, Conn PJ, Hopkins CR, Wood MR, Lindsley CW (2013) Bioorg Med Chem Lett 23:223-7 | 2013 |
| An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1. Yang T, Smith JA, Leake BF, Sanders CR, Meiler J, Roden DM (2013) Mol Pharmacol 83:481-9 | 2013 |
| Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence. Liu Y, Hawkins OE, Su Y, Vilgelm AE, Sobolik T, Thu YM, Kantrow S, Splittgerber RC, Short S, Amiri KI, Ecsedy JA, Sosman JA, Kelley MC, Richmond A (2013) EMBO Mol Med 5:149-66 | 2013 |
| Discovery of a selective M₄ positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia. Le U, Melancon BJ, Bridges TM, Vinson PN, Utley TJ, Lamsal A, Rodriguez AL, Venable D, Sheffler DJ, Jones CK, Blobaum AL, Wood MR, Daniels JS, Conn PJ, Niswender CM, Lindsley CW, Hopkins CR (2013) Bioorg Med Chem Lett 23:346-50 | 2013 |
| Targeting selective activation of M(1) for the treatment of Alzheimer's disease: further chemical optimization and pharmacological characterization of the M(1) positive allosteric modulator ML169. Tarr JC, Turlington ML, Reid PR, Utley TJ, Sheffler DJ, Cho HP, Klar R, Pancani T, Klein MT, Bridges TM, Morrison RD, Blobaum AL, Xiang Z, Daniels JS, Niswender CM, Conn PJ, Wood MR, Lindsley CW (2012) ACS Chem Neurosci 3:884-95 | 2012 |
| BCL::Score--knowledge based energy potentials for ranking protein models represented by idealized secondary structure elements. Woetzel N, Karakaş M, Staritzbichler R, Müller R, Weiner BE, Meiler J (2012) PLoS One 7:e49242 | 2012 |
| BCL::Fold--de novo prediction of complex and large protein topologies by assembly of secondary structure elements. Karakaş M, Woetzel N, Staritzbichler R, Alexander N, Weiner BE, Meiler J (2012) PLoS One 7:e49240 | 2012 |
| Deleting the TGF-β receptor attenuates acute proximal tubule injury. Gewin L, Vadivelu S, Neelisetty S, Srichai MB, Paueksakon P, Pozzi A, Harris RC, Zent R (2012) J Am Soc Nephrol 23:2001-11 | 2012 |
| Direct imaging of single cells and tissue at sub-cellular spatial resolution using transmission geometry MALDI MS. Zavalin A, Todd EM, Rawhouser PD, Yang J, Norris JL, Caprioli RM (2012) J Mass Spectrom 47:1473-81 | 2012 |
| A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling. Dani N, Nahm M, Lee S, Broadie K (2012) PLoS Genet 8:e1003031 | 2012 |
| CSF-1 signaling mediates recovery from acute kidney injury. Zhang MZ, Yao B, Yang S, Jiang L, Wang S, Fan X, Yin H, Wong K, Miyazawa T, Chen J, Chang I, Singh A, Harris RC (2012) J Clin Invest 122:4519-32 | 2012 |
| Discovery and SAR of a novel series of non-MPEP site mGlu₅ PAMs based on an aryl glycine sulfonamide scaffold. Rodriguez AL, Zhou Y, Williams R, Weaver CD, Vinson PN, Dawson ES, Steckler T, Lavreysen H, Mackie C, Bartolomé JM, Macdonald GJ, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Stauffer SR (2012) Bioorg Med Chem Lett 22:7388-92 | 2012 |
| Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity. Rook JM, Noetzel MJ, Pouliot WA, Bridges TM, Vinson PN, Cho HP, Zhou Y, Gogliotti RD, Manka JT, Gregory KJ, Stauffer SR, Dudek FE, Xiang Z, Niswender CM, Daniels JS, Jones CK, Lindsley CW, Conn PJ (2013) Biol Psychiatry 73:501-9 | 2013 |
| Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli. Hodgin JB, Nair V, Zhang H, Randolph A, Harris RC, Nelson RG, Weil EJ, Cavalcoli JD, Patel JM, Brosius FC, Kretzler M (2013) Diabetes 62:299-308 | 2013 |
| Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial. Traverse JH, Henry TD, Pepine CJ, Willerson JT, Zhao DX, Ellis SG, Forder JR, Anderson RD, Hatzopoulos AK, Penn MS, Perin EC, Chambers J, Baran KW, Raveendran G, Lambert C, Lerman A, Simon DI, Vaughan DE, Lai D, Gee AP, Taylor DA, Cogle CR, Thomas JD, Olson RE, Bowman S, Francescon J, Geither C, Handberg E, Kappenman C, Westbrook L, Piller LB, Simpson LM, Baraniuk S, Loghin C, Aguilar D, Richman S, Zierold C, Spoon DB, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD, Cardiovascular Cell Therapy Research Network (CCTRN) (2012) JAMA 308:2380-9 | 2012 |
| Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films. Zachman AL, Page JM, Prabhakar G, Guelcher SA, Sung HJ (2013) Acta Biomater 9:4964-75 | 2013 |
| Bioluminescence imaging of NADPH oxidase activity in different animal models. Han W, Li H, Segal BH, Blackwell TS (2012) J Vis Exp : | 2012 |
| Biomimetic synthesis and biological evaluation of Aplidiopsamine A. Panarese JD, Lindsley CW (2012) Org Lett 14:5808-10 | 2012 |
| Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry. Jodoin JN, Shboul M, Sitaram P, Zein-Sabatto H, Reversade B, Lee E, Lee LA (2012) Mol Biol Cell 23:4713-24 | 2012 |
| Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12. Schmidt P, Ritscher L, Dong EN, Hermsdorf T, Cöster M, Wittkopf D, Meiler J, Schöneberg T (2013) Mol Pharmacol 83:256-66 | 2013 |
| Conformation of receptor-bound visual arrestin. Kim M, Vishnivetskiy SA, Van Eps N, Alexander NS, Cleghorn WM, Zhan X, Hanson SM, Morizumi T, Ernst OP, Meiler J, Gurevich VV, Hubbell WL (2012) Proc Natl Acad Sci U S A 109:18407-12 | 2012 |
| Extracellular loop II modulates GTP sensitivity of the prostaglandin EP3 receptor. Natarajan C, Hata AN, Hamm HE, Zent R, Breyer RM (2013) Mol Pharmacol 83:206-16 | 2013 |
| Recent advances in the structural mechanisms of DNA glycosylases. Brooks SC, Adhikary S, Rubinson EH, Eichman BF (2013) Biochim Biophys Acta 1834:247-71 | 2013 |
| Inactivation of the E-prostanoid 3 receptor attenuates the angiotensin II pressor response via decreasing arterial contractility. Chen L, Miao Y, Zhang Y, Dou D, Liu L, Tian X, Yang G, Pu D, Zhang X, Kang J, Gao Y, Wang S, Breyer MD, Wang N, Zhu Y, Huang Y, Breyer RM, Guan Y (2012) Arterioscler Thromb Vasc Biol 32:3024-32 | 2012 |
| Interstitial mononuclear infiltrates in murine α3(IV)-NC1-induced nephropathy: harbingers of renal failure? Borza DB, Fogo AB (2012) Kidney Int 82:1033-4; author reply 1034 | 2012 |
| Synthesis and biological characterization of a series of novel diaryl amide M₁ antagonists. Poslusney MS, Sevel C, Utley TJ, Bridges TM, Morrison RD, Kett NR, Sheffler DJ, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR (2012) Bioorg Med Chem Lett 22:6923-8 | 2012 |
| VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity. Rao M, Song W, Jiang A, Shyr Y, Lev S, Greenstein D, Brantley-Sieders D, Chen J (2012) PLoS One 7:e46281 | 2012 |
| Thymosin β4 mobilizes mesothelial cells for blood vessel repair. Shelton EL, Bader DM (2012) Ann N Y Acad Sci 1269:125-30 | 2012 |
| The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome. Young LR, Gulleman PM, Bridges JP, Weaver TE, Deutsch GH, Blackwell TS, McCormack FX (2012) Am J Respir Crit Care Med 186:1014-24 | 2012 |
| Established and novel methods of interrogating two-dimensional cell migration. Ashby WJ, Zijlstra A (2012) Integr Biol (Camb) 4:1338-50 | 2012 |
| Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias. Potet F, Lorinc AN, Chaigne S, Hopkins CR, Venkataraman R, Stepanovic SZ, Lewis LM, Days E, Sidorov VY, Engers DW, Zou B, Afshartous D, George AL, Campbell CM, Balser JR, Li M, Baudenbacher FJ, Lindsley CW, Weaver CD, Kupershmidt S (2012) J Biol Chem 287:39613-25 | 2012 |
| Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53. Eischen CM, Boyd K (2012) PLoS One 7:e46148 | 2012 |
| Local breast cancer spatial patterning: a tool for community health resource allocation to address local disparities in breast cancer mortality. Brantley-Sieders DM, Fan KH, Deming-Halverson SL, Shyr Y, Cook RS (2012) PLoS One 7:e45238 | 2012 |
| Drosophila Ninjurin A induces nonapoptotic cell death. Broderick S, Wang X, Simms N, Page-McCaw A (2012) PLoS One 7:e44567 | 2012 |
| Total synthesis and biological evaluation of phidianidines A and B uncovers unique pharmacological profiles at CNS targets. Brogan JT, Stoops SL, Lindsley CW (2012) ACS Chem Neurosci 3:658-64 | 2012 |
| Imaging the clear cell renal cell carcinoma proteome. Morgan TM, Seeley EH, Fadare O, Caprioli RM, Clark PE (2013) J Urol 189:1097-103 | 2013 |
| EP1 disruption attenuates end-organ damage in a mouse model of hypertension. Bartlett CS, Boyd KL, Harris RC, Zent R, Breyer RM (2012) Hypertension 60:1184-91 | 2012 |
| eNOS deficiency predisposes podocytes to injury in diabetes. Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A (2012) J Am Soc Nephrol 23:1810-23 | 2012 |
| Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover. Manka JT, Vinson PN, Gregory KJ, Zhou Y, Williams R, Gogi K, Days E, Jadhav S, Herman EJ, Lavreysen H, Mackie C, Bartolomé JM, Macdonald GJ, Steckler T, Daniels JS, Weaver CD, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Stauffer SR (2012) Bioorg Med Chem Lett 22:6481-5 | 2012 |
| Connecting the segments. Zent R, Pozzi A (2012) J Am Soc Nephrol 23:1603-5 | 2012 |
| Nonmuscle myosin II regulation of lung epithelial morphology. Plosa EJ, Gooding KA, Zent R, Prince LS (2012) Dev Dyn 241:1770-81 | 2012 |
| Intraductal injection of LPS as a mouse model of mastitis: signaling visualized via an NF-κB reporter transgenic. Barham W, Sherrill T, Connelly L, Blackwell TS, Yull FE (2012) J Vis Exp :e4030 | 2012 |
| Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis. Hoshino D, Jourquin J, Emmons SW, Miller T, Goldgof M, Costello K, Tyson DR, Brown B, Lu Y, Prasad NK, Zhang B, Mills GB, Yarbrough WG, Quaranta V, Seiki M, Weaver AM (2012) Sci Signal 5:ra66 | 2012 |
| A dual-column solid phase extraction strategy for online collection and preparation of continuously flowing effluent streams for mass spectrometry. Enders JR, Marasco CC, Wikswo JP, McLean JA (2012) Anal Chem 84:8467-74 | 2012 |
| Targeting mutant p53 in human tumors. Lehmann BD, Pietenpol JA (2012) J Clin Oncol 30:3648-50 | 2012 |
| Thick-tissue bioreactor as a platform for long-term organotypic culture and drug delivery. Markov DA, Lu JQ, Samson PC, Wikswo JP, McCawley LJ (2012) Lab Chip 12:4560-8 | 2012 |
| Targeting BRCA1 localization to augment breast tumor sensitivity to poly(ADP-Ribose) polymerase inhibition. Yang ES, Nowsheen S, Rahman MA, Cook RS, Xia F (2012) Cancer Res 72:5547-55 | 2012 |
| The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. Ooi JD, Chang J, Hickey MJ, Borza DB, Fugger L, Holdsworth SR, Kitching AR (2012) Proc Natl Acad Sci U S A 109:E2615-24 | 2012 |
| Pro-angiogenic and anti-inflammatory regulation by functional peptides loaded in polymeric implants for soft tissue regeneration. Zachman AL, Crowder SW, Ortiz O, Zienkiewicz KJ, Bronikowski CM, Yu SS, Giorgio TD, Guelcher SA, Kohn J, Sung HJ (2013) Tissue Eng Part A 19:437-47 | 2013 |
| Jelly Belly trans-synaptic signaling to anaplastic lymphoma kinase regulates neurotransmission strength and synapse architecture. Rohrbough J, Kent KS, Broadie K, Weiss JB (2013) Dev Neurobiol 73:189-208 | 2013 |
| Magnetically attachable stencils and the non-destructive analysis of the contribution made by the underlying matrix to cell migration. Ashby WJ, Wikswo JP, Zijlstra A (2012) Biomaterials 33:8189-203 | 2012 |
| Comprehensive timeline of mesodermal development in the quail small intestine. Thomason RT, Bader DM, Winters NI (2012) Dev Dyn 241:1678-94 | 2012 |
| Structural biology of replication initiation factor Mcm10. Du W, Stauffer ME, Eichman BF (2012) Subcell Biochem 62:197-216 | 2012 |
| Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity. Kocalis HE, Turney MK, Printz RL, Laryea GN, Muglia LJ, Davies SS, Stanwood GD, McGuinness OP, Niswender KD (2012) PLoS One 7:e42981 | 2012 |
| Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease. Shi J, Wang Q, Johansson JU, Liang X, Woodling NS, Priyam P, Loui TM, Merchant M, Breyer RM, Montine TJ, Andreasson K (2012) Ann Neurol 72:788-98 | 2012 |
| Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Mattmann ME, Yu H, Lin Z, Xu K, Huang X, Long S, Wu M, McManus OB, Engers DW, Le UM, Li M, Lindsley CW, Hopkins CR (2012) Bioorg Med Chem Lett 22:5936-41 | 2012 |
| Conditional control of gene function by an invertible gene trap in zebrafish. Ni TT, Lu J, Zhu M, Maddison LA, Boyd KL, Huskey L, Ju B, Hesselson D, Zhong TP, Page-McCaw PS, Stainier DY, Chen W (2012) Proc Natl Acad Sci U S A 109:15389-94 | 2012 |
| BCL::EMAS--enantioselective molecular asymmetry descriptor for 3D-QSAR. Sliwoski G, Lowe EW, Butkiewicz M, Meiler J (2012) Molecules 17:9971-89 | 2012 |
| Identification of novel bioactive aldehyde-modified phosphatidylethanolamines formed by lipid peroxidation. Guo L, Chen Z, Amarnath V, Davies SS (2012) Free Radic Biol Med 53:1226-38 | 2012 |
| Monoclonal antibodies to DIPA: a novel binding partner of p120-catenin isoform 1. Markham NO, Cooper T, Goff M, Gribben EM, Carnahan RH, Reynolds AB (2012) Hybridoma (Larchmt) 31:246-54 | 2012 |
| Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis. Shi M, Pedchenko V, Greer BH, Van Horn WD, Santoro SA, Sanders CR, Hudson BG, Eichman BF, Zent R, Pozzi A (2012) J Biol Chem 287:35139-52 | 2012 |
| Turn off the IDO: will clinical trials be successful? Novitskiy SV, Moses HL (2012) Cancer Discov 2:673-5 | 2012 |
| Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data. Tyson DR, Garbett SP, Frick PL, Quaranta V (2012) Nat Methods 9:923-8 | 2012 |
| TNBCtype: A Subtyping Tool for Triple-Negative Breast Cancer. Chen X, Li J, Gray WH, Lehmann BD, Bauer JA, Shyr Y, Pietenpol JA (2012) Cancer Inform 11:147-56 | 2012 |
| Biocompatibility and chemical reaction kinetics of injectable, settable polyurethane/allograft bone biocomposites. Page JM, Prieto EM, Dumas JE, Zienkiewicz KJ, Wenke JC, Brown-Baer P, Guelcher SA (2012) Acta Biomater 8:4405-16 | 2012 |
| The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions. Raghuwanshi SK, Su Y, Singh V, Haynes K, Richmond A, Richardson RM (2012) J Immunol 189:2824-32 | 2012 |
| β1 integrin NPXY motifs regulate kidney collecting-duct development and maintenance by induced-fit interactions with cytosolic proteins. Mathew S, Lu Z, Palamuttam RJ, Mernaugh G, Hadziselimovic A, Chen J, Bulus N, Gewin LS, Voehler M, Meves A, Ballestrem C, Fässler R, Pozzi A, Sanders CR, Zent R (2012) Mol Cell Biol 32:4080-91 | 2012 |
| Targeted multiplex imaging mass spectrometry with single chain fragment variable (scfv) recombinant antibodies. Thiery G, Mernaugh RL, Yan H, Spraggins JM, Yang J, Parl FF, Caprioli RM (2012) J Am Soc Mass Spectrom 23:1689-96 | 2012 |
| Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships. Gregory KJ, Noetzel MJ, Rook JM, Vinson PN, Stauffer SR, Rodriguez AL, Emmitte KA, Zhou Y, Chun AC, Felts AS, Chauder BA, Lindsley CW, Niswender CM, Conn PJ (2012) Mol Pharmacol 82:860-75 | 2012 |
| Membrane-bound myo1c powers asymmetric motility of actin filaments. Pyrpassopoulos S, Feeser EA, Mazerik JN, Tyska MJ, Ostap EM (2012) Curr Biol 22:1688-92 | 2012 |
| Metabolic multianalyte microphysiometry reveals extracellular acidosis is an essential mediator of neuronal preconditioning. McKenzie JR, Palubinsky AM, Brown JE, McLaughlin B, Cliffel DE (2012) ACS Chem Neurosci 3:510-8 | 2012 |
| Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis. Bhave G, Cummings CF, Vanacore RM, Kumagai-Cresse C, Ero-Tolliver IA, Rafi M, Kang JS, Pedchenko V, Fessler LI, Fessler JH, Hudson BG (2012) Nat Chem Biol 8:784-90 | 2012 |
| INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma. Yang J, Kantrow S, Sai J, Hawkins OE, Boothby M, Ayers GD, Young ED, Demicco EG, Lazar AJ, Lev D, Richmond A (2012) Cancer Res 72:4682-95 | 2012 |
| Response of bone marrow stromal cells to graded co-electrospun scaffolds and its implications for engineering the ligament-bone interface. Samavedi S, Guelcher SA, Goldstein AS, Whittington AR (2012) Biomaterials 33:7727-35 | 2012 |
| How does TGF-β mediate tubulointerstitial fibrosis? Gewin L, Zent R (2012) Semin Nephrol 32:228-35 | 2012 |
| Effects of cancer-associated EPHA3 mutations on lung cancer. Zhuang G, Song W, Amato K, Hwang Y, Lee K, Boothby M, Ye F, Guo Y, Shyr Y, Lin L, Carbone DP, Brantley-Sieders DM, Chen J (2012) J Natl Cancer Inst 104:1182-97 | 2012 |
| Ready…aim…fire into the lumen: a new role for enterocyte microvilli in gut host defense. Shifrin DA, Tyska MJ (2012) Gut Microbes 3:460-2 | 2012 |
| Synthesis and Biological Evaluation of Cremastrine and an Unnatural Analogue. Hahn KN, Fadeyi OO, Cho HP, Lindsley CW (2012) Tetrahedron Lett 53:3577-3580 | 2012 |
| Bioactive aldehyde-modified phosphatidylethanolamines. Guo L, Davies SS (2013) Biochimie 95:74-8 | 2013 |
| Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice. Campbell JP, Karolak MR, Ma Y, Perrien DS, Masood-Campbell SK, Penner NL, Munoz SA, Zijlstra A, Yang X, Sterling JA, Elefteriou F (2012) PLoS Biol 10:e1001363 | 2012 |
| Decreased viability and absence-like epilepsy in mice lacking or deficient in the GABAA receptor α1 subunit. Arain FM, Boyd KL, Gallagher MJ (2012) Epilepsia 53:e161-5 | 2012 |
| Association of high blood pressure with renal insufficiency: role of albuminuria, from NHANES, 1999-2006. Yan P, Zhu X, Li H, Shrubsole MJ, Shi H, Zhang MZ, Harris RC, Hao CM, Dai Q (2012) PLoS One 7:e37837 | 2012 |
| Integrity and function of the Saccharomyces cerevisiae spindle pole body depends on connections between the membrane proteins Ndc1, Rtn1, and Yop1. Casey AK, Dawson TR, Chen J, Friederichs JM, Jaspersen SL, Wente SR (2012) Genetics 192:441-55 | 2012 |
| Viral acute lower respiratory infections impair CD8+ T cells through PD-1. Erickson JJ, Gilchuk P, Hastings AK, Tollefson SJ, Johnson M, Downing MB, Boyd KL, Johnson JE, Kim AS, Joyce S, Williams JV (2012) J Clin Invest 122:2967-82 | 2012 |
| The contribution of age structure to cell population responses to targeted therapeutics. Gabriel P, Garbett SP, Quaranta V, Tyson DR, Webb GF (2012) J Theor Biol 311:19-27 | 2012 |
| Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor. Cheung YY, Yu H, Xu K, Zou B, Wu M, McManus OB, Li M, Lindsley CW, Hopkins CR (2012) J Med Chem 55:6975-9 | 2012 |
| Podocyte ACE2 protects against diabetic nephropathy. Harris RC (2012) Kidney Int 82:255-6 | 2012 |
| Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis. Hao J, Sawyer DB, Hatzopoulos AK, Hong CC (2011) Recent Pat Regen Med 1:263-274 | 2011 |
| Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice. Howard C, Tao S, Yang HC, Fogo AB, Woodgett JR, Harris RC, Rao R (2012) Kidney Int 82:1000-9 | 2012 |
| Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Cheng H, Wang H, Fan X, Paueksakon P, Harris RC (2012) Kidney Int 82:1176-83 | 2012 |
| Y95 and E444 interaction required for high-affinity S-citalopram binding in the human serotonin transporter. Combs S, Kaufmann K, Field JR, Blakely RD, Meiler J (2011) ACS Chem Neurosci 2:75-81 | 2011 |
| Ligand-mimicking receptor variant discloses binding and activation mode of prolactin-releasing peptide. Rathmann D, Lindner D, DeLuca SH, Kaufmann KW, Meiler J, Beck-Sickinger AG (2012) J Biol Chem 287:32181-94 | 2012 |
| Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK (2012) Proc Natl Acad Sci U S A 109:12105-10 | 2012 |
| CD98 increases renal epithelial cell proliferation by activating MAPKs. Bulus N, Feral C, Pozzi A, Zent R (2012) PLoS One 7:e40026 | 2012 |
| Identification of a novel developmental mechanism in the generation of mesothelia. Winters NI, Thomason RT, Bader DM (2012) Development 139:2926-34 | 2012 |
| Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis. Sitaram P, Anderson MA, Jodoin JN, Lee E, Lee LA (2012) Development 139:2945-54 | 2012 |
| Novel radiosensitizing anticancer therapeutics. Linkous AG, Yazlovitskaya EM (2012) Anticancer Res 32:2487-99 | 2012 |
| Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012. Melancon BJ, Utley TJ, Sevel C, Mattmann ME, Cheung YY, Bridges TM, Morrison RD, Sheffler DJ, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR (2012) Bioorg Med Chem Lett 22:5035-40 | 2012 |
| Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk. Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL (2012) Breast Cancer Res 14:R98 | 2012 |
| Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor. Salovich JM, Vinson PN, Sheffler DJ, Lamsal A, Utley TJ, Blobaum AL, Bridges TM, Le U, Jones CK, Wood MR, Daniels JS, Conn PJ, Niswender CM, Lindsley CW, Hopkins CR (2012) Bioorg Med Chem Lett 22:5084-8 | 2012 |
| Research resource: dkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to aggregate research resources generated by multiple research consortia. McKenna NJ, Howard CL, Aufiero M, Easton-Marks J, Steffen DL, Becnel LB, Magnuson MA, McIndoe RA, Cartailler JP (2012) Mol Endocrinol 26:1675-81 | 2012 |
| Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism. Buehler PW, Baek JH, Lisk C, Connor I, Sullivan T, Kominsky D, Majka S, Stenmark KR, Nozik-Grayck E, Bonaventura J, Irwin DC (2012) Am J Physiol Lung Cell Mol Physiol 303:L312-26 | 2012 |
| Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe. Delpire E, Baranczak A, Waterson AG, Kim K, Kett N, Morrison RD, Daniels JS, Weaver CD, Lindsley CW (2012) Bioorg Med Chem Lett 22:4532-5 | 2012 |
| Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models. Digby GJ, Noetzel MJ, Bubser M, Utley TJ, Walker AG, Byun NE, Lebois EP, Xiang Z, Sheffler DJ, Cho HP, Davis AA, Nemirovsky NE, Mennenga SE, Camp BW, Bimonte-Nelson HA, Bode J, Italiano K, Morrison R, Daniels JS, Niswender CM, Olive MF, Lindsley CW, Jones CK, Conn PJ (2012) J Neurosci 32:8532-44 | 2012 |
| Real-time pharmacy surveillance and clinical decision support to reduce adverse drug events in acute kidney injury: a randomized, controlled trial. McCoy AB, Cox ZL, Neal EB, Waitman LR, Peterson NB, Bhave G, Siew ED, Danciu I, Lewis JB, Peterson JF (2012) Appl Clin Inform 3:221-238 | 2012 |
| Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical-sized segmental defect in rat femora. Yoshii T, Hafeman AE, Esparza JM, Okawa A, Gutierrez G, Guelcher SA (2014) J Tissue Eng Regen Med 8:589-95 | 2014 |
| The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5. Morrison RD, Blobaum AL, Byers FW, Santomango TS, Bridges TM, Stec D, Brewer KA, Sanchez-Ponce R, Corlew MM, Rush R, Felts AS, Manka J, Bates BS, Venable DF, Rodriguez AL, Jones CK, Niswender CM, Conn PJ, Lindsley CW, Emmitte KA, Daniels JS (2012) Drug Metab Dispos 40:1834-45 | 2012 |
| Selective mode of action of guanidine-containing non-peptides at human NPFF receptors. Findeisen M, Würker C, Rathmann D, Meier R, Meiler J, Olsson R, Beck-Sickinger AG (2012) J Med Chem 55:6124-36 | 2012 |
| Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice. McCurdy CE, Schenk S, Holliday MJ, Philp A, Houck JA, Patsouris D, MacLean PS, Majka SM, Klemm DJ, Friedman JE (2012) Diabetes 61:2495-505 | 2012 |
| Intrarenal dopamine inhibits progression of diabetic nephropathy. Zhang MZ, Yao B, Yang S, Yang H, Wang S, Fan X, Yin H, Fogo AB, Moeckel GW, Harris RC (2012) Diabetes 61:2575-84 | 2012 |
| Matrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome. Siller SS, Broadie K (2012) Neural Plast 2012:124548 | 2012 |
| Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties. Novitskiy SV, Pickup MW, Chytil A, Polosukhina D, Owens P, Moses HL (2012) J Leukoc Biol 92:641-51 | 2012 |
| Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance. Balko JM, Cook RS, Vaught DB, Kuba MG, Miller TW, Bhola NE, Sanders ME, Granja-Ingram NM, Smith JJ, Meszoely IM, Salter J, Dowsett M, Stemke-Hale K, González-Angulo AM, Mills GB, Pinto JA, Gómez HL, Arteaga CL (2012) Nat Med 18:1052-9 | 2012 |
| Purification and characterization of the human γ-secretase activating protein. Deatherage CL, Hadziselimovic A, Sanders CR (2012) Biochemistry 51:5153-9 | 2012 |
| Studies of the T-cell angiotensin receptor using cre-lox technology: an unan-T-cellpated result. Harrison DG, Guzik TJ (2012) Circ Res 110:1543-5 | 2012 |
| The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol. Barrett PJ, Song Y, Van Horn WD, Hustedt EJ, Schafer JM, Hadziselimovic A, Beel AJ, Sanders CR (2012) Science 336:1168-71 | 2012 |
| The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Hahn AS, Kaufmann JK, Wies E, Naschberger E, Panteleev-Ivlev J, Schmidt K, Holzer A, Schmidt M, Chen J, König S, Ensser A, Myoung J, Brockmeyer NH, Stürzl M, Fleckenstein B, Neipel F (2012) Nat Med 18:961-6 | 2012 |
| SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2(Akita) diabetic mice. Fujita H, Fujishima H, Takahashi K, Sato T, Shimizu T, Morii T, Shimizu T, Shirasawa T, Qi Z, Breyer MD, Harris RC, Yamada Y, Takahashi T (2012) Metabolism 61:1714-24 | 2012 |
| Haploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments. McLaughlin B, Buendia MA, Saborido TP, Palubinsky AM, Stankowski JN, Stanwood GD (2012) PLoS One 7:e36340 | 2012 |
| Iterative experimental and virtual high-throughput screening identifies metabotropic glutamate receptor subtype 4 positive allosteric modulators. Mueller R, Dawson ES, Niswender CM, Butkiewicz M, Hopkins CR, Weaver CD, Lindsley CW, Conn PJ, Meiler J (2012) J Mol Model 18:4437-46 | 2012 |
| Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis. Zhou W, Dowell DR, Huckabee MM, Newcomb DC, Boswell MG, Goleniewska K, Lotz MT, Toki S, Yin H, Yao S, Natarajan C, Wu P, Sriram S, Breyer RM, Fitzgerald GA, Peebles RS (2012) PLoS One 7:e33518 | 2012 |
| Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases. Chen J (2012) Adv Cancer Res 114:1-20 | 2012 |
| Vascular inflammatory cells in hypertension. Harrison DG, Marvar PJ, Titze JM (2012) Front Physiol 3:128 | 2012 |
| Metabolic discrimination of select list agents by monitoring cellular responses in a multianalyte microphysiometer. Eklund SE, Thompson RG, Snider RM, Carney CK, Wright DW, Wikswo J, Cliffel DE (2009) Sensors (Basel) 9:2117-33 | 2009 |
| The role of central nervous system development in late-onset neurodegenerative disorders. Palubinsky AM, Martin JA, McLaughlin B (2012) Dev Neurosci 34:129-39 | 2012 |
| Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy. Dees E, Miller PM, Moynihan KL, Pooley RD, Hunt RP, Galindo CL, Rottman JN, Bader DM (2012) Dis Model Mech 5:468-80 | 2012 |
| Increased expression of SVCT2 in a new mouse model raises ascorbic acid in tissues and protects against paraquat-induced oxidative damage in lung. Harrison FE, Best JL, Meredith ME, Gamlin CR, Borza DB, May JM, May JM (2012) PLoS One 7:e35623 | 2012 |
| Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians. Ma X, Beeghly-Fadiel A, Lu W, Shi J, Xiang YB, Cai Q, Shen H, Shen CY, Ren Z, Matsuo K, Khoo US, Iwasaki M, Long J, Zhang B, Ji BT, Zheng Y, Wang W, Hu Z, Liu Y, Wu PE, Shieh YL, Wang S, Xie X, Ito H, Kasuga Y, Chan KY, Iwata H, Tsugane S, Gao YT, Shu XO, Moses HL, Zheng W (2012) Cancer Epidemiol Biomarkers Prev 21:1176-84 | 2012 |
| Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials. Lovly CM, Dahlman KB, Fohn LE, Su Z, Dias-Santagata D, Hicks DJ, Hucks D, Berry E, Terry C, Duke M, Su Y, Sobolik-Delmaire T, Richmond A, Kelley MC, Vnencak-Jones CL, Iafrate AJ, Sosman J, Pao W (2012) PLoS One 7:e35309 | 2012 |
| The mammalian kidney. Zent R, Harris R (2012) Exp Cell Res 318:v | 2012 |
| Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects. Yang R, Shi J, Byeon IJ, Ahn J, Sheehan JH, Meiler J, Gronenborn AM, Aiken C (2012) Retrovirology 9:30 | 2012 |
| Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis. Uzhachenko R, Issaeva N, Boyd K, Ivanov SV, Carbone DP, Ivanova AV (2012) J Pathol 227:456-69 | 2012 |
| Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies. Hoshino D, Koshikawa N, Suzuki T, Quaranta V, Weaver AM, Seiki M, Ichikawa K (2012) PLoS Comput Biol 8:e1002479 | 2012 |
| Eicosanoid receptor subtype-mediated opposing regulation of TLR-stimulated expression of astrocyte glial-derived neurotrophic factor. Li X, Cudaback E, Breyer RM, Montine KS, Keene CD, Montine TJ (2012) FASEB J 26:3075-83 | 2012 |
| Kim-1/Tim-1 and immune cells: shifting sands. Ichimura T, Brooks CR, Bonventre JV (2012) Kidney Int 81:809-11 | 2012 |
| Cleavage of PGRP-LC receptor in the Drosophila IMD pathway in response to live bacterial infection in S2 cells. Schmidt RL, Rinaldo FM, Hesse SE, Hamada M, Ortiz Z, Beleford DT, Page-McCaw A, Platt JL, Tang AH (2011) Self Nonself 2:125-141 | 2011 |
| Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. Hatoum IJ, Stylopoulos N, Vanhoose AM, Boyd KL, Yin DP, Ellacott KL, Ma LL, Blaszczyk K, Keogh JM, Cone RD, Farooqi IS, Kaplan LM (2012) J Clin Endocrinol Metab 97:E1023-31 | 2012 |
| A membrane fusion protein αSNAP is a novel regulator of epithelial apical junctions. Naydenov NG, Brown B, Harris G, Dohn MR, Morales VM, Baranwal S, Reynolds AB, Ivanov AI (2012) PLoS One 7:e34320 | 2012 |
| Real-time visualization and quantitation of vascular permeability in vivo: implications for drug delivery. Pink DB, Schulte W, Parseghian MH, Zijlstra A, Lewis JD (2012) PLoS One 7:e33760 | 2012 |
| Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M (2012) J Exp Med 209:713-28 | 2012 |
| Generation of a conditional allele for the mouse endothelial nitric oxide synthase gene. Jiang R, Wang S, Takahashi K, Fujita H, Fruci CR, Breyer MD, Harris RC, Takahashi T (2012) Genesis 50:685-92 | 2012 |
| p120-catenin is essential for terminal end bud function and mammary morphogenesis. Kurley SJ, Bierie B, Carnahan RH, Lobdell NA, Davis MA, Hofmann I, Moses HL, Muller WJ, Reynolds AB (2012) Development 139:1754-64 | 2012 |
| HER3 is required for HER2-induced preneoplastic changes to the breast epithelium and tumor formation. Vaught DB, Stanford JC, Young C, Hicks DJ, Wheeler F, Rinehart C, Sánchez V, Koland J, Muller WJ, Arteaga CL, Cook RS (2012) Cancer Res 72:2672-82 | 2012 |
| Injectable reactive biocomposites for bone healing in critical-size rabbit calvarial defects. Dumas JE, BrownBaer PB, Prieto EM, Guda T, Hale RG, Wenke JC, Guelcher SA (2012) Biomed Mater 7:024112 | 2012 |
| Role of the renin-angiotensin system in the pathogenesis of intimal hyperplasia: therapeutic potential for prevention of vein graft failure? Osgood MJ, Harrison DG, Sexton KW, Hocking KM, Voskresensky IV, Komalavilas P, Cheung-Flynn J, Guzman RJ, Brophy CM (2012) Ann Vasc Surg 26:1130-44 | 2012 |
| Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice. Tanaka K, Furuyashiki T, Kitaoka S, Senzai Y, Imoto Y, Segi-Nishida E, Deguchi Y, Breyer RM, Breyer MD, Narumiya S (2012) J Neurosci 32:4319-29 | 2012 |
| Inhibition of integrin α2β1 ameliorates glomerular injury. Borza CM, Su Y, Chen X, Yu L, Mont S, Chetyrkin S, Voziyan P, Hudson BG, Billings PC, Jo H, Bennett JS, Degrado WF, Eckes B, Zent R, Pozzi A (2012) J Am Soc Nephrol 23:1027-38 | 2012 |
| Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury. Chen J, Chen JK, Harris RC (2012) Kidney Int 82:45-52 | 2012 |
| The role of cell-extracellular matrix interactions in glomerular injury. Borza CM, Pozzi A (2012) Exp Cell Res 318:1001-10 | 2012 |
| TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Novitskiy SV, Pickup MW, Gorska AE, Owens P, Chytil A, Aakre M, Wu H, Shyr Y, Moses HL (2011) Cancer Discov 1:430-41 | 2011 |
| Dopamine, the kidney, and hypertension. Harris RC, Zhang MZ (2012) Curr Hypertens Rep 14:138-43 | 2012 |
| EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps. Lindert S, Alexander N, Wötzel N, Karakaş M, Stewart PL, Meiler J (2012) Structure 20:464-78 | 2012 |
| Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice. Polosukhin VV, Degryse AL, Newcomb DC, Jones BR, Ware LB, Lee JW, Loyd JE, Blackwell TS, Lawson WE (2012) Exp Lung Res 38:135-46 | 2012 |
| Telomerase deficiency does not alter bleomycin-induced fibrosis in mice. Degryse AL, Xu XC, Newman JL, Mitchell DB, Tanjore H, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Phillips JA, Cogan JD, Blackwell TS, Lawson WE (2012) Exp Lung Res 38:124-34 | 2012 |
| Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions. Shifrin DA, McConnell RE, Nambiar R, Higginbotham JN, Coffey RJ, Tyska MJ (2012) Curr Biol 22:627-31 | 2012 |
| Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice. Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan R, Schuetz JD (2012) J Biol Chem 287:14456-66 | 2012 |
| Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome. Zhang JJ, Malekpour M, Luo W, Ge L, Olaru F, Wang XP, Bah M, Sado Y, Heidet L, Kleinau S, Fogo AB, Borza DB (2012) J Immunol 188:3268-77 | 2012 |
| Myosin-1A targets to microvilli using multiple membrane binding motifs in the tail homology 1 (TH1) domain. Mazerik JN, Tyska MJ (2012) J Biol Chem 287:13104-15 | 2012 |
| Imaging of podocyte foot processes by fluorescence microscopy. Grgic I, Brooks CR, Hofmeister AF, Bijol V, Bonventre JV, Humphreys BD (2012) J Am Soc Nephrol 23:785-91 | 2012 |
| RAF265 inhibits the growth of advanced human melanoma tumors. Su Y, Vilgelm AE, Kelley MC, Hawkins OE, Liu Y, Boyd KL, Kantrow S, Splittgerber RC, Short SP, Sobolik T, Zaja-Milatovic S, Dahlman KB, Amiri KI, Jiang A, Lu P, Shyr Y, Stuart DD, Levy S, Sosman JA, Richmond A (2012) Clin Cancer Res 18:2184-98 | 2012 |
| Potential of fragment recombination for rational design of proteins. Eisenbeis S, Proffitt W, Coles M, Truffault V, Shanmugaratnam S, Meiler J, Höcker B (2012) J Am Chem Soc 134:4019-22 | 2012 |
| Perioperative plasma F(2)-Isoprostane levels correlate with markers of impaired ventilation in infants with single-ventricle physiology undergoing stage 2 surgical palliation on the cardiopulmonary bypass. Albers E, Donahue BS, Milne G, Saville BR, Wang W, Bichell D, McLaughlin B (2012) Pediatr Cardiol 33:562-8 | 2012 |
| Prediction of HIV-1 protease/inhibitor affinity using RosettaLigand. Lemmon G, Kaufmann K, Meiler J (2012) Chem Biol Drug Des 79:888-96 | 2012 |
| Omental grafting: a cell-based therapy for blood vessel repair. Shelton EL, Poole SD, Reese J, Bader DM (2013) J Tissue Eng Regen Med 7:421-33 | 2013 |
| Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin. Chacon-Heszele MF, Ren D, Reynolds AB, Chi F, Chen P (2012) Development 139:968-78 | 2012 |
| Thrombospondin-1 acts as a ligand for CD148 tyrosine phosphatase. Takahashi K, Mernaugh RL, Friedman DB, Weller R, Tsuboi N, Yamashita H, Quaranta V, Takahashi T (2012) Proc Natl Acad Sci U S A 109:1985-90 | 2012 |
| Gel microstructure regulates proliferation and differentiation of MC3T3-E1 cells encapsulated in alginate beads. Lee BH, Li B, Guelcher SA (2012) Acta Biomater 8:1693-702 | 2012 |
| New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2. Praekelt U, Kopp PM, Rehm K, Linder S, Bate N, Patel B, Debrand E, Manso AM, Ross RS, Conti F, Zhang MZ, Harris RC, Zent R, Critchley DR, Monkley SJ (2012) Eur J Cell Biol 91:180-91 | 2012 |
| XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling. Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E (2012) Mol Cell 45:619-28 | 2012 |
| Degradable segmented polyurethane elastomers for bone tissue engineering: effect of polycaprolactone content. Kavlock KD, Whang K, Guelcher SA, Goldstein AS (2013) J Biomater Sci Polym Ed 24:77-93 | 2013 |
| Ab initio protein modeling into CryoEM density maps using EM-Fold. Lindert S, Hofmann T, Wötzel N, Karakaş M, Stewart PL, Meiler J (2012) Biopolymers 97:669-77 | 2012 |
| Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy. Yu L, Su Y, Paueksakon P, Cheng H, Chen X, Wang H, Harris RC, Zent R, Pozzi A (2012) Kidney Int 81:1086-97 | 2012 |
| The dynamic yin-yang interaction of CXCR4 and CXCR7 in breast cancer metastasis. Hawkins OE, Richmond A (2012) Breast Cancer Res 14:103 | 2012 |
| Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis. Tanjore H, Blackwell TS, Lawson WE (2012) Am J Physiol Lung Cell Mol Physiol 302:L721-9 | 2012 |
| Expression and localization of myosin-1d in the developing nervous system. Benesh AE, Fleming JT, Chiang C, Carter BD, Tyska MJ (2012) Brain Res 1440:9-22 | 2012 |
| SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication. Bétous R, Mason AC, Rambo RP, Bansbach CE, Badu-Nkansah A, Sirbu BM, Eichman BF, Cortez D (2012) Genes Dev 26:151-62 | 2012 |
| Discovery of 2-(2-benzoxazoyl amino)-4-aryl-5-cyanopyrimidine as negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGlu₅): from an artificial neural network virtual screen to an in vivo tool compound. Mueller R, Dawson ES, Meiler J, Rodriguez AL, Chauder BA, Bates BS, Felts AS, Lamb JP, Menon UN, Jadhav SB, Kane AS, Jones CK, Gregory KJ, Niswender CM, Conn PJ, Olsen CM, Winder DG, Emmitte KA, Lindsley CW (2012) ChemMedChem 7:406-14 | 2012 |
| A secreted MMP is required for reepithelialization during wound healing. Stevens LJ, Page-McCaw A (2012) Mol Biol Cell 23:1068-79 | 2012 |
| Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E (2012) Bioorg Med Chem 20:1869-77 | 2012 |
| Optical imaging of metabolism in HER2 overexpressing breast cancer cells. Walsh A, Cook RS, Rexer B, Arteaga CL, Skala MC (2012) Biomed Opt Express 3:75-85 | 2012 |
| Total Synthesis (+)-7-Bromotrypargine and Unnatural Analogs: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance. Brogan JT, Stoops SL, Crews BC, Marnett LJ, Lindsley CW (2011) ACS Chem Neurosci 2:633-639 | 2011 |
| EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis. Funk SD, Yurdagul A, Albert P, Traylor JG, Jin L, Chen J, Orr AW (2012) Arterioscler Thromb Vasc Biol 32:686-95 | 2012 |
| Structure-function analysis of endogenous lectin mind-the-gap in synaptogenesis. Rushton E, Rohrbough J, Deutsch K, Broadie K (2012) Dev Neurobiol 72:1161-79 | 2012 |
| Bicelles at low concentrations. Lu Z, Van Horn WD, Chen J, Mathew S, Zent R, Sanders CR (2012) Mol Pharm 9:752-61 | 2012 |
| Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation. Gupta MK, Walthall JM, Venkataraman R, Crowder SW, Jung DK, Yu SS, Feaster TK, Wang X, Giorgio TD, Hong CC, Baudenbacher FJ, Hatzopoulos AK, Sung HJ (2011) PLoS One 6:e28935 | 2011 |
| Angiotensin II induces epithelial-to-mesenchymal transition in renal epithelial cells through reactive oxygen species/Src/caveolin-mediated activation of an epidermal growth factor receptor-extracellular signal-regulated kinase signaling pathway. Chen J, Chen JK, Harris RC (2012) Mol Cell Biol 32:981-91 | 2012 |
| Hold tight or you'll fall off: CD151 helps podocytes stick in high-pressure situations. Pozzi A, Zent R (2012) J Clin Invest 122:13-6 | 2012 |
| Rosetta Ligand docking with flexible XML protocols. Lemmon G, Meiler J (2012) Methods Mol Biol 819:143-55 | 2012 |
| Right place, right time: the evolving role of herpesvirus infection as a "second hit" in idiopathic pulmonary fibrosis. Kropski JA, Lawson WE, Blackwell TS (2012) Am J Physiol Lung Cell Mol Physiol 302:L441-4 | 2012 |
| The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium. Balko JM, Miller TW, Morrison MM, Hutchinson K, Young C, Rinehart C, Sánchez V, Jee D, Polyak K, Prat A, Perou CM, Arteaga CL, Cook RS (2012) Proc Natl Acad Sci U S A 109:221-6 | 2012 |
| Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury. Yang S, Yao B, Zhou Y, Yin H, Zhang MZ, Harris RC (2012) Am J Physiol Renal Physiol 302:F742-9 | 2012 |
| Nucleic acid recognition by tandem helical repeats. Rubinson EH, Eichman BF (2012) Curr Opin Struct Biol 22:101-9 | 2012 |
| Abnormalities in renal dopamine signaling and hypertension: the role of GRK4. Harris RC (2012) Curr Opin Nephrol Hypertens 21:61-5 | 2012 |
| CellAnimation: an open source MATLAB framework for microscopy assays. Georgescu W, Wikswo JP, Quaranta V (2012) Bioinformatics 28:138-9 | 2012 |
| A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis. Alli R, Nguyen P, Boyd K, Sundberg JP, Geiger TL (2012) J Immunol 188:477-86 | 2012 |
| Role of blood pressure and the renin-angiotensin system in development of diabetic nephropathy (DN) in eNOS-/- db/db mice. Zhang MZ, Wang S, Yang S, Yang H, Fan X, Takahashi T, Harris RC (2012) Am J Physiol Renal Physiol 302:F433-8 | 2012 |
| Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells. Singh P, Hoggatt J, Hu P, Speth JM, Fukuda S, Breyer RM, Pelus LM (2012) Blood 119:1671-82 | 2012 |
| Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Liu Y, Belkina NV, Park C, Nambiar R, Loughhead SM, Patino-Lopez G, Ben-Aissa K, Hao JJ, Kruhlak MJ, Qi H, von Andrian UH, Kehrl JH, Tyska MJ, Shaw S (2012) Blood 119:445-53 | 2012 |
| Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds. Adolph EJ, Hafeman AE, Davidson JM, Nanney LB, Guelcher SA (2012) J Biomed Mater Res A 100:450-61 | 2012 |
| EGFR signaling promotes TGFβ-dependent renal fibrosis. Chen J, Chen JK, Nagai K, Plieth D, Tan M, Lee TC, Threadgill DW, Neilson EG, Harris RC (2012) J Am Soc Nephrol 23:215-24 | 2012 |
| Solution NMR approaches for establishing specificity of weak heterodimerization of membrane proteins. Zhuang T, Jap BK, Sanders CR (2011) J Am Chem Soc 133:20571-80 | 2011 |
| In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. Coffee RL, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K (2012) Hum Mol Genet 21:900-15 | 2012 |
| The effects of cholera toxin on cellular energy metabolism. Snider RM, McKenzie JR, Kraft L, Kozlov E, Wikswo JP, Cliffel DE (2010) Toxins (Basel) 2:632-48 | 2010 |
| Isolation & characterization of Hoechst(low) CD45(negative) mouse lung mesenchymal stem cells. Chow KS, Jun D, Helm KM, Wagner DH, Majka SM (2011) J Vis Exp :e3159 | 2011 |
| Sustained local delivery of siRNA from an injectable scaffold. Nelson CE, Gupta MK, Adolph EJ, Shannon JM, Guelcher SA, Duvall CL (2012) Biomaterials 33:1154-61 | 2012 |
| Unraveling a connection between DNA demethylation repair and cancer. Camps M, Eichman BF (2011) Mol Cell 44:343-4 | 2011 |
| A critical role for macrophages in promotion of urethane-induced lung carcinogenesis. Zaynagetdinov R, Sherrill TP, Polosukhin VV, Han W, Ausborn JA, McLoed AG, McMahon FB, Gleaves LA, Degryse AL, Stathopoulos GT, Yull FE, Blackwell TS (2011) J Immunol 187:5703-11 | 2011 |
| Loss of the α2β1 integrin alters human papilloma virus-induced squamous carcinoma progression in vivo and in vitro. Tran T, Barlow B, O'Rear L, Jarvis B, Li Z, Dickeson K, Dupont W, Zutter M (2011) PLoS One 6:e26858 | 2011 |
| Body fluid dynamics: back to the future. Bhave G, Neilson EG (2011) J Am Soc Nephrol 22:2166-81 | 2011 |
| Measurement of aptamer-protein interactions with back-scattering interferometry. Olmsted IR, Xiao Y, Cho M, Csordas AT, Sheehan JH, Meiler J, Soh HT, Bornhop DJ (2011) Anal Chem 83:8867-70 | 2011 |
| Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin. Smith AL, Dohn MR, Brown MV, Reynolds AB (2012) Mol Biol Cell 23:99-110 | 2012 |
| Meta-analysis of clear cell renal cell carcinoma gene expression defines a variant subgroup and identifies gender influences on tumor biology. Brannon AR, Haake SM, Hacker KE, Pruthi RS, Wallen EM, Nielsen ME, Rathmell WK (2012) Eur Urol 61:258-68 | 2012 |
| Expanding the utility of NMR restraints with paramagnetic compounds: background and practical aspects. Koehler J, Meiler J (2011) Prog Nucl Magn Reson Spectrosc 59:360-89 | 2011 |
| Dual delivery of an antibiotic and a growth factor addresses both the microbiological and biological challenges of contaminated bone fractures. Wenke JC, Guelcher SA (2011) Expert Opin Drug Deliv 8:1555-69 | 2011 |
| The plasticity of regulatory T cell function. Pillai MR, Collison LW, Wang X, Finkelstein D, Rehg JE, Boyd K, Szymczak-Workman AL, Doggett T, Griffith TS, Ferguson TA, Vignali DA (2011) J Immunol 187:4987-97 | 2011 |
| Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes. Zaynagetdinov R, Stathopoulos GT, Sherrill TP, Cheng DS, McLoed AG, Ausborn JA, Polosukhin VV, Connelly L, Zhou W, Fingleton B, Peebles RS, Prince LS, Yull FE, Blackwell TS (2012) Oncogene 31:3164-76 | 2012 |
| Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. Volckaert T, Dill E, Campbell A, Tiozzo C, Majka S, Bellusci S, De Langhe SP (2011) J Clin Invest 121:4409-19 | 2011 |
| β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors. Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R (2011) Am J Pathol 179:3045-55 | 2011 |
| Imatinib therapy for non-infection-related type II cryoglobulinemia with membranoproliferative glomerulonephritis. Wallace E, Fogo AB, Schulman G (2012) Am J Kidney Dis 59:122-5 | 2012 |
| Macrophage polarization by angiotensin II-type 1 receptor aggravates renal injury-acceleration of atherosclerosis. Yamamoto S, Yancey PG, Zuo Y, Ma LJ, Kaseda R, Fogo AB, Ichikawa I, Linton MF, Fazio S, Kon V (2011) Arterioscler Thromb Vasc Biol 31:2856-64 | 2011 |
| Exploring symmetry as an avenue to the computational design of large protein domains. Fortenberry C, Bowman EA, Proffitt W, Dorr B, Combs S, Harp J, Mizoue L, Meiler J (2011) J Am Chem Soc 133:18026-9 | 2011 |
| Cells derived from young bone marrow alleviate renal aging. Yang HC, Rossini M, Ma LJ, Zuo Y, Ma J, Fogo AB (2011) J Am Soc Nephrol 22:2028-36 | 2011 |
| NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway. Thu YM, Su Y, Yang J, Splittgerber R, Na S, Boyd A, Mosse C, Simons C, Richmond A (2012) Oncogene 31:2580-92 | 2012 |
| Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population. Wang WD, Melville DB, Montero-Balaguer M, Hatzopoulos AK, Knapik EW (2011) Dev Biol 360:173-85 | 2011 |
| Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system. Lebois EP, Bridges TM, Lewis LM, Dawson ES, Kane AS, Xiang Z, Jadhav SB, Yin H, Kennedy JP, Meiler J, Niswender CM, Jones CK, Conn PJ, Weaver CD, Lindsley CW (2010) ACS Chem Neurosci 1:104-121 | 2010 |
| Analysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylase. Adhikary S, Eichman BF (2011) EMBO Rep 12:1286-92 | 2011 |
| Synthesis, characterization of calcium phosphates/polyurethane composites for weight-bearing implants. Yoshii T, Dumas JE, Okawa A, Spengler DM, Guelcher SA (2012) J Biomed Mater Res B Appl Biomater 100:32-40 | 2012 |
| An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci. Bradley KM, Breyer JP, Melville DB, Broman KW, Knapik EW, Smith JR (2011) G3 (Bethesda) 1:3-9 | 2011 |
| Relativity and the kidney: observations regarding glomerular density. Fogo AB (2011) Nephrol Dial Transplant 26:3425-6 | 2011 |
| A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization. Palmer GM, Tiran Z, Zhou Z, Capozzi ME, Park W, Coletta C, Pyriochou A, Kliger Y, Levy O, Borukhov I, Dewhirst MW, Rotman G, Penn JS, Papapetropoulos A (2012) Br J Pharmacol 165:1891-1903 | 2012 |
| Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82. Alymova IV, Green AM, van de Velde N, McAuley JL, Boyd KL, Ghoneim HE, McCullers JA (2011) J Virol 85:12324-33 | 2011 |
| Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome. Brantley-Sieders DM, Jiang A, Sarma K, Badu-Nkansah A, Walter DL, Shyr Y, Chen J (2011) PLoS One 6:e24426 | 2011 |
| Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis. Legate KR, Takahashi S, Bonakdar N, Fabry B, Boettiger D, Zent R, Fässler R (2011) EMBO J 30:4539-53 | 2011 |
| Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL (2011) J Clin Invest 121:4106-17 | 2011 |
| Design of native-like proteins through an exposure-dependent environment potential. DeLuca S, Dorr B, Meiler J (2011) Biochemistry 50:8521-8 | 2011 |
| Membranous nephropathy with crescents. Basford AW, Lewis J, Dwyer JP, Fogo AB (2011) J Am Soc Nephrol 22:1804-8 | 2011 |
| Renal collecting system growth and function depend upon embryonic γ1 laminin expression. Yang DH, McKee KK, Chen ZL, Mernaugh G, Strickland S, Zent R, Yurchenco PD (2011) Development 138:4535-44 | 2011 |
| Mutations in fam20b and xylt1 reveal that cartilage matrix controls timing of endochondral ossification by inhibiting chondrocyte maturation. Eames BF, Yan YL, Swartz ME, Levic DS, Knapik EW, Postlethwait JH, Kimmel CB (2011) PLoS Genet 7:e1002246 | 2011 |
| Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza. Karlström A, Heston SM, Boyd KL, Tuomanen EI, McCullers JA (2011) J Infect Dis 204:1358-66 | 2011 |
| NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model. Connelly L, Barham W, Onishko HM, Chen L, Sherrill TP, Zabuawala T, Ostrowski MC, Blackwell TS, Yull FE (2011) Breast Cancer Res 13:R83 | 2011 |
| IQGAP1 is a novel CXCR2-interacting protein and essential component of the "chemosynapse". Neel NF, Sai J, Ham AJ, Sobolik-Delmaire T, Mernaugh RL, Richmond A (2011) PLoS One 6:e23813 | 2011 |
| Continuous antagonism by Dkk1 counter activates canonical Wnt signaling and promotes cardiomyocyte differentiation of embryonic stem cells. Rai M, Walthall JM, Hu J, Hatzopoulos AK (2012) Stem Cells Dev 21:54-66 | 2012 |
| A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E (2011) J Biomol Screen 16:995-1006 | 2011 |
| Isoprostane generation and function. Milne GL, Yin H, Hardy KD, Davies SS, Roberts LJ (2011) Chem Rev 111:5973-96 | 2011 |
| The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation. Brooks JD, Musiek ES, Koestner TR, Stankowski JN, Howard JR, Brunoldi EM, Porta A, Zanoni G, Vidari G, Morrow JD, Milne GL, McLaughlin B (2011) J Neurochem 119:604-16 | 2011 |
| Automated refinement and inference of analytical models for metabolic networks. Schmidt MD, Vallabhajosyula RR, Jenkins JW, Hood JE, Soni AS, Wikswo JP, Lipson H (2011) Phys Biol 8:055011 | 2011 |
| Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130). Revert-Ros F, López-Pascual E, Granero-Moltó F, Macías J, Breyer R, Zent R, Hudson BG, Saadeddin A, Revert F, Blasco R, Navarro C, Burks D, Saus J (2011) J Biol Chem 286:35030-43 | 2011 |
| Structural basis for the Trembler-J phenotype of Charcot-Marie-Tooth disease. Sakakura M, Hadziselimovic A, Wang Z, Schey KL, Sanders CR (2011) Structure 19:1160-9 | 2011 |
| Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS. Zagol-Ikapitte IA, Matafonova E, Amarnath V, Bodine CL, Boutaud O, Tirona RG, Oates JA, Roberts LJ, Davies SS (2010) Pharmaceutics 2:18-29 | 2010 |
| Assessing neuronal bioenergetic status. Zeiger SL, Stankowski JN, McLaughlin B (2011) Methods Mol Biol 758:215-35 | 2011 |
| Prostaglandin E2 modulation of blood pressure homeostasis: studies in rodent models. Swan CE, Breyer RM (2011) Prostaglandins Other Lipid Mediat 96:10-3 | 2011 |
| Autotaxin and LPA receptors represent potential molecular targets for the radiosensitization of murine glioma through effects on tumor vasculature. Schleicher SM, Thotala DK, Linkous AG, Hu R, Leahy KM, Yazlovitskaya EM, Hallahan DE (2011) PLoS One 6:e22182 | 2011 |
| Fabrication of a model continuously graded co-electrospun mesh for regeneration of the ligament-bone interface. Samavedi S, Olsen Horton C, Guelcher SA, Goldstein AS, Whittington AR (2011) Acta Biomater 7:4131-8 | 2011 |
| Contribution of bone tissue modulus to breast cancer metastasis to bone. Guelcher SA, Sterling JA (2011) Cancer Microenviron 4:247-59 | 2011 |
| NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS (2011) J Immunol 187:2740-7 | 2011 |
| High-throughput quantification of bioactive lipids by MALDI mass spectrometry: application to prostaglandins. Manna JD, Reyzer ML, Latham JC, Weaver CD, Marnett LJ, Caprioli RM (2011) Anal Chem 83:6683-8 | 2011 |
| Postinfectious glomerulonephritis: Is there a role for steroids? Kapadia AS, Panda M, Fogo AB (2011) Indian J Nephrol 21:116-9 | 2011 |
| A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors. Pyburn TM, Bensing BA, Xiong YQ, Melancon BJ, Tomasiak TM, Ward NJ, Yankovskaya V, Oliver KM, Cecchini G, Sulikowski GA, Tyska MJ, Sullam PM, Iverson TM (2011) PLoS Pathog 7:e1002112 | 2011 |
| PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression. Zhou W, Dowell DR, Geraci MW, Blackwell TS, Collins RD, Polosukhin VV, Lawson WE, Wu P, Sussan T, Biswal S, Goleniewska K, O'Neal J, Newcomb DC, Toki S, Morrow JD, Peebles RS (2011) Am J Physiol Lung Cell Mol Physiol 301:L615-22 | 2011 |
| Pyridoxamine protects protein backbone from oxidative fragmentation. Chetyrkin S, Mathis M, Hayes McDonald W, Shackelford X, Hudson B, Voziyan P (2011) Biochem Biophys Res Commun 411:574-9 | 2011 |
| FSGS lesions in IgA nephropathy. Fogo AB, Alpers CE, D'Agati VD (2011) Kidney Int 80:319; author reply 319-20 | 2011 |
| Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress. Tanjore H, Cheng DS, Degryse AL, Zoz DF, Abdolrasulnia R, Lawson WE, Blackwell TS (2011) J Biol Chem 286:30972-80 | 2011 |
| Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. Van De Water TR, Abi Hachem RN, Dinh CT, Bas E, Haake SM, Hoosien G, Vivero R, Chan S, He J, Eshraghi AA, Angeli SI, Telischi FF, Balkany TJ (2010) Cochlear Implants Int 11 Suppl 1:42-55 | 2010 |
| Cardiovascular disease: several small shocks beat one big one. Gray RA, Wikswo JP (2011) Nature 475:181-2 | 2011 |
| The evolutionary history of the catenin gene family during metazoan evolution. Zhao ZM, Reynolds AB, Gaucher EA (2011) BMC Evol Biol 11:198 | 2011 |
| Application of small organic molecules reveals cooperative TGFβ and BMP regulation of mesothelial cell behaviors. Cross EE, Thomason RT, Martinez M, Hopkins CR, Hong CC, Bader DM (2011) ACS Chem Biol 6:952-61 | 2011 |
| Dual-purpose bone grafts improve healing and reduce infection. Guelcher SA, Brown KV, Li B, Guda T, Lee BH, Wenke JC (2011) J Orthop Trauma 25:477-82 | 2011 |
| Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression. Cheng H, Fan X, Moeckel GW, Harris RC (2011) J Am Soc Nephrol 22:1240-51 | 2011 |
| Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo. Bilousova G, Jun du H, King KB, De Langhe S, Chick WS, Torchia EC, Chow KS, Klemm DJ, Roop DR, Majka SM (2011) Stem Cells 29:206-16 | 2011 |
| RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite. Fleishman SJ, Leaver-Fay A, Corn JE, Strauch EM, Khare SD, Koga N, Ashworth J, Murphy P, Richter F, Lemmon G, Meiler J, Baker D (2011) PLoS One 6:e20161 | 2011 |
| Evaluation of nanoparticle uptake in tumors in real time using intravital imaging. Cho CF, Ablack A, Leong HS, Zijlstra A, Lewis J (2011) J Vis Exp : | 2011 |
| Role of vascular extracellular superoxide dismutase in hypertension. Lob HE, Vinh A, Li L, Blinder Y, Offermanns S, Harrison DG (2011) Hypertension 58:232-9 | 2011 |
| A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport. Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD (2011) J Biol Chem 286:30823-36 | 2011 |
| The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis. Melville DB, Montero-Balaguer M, Levic DS, Bradley K, Smith JR, Hatzopoulos AK, Knapik EW (2011) Dis Model Mech 4:763-76 | 2011 |
| Podocyte injury damages other podocytes. Matsusaka T, Sandgren E, Shintani A, Kon V, Pastan I, Fogo AB, Ichikawa I (2011) J Am Soc Nephrol 22:1275-85 | 2011 |
| Microfabricated scaffold-guided endothelial morphogenesis in three-dimensional culture. Liu Y, Markov DA, Wikswo JP, McCawley LJ (2011) Biomed Microdevices 13:837-46 | 2011 |
| Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1α, suppress amyloid β-induced neurotoxicity. Raman D, Milatovic SZ, Milatovic D, Splittgerber R, Fan GH, Richmond A (2011) Toxicol Appl Pharmacol 256:300-13 | 2011 |
| Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. Zhang MZ, Yao B, Wang S, Fan X, Wu G, Yang H, Yin H, Yang S, Harris RC (2011) J Clin Invest 121:2845-54 | 2011 |
| Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs. Lawson WE, Cheng DS, Degryse AL, Tanjore H, Polosukhin VV, Xu XC, Newcomb DC, Jones BR, Roldan J, Lane KB, Morrisey EE, Beers MF, Yull FE, Blackwell TS (2011) Proc Natl Acad Sci U S A 108:10562-7 | 2011 |
| Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues. Chetyrkin S, Mathis M, Pedchenko V, Sanchez OA, McDonald WH, Hachey DL, Madu H, Stec D, Hudson B, Voziyan P (2011) Biochemistry 50:6102-12 | 2011 |
| Pathology of human diabetic nephropathy. Najafian B, Alpers CE, Fogo AB (2011) Contrib Nephrol 170:36-47 | 2011 |
| Epithelial organization: new perspective on α-catenin from an ancient source. Reynolds AB (2011) Curr Biol 21:R430-2 | 2011 |
| Milk and membranous nephropathy. Fogo AB (2011) N Engl J Med 364:2158-9 | 2011 |
| Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction. Zoz DF, Lawson WE, Blackwell TS (2011) Am J Med Sci 341:435-8 | 2011 |
| Adenoma formation following limited ablation of p120-catenin in the mouse intestine. Smalley-Freed WG, Efimov A, Short SP, Jia P, Zhao Z, Washington MK, Robine S, Coffey RJ, Reynolds AB (2011) PLoS One 6:e19880 | 2011 |
| The targeted podocyte. Fogo AB (2011) J Clin Invest 121:2142-5 | 2011 |
| Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit. Van Eps N, Preininger AM, Alexander N, Kaya AI, Meier S, Meiler J, Hamm HE, Hubbell WL (2011) Proc Natl Acad Sci U S A 108:9420-4 | 2011 |
| Vitamin E prevents NRF2 suppression by allergens in asthmatic alveolar macrophages in vivo. Dworski R, Han W, Blackwell TS, Hoskins A, Freeman ML (2011) Free Radic Biol Med 51:516-21 | 2011 |
| Integrins in renal development. Mathew S, Chen X, Pozzi A, Zent R (2012) Pediatr Nephrol 27:891-900 | 2012 |
| How do control-based approaches enter into biology? LeDuc PR, Messner WC, Wikswo JP (2011) Annu Rev Biomed Eng 13:369-96 | 2011 |
| Measuring differences in compositional properties of bone tissue by confocal Raman spectroscopy. Nyman JS, Makowski AJ, Patil CA, Masui TP, O'Quinn EC, Bi X, Guelcher SA, Nicollela DP, Mahadevan-Jansen A (2011) Calcif Tissue Int 89:111-22 | 2011 |
| Protective effects of PPARγ agonist in acute nephrotic syndrome. Zuo Y, Yang HC, Potthoff SA, Najafian B, Kon V, Ma LJ, Fogo AB (2012) Nephrol Dial Transplant 27:174-81 | 2012 |
| BCL::EM-Fit: rigid body fitting of atomic structures into density maps using geometric hashing and real space refinement. Woetzel N, Lindert S, Stewart PL, Meiler J (2011) J Struct Biol 175:264-76 | 2011 |
| Extracellular matrix receptors in branched organs. Pozzi A, Zent R (2011) Curr Opin Cell Biol 23:547-53 | 2011 |
| External control of the GAL network in S. cerevisiae: a view from control theory. Yang R, Lenaghan SC, Wikswo JP, Zhang M (2011) PLoS One 6:e19353 | 2011 |
| Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. Polosukhin VV, Cates JM, Lawson WE, Milstone AP, Matafonov AG, Massion PP, Lee JW, Randell SH, Blackwell TS (2011) J Pathol 224:203-11 | 2011 |
| Validation of the Oxford classification of IgA nephropathy. Herzenberg AM, Fogo AB, Reich HN, Troyanov S, Bavbek N, Massat AE, Hunley TE, Hladunewich MA, Julian BA, Fervenza FC, Cattran DC (2011) Kidney Int 80:310-7 | 2011 |
| Regional increase of extracellular potassium leads to electrical instability and reentry occurrence through the spatial heterogeneity of APD restitution. Sidorov VY, Uzelac I, Wikswo JP (2011) Am J Physiol Heart Circ Physiol 301:H209-20 | 2011 |
| Amphiregulin exosomes increase cancer cell invasion. Higginbotham JN, Demory Beckler M, Gephart JD, Franklin JL, Bogatcheva G, Kremers GJ, Piston DW, Ayers GD, McConnell RE, Tyska MJ, Coffey RJ (2011) Curr Biol 21:779-86 | 2011 |
| Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS (2011) Am J Respir Crit Care Med 184:317-27 | 2011 |
| Selective, α2β1 integrin-dependent secretion of il-6 by connective tissue mast cells. McCall-Culbreath KD, Li Z, Zhang Z, Lu LX, Orear L, Zutter MM (2011) J Innate Immun 3:459-70 | 2011 |
| Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Stairs DB, Bayne LJ, Rhoades B, Vega ME, Waldron TJ, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Reynolds AB, Vonderheide RH, Rustgi AK (2011) Cancer Cell 19:470-83 | 2011 |
| Membrane protein structure determination using paramagnetic tags. Ganguly S, Weiner BE, Meiler J (2011) Structure 19:441-3 | 2011 |
| Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice. Madhur MS, Funt SA, Li L, Vinh A, Chen W, Lob HE, Iwakura Y, Blinder Y, Rahman A, Quyyumi AA, Harrison DG (2011) Arterioscler Thromb Vasc Biol 31:1565-72 | 2011 |
| Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside. Ma J, Matsusaka T, Yang HC, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I (2011) Pediatr Res 70:83-9 | 2011 |
| Sulphilimine cross-links in Goodpasture's disease. Vanacore R, Pedchenko V, Bhave G, Hudson BG (2011) Clin Exp Immunol 164 Suppl 1:4-6 | 2011 |
| TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment. Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE (2011) Am J Physiol Lung Cell Mol Physiol 300:L887-97 | 2011 |
| Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles. Donowitz M, Singh S, Singh P, Chakraborty M, Chen Y, Murtazina R, Gucek M, Cole RN, Zachos NC, Salahuddin FF, Kovbasnjuk O, Broere N, Smalley-Freed WG, Reynolds AB, Hubbard AL, Seidler U, Weinman E, de Jonge HR, Hogema BM, Li X (2011) Physiol Genomics 43:674-84 | 2011 |
| Bone structural components regulating sites of tumor metastasis. Sterling JA, Guelcher SA (2011) Curr Osteoporos Rep 9:89-95 | 2011 |
| Influence of cell cycle phase on apparent diffusion coefficient in synchronized cells detected using temporal diffusion spectroscopy. Xu J, Xie J, Jourquin J, Colvin DC, Does MD, Quaranta V, Gore JC (2011) Magn Reson Med 65:920-6 | 2011 |
| Increased capillary branching contributes to angiotensin type 1 receptor blocker (ARB)-induced regression of sclerosis. Scruggs BS, Zuo Y, Donnert E, Ma L, Bertram JF, Fogo AB (2011) Am J Pathol 178:1891-8 | 2011 |
| Localization of culprit lesions in coronary arteries of patients with ST-segment elevation myocardial infarctions: relation to bifurcations and curvatures. McDaniel MC, Galbraith EM, Jeroudi AM, Kashlan OR, Eshtehardi P, Suo J, Dhawan S, Voeltz M, Devireddy C, Oshinski J, Harrison DG, Giddens DP, Samady H (2011) Am Heart J 161:508-15 | 2011 |
| Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation. Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB (2011) Oncogene 30:3234-47 | 2011 |
| Goodpasture's disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesis. Pedchenko V, Vanacore R, Hudson B (2011) Curr Opin Nephrol Hypertens 20:290-6 | 2011 |
| Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity. Ma LJ, Corsa BA, Zhou J, Yang H, Li H, Tang YW, Babaev VR, Major AS, Linton MF, Fazio S, Hunley TE, Kon V, Fogo AB (2011) Am J Physiol Renal Physiol 300:F1203-13 | 2011 |
| Computational design of an endo-1,4-beta-xylanase ligand binding site. Morin A, Kaufmann KW, Fortenberry C, Harp JM, Mizoue LS, Meiler J (2011) Protein Eng Des Sel 24:503-16 | 2011 |
| Membrane-type 4 matrix metalloproteinase (MT4-MMP) modulates water homeostasis in mice. Srichai MB, Colleta H, Gewin L, Matrisian L, Abel TW, Koshikawa N, Seiki M, Pozzi A, Harris RC, Zent R (2011) PLoS One 6:e17099 | 2011 |
| Role of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation. Chen W, Li L, Brod T, Saeed O, Thabet S, Jansen T, Dikalov S, Weyand C, Goronzy J, Harrison DG (2011) J Biol Chem 286:13846-51 | 2011 |
| Improving bone formation in a rat femur segmental defect by controlling bone morphogenetic protein-2 release. Brown KV, Li B, Guda T, Perrien DS, Guelcher SA, Wenke JC (2011) Tissue Eng Part A 17:1735-46 | 2011 |
| Single-nanocrystal spectroscopy of white-light-emitting CdSe nanocrystals. Dukes AD, Samson PC, Keene JD, Davis LM, Wikswo JP, Rosenthal SJ (2011) J Phys Chem A 115:4076-81 | 2011 |
| Proteomic analysis of the enterocyte brush border. McConnell RE, Benesh AE, Mao S, Tabb DL, Tyska MJ (2011) Am J Physiol Gastrointest Liver Physiol 300:G914-26 | 2011 |
| Computational design of protein-ligand interfaces: potential in therapeutic development. Morin A, Meiler J, Mizoue LS (2011) Trends Biotechnol 29:159-66 | 2011 |
| Models of chronic kidney disease. Yang HC, Zuo Y, Fogo AB (2010) Drug Discov Today Dis Models 7:13-19 | 2010 |
| Bves modulates tight junction associated signaling. Russ PK, Pino CJ, Williams CS, Bader DM, Haselton FR, Chang MS (2011) PLoS One 6:e14563 | 2011 |
| ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes. Smith AL, Friedman DB, Yu H, Carnahan RH, Reynolds AB (2011) PLoS One 6:e16206 | 2011 |
| TGF-β sequestration by mesangial cell integrin αvβ8: A novel mechanism of glomerular endothelial cell regulation. Pozzi A, Zent R (2011) Am J Pathol 178:485-9 | 2011 |
| Sensing and modulation of invadopodia across a wide range of rigidities. Parekh A, Ruppender NS, Branch KM, Sewell-Loftin MK, Lin J, Boyer PD, Candiello JE, Merryman WD, Guelcher SA, Weaver AM (2011) Biophys J 100:573-82 | 2011 |
| Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes. Parkin JD, San Antonio JD, Pedchenko V, Hudson B, Jensen ST, Savige J (2011) Hum Mutat 32:127-43 | 2011 |
| Innate immune function of the adherens junction protein p120-catenin in endothelial response to endotoxin. Wang YL, Malik AB, Sun Y, Hu S, Reynolds AB, Minshall RD, Hu G (2011) J Immunol 186:3180-3187 | 2011 |
| Primary sebaceous carcinoma of the tongue. Oshiro H, Iwai T, Hirota M, Mitsudo K, Tohnai I, Minamimoto R, Omura-Minamisawa M, Nagashima Y, Yamanaka S, Fukui T, Kanazawa M, Sagawa H, Mita K, Nakayama T, Inayama Y (2010) Med Mol Morphol 43:246-52 | 2010 |
| Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice. Yamamoto S, Zuo Y, Ma J, Yancey PG, Hunley TE, Motojima M, Fogo AB, Linton MF, Fazio S, Ichikawa I, Kon V (2011) Nephrol Dial Transplant 26:2491-7 | 2011 |
| Chemokine research moves on. Richmond A (2011) Exp Cell Res 317:553-5 | 2011 |
| Commitment and differentiation of cardiac myocytes. Litvin J, Montgomery M, Gonzalez-Sanchez A, Bisaha JG, Bader D (1992) Trends Cardiovasc Med 2:27-32 | 1992 |
| Chemokines in health and disease. Raman D, Sobolik-Delmaire T, Richmond A (2011) Exp Cell Res 317:575-89 | 2011 |
| The molecular evolution of the p120-catenin subfamily and its functional associations. Carnahan RH, Rokas A, Gaucher EA, Reynolds AB (2010) PLoS One 5:e15747 | 2010 |
| The central nervous system and inflammation in hypertension. Marvar PJ, Lob H, Vinh A, Zarreen F, Harrison DG (2011) Curr Opin Pharmacol 11:156-61 | 2011 |
| Let It Be: microRNAs impact interstitial lung disease. Lawson WE, Blackwell TS, Gauldie J (2011) Am J Respir Crit Care Med 183:1-2 | 2011 |
| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules. Leaver-Fay A, Tyka M, Lewis SM, Lange OF, Thompson J, Jacak R, Kaufman K, Renfrew PD, Smith CA, Sheffler W, Davis IW, Cooper S, Treuille A, Mandell DJ, Richter F, Ban YE, Fleishman SJ, Corn JE, Kim DE, Lyskov S, Berrondo M, Mentzer S, Popović Z, Havranek JJ, Karanicolas J, Das R, Meiler J, Kortemme T, Gray JJ, Kuhlman B, Baker D, Bradley P (2011) Methods Enzymol 487:545-74 | 2011 |
| Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection. Matsusaka T, Kobayashi K, Kon V, Pastan I, Fogo AB, Ichikawa I (2011) Am J Physiol Renal Physiol 300:F792-800 | 2011 |
| Inflammation, immunity, and hypertension. Harrison DG, Guzik TJ, Lob HE, Madhur MS, Marvar PJ, Thabet SR, Vinh A, Weyand CM (2011) Hypertension 57:132-40 | 2011 |
| Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium. Brantley-Sieders DM, Dunaway CM, Rao M, Short S, Hwang Y, Gao Y, Li D, Jiang A, Shyr Y, Wu JY, Chen J (2011) Cancer Res 71:976-87 | 2011 |
| The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer. Ramirez NE, Zhang Z, Madamanchi A, Boyd KL, O'Rear LD, Nashabi A, Li Z, Dupont WD, Zijlstra A, Zutter MM (2011) J Clin Invest 121:226-37 | 2011 |
| Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis. Dunaway CM, Hwang Y, Lindsley CW, Cook RS, Wu JY, Boothby M, Chen J, Brantley-Sieders DM (2011) Mol Cell Biol 31:404-16 | 2011 |
| Navigating the challenges of fibrosis assessment: land in sight? Fogo AB, Alpers CE (2011) J Am Soc Nephrol 22:11-3 | 2011 |
| Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension. Vinh A, Chen W, Blinder Y, Weiss D, Taylor WR, Goronzy JJ, Weyand CM, Harrison DG, Guzik TJ (2010) Circulation 122:2529-37 | 2010 |
| Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity. Wright S, Parham C, Lee B, Clarke D, Auckland L, Johnston J, Lawrence AL, Dickeson SK, Santoro SA, Griswold-Prenner I, Bix G (2012) Neurobiol Aging 33:1379-88 | 2012 |
| Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Rhodes LV, Short SP, Neel NF, Salvo VA, Zhu Y, Elliott S, Wei Y, Yu D, Sun M, Muir SE, Fonseca JP, Bratton MR, Segar C, Tilghman SL, Sobolik-Delmaire T, Horton LW, Zaja-Milatovic S, Collins-Burow BM, Wadsworth S, Beckman BS, Wood CE, Fuqua SA, Nephew KP, Dent P, Worthylake RA, Curiel TJ, Hung MC, Richmond A, Burow ME (2011) Cancer Res 71:603-13 | 2011 |
| Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma. Rejniak KA, Quaranta V, Anderson AR (2012) Math Med Biol 29:67-84 | 2012 |
| Local renal autoantibody production in lupus nephritis. Espeli M, Bökers S, Giannico G, Dickinson HA, Bardsley V, Fogo AB, Smith KG (2011) J Am Soc Nephrol 22:296-305 | 2011 |
| Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells. Ruppender NS, Merkel AR, Martin TJ, Mundy GR, Sterling JA, Guelcher SA (2010) PLoS One 5:e15451 | 2010 |
| Hydrogel-electrospun mesh composites for coronary artery bypass grafts. McMahon RE, Qu X, Jimenez-Vergara AC, Bashur CA, Guelcher SA, Goldstein AS, Hahn MS (2011) Tissue Eng Part C Methods 17:451-61 | 2011 |
| Regulation of endothelial cell tetrahydrobiopterin pathophysiological and therapeutic implications. Harrison DG, Chen W, Dikalov S, Li L (2010) Adv Pharmacol 60:107-32 | 2010 |
| Measurements of transmembrane potential and magnetic field at the apex of the heart. McBride KK, Roth BJ, Sidorov VY, Wikswo JP, Baudenbacher FJ (2010) Biophys J 99:3113-8 | 2010 |
| Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden. Connelly L, Barham W, Onishko HM, Sherrill T, Chodosh LA, Blackwell TS, Yull FE (2011) Oncogene 30:1402-12 | 2011 |
| Algorithm for selection of optimized EPR distance restraints for de novo protein structure determination. Kazmier K, Alexander NS, Meiler J, McHaourab HS (2011) J Struct Biol 173:549-57 | 2011 |
| Towards monitoring real-time cellular response using an integrated microfluidics-matrix assisted laser desorption ionisation/nanoelectrospray ionisation-ion mobility-mass spectrometry platform. Enders JR, Marasco CC, Kole A, Nguyen B, Sevugarajan S, Seale KT, Wikswo JP, McLean JA (2010) IET Syst Biol 4:416-27 | 2010 |
| Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity. Cho K, Vaught TG, Ji H, Gu D, Papasakelariou-Yared C, Horstmann N, Jennings JM, Lee M, Sevilla LM, Kloc M, Reynolds AB, Watt FM, Brennan RG, Kowalczyk AP, McCrea PD (2010) J Cell Sci 123:4128-44 | 2010 |
| RosettaEPR: an integrated tool for protein structure determination from sparse EPR data. Hirst SJ, Alexander N, McHaourab HS, Meiler J (2011) J Struct Biol 173:506-14 | 2011 |
| Domain structure of the DEMETER 5-methylcytosine DNA glycosylase. Mok YG, Uzawa R, Lee J, Weiner GM, Eichman BF, Fischer RL, Huh JH (2010) Proc Natl Acad Sci U S A 107:19225-30 | 2010 |
| Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. Li D, Zhou J, Wang L, Shin ME, Su P, Lei X, Kuang H, Guo W, Yang H, Cheng L, Tanaka TS, Leckband DE, Reynolds AB, Duan E, Wang F (2010) J Cell Biol 191:631-44 | 2010 |
| p120 regulates endothelial permeability independently of its NH2 terminus and Rho binding. Herron CR, Lowery AM, Hollister PR, Reynolds AB, Vincent PA (2011) Am J Physiol Heart Circ Physiol 300:H36-48 | 2011 |
| Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1. Frieden LA, Townsend TA, Vaught DB, Delaughter DM, Hwang Y, Barnett JV, Chen J (2010) Dev Dyn 239:3226-34 | 2010 |
| A metering rotary nanopump for microfluidic systems. Darby SG, Moore MR, Friedlander TA, Schaffer DK, Reiserer RS, Wikswo JP, Seale KT (2010) Lab Chip 10:3218-26 | 2010 |
| Open access microfluidic device for the study of cell migration during chemotaxis. Jowhar D, Wright G, Samson PC, Wikswo JP, Janetopoulos C (2010) Integr Biol (Camb) 2:648-58 | 2010 |
| Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. Borza CM, Chen X, Mathew S, Mont S, Sanders CR, Zent R, Pozzi A (2010) J Biol Chem 285:40114-24 | 2010 |
| A p120-catenin-CK1epsilon complex regulates Wnt signaling. Casagolda D, Del Valle-Pérez B, Valls G, Lugilde E, Vinyoles M, Casado-Vela J, Solanas G, Batlle E, Reynolds AB, Casal JI, de Herreros AG, Duñach M (2010) J Cell Sci 123:2621-31 | 2010 |
| Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking. Kalkhof S, Haehn S, Paulsson M, Smyth N, Meiler J, Sinz A (2010) Proteins 78:3409-27 | 2010 |
| Peptidylarginine deiminase 2 suppresses inhibitory {kappa}B kinase activity in lipopolysaccharide-stimulated RAW 264.7 macrophages. Lee HJ, Joo M, Abdolrasulnia R, Young DG, Choi I, Ware LB, Blackwell TS, Christman BW (2010) J Biol Chem 285:39655-62 | 2010 |
| An unprecedented nucleic acid capture mechanism for excision of DNA damage. Rubinson EH, Gowda AS, Spratt TE, Gold B, Eichman BF (2010) Nature 468:406-11 | 2010 |
| Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Bhave G, Chauder BA, Liu W, Dawson ES, Kadakia R, Nguyen TT, Lewis LM, Meiler J, Weaver CD, Satlin LM, Lindsley CW, Denton JS (2011) Mol Pharmacol 79:42-50 | 2011 |
| Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity. Rodriguez AL, Grier MD, Jones CK, Herman EJ, Kane AS, Smith RL, Williams R, Zhou Y, Marlo JE, Days EL, Blatt TN, Jadhav S, Menon UN, Vinson PN, Rook JM, Stauffer SR, Niswender CM, Lindsley CW, Weaver CD, Conn PJ (2010) Mol Pharmacol 78:1105-23 | 2010 |
| Reduced choroidal neovascular membrane formation in cyclooxygenase-2 null mice. Rezaei KA, Toma HS, Cai J, Penn JS, Sternberg P, Kim SJ (2011) Invest Ophthalmol Vis Sci 52:701-7 | 2011 |
| Linking changes in epithelial morphogenesis to cancer mutations using computational modeling. Rejniak KA, Wang SE, Bryce NS, Chang H, Parvin B, Jourquin J, Estrada L, Gray JW, Arteaga CL, Weaver AM, Quaranta V, Anderson AR (2010) PLoS Comput Biol 6: | 2010 |
| Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds. Hafeman AE, Zienkiewicz KJ, Zachman AL, Sung HJ, Nanney LB, Davidson JM, Guelcher SA (2011) Biomaterials 32:419-29 | 2011 |
| Targeted p120-catenin ablation disrupts dental enamel development. Bartlett JD, Dobeck JM, Tye CE, Perez-Moreno M, Stokes N, Reynolds AB, Fuchs E, Skobe Z (2010) PLoS One 5: | 2010 |
| Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal. Yamashita H, Tripathi M, Jourquin J, Kam Y, Liu S, Weidow B, Quaranta V (2010) J Oncol 2010: | 2010 |
| NF-kappaB activation limits airway branching through inhibition of Sp1-mediated fibroblast growth factor-10 expression. Benjamin JT, Carver BJ, Plosa EJ, Yamamoto Y, Miller JD, Liu JH, van der Meer R, Blackwell TS, Prince LS (2010) J Immunol 185:4896-903 | 2010 |
| Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products. Pozzi A, Zent R (2009) Wiley Interdiscip Rev Syst Biol Med 1:254-272 | 2009 |
| Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development. Smeeton J, Zhang X, Bulus N, Mernaugh G, Lange A, Karner CM, Carroll TJ, Fässler R, Pozzi A, Rosenblum ND, Zent R (2010) Development 137:3233-43 | 2010 |
| Development of high-throughput quantitative assays for glucose uptake in cancer cell lines. Hassanein M, Weidow B, Koehler E, Bakane N, Garbett S, Shyr Y, Quaranta V (2011) Mol Imaging Biol 13:840-52 | 2011 |
| DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway. Ocak S, Yamashita H, Udyavar AR, Miller AN, Gonzalez AL, Zou Y, Jiang A, Yi Y, Shyr Y, Estrada L, Quaranta V, Massion PP (2010) Oncogene 29:6331-42 | 2010 |
| Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice. Doris K, Karabela SP, Kairi CA, Simoes DC, Roussos C, Zakynthinos SG, Kalomenidis I, Blackwell TS, Stathopoulos GT (2010) Respir Res 11:118 | 2010 |
| Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles. Donowitz M, Singh S, Singh P, Salahuddin FF, Chen Y, Chakraborty M, Murtazina R, Gucek M, Cole RN, Zachos NC, Kovbasnjuk O, Broere N, Smalley-Freed WG, Reynolds AB, Hubbard AL, Seidler U, Weinman E, de Jonge HR, Hogema BM, Li X (2010) Physiol Genomics 42A:200-10 | 2010 |
| 3D-QSAR CoMFA study of benzoxazepine derivatives as mGluR5 positive allosteric modulators. Lowe EW, Ferrebee A, Rodriguez AL, Conn PJ, Meiler J (2010) Bioorg Med Chem Lett 20:5922-4 | 2010 |
| CKD in Aboriginal Australians. Hoy WE, Kincaid-Smith P, Hughson MD, Fogo AB, Sinniah R, Dowling J, Samuel T, Mott SA, Douglas-Denton RN, Bertram JF (2010) Am J Kidney Dis 56:983-93 | 2010 |
| MT1-MMP-mediated basement membrane remodeling modulates renal development. Riggins KS, Mernaugh G, Su Y, Quaranta V, Koshikawa N, Seiki M, Pozzi A, Zent R (2010) Exp Cell Res 316:2993-3005 | 2010 |
| Pseudomonas aeruginosa: host defence in lung diseases. Williams BJ, Dehnbostel J, Blackwell TS (2010) Respirology 15:1037-56 | 2010 |
| Cell senescence in the aging kidney. Yang H, Fogo AB (2010) J Am Soc Nephrol 21:1436-9 | 2010 |
| NF-κB inducing kinase: a key regulator in the immune system and in cancer. Thu YM, Richmond A (2010) Cytokine Growth Factor Rev 21:213-26 | 2010 |
| PPARγ and chronic kidney disease. Fogo AB (2011) Pediatr Nephrol 26:347-51 | 2011 |
| Laminin-332 cleavage by matriptase alters motility parameters of prostate cancer cells. Tripathi M, Potdar AA, Yamashita H, Weidow B, Cummings PT, Kirchhofer D, Quaranta V (2011) Prostate 71:184-96 | 2011 |
| Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment. Das ST, Rajagopalan L, Guerrero-Plata A, Sai J, Richmond A, Garofalo RP, Rajarathnam K (2010) PLoS One 5:e11754 | 2010 |
| TRAIL and interferon-alpha act synergistically to induce renal cell carcinoma apoptosis. Clark PE, Polosukhina DA, Gyabaah K, Moses HL, Thorburn A, Zent R (2010) J Urol 184:1166-74 | 2010 |
| Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis. Pedchenko V, Bondar O, Fogo AB, Vanacore R, Voziyan P, Kitching AR, Wieslander J, Kashtan C, Borza DB, Neilson EG, Wilson CB, Hudson BG (2010) N Engl J Med 363:343-54 | 2010 |
| Ketorolac inhibits choroidal neovascularization by suppression of retinal VEGF. Kim SJ, Toma HS, Barnett JM, Penn JS (2010) Exp Eye Res 91:537-43 | 2010 |
| Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs. Aldrich LN, Stoops SL, Crews BC, Marnett LJ, Lindsley CW (2010) Bioorg Med Chem Lett 20:5207-11 | 2010 |
| Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Vaithiyalingam S, Warren EM, Eichman BF, Chazin WJ (2010) Proc Natl Acad Sci U S A 107:13684-9 | 2010 |
| Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motility. Gruver JS, Potdar AA, Jeon J, Sai J, Anderson B, Webb D, Richmond A, Quaranta V, Cummings PT, Chung CY (2010) Biophys J 99:367-76 | 2010 |
| Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. Dikalova AE, Góngora MC, Harrison DG, Lambeth JD, Dikalov S, Griendling KK (2010) Am J Physiol Heart Circ Physiol 299:H673-9 | 2010 |
| Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential. Gregory KJ, Dong EN, Meiler J, Conn PJ (2011) Neuropharmacology 60:66-81 | 2011 |
| A model of disturbed flow-induced atherosclerosis in mouse carotid artery by partial ligation and a simple method of RNA isolation from carotid endothelium. Nam D, Ni CW, Rezvan A, Suo J, Budzyn K, Llanos A, Harrison DG, Giddens DP, Jo H (2010) J Vis Exp : | 2010 |
| 3-Cyano-5-fluoro-N-arylbenzamides as negative allosteric modulators of mGlu(5): Identification of easily prepared tool compounds with CNS exposure in rats. Felts AS, Lindsley SR, Lamb JP, Rodriguez AL, Menon UN, Jadhav S, Jones CK, Conn PJ, Lindsley CW, Emmitte KA (2010) Bioorg Med Chem Lett 20:4390-4 | 2010 |
| Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion. Stathopoulos GT, Sherrill TP, Karabela SP, Goleniewska K, Kalomenidis I, Roussos C, Fingleton B, Yull FE, Peebles RS, Blackwell TS (2010) Am J Respir Crit Care Med 182:1273-81 | 2010 |
| Unique gating properties of C. elegans ClC anion channel splice variants are determined by altered CBS domain conformation and the R-helix linker. Dave S, Sheehan JH, Meiler J, Strange K (2010) Channels (Austin) 4:289-301 | 2010 |
| TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. Gewin L, Bulus N, Mernaugh G, Moeckel G, Harris RC, Moses HL, Pozzi A, Zent R (2010) J Am Soc Nephrol 21:1334-43 | 2010 |
| p120-catenin is a binding partner and substrate for Group B Pak kinases. Wong LE, Reynolds AB, Dissanayaka NT, Minden A (2010) J Cell Biochem 110:1244-54 | 2010 |
| Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis. Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE (2010) Am J Physiol Lung Cell Mol Physiol 299:L442-52 | 2010 |
| Role of NADPH oxidase in host defense against aspergillosis. Grimm MJ, Vethanayagam RR, Almyroudis NG, Lewandowski D, Rall N, Blackwell TS, Segal BH (2011) Med Mycol 49 Suppl 1:S144-9 | 2011 |
| Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Marvar PJ, Thabet SR, Guzik TJ, Lob HE, McCann LA, Weyand C, Gordon FJ, Harrison DG (2010) Circ Res 107:263-70 | 2010 |
| Improved assessment of laser-induced choroidal neovascularization. Toma HS, Barnett JM, Penn JS, Kim SJ (2010) Microvasc Res 80:295-302 | 2010 |
| Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. Siuta MA, Robertson SD, Kocalis H, Saunders C, Gresch PJ, Khatri V, Shiota C, Kennedy JP, Lindsley CW, Daws LC, Polley DB, Veenstra-Vanderweele J, Stanwood GD, Magnuson MA, Niswender KD, Galli A (2010) PLoS Biol 8:e1000393 | 2010 |
| The glomerulus--a view from the outside--the podocyte. Cheng H, Harris RC (2010) Int J Biochem Cell Biol 42:1380-7 | 2010 |
| The glomerulus--a view from the inside--the endothelial cell. Fogo AB, Kon V (2010) Int J Biochem Cell Biol 42:1388-97 | 2010 |
| Myosin-1a: A motor for microvillar membrane movement and mechanics. Tyska MJ, Nambiar R (2010) Commun Integr Biol 3:64-6 | 2010 |
| Conditional ablation of Ikkb inhibits melanoma tumor development in mice. Yang J, Splittgerber R, Yull FE, Kantrow S, Ayers GD, Karin M, Richmond A (2010) J Clin Invest 120:2563-74 | 2010 |
| Design and directed evolution of a dideoxy purine nucleoside phosphorylase. Nannemann DP, Kaufmann KW, Meiler J, Bachmann BO (2010) Protein Eng Des Sel 23:607-16 | 2010 |
| Macro to nano: a simple method for transporting cultured cells from milliliter scale to nanoliter scale. Seale KT, Faley SL, Chamberlain J, Wikswo JP (2010) Exp Biol Med (Maywood) 235:777-83 | 2010 |
| Cellular retinol binding protein 1 modulates photoreceptor outer segment folding in the isolated eye. Wang X, Tong Y, Giorgianni F, Beranova-Giorgianni S, Penn JS, Jablonski MM (2010) Dev Neurobiol 70:623-35 | 2010 |
| Protective role of extracellular superoxide dismutase in renal ischemia/reperfusion injury. Schneider MP, Sullivan JC, Wach PF, Boesen EI, Yamamoto T, Fukai T, Harrison DG, Pollock DM, Pollock JS (2010) Kidney Int 78:374-81 | 2010 |
| Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. Robertson PD, Chagot B, Chazin WJ, Eichman BF (2010) J Biol Chem 285:22942-9 | 2010 |
| p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. Smalley-Freed WG, Efimov A, Burnett PE, Short SP, Davis MA, Gumucio DL, Washington MK, Coffey RJ, Reynolds AB (2010) J Clin Invest 120:1824-35 | 2010 |
| Leveraging the membrane - cytoskeleton interface with myosin-1. McConnell RE, Tyska MJ (2010) Trends Cell Biol 20:418-26 | 2010 |
| A physical model for PDZ-domain/peptide interactions. Kaufmann K, Shen N, Mizoue L, Meiler J (2011) J Mol Model 17:315-24 | 2011 |
| Therapeutic targeting of mitochondrial superoxide in hypertension. Dikalova AE, Bikineyeva AT, Budzyn K, Nazarewicz RR, McCann L, Lewis W, Harrison DG, Dikalov SI (2010) Circ Res 107:106-16 | 2010 |
| Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study. Kalogeropoulos A, Georgiopoulou V, Psaty BM, Rodondi N, Smith AL, Harrison DG, Liu Y, Hoffmann U, Bauer DC, Newman AB, Kritchevsky SB, Harris TB, Butler J, Health ABC Study Investigators (2010) J Am Coll Cardiol 55:2129-37 | 2010 |
| Increased cell migration and plasticity in Nrf2-deficient cancer cell lines. Rachakonda G, Sekhar KR, Jowhar D, Samson PC, Wikswo JP, Beauchamp RD, Datta PK, Freeman ML (2010) Oncogene 29:3703-14 | 2010 |
| Window on a microworld: simple microfluidic systems for studying microbial transport in porous media. Markov DA, Samson PC, Schaffer DK, Dhummakupt A, Wikswo JP, Shor LM (2010) J Vis Exp : | 2010 |
| LIM and SH3 protein-1 modulates CXCR2-mediated cell migration. Raman D, Sai J, Neel NF, Chew CS, Richmond A (2010) PLoS One 5:e10050 | 2010 |
| Chemokine modulation of the tumor microenvironment. Richmond A (2010) Pigment Cell Melanoma Res 23:312-3 | 2010 |
| Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening. Mueller R, Rodriguez AL, Dawson ES, Butkiewicz M, Nguyen TT, Oleszkiewicz S, Bleckmann A, Weaver CD, Lindsley CW, Conn PJ, Meiler J (2010) ACS Chem Neurosci 1:288-305 | 2010 |
| A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease. Ayati BP, Edwards CM, Webb GF, Wikswo JP (2010) Biol Direct 5:28 | 2010 |
| Genetic deletion of COX-2 diminishes VEGF production in mouse retinal Müller cells. Yanni SE, McCollum GW, Penn JS (2010) Exp Eye Res 91:34-41 | 2010 |
| Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators. Wang SE, Yu Y, Criswell TL, Debusk LM, Lin PC, Zent R, Johnson DH, Ren X, Arteaga CL (2010) Oncogene 29:3335-48 | 2010 |
| Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model. Li B, Brown KV, Wenke JC, Guelcher SA (2010) J Control Release 145:221-30 | 2010 |
| Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC. Crossno PF, Polosukhin VV, Blackwell TS, Johnson JE, Markin C, Moore PE, Worrell JA, Stahlman MT, Phillips JA, Loyd JE, Cogan JD, Lawson WE (2010) Chest 137:969-73 | 2010 |
| Exposing p120 catenin's most intimate affair. Reynolds AB (2010) Cell 141:20-2 | 2010 |
| Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A (2010) Mol Cell Biol 30:3048-58 | 2010 |
| Macula densa sensing and signaling mechanisms of renin release. Peti-Peterdi J, Harris RC (2010) J Am Soc Nephrol 21:1093-6 | 2010 |
| Not all noise is waste. Quaranta V, Garbett SP (2010) Nat Methods 7:269-72 | 2010 |
| The role of a recombinant fragment of laminin-332 in integrin alpha3beta1-dependent cell binding, spreading and migration. Yamashita H, Tripathi M, Harris MP, Liu S, Weidow B, Zent R, Quaranta V (2010) Biomaterials 31:5110-21 | 2010 |
| Sirt1 activation protects the mouse renal medulla from oxidative injury. He W, Wang Y, Zhang MZ, You L, Davis LS, Fan H, Yang HC, Fogo AB, Zent R, Harris RC, Breyer MD, Hao CM (2010) J Clin Invest 120:1056-68 | 2010 |
| Epitope mapping of function-blocking monoclonal antibody CM6 suggests a "weak" integrin binding site on the laminin-332 LG2 domain. Yamashita H, Shang M, Tripathi M, Jourquin J, Georgescu W, Liu S, Weidow B, Quaranta V (2010) J Cell Physiol 223:541-8 | 2010 |
| NADPH oxidase limits innate immune responses in the lungs in mice. Segal BH, Han W, Bushey JJ, Joo M, Bhatti Z, Feminella J, Dennis CG, Vethanayagam RR, Yull FE, Capitano M, Wallace PK, Minderman H, Christman JW, Sporn MB, Chan J, Vinh DC, Holland SM, Romani LR, Gaffen SL, Freeman ML, Blackwell TS (2010) PLoS One 5:e9631 | 2010 |
| Practically useful: what the Rosetta protein modeling suite can do for you. Kaufmann KW, Lemmon GH, Deluca SL, Sheehan JH, Meiler J (2010) Biochemistry 49:2987-98 | 2010 |
| Tie2 signaling regulates osteoclastogenesis and osteolytic bone invasion of breast cancer. Min Y, Ren X, Vaught DB, Chen J, Donnelly E, Lynch CC, Lin PC (2010) Cancer Res 70:2819-28 | 2010 |
| Human mammary epithelial cells exhibit a bimodal correlated random walk pattern. Potdar AA, Jeon J, Weaver AM, Quaranta V, Cummings PT (2010) PLoS One 5:e9636 | 2010 |
| Interleukin-32beta propagates vascular inflammation and exacerbates sepsis in a mouse model. Kobayashi H, Huang J, Ye F, Shyr Y, Blackwell TS, Lin PC (2010) PLoS One 5:e9458 | 2010 |
| Specific effects of bortezomib against experimental malignant pleural effusion: a preclinical study. Psallidas I, Karabela SP, Moschos C, Sherrill TP, Kollintza A, Magkouta S, Theodoropoulou P, Roussos C, Blackwell TS, Kalomenidis I, Stathopoulos GT (2010) Mol Cancer 9:56 | 2010 |
| Synthesis and characterization of an injectable allograft bone/polymer composite bone void filler with tunable mechanical properties. Dumas JE, Zienkiewicz K, Tanner SA, Prieto EM, Bhattacharyya S, Guelcher SA (2010) Tissue Eng Part A 16:2505-18 | 2010 |
| A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration. Yoshii T, Hafeman AE, Nyman JS, Esparza JM, Shinomiya K, Spengler DM, Mundy GR, Gutierrez GE, Guelcher SA (2010) Tissue Eng Part A 16:2369-79 | 2010 |
| The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults. Working Group of the International IgA Nephropathy Network and the Renal Pathology Society, Coppo R, Troyanov S, Camilla R, Hogg RJ, Cattran DC, Cook HT, Feehally J, Roberts IS, Amore A, Alpers CE, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D'Agati V, D'Amico G, Emancipator SN, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo AB, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H (2010) Kidney Int 77:921-7 | 2010 |
| Hedgehog signaling induces arterial endothelial cell formation by repressing venous cell fate. Williams C, Kim SH, Ni TT, Mitchell L, Ro H, Penn JS, Baldwin SH, Solnica-Krezel L, Zhong TP (2010) Dev Biol 341:196-204 | 2010 |
| Pathologic classification of diabetic nephropathy. Tervaert TW, Mooyaart AL, Amann K, Cohen AH, Cook HT, Drachenberg CB, Ferrario F, Fogo AB, Haas M, de Heer E, Joh K, Noël LH, Radhakrishnan J, Seshan SV, Bajema IM, Bruijn JA, Renal Pathology Society (2010) J Am Soc Nephrol 21:556-63 | 2010 |
| Role of the adaptive immune system in hypertension. Harrison DG, Vinh A, Lob H, Madhur MS (2010) Curr Opin Pharmacol 10:203-7 | 2010 |
| Chemokines and chemokine receptors: new insights into cancer-related inflammation. Lazennec G, Richmond A (2010) Trends Mol Med 16:133-44 | 2010 |
| Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-independent. Matsusaka T, Asano T, Niimura F, Kinomura M, Shimizu A, Shintani A, Pastan I, Fogo AB, Ichikawa I (2010) Hypertension 55:967-73 | 2010 |
| ZO-1 and ZONAB interact to regulate proximal tubular cell differentiation. Pozzi A, Zent R (2010) J Am Soc Nephrol 21:388-90 | 2010 |
| NO solution for a radical problem: a TAL story. Gongora MC, Harrison DG (2010) Am J Physiol Renal Physiol 298:F883-4 | 2010 |
| p120-Catenin is required for mouse vascular development. Oas RG, Xiao K, Summers S, Wittich KB, Chiasson CM, Martin WD, Grossniklaus HE, Vincent PA, Reynolds AB, Kowalczyk AP (2010) Circ Res 106:941-51 | 2010 |
| Synthesis, characterization, and remodeling of weight-bearing allograft bone/polyurethane composites in the rabbit. Dumas JE, Davis T, Holt GE, Yoshii T, Perrien DS, Nyman JS, Boyce T, Guelcher SA (2010) Acta Biomater 6:2394-406 | 2010 |
| Myosin motor function: the ins and outs of actin-based membrane protrusions. Nambiar R, McConnell RE, Tyska MJ (2010) Cell Mol Life Sci 67:1239-54 | 2010 |
| Differential localization and dynamics of class I myosins in the enterocyte microvillus. Benesh AE, Nambiar R, McConnell RE, Mao S, Tabb DL, Tyska MJ (2010) Mol Biol Cell 21:970-8 | 2010 |
| Assessing the application of tissue microarray technology to kidney research. Zhang MZ, Su Y, Yao B, Zheng W, Decaestecker M, Harris RC (2010) J Histochem Cytochem 58:413-20 | 2010 |
| Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction. Silberman GA, Fan TH, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC (2010) Circulation 121:519-28 | 2010 |
| The spectrum of FSGS: does pathology matter? Fogo AB (2010) Nephrol Dial Transplant 25:1034-6 | 2010 |
| 'Idiopathic' FSGS: an increasingly obsolete diagnosis? Yang HC, Fogo AB (2010) Nephrol Dial Transplant 25:654-6 | 2010 |
| An off-lattice hybrid discrete-continuum model of tumor growth and invasion. Jeon J, Quaranta V, Cummings PT (2010) Biophys J 98:37-47 | 2010 |
| Sulodexide ameliorates early but not late kidney disease in models of radiation nephropathy and diabetic nephropathy. Rossini M, Naito T, Yang H, Freeman M, Donnert E, Ma LJ, Dunn SR, Sharma K, Fogo AB (2010) Nephrol Dial Transplant 25:1803-10 | 2010 |
| GSK3beta mediates renal response to vasopressin by modulating adenylate cyclase activity. Rao R, Patel S, Hao C, Woodgett J, Harris R (2010) J Am Soc Nephrol 21:428-37 | 2010 |
| Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis. Naito T, Ma LJ, Yang H, Zuo Y, Tang Y, Han JY, Kon V, Fogo AB (2010) Am J Physiol Renal Physiol 298:F683-91 | 2010 |
| Local delivery of tobramycin from injectable biodegradable polyurethane scaffolds. Hafeman AE, Zienkiewicz KJ, Carney E, Litzner B, Stratton C, Wenke JC, Guelcher SA (2010) J Biomater Sci Polym Ed 21:95-112 | 2010 |
| Laminin-332-beta1 integrin interactions negatively regulate invadopodia. Liu S, Yamashita H, Weidow B, Weaver AM, Quaranta V (2010) J Cell Physiol 223:134-42 | 2010 |
| Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction. Madhur MS, Lob HE, McCann LA, Iwakura Y, Blinder Y, Guzik TJ, Harrison DG (2010) Hypertension 55:500-7 | 2010 |
| Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy. Zhuang G, Brantley-Sieders DM, Vaught D, Yu J, Xie L, Wells S, Jackson D, Muraoka-Cook R, Arteaga C, Chen J (2010) Cancer Res 70:299-308 | 2010 |
| A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets. Su Y, Amiri KI, Horton LW, Yu Y, Ayers GD, Koehler E, Kelley MC, Puzanov I, Richmond A, Sosman JA (2010) Clin Cancer Res 16:348-57 | 2010 |
| Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system. Lob HE, Marvar PJ, Guzik TJ, Sharma S, McCann LA, Weyand C, Gordon FJ, Harrison DG (2010) Hypertension 55:277-83, 6p following 283 | 2010 |
| Nuclear factor kappa B induction in airway epithelium increases lung inflammation in allergen-challenged mice. Sheller JR, Polosukhin VV, Mitchell D, Cheng DS, Peebles RS, Blackwell TS (2009) Exp Lung Res 35:883-95 | 2009 |
| Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells. Miller TW, Forbes JT, Shah C, Wyatt SK, Manning HC, Olivares MG, Sanchez V, Dugger TC, de Matos Granja N, Narasanna A, Cook RS, Kennedy JP, Lindsley CW, Arteaga CL (2009) Clin Cancer Res 15:7266-76 | 2009 |
| Phase 1 trial of adalimumab in Focal Segmental Glomerulosclerosis (FSGS): II. Report of the FONT (Novel Therapies for Resistant FSGS) study group. Joy MS, Gipson DS, Powell L, MacHardy J, Jennette JC, Vento S, Pan C, Savin V, Eddy A, Fogo AB, Kopp JB, Cattran D, Trachtman H (2010) Am J Kidney Dis 55:50-60 | 2010 |
| GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide. Li L, Rezvan A, Salerno JC, Husain A, Kwon K, Jo H, Harrison DG, Chen W (2010) Circ Res 106:328-36 | 2010 |
| Trait variability of cancer cells quantified by high-content automated microscopy of single cells. Quaranta V, Tyson DR, Garbett SP, Weidow B, Harris MP, Georgescu W (2009) Methods Enzymol 467:23-57 | 2009 |
| The effects of nepafenac and amfenac on retinal angiogenesis. Yanni SE, Clark ML, Yang R, Bingaman DP, Penn JS (2010) Brain Res Bull 81:310-9 | 2010 |
| Microenvironmental independence associated with tumor progression. Anderson AR, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, Basanta D, Weidow B, Narasanna A, Arteaga CL, Reynolds AB, Quaranta V, Estrada L, Weaver AM (2009) Cancer Res 69:8797-806 | 2009 |
| Tape underlayment rotary-node (TURN) valves for simple on-chip microfluidic flow control. Markov DA, Manuel S, Shor LM, Opalenik SR, Wikswo JP, Samson PC (2010) Biomed Microdevices 12:135-44 | 2010 |
| MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis. Rebustini IT, Myers C, Lassiter KS, Surmak A, Szabova L, Holmbeck K, Pedchenko V, Hudson BG, Hoffman MP (2009) Dev Cell 17:482-93 | 2009 |
| Identification of genes and pathways involved in retinal neovascularization by microarray analysis of two animal models of retinal angiogenesis. Recchia FM, Xu L, Penn JS, Boone B, Dexheimer PJ (2010) Invest Ophthalmol Vis Sci 51:1098-105 | 2010 |
| Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). Fogo AB, Bostad L, Svarstad E, Cook WJ, Moll S, Barbey F, Geldenhuys L, West M, Ferluga D, Vujkovac B, Howie AJ, Burns A, Reeve R, Waldek S, Noël LH, Grünfeld JP, Valbuena C, Oliveira JP, Müller J, Breunig F, Zhang X, Warnock DG, all members of the International Study Group of Fabry Nephropathy (ISGFN) (2010) Nephrol Dial Transplant 25:2168-77 | 2010 |
| Integrin-linked kinase is an adaptor with essential functions during mouse development. Lange A, Wickström SA, Jakobson M, Zent R, Sainio K, Fässler R (2009) Nature 461:1002-6 | 2009 |
| Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen. Marjoram RJ, Voss B, Pan Y, Dickeson SK, Zutter MM, Hamm HE, Santoro SA (2009) J Biol Chem 284:34640-7 | 2009 |
| Dystroglycan in the diagnosis of FSGS. Giannico G, Yang H, Neilson EG, Fogo AB (2009) Clin J Am Soc Nephrol 4:1747-53 | 2009 |
| The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury. Yang HC, Deleuze S, Zuo Y, Potthoff SA, Ma LJ, Fogo AB (2009) J Am Soc Nephrol 20:2380-8 | 2009 |
| Murine CENP-F regulates centrosomal microtubule nucleation and interacts with Hook2 at the centrosome. Moynihan KL, Pooley R, Miller PM, Kaverina I, Bader DM (2009) Mol Biol Cell 20:4790-803 | 2009 |
| Origin choice and petal loss in the flower garden of spiral wave tip trajectories. Gray RA, Wikswo JP, Otani NF (2009) Chaos 19:033118 | 2009 |
| Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV (2009) Blood 114:4897-906 | 2009 |
| Recurrent pauci-immune necrotizing crescentic glomerulonephritis in a kidney transplant patient. Schaefer HM, Langone A, Helderman JH, Fogo AB (2010) Am J Kidney Dis 55:604-8 | 2010 |
| BCL::contact-low confidence fold recognition hits boost protein contact prediction and de novo structure determination. Karakaş M, Woetzel N, Meiler J (2010) J Comput Biol 17:153-68 | 2010 |
| Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway. Yao B, Harris RC, Zhang MZ (2009) Hypertension 54:1077-83 | 2009 |
| The role of integrin alpha8beta1 in fetal lung morphogenesis and injury. Benjamin JT, Gaston DC, Halloran BA, Schnapp LM, Zent R, Prince LS (2009) Dev Biol 335:407-17 | 2009 |
| The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora. Li B, Yoshii T, Hafeman AE, Nyman JS, Wenke JC, Guelcher SA (2009) Biomaterials 30:6768-79 | 2009 |
| Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection. Connelly L, Barham W, Pigg R, Saint-Jean L, Sherrill T, Cheng DS, Chodosh LA, Blackwell TS, Yull FE (2010) J Cell Physiol 222:73-81 | 2010 |
| The role of chemokines in intestinal inflammation and cancer. Wang D, Dubois RN, Richmond A (2009) Curr Opin Pharmacol 9:688-96 | 2009 |
| A sulfilimine bond identified in collagen IV. Vanacore R, Ham AJ, Voehler M, Sanders CR, Conrads TP, Veenstra TD, Sharpless KB, Dawson PE, Hudson BG (2009) Science 325:1230-4 | 2009 |
| Mouse models of diabetic nephropathy. Brosius FC, Alpers CE, Bottinger EP, Breyer MD, Coffman TM, Gurley SB, Harris RC, Kakoki M, Kretzler M, Leiter EH, Levi M, McIndoe RA, Sharma K, Smithies O, Susztak K, Takahashi N, Takahashi T, Animal Models of Diabetic Complications Consortium (2009) J Am Soc Nephrol 20:2503-12 | 2009 |
| The multi-talented podocyte. Fogo AB (2009) Nephrol Dial Transplant 24:3269-70 | 2009 |
| beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity. Zhang X, Mernaugh G, Yang DH, Gewin L, Srichai MB, Harris RC, Iturregui JM, Nelson RD, Kohan DE, Abrahamson D, Fässler R, Yurchenco P, Pozzi A, Zent R (2009) Development 136:3357-66 | 2009 |
| Microfluidic single cell arrays to interrogate signalling dynamics of individual, patient-derived hematopoietic stem cells. Faley SL, Copland M, Wlodkowic D, Kolch W, Seale KT, Wikswo JP, Cooper JM (2009) Lab Chip 9:2659-64 | 2009 |
| Transmembrane and soluble isoforms of heparin-binding epidermal growth factor-like growth factor regulate distinct processes in the pancreas. Ray KC, Blaine SA, Washington MK, Braun AH, Singh AB, Harris RC, Harding PA, Coffey RJ, Means AL (2009) Gastroenterology 137:1785-94 | 2009 |
| Defining the role of laminin-332 in carcinoma. Guess CM, Quaranta V (2009) Matrix Biol 28:445-55 | 2009 |
| Renal dysfunction potentiates foam cell formation by repressing ABCA1. Zuo Y, Yancey P, Castro I, Khan WN, Khan W, Motojima M, Ichikawa I, Fogo AB, Linton MF, Fazio S, Kon V (2009) Arterioscler Thromb Vasc Biol 29:1277-82 | 2009 |
| Role of cytosolic phospholipase A(2) in retinal neovascularization. Barnett JM, McCollum GW, Penn JS (2010) Invest Ophthalmol Vis Sci 51:1136-42 | 2010 |
| The potential of dual camera systems for multimodal imaging of cardiac electrophysiology and metabolism. Holcomb MR, Woods MC, Uzelac I, Wikswo JP, Gilligan JM, Sidorov VY (2009) Exp Biol Med (Maywood) 234:1355-73 | 2009 |
| Accessing ns-micros side chain dynamics in ubiquitin with methyl RDCs. Farès C, Lakomek NA, Walter KF, Frank BT, Meiler J, Becker S, Griesinger C (2009) J Biomol NMR 45:23-44 | 2009 |
| Distinct roles for basal and induced COX-2 in podocyte injury. Cheng H, Fan X, Guan Y, Moeckel GW, Zent R, Harris RC (2009) J Am Soc Nephrol 20:1953-62 | 2009 |
| CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance. Ma LL, Gao X, Liu L, Xiang Z, Blackwell TS, Williams P, Chari RS, Yin DP (2009) Liver Transpl 15:915-23 | 2009 |
| The development of the rat model of retinopathy of prematurity. Barnett JM, Yanni SE, Penn JS (2010) Doc Ophthalmol 120:3-12 | 2010 |
| Computational predictions of the tensile properties of electrospun fibre meshes: effect of fibre diameter and fibre orientation. Stylianopoulos T, Bashur CA, Goldstein AS, Guelcher SA, Barocas VH (2008) J Mech Behav Biomed Mater 1:326-35 | 2008 |
| Autoimmune pancreatitis results from loss of TGFbeta signalling in S100A4-positive dendritic cells. Boomershine CS, Chamberlain A, Kendall P, Afshar-Sharif AR, Huang H, Washington MK, Lawson WE, Thomas JW, Blackwell TS, Bhowmick NA (2009) Gut 58:1267-74 | 2009 |
| Physical interactions between Mcm10, DNA, and DNA polymerase alpha. Warren EM, Huang H, Fanning E, Chazin WJ, Eichman BF (2009) J Biol Chem 284:24662-72 | 2009 |
| Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions. Pozzi A, Zent R, Chetyrkin S, Borza C, Bulus N, Chuang P, Chen D, Hudson B, Voziyan P (2009) J Am Soc Nephrol 20:2119-25 | 2009 |
| EM-fold: De novo folding of alpha-helical proteins guided by intermediate-resolution electron microscopy density maps. Lindert S, Staritzbichler R, Wötzel N, Karakaş M, Stewart PL, Meiler J (2009) Structure 17:990-1003 | 2009 |
| Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements. Kam Y, Karperien A, Weidow B, Estrada L, Anderson AR, Quaranta V (2009) BMC Res Notes 2:130 | 2009 |
| Concurrent and discrete clinicopathological presentations of Wegener granulomatosis and anti-glomerular basement membrane disease. Clyne S, Frederick C, Arndt F, Lewis J, Fogo AB (2009) Am J Kidney Dis 54:1116-20 | 2009 |
| Control of cell membrane tension by myosin-I. Nambiar R, McConnell RE, Tyska MJ (2009) Proc Natl Acad Sci U S A 106:11972-7 | 2009 |
| The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Working Group of the International IgA Nephropathy Network and the Renal Pathology Society, Cattran DC, Coppo R, Cook HT, Feehally J, Roberts IS, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D'Agati V, D'Amico G, Emancipator S, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Leung CB, Li LS, Li PK, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H (2009) Kidney Int 76:534-45 | 2009 |
| The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. Working Group of the International IgA Nephropathy Network and the Renal Pathology Society, Roberts IS, Cook HT, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, Cattran DC, Coppo R, D'Agati V, D'Amico G, Emancipator S, Emma F, Feehally J, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H (2009) Kidney Int 76:546-56 | 2009 |
| A spatial model of tumor-host interaction: application of chemotherapy. Hinow P, Gerlee P, McCawley LJ, Quaranta V, Ciobanu M, Wang S, Graham JM, Ayati BP, Claridge J, Swanson KR, Loveless M, Anderson AR (2009) Math Biosci Eng 6:521-46 | 2009 |
| The enterocyte microvillus is a vesicle-generating organelle. McConnell RE, Higginbotham JN, Shifrin DA, Tabb DL, Coffey RJ, Tyska MJ (2009) J Cell Biol 185:1285-98 | 2009 |
| Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Tanjore H, Xu XC, Polosukhin VV, Degryse AL, Li B, Han W, Sherrill TP, Plieth D, Neilson EG, Blackwell TS, Lawson WE (2009) Am J Respir Crit Care Med 180:657-65 | 2009 |
| Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase. Van Horn WD, Kim HJ, Ellis CD, Hadziselimovic A, Sulistijo ES, Karra MD, Tian C, Sönnichsen FD, Sanders CR (2009) Science 324:1726-9 | 2009 |
| Pyridoxamine protects intestinal epithelium from ionizing radiation-induced apoptosis. Thotala D, Chetyrkin S, Hudson B, Hallahan D, Voziyan P, Yazlovitskaya E (2009) Free Radic Biol Med 47:779-85 | 2009 |
| Partial independence of bioelectric and biomagnetic fields and its implications for encephalography and cardiography. Irimia A, Swinney KR, Wikswo JP (2009) Phys Rev E Stat Nonlin Soft Matter Phys 79:051908 | 2009 |
| Microfluidic single-cell array cytometry for the analysis of tumor apoptosis. Wlodkowic D, Faley S, Zagnoni M, Wikswo JP, Cooper JM (2009) Anal Chem 81:5517-23 | 2009 |
| The role of PGE2 receptor EP4 in pathologic ocular angiogenesis. Yanni SE, Barnett JM, Clark ML, Penn JS (2009) Invest Ophthalmol Vis Sci 50:5479-86 | 2009 |
| A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family. Friedland GD, Lakomek NA, Griesinger C, Meiler J, Kortemme T (2009) PLoS Comput Biol 5:e1000393 | 2009 |
| S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy. Chen JK, Chen J, Thomas G, Kozma SC, Harris RC (2009) Am J Physiol Renal Physiol 297:F585-93 | 2009 |
| Reduction of renal superoxide dismutase in progressive diabetic nephropathy. Fujita H, Fujishima H, Chida S, Takahashi K, Qi Z, Kanetsuna Y, Breyer MD, Harris RC, Yamada Y, Takahashi T (2009) J Am Soc Nephrol 20:1303-13 | 2009 |
| Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). Engers DW, Niswender CM, Weaver CD, Jadhav S, Menon UN, Zamorano R, Conn PJ, Lindsley CW, Hopkins CR (2009) J Med Chem 52:4115-8 | 2009 |
| Differential gene expression in normal esophagus and Barrett's esophagus. Wang J, Qin R, Ma Y, Wu H, Peters H, Tyska M, Shaheen NJ, Chen X (2009) J Gastroenterol 44:897-911 | 2009 |
| Monitoring NF-kappaB mediated chemokine transcription in tumorigenesis. Yang J, Richmond AJ (2009) Methods Enzymol 460:347-55 | 2009 |
| Characterization of chemokine receptor CXCR2 interacting proteins using a proteomics approach to define the CXCR2 "chemosynapse". Raman D, Neel NF, Sai J, Mernaugh RL, Ham AJ, Richmond AJ (2009) Methods Enzymol 460:315-30 | 2009 |
| The tail of integrins, talin, and kindlins. Moser M, Legate KR, Zent R, Fässler R (2009) Science 324:895-9 | 2009 |
| Discovery and SAR of novel mGluR5 non-competitive antagonists not based on an MPEP chemotype. Rodriguez AL, Williams R, Zhou Y, Lindsley SR, Le U, Grier MD, Weaver CD, Conn PJ, Lindsley CW (2009) Bioorg Med Chem Lett 19:3209-13 | 2009 |
| A novel class of H3 antagonists derived from the natural product guided synthesis of unnatural analogs of the marine bromopyrrole alkaloid dispyrin. Kennedy JP, Conn PJ, Lindsley CW (2009) Bioorg Med Chem Lett 19:3204-8 | 2009 |
| Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins. Bridges TM, Marlo JE, Niswender CM, Jones CK, Jadhav SB, Gentry PR, Plumley HC, Weaver CD, Conn PJ, Lindsley CW (2009) J Med Chem 52:3445-8 | 2009 |
| Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG. Sadagopal S, Braunstein M, Hager CC, Wei J, Daniel AK, Bochan MR, Crozier I, Smith NE, Gates HO, Barnett L, Van Kaer L, Price JO, Blackwell TS, Kalams SA, Kernodle DS (2009) PLoS One 4:e5531 | 2009 |
| Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer. Miller TW, Pérez-Torres M, Narasanna A, Guix M, Stål O, Pérez-Tenorio G, Gonzalez-Angulo AM, Hennessy BT, Mills GB, Kennedy JP, Lindsley CW, Arteaga CL (2009) Cancer Res 69:4192-201 | 2009 |
| Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo. Brantley-Sieders DM, Zhuang G, Vaught D, Freeman T, Hwang Y, Hicks D, Chen J (2009) Mol Cancer Res 7:615-23 | 2009 |
| VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis. Neel NF, Barzik M, Raman D, Sobolik-Delmaire T, Sai J, Ham AJ, Mernaugh RL, Gertler FB, Richmond A (2009) J Cell Sci 122:1882-94 | 2009 |
| Oxidative stress and hypertension. Harrison DG, Gongora MC (2009) Med Clin North Am 93:621-35 | 2009 |
| Cellular origins of type IV collagen networks in developing glomeruli. Abrahamson DR, Hudson BG, Stroganova L, Borza DB, St John PL (2009) J Am Soc Nephrol 20:1471-9 | 2009 |
| Development of animal models for the acute respiratory distress syndrome. Bastarache JA, Blackwell TS (2009) Dis Model Mech 2:218-23 | 2009 |
| A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning. Sheffler DJ, Williams R, Bridges TM, Xiang Z, Kane AS, Byun NE, Jadhav S, Mock MM, Zheng F, Lewis LM, Jones CK, Niswender CM, Weaver CD, Lindsley CW, Conn PJ (2009) Mol Pharmacol 76:356-68 | 2009 |
| The evolutionarily conserved residue A653 plays a key role in HERG channel closing. Stepanovic SZ, Potet F, Petersen CI, Smith JA, Meiler J, Balser JR, Kupershmidt S (2009) J Physiol 587:2555-66 | 2009 |
| A decreased ratio of laminin-332 beta3 to gamma2 subunit mRNA is associated with poor prognosis in colon cancer. Guess CM, Lafleur BJ, Weidow BL, Quaranta V (2009) Cancer Epidemiol Biomarkers Prev 18:1584-90 | 2009 |
| Regulation of matrix synthesis, remodeling and accumulation in glomerulosclerosis. Pozzi A, Voziyan PA, Hudson BG, Zent R (2009) Curr Pharm Des 15:1318-33 | 2009 |
| Hybrid approaches: applying computational methods in cryo-electron microscopy. Lindert S, Stewart PL, Meiler J (2009) Curr Opin Struct Biol 19:218-25 | 2009 |
| The effect of the local delivery of platelet-derived growth factor from reactive two-component polyurethane scaffolds on the healing in rat skin excisional wounds. Li B, Davidson JM, Guelcher SA (2009) Biomaterials 30:3486-94 | 2009 |
| Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase. Vaught D, Chen J, Brantley-Sieders DM (2009) Mol Biol Cell 20:2572-81 | 2009 |
| Micro-mirrors for nanoscale three-dimensional microscopy. Seale K, Janetopoulos C, Wikswo J (2009) ACS Nano 3:493-7 | 2009 |
| Inhibition of 11beta-hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans. Zhang MZ, Xu J, Yao B, Yin H, Cai Q, Shrubsole MJ, Chen X, Kon V, Zheng W, Pozzi A, Harris RC (2009) J Clin Invest 119:876-85 | 2009 |
| Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity. Lavieri R, Scott SA, Lewis JA, Selvy PE, Armstrong MD, Alex Brown H, Lindsley CW (2009) Bioorg Med Chem Lett 19:2240-3 | 2009 |
| mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Ayala JE, Chen Y, Banko JL, Sheffler DJ, Williams R, Telk AN, Watson NL, Xiang Z, Zhang Y, Jones PJ, Lindsley CW, Olive MF, Conn PJ (2009) Neuropsychopharmacology 34:2057-71 | 2009 |
| Effect of fiber diameter and alignment of electrospun polyurethane meshes on mesenchymal progenitor cells. Bashur CA, Shaffer RD, Dahlgren LA, Guelcher SA, Goldstein AS (2009) Tissue Eng Part A 15:2435-45 | 2009 |
| Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2. Delpire E, Days E, Lewis LM, Mi D, Kim K, Lindsley CW, Weaver CD (2009) Proc Natl Acad Sci U S A 106:5383-8 | 2009 |
| Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy. Yang J, Zaja-Milatovic S, Thu YM, Lee F, Smykla R, Richmond A (2009) Mol Cancer Ther 8:636-47 | 2009 |
| PAI-1 and kidney fibrosis. Ma LJ, Fogo AB (2009) Front Biosci (Landmark Ed) 14:2028-41 | 2009 |
| Migration of isogenic cell lines quantified by dynamic multivariate analysis of single-cell motility. Harris MP, Kim E, Weidow B, Wikswo JP, Quaranta V (2008) Cell Adh Migr 2:127-36 | 2008 |
| Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity. Lewis JA, Scott SA, Lavieri R, Buck JR, Selvy PE, Stoops SL, Armstrong MD, Brown HA, Lindsley CW (2009) Bioorg Med Chem Lett 19:1916-20 | 2009 |
| Negative regulation of activated alpha-2 integrins during thrombopoiesis. Zou Z, Schmaier AA, Cheng L, Mericko P, Dickeson SK, Stricker TP, Santoro SA, Kahn ML (2009) Blood 113:6428-39 | 2009 |
| Soluble HB-EGF induces epithelial-to-mesenchymal transition in inner medullary collecting duct cells by upregulating Snail-2. Smith JP, Pozzi A, Dhawan P, Singh AB, Harris RC (2009) Am J Physiol Renal Physiol 296:F957-65 | 2009 |
| Molecule of the month. FDA approves new treatment for fibromyalgia. Lindsley CW (2009) Curr Top Med Chem 9:225 | 2009 |
| Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools. Kam Y, Quaranta V (2009) PLoS One 4:e4580 | 2009 |
| Solvent accessible surface area approximations for rapid and accurate protein structure prediction. Durham E, Dorr B, Woetzel N, Staritzbichler R, Meiler J (2009) J Mol Model 15:1093-108 | 2009 |
| Selective binding of integrins from different renal cell types to the NC1 domain of alpha3 and alpha1 chains of type IV collagen. Aggeli AS, Kitsiou PV, Tzinia AK, Boutaud A, Hudson BG, Tsilibary EC (2009) J Nephrol 22:130-6 | 2009 |
| Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt. Lea WB, Kwak ES, Luther JM, Fowler SM, Wang Z, Ma J, Fogo AB, Brown NJ (2009) Kidney Int 75:936-44 | 2009 |
| The good and the bad of chemokines/chemokine receptors in melanoma. Richmond A, Yang J, Su Y (2009) Pigment Cell Melanoma Res 22:175-86 | 2009 |
| The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating. Fallen K, Banerjee S, Sheehan J, Addison D, Lewis LM, Meiler J, Denton JS (2009) Channels (Austin) 3:57-68 | 2009 |
| Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Conn PJ, Jones CK, Lindsley CW (2009) Trends Pharmacol Sci 30:148-55 | 2009 |
| Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. Engers DW, Rodriguez AL, Williams R, Hammond AS, Venable D, Oluwatola O, Sulikowski GA, Conn PJ, Lindsley CW (2009) ChemMedChem 4:505-11 | 2009 |
| Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells. Zeng F, Xu J, Harris RC (2009) FASEB J 23:1935-45 | 2009 |
| An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth. Dohn MR, Brown MV, Reynolds AB (2009) J Cell Biol 184:437-50 | 2009 |
| Rapid, general access to chiral beta-fluoroamines and beta,beta-difluoroamines via organocatalysis. Fadeyi OO, Lindsley CW (2009) Org Lett 11:943-6 | 2009 |
| Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton. Wang SE, Xiang B, Zent R, Quaranta V, Pozzi A, Arteaga CL (2009) Cancer Res 69:475-82 | 2009 |
| Eph receptors in breast cancer: roles in tumor promotion and tumor suppression. Vaught D, Brantley-Sieders DM, Chen J (2008) Breast Cancer Res 10:217 | 2008 |
| Intrarenal dopaminergic system regulates renin expression. Zhang MZ, Yao B, Fang X, Wang S, Smith JP, Harris RC (2009) Hypertension 53:564-70 | 2009 |
| Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Scott SA, Selvy PE, Buck JR, Cho HP, Criswell TL, Thomas AL, Armstrong MD, Arteaga CL, Lindsley CW, Brown HA (2009) Nat Chem Biol 5:108-17 | 2009 |
| Universal serial bus powered and controlled isolated constant-current physiological stimulator. Holcomb MR, Bekele RY, Lima EA, Wikswo JP (2008) Rev Sci Instrum 79:126103 | 2008 |
| Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders. Conn PJ, Christopoulos A, Lindsley CW (2009) Nat Rev Drug Discov 8:41-54 | 2009 |
| Stem cell therapy for Alport syndrome: the hope beyond the hype. Gross O, Borza DB, Anders HJ, Licht C, Weber M, Segerer S, Torra R, Gubler MC, Heidet L, Harvey S, Cosgrove D, Lees G, Kashtan C, Gregory M, Savige J, Ding J, Thorner P, Abrahamson DR, Antignac C, Tryggvason K, Hudson B, Miner JH (2009) Nephrol Dial Transplant 24:731-4 | 2009 |
| Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA. Jones R, Baker MB, Weber M, Harrison DG, Bao G, Searles CD (2009) Am J Physiol Cell Physiol 296:C498-504 | 2009 |
| Myeloid cells control termination of lung inflammation through the NF-kappaB pathway. Han W, Joo M, Everhart MB, Christman JW, Yull FE, Blackwell TS (2009) Am J Physiol Lung Cell Mol Physiol 296:L320-7 | 2009 |
| Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-lead. Williams R, Niswender CM, Luo Q, Le U, Conn PJ, Lindsley CW (2009) Bioorg Med Chem Lett 19:962-6 | 2009 |
| Molecule of the month. The 'skinny' on CB1 antagonists/inverse agonists: controversial obesity drugs will not go to FDA for approval. Lindsley CW (2008) Curr Top Med Chem 8:1553 | 2008 |
| A unified hydrophobicity scale for multispan membrane proteins. Koehler J, Woetzel N, Staritzbichler R, Sanders CR, Meiler J (2009) Proteins 76:13-29 | 2009 |
| Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis. Bogan C, Chen J, O'Sullivan MG, Cormier RT (2009) Int J Cancer 124:1366-71 | 2009 |
| Structural basis for DNA binding by replication initiator Mcm10. Warren EM, Vaithiyalingam S, Haworth J, Greer B, Bielinsky AK, Chazin WJ, Eichman BF (2008) Structure 16:1892-901 | 2008 |
| Eph receptors and Ephrins in cancer: common themes and controversies. Chen J, Zhuang G, Frieden L, Debinski W (2008) Cancer Res 68:10031-3 | 2008 |
| Regulation of T-cell function by endogenously produced angiotensin II. Hoch NE, Guzik TJ, Chen W, Deans T, Maalouf SA, Gratze P, Weyand C, Harrison DG (2009) Am J Physiol Regul Integr Comp Physiol 296:R208-16 | 2009 |
| Phase I trial of rosiglitazone in FSGS: I. Report of the FONT Study Group. Joy MS, Gipson DS, Dike M, Powell L, Thompson A, Vento S, Eddy A, Fogo AB, Kopp JB, Cattran D, Trachtman H (2009) Clin J Am Soc Nephrol 4:39-47 | 2009 |
| The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity. Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ, Segerer S, Nibbs RJ, Rot A (2009) Nat Immunol 10:101-8 | 2009 |
| Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia. Conn PJ, Lindsley CW, Jones CK (2009) Trends Pharmacol Sci 30:25-31 | 2009 |
| Design of potent GlyT1 inhibitors: in vitro and in vivo profiles. Bridges TM, Williams R, Lindsley CW (2008) Curr Opin Mol Ther 10:591-601 | 2008 |
| Mouse xenograft models vs GEM models for human cancer therapeutics. Richmond A, Su Y (2008) Dis Model Mech 1:78-82 | 2008 |
| Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity. Marlo JE, Niswender CM, Days EL, Bridges TM, Xiang Y, Rodriguez AL, Shirey JK, Brady AE, Nalywajko T, Luo Q, Austin CA, Williams MB, Kim K, Williams R, Orton D, Brown HA, Lindsley CW, Weaver CD, Conn PJ (2009) Mol Pharmacol 75:577-88 | 2009 |
| Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease. Guzik TJ, Chen W, Gongora MC, Guzik B, Lob HE, Mangalat D, Hoch N, Dikalov S, Rudzinski P, Kapelak B, Sadowski J, Harrison DG (2008) J Am Coll Cardiol 52:1803-9 | 2008 |
| Residual dipolar couplings as a tool to study molecular recognition of ubiquitin. Lakomek NA, Lange OF, Walter KF, Farès C, Egger D, Lunkenheimer P, Meiler J, Grubmüller H, Becker S, de Groot BL, Griesinger C (2008) Biochem Soc Trans 36:1433-7 | 2008 |
| Mirrored pyramidal wells for simultaneous multiple vantage point microscopy. Seale KT, Reiserer RS, Markov DA, Ges IA, Wright C, Janetopoulos C, Wikswo JP (2008) J Microsc 232:1-6 | 2008 |
| Thrombotic microangiopathy and other glomerular disorders in the HIV-infected patient. Fine DM, Fogo AB, Alpers CE (2008) Semin Nephrol 28:545-55 | 2008 |
| PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway. Brown MV, Burnett PE, Denning MF, Reynolds AB (2009) Exp Cell Res 315:39-49 | 2009 |
| Obesity-related focal and segmental glomerulosclerosis: normalization of proteinuria in an adolescent after bariatric surgery. Fowler SM, Kon V, Ma L, Richards WO, Fogo AB, Hunley TE (2009) Pediatr Nephrol 24:851-5 | 2009 |
| Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy. Kang JS, Colon S, Hellmark T, Sado Y, Hudson BG, Borza DB (2008) J Biol Chem 283:35070-7 | 2008 |
| Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. Que J, Wilm B, Hasegawa H, Wang F, Bader D, Hogan BL (2008) Proc Natl Acad Sci U S A 105:16626-30 | 2008 |
| A novel role for activating transcription factor-2 in 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis. Zhao T, Wang D, Cheranov SY, Karpurapu M, Chava KR, Kundumani-Sridharan V, Johnson DA, Penn JS, Rao GN (2009) J Lipid Res 50:521-33 | 2009 |
| Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. Jones CK, Brady AE, Davis AA, Xiang Z, Bubser M, Tantawy MN, Kane AS, Bridges TM, Kennedy JP, Bradley SR, Peterson TE, Ansari MS, Baldwin RM, Kessler RM, Deutch AY, Lah JJ, Levey AI, Lindsley CW, Conn PJ (2008) J Neurosci 28:10422-33 | 2008 |
| Microenvironment driven invasion: a multiscale multimodel investigation. Anderson AR, Rejniak KA, Gerlee P, Quaranta V (2009) J Math Biol 58:579-624 | 2009 |
| Structure and DNA binding of alkylation response protein AidB. Bowles T, Metz AH, O'Quin J, Wawrzak Z, Eichman BF (2008) Proc Natl Acad Sci U S A 105:15299-304 | 2008 |
| Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen. Miller NR, Daniels RN, Bridges TM, Brady AE, Conn PJ, Lindsley CW (2008) Bioorg Med Chem Lett 18:5443-7 | 2008 |
| Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport. Pooley RD, Moynihan KL, Soukoulis V, Reddy S, Francis R, Lo C, Ma LJ, Bader DM (2008) J Cell Sci 121:3413-21 | 2008 |
| Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel. Faley S, Seale K, Hughey J, Schaffer DK, VanCompernolle S, McKinney B, Baudenbacher F, Unutmaz D, Wikswo JP (2008) Lab Chip 8:1700-12 | 2008 |
| Cross-talk between integrins alpha1beta1 and alpha2beta1 in renal epithelial cells. Abair TD, Sundaramoorthy M, Chen D, Heino J, Ivaska J, Hudson BG, Sanders CR, Pozzi A, Zent R (2008) Exp Cell Res 314:3593-604 | 2008 |
| Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties. Bridges TM, Brady AE, Kennedy JP, Daniels RN, Miller NR, Kim K, Breininger ML, Gentry PR, Brogan JT, Jones CK, Conn PJ, Lindsley CW (2008) Bioorg Med Chem Lett 18:5439-42 | 2008 |
| Proteomic analysis of the retina: removal of RPE alters outer segment assembly and retinal protein expression. Wang X, Nookala S, Narayanan C, Giorgianni F, Beranova-Giorgianni S, McCollum G, Gerling I, Penn JS, Jablonski MM (2009) Glia 57:380-92 | 2009 |
| Total synthesis and biological evaluation of the marine bromopyrrole alkaloid dispyrin: elucidation of discrete molecular targets with therapeutic potential. Kennedy JP, Brogan JT, Lindsley CW (2008) J Nat Prod 71:1783-6 | 2008 |
| Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Niswender CM, Lebois EP, Luo Q, Kim K, Muchalski H, Yin H, Conn PJ, Lindsley CW (2008) Bioorg Med Chem Lett 18:5626-30 | 2008 |
| Tumor necrosis factor (TNF) blockers ignite FDA inquiry over cancer concerns. Lindsley CW (2008) Curr Top Med Chem 8:1158 | 2008 |
| Total synthesis of Ciliatamides A-C: stereochemical revision and the natural product-guided synthesis of unnatural analogs. Lewis JA, Daniels RN, Lindsley CW (2008) Org Lett 10:4545-8 | 2008 |
| CXC chemokines and their receptors: a case for a significant biological role in cutaneous wound healing. Zaja-Milatovic S, Richmond A (2008) Histol Histopathol 23:1399-407 | 2008 |
| Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression. Tripathi M, Nandana S, Yamashita H, Ganesan R, Kirchhofer D, Quaranta V (2008) J Biol Chem 283:30576-84 | 2008 |
| Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats. Brady AE, Jones CK, Bridges TM, Kennedy JP, Thompson AD, Heiman JU, Breininger ML, Gentry PR, Yin H, Jadhav SB, Shirey JK, Conn PJ, Lindsley CW (2008) J Pharmacol Exp Ther 327:941-53 | 2008 |
| The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology. Zeng F, Singh AB, Harris RC (2009) Exp Cell Res 315:602-10 | 2009 |
| The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxis. Baugher PJ, Richmond A (2008) J Biol Chem 283:30868-78 | 2008 |
| A new catalytic Cu(II)/sparteine oxidant system for beta,beta-phenolic couplings of styrenyl phenols: synthesis of carpanone and unnatural analogs. Daniels RN, Fadeyi OO, Lindsley CW (2008) Org Lett 10:4097-100 | 2008 |
| Extracellular matrix rigidity promotes invadopodia activity. Alexander NR, Branch KM, Parekh A, Clark ES, Iwueke IC, Guelcher SA, Weaver AM (2008) Curr Biol 18:1295-1299 | 2008 |
| Polarity reversal lowers activation time during diastolic field stimulation of the rabbit ventricles: insights into mechanisms. Maleckar MM, Woods MC, Sidorov VY, Holcomb MR, Mashburn DN, Wikswo JP, Trayanova NA (2008) Am J Physiol Heart Circ Physiol 295:H1626-33 | 2008 |
| Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies. Kaufmann KW, Dawson ES, Henry LK, Field JR, Blakely RD, Meiler J (2009) Proteins 74:630-42 | 2009 |
| Single amino acid substitution in aquaporin 11 causes renal failure. Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachman S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, Breyer MD (2008) J Am Soc Nephrol 19:1955-64 | 2008 |
| The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth. Jin RJ, Lho Y, Connelly L, Wang Y, Yu X, Saint Jean L, Case TC, Ellwood-Yen K, Sawyers CL, Bhowmick NA, Blackwell TS, Yull FE, Matusik RJ (2008) Cancer Res 68:6762-9 | 2008 |
| Molecule of the month. Lindsley CW (2008) Curr Top Med Chem 8:1100 | 2008 |
| Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Ras-mediated transformation of mammary epithelial cells. Erdogan M, Pozzi A, Bhowmick N, Moses HL, Zent R (2008) Cancer Res 68:6224-31 | 2008 |
| Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer. Macias-Perez I, Borza C, Chen X, Yan X, Ibanez R, Mernaugh G, Matrisian LM, Zent R, Pozzi A (2008) Cancer Res 68:6127-35 | 2008 |
| 3'-phosphoinositides regulate the coordination of speed and accuracy during chemotaxis. Gruver JS, Wikswo JP, Chung CY (2008) Biophys J 95:4057-67 | 2008 |
| A new multi-gram synthetic route to labeling precursors for the D(2/3) PET agent 18F-fallypride. Kim K, Miller NR, Sulikowski GA, Lindsley CW (2008) Bioorg Med Chem Lett 18:4467-9 | 2008 |
| Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL, Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB, Ayala JE, Williams R, Lindsley CW, Conn PJ (2008) Mol Pharmacol 74:1345-58 | 2008 |
| Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c. Han BG, Hao CM, Tchekneva EE, Wang YY, Lee CA, Ebrahim B, Harris RC, Kern TS, Wasserman DH, Breyer MD, Qi Z (2008) Am J Physiol Endocrinol Metab 295:E981-6 | 2008 |
| Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis. Sai J, Raman D, Liu Y, Wikswo J, Richmond A (2008) J Biol Chem 283:26538-47 | 2008 |
| p120 and Kaiso regulate Helicobacter pylori-induced expression of matrix metalloproteinase-7. Ogden SR, Wroblewski LE, Weydig C, Romero-Gallo J, O'Brien DP, Israel DA, Krishna US, Fingleton B, Reynolds AB, Wessler S, Peek RM (2008) Mol Biol Cell 19:4110-21 | 2008 |
| Vascular endothelial growth factor in eye disease. Penn JS, Madan A, Caldwell RB, Bartoli M, Caldwell RW, Hartnett ME (2008) Prog Retin Eye Res 27:331-71 | 2008 |
| G-protein-coupled receptors: from classical modes of modulation to allosteric mechanisms. Bridges TM, Lindsley CW (2008) ACS Chem Biol 3:530-41 | 2008 |
| Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells. Abair TD, Bulus N, Borza C, Sundaramoorthy M, Zent R, Pozzi A (2008) Blood 112:3242-54 | 2008 |
| The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection. Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS (2008) Clin Exp Immunol 153:420-8 | 2008 |
| Effects of unipolar stimulation on voltage and calcium distributions in the isolated rabbit heart. Sidorov VY, Holcomb MR, Woods MC, Gray RA, Wikswo JP (2008) Basic Res Cardiol 103:537-51 | 2008 |
| A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro. Kam Y, Guess C, Estrada L, Weidow B, Quaranta V (2008) BMC Cancer 8:198 | 2008 |
| Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel. Kang C, Tian C, Sönnichsen FD, Smith JA, Meiler J, George AL, Vanoye CG, Kim HJ, Sanders CR (2008) Biochemistry 47:7999-8006 | 2008 |
| Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors. Chen JK, Chen J, Imig JD, Wei S, Hachey DL, Guthi JS, Falck JR, Capdevila JH, Harris RC (2008) J Biol Chem 283:24514-24 | 2008 |
| BCL::Align-sequence alignment and fold recognition with a custom scoring function online. Dong E, Smith J, Heinze S, Alexander N, Meiler J (2008) Gene 422:41-6 | 2008 |
| A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glycosylase AlkD. Rubinson EH, Metz AH, O'Quin J, Eichman BF (2008) J Mol Biol 381:13-23 | 2008 |
| Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Lange OF, Lakomek NA, Farès C, Schröder GF, Walter KF, Becker S, Meiler J, Grubmüller H, Griesinger C, de Groot BL (2008) Science 320:1471-5 | 2008 |
| Synthesis and SAR of a mGluR5 allosteric partial antagonist lead: unexpected modulation of pharmacology with slight structural modifications to a 5-(phenylethynyl)pyrimidine scaffold. Sharma S, Rodriguez AL, Conn PJ, Lindsley CW (2008) Bioorg Med Chem Lett 18:4098-101 | 2008 |
| A model for the solution structure of the rod arrestin tetramer. Hanson SM, Dawson ES, Francis DJ, Van Eps N, Klug CS, Hubbell WL, Meiler J, Gurevich VV (2008) Structure 16:924-34 | 2008 |
| Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity. Smith TK, Hager HA, Francis R, Kilkenny DM, Lo CW, Bader DM (2008) Proc Natl Acad Sci U S A 105:8298-303 | 2008 |
| Invasion emerges from cancer cell adaptation to competitive microenvironments: quantitative predictions from multiscale mathematical models. Quaranta V, Rejniak KA, Gerlee P, Anderson AR (2008) Semin Cancer Biol 18:338-48 | 2008 |
| Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics. Lakomek NA, Walter KF, Farès C, Lange OF, de Groot BL, Grubmüller H, Brüschweiler R, Munk A, Becker S, Meiler J, Griesinger C (2008) J Biomol NMR 41:139-55 | 2008 |
| Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration. Hafeman AE, Li B, Yoshii T, Zienkiewicz K, Davidson JM, Guelcher SA (2008) Pharm Res 25:2387-99 | 2008 |
| Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence. Enderling H, Alexander NR, Clark ES, Branch KM, Estrada L, Crooke C, Jourquin J, Lobdell N, Zaman MH, Guelcher SA, Anderson AR, Weaver AM (2008) Biophys J 95:2203-18 | 2008 |
| Short tail with skin lesion phenotype occurs in transgenic mice with keratin-14 promoter-directed expression of mutant CXCR2. Yu Y, Su Y, Opalenik SR, Sobolik-Delmaire T, Neel NF, Zaja-Milatovic S, Short ST, Sai J, Richmond A (2008) J Leukoc Biol 84:406-19 | 2008 |
| A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes. Vanacore RM, Ham AJ, Cartailler JP, Sundaramoorthy M, Todd P, Pedchenko V, Sado Y, Borza DB, Hudson BG (2008) J Biol Chem 283:22737-48 | 2008 |
| Apoptosis of the thick ascending limb results in acute kidney injury. Srichai MB, Hao C, Davis L, Golovin A, Zhao M, Moeckel G, Dunn S, Bulus N, Harris RC, Zent R, Breyer MD (2008) J Am Soc Nephrol 19:1538-46 | 2008 |
| Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. Musiek ES, Brooks JD, Joo M, Brunoldi E, Porta A, Zanoni G, Vidari G, Blackwell TS, Montine TJ, Milne GL, McLaughlin B, Morrow JD (2008) J Biol Chem 283:19927-35 | 2008 |
| Genetic determination of the role of PU.1 in macrophage gene expression. Joo M, Kwon M, Azim AC, Sadikot RT, Blackwell TS, Christman JW (2008) Biochem Biophys Res Commun 372:97-102 | 2008 |
| Kindlin-2 controls bidirectional signaling of integrins. Montanez E, Ussar S, Schifferer M, Bösl M, Zent R, Moser M, Fässler R (2008) Genes Dev 22:1325-30 | 2008 |
| Integrins, extracellular matrix, and terminal differentiation of renal epithelial cells. Pozzi A, Zent R (2008) J Am Soc Nephrol 19:1043-4 | 2008 |
| Biodegradable polyurethanes: synthesis and applications in regenerative medicine. Guelcher SA (2008) Tissue Eng Part B Rev 14:3-17 | 2008 |
| Measurement techniques for cellular biomechanics in vitro. Addae-Mensah KA, Wikswo JP (2008) Exp Biol Med (Maywood) 233:792-809 | 2008 |
| Gastrointestinal arrhythmias are associated with statistically significant fluctuations in systemic information dimension. Irimia A, Wikswo JP (2008) Physiol Meas 29:N33-40 | 2008 |
| Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development. Granero-Moltó F, Sarmah S, O'Rear L, Spagnoli A, Abrahamson D, Saus J, Hudson BG, Knapik EW (2008) J Biol Chem 283:20495-504 | 2008 |
| Potential for peroxisome proliferator-activated receptor-gamma agonists in progression: beyond metabolism. Fogo AB (2008) Curr Opin Nephrol Hypertens 17:282-5 | 2008 |
| Is Zetia a 'do nothing' drug? Lindsley CW (2008) Curr Top Med Chem 8:434 | 2008 |
| Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Lawson WE, Crossno PF, Polosukhin VV, Roldan J, Cheng DS, Lane KB, Blackwell TR, Xu C, Markin C, Ware LB, Miller GG, Loyd JE, Blackwell TS (2008) Am J Physiol Lung Cell Mol Physiol 294:L1119-26 | 2008 |
| Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase. Fang WB, Brantley-Sieders DM, Hwang Y, Ham AJ, Chen J (2008) J Biol Chem 283:16017-26 | 2008 |
| Propagation of protein glycation damage involves modification of tryptophan residues via reactive oxygen species: inhibition by pyridoxamine. Chetyrkin SV, Mathis ME, Ham AJ, Hachey DL, Hudson BG, Voziyan PA (2008) Free Radic Biol Med 44:1276-85 | 2008 |
| Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation. Ma L, Xiang Z, Sherrill TP, Wang L, Blackwell TS, Williams P, Chong A, Chari R, Yin DP (2008) Transplantation 85:903-10 | 2008 |
| A microfabricated nanocalorimeter: design, characterization, and chemical calibration. Xu J, Reiserer R, Tellinghuisen J, Wikswo JP, Baudenbacher FJ (2008) Anal Chem 80:2728-33 | 2008 |
| The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells. Dhawan P, Su Y, Thu YM, Yu Y, Baugher P, Ellis DL, Sobolik-Delmaire T, Kelley M, Cheung TC, Ware CF, Richmond A (2008) J Biol Chem 283:15399-408 | 2008 |
| Allosteric modulation of kinases and GPCRs: design principles and structural diversity. Lewis JA, Lebois EP, Lindsley CW (2008) Curr Opin Chem Biol 12:269-80 | 2008 |
| Host nuclear factor-kappaB activation potentiates lung cancer metastasis. Stathopoulos GT, Sherrill TP, Han W, Sadikot RT, Yull FE, Blackwell TS, Fingleton B (2008) Mol Cancer Res 6:364-71 | 2008 |
| High-resolution high-speed panoramic cardiac imaging system. Evertson DW, Holcomb MR, Eames MC, Bray MA, Sidorov VY, Xu J, Wingard H, Dobrovolny HM, Woods MC, Gauthier DJ, Wikswo JP (2008) IEEE Trans Biomed Eng 55:1241-3 | 2008 |
| Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, Zent R (2008) Dev Biol 316:288-301 | 2008 |
| Banff 07 classification of renal allograft pathology: updates and future directions. Solez K, Colvin RB, Racusen LC, Haas M, Sis B, Mengel M, Halloran PF, Baldwin W, Banfi G, Collins AB, Cosio F, David DS, Drachenberg C, Einecke G, Fogo AB, Gibson IW, Glotz D, Iskandar SS, Kraus E, Lerut E, Mannon RB, Mihatsch M, Nankivell BJ, Nickeleit V, Papadimitriou JC, Randhawa P, Regele H, Renaudin K, Roberts I, Seron D, Smith RN, Valente M (2008) Am J Transplant 8:753-60 | 2008 |
| The PI3K/Akt pathway: recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors. Lindsley CW, Barnett SF, Layton ME, Bilodeau MT (2008) Curr Cancer Drug Targets 8:7-18 | 2008 |
| De novo high-resolution protein structure determination from sparse spin-labeling EPR data. Alexander N, Bortolus M, Al-Mestarihi A, Mchaourab H, Meiler J (2008) Structure 16:181-95 | 2008 |
| Integrative mathematical oncology. Anderson AR, Quaranta V (2008) Nat Rev Cancer 8:227-34 | 2008 |
| Synthesis, mechanical properties, biocompatibility, and biodegradation of polyurethane networks from lysine polyisocyanates. Guelcher SA, Srinivasan A, Dumas JE, Didier JE, McBride S, Hollinger JO (2008) Biomaterials 29:1762-75 | 2008 |
| Examining diabetic nephropathy through the lens of mouse genetics. Breyer MD, Tchekneva E, Qi Z, Takahashi T, Fogo AB, Harris RC (2007) Curr Diab Rep 7:459-66 | 2007 |
| CCR9 homes metastatic melanoma cells to the small bowel. Richmond A (2008) Clin Cancer Res 14:621-3 | 2008 |
| Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG (2008) J Am Soc Nephrol 19:677-84 | 2008 |
| A phased-array stimulator system for studying planar and curved cardiac activation wavefronts. Abbas RA, Lin SF, Mashburn D, Xu J, Wikswo JP (2008) IEEE Trans Biomed Eng 55:222-9 | 2008 |
| Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices. Georgescu W, Jourquin J, Estrada L, Anderson AR, Quaranta V, Wikswo JP (2008) Lab Chip 8:238-44 | 2008 |
| Mouse EP3 alpha, beta, and gamma receptor variants reduce tumor cell proliferation and tumorigenesis in vivo. Macias-Perez IM, Zent R, Carmosino M, Breyer MD, Breyer RM, Pozzi A (2008) J Biol Chem 283:12538-45 | 2008 |
| Molecule of the month. Overcoming resistance. Thomas AL, Lindsley CW (2008) Curr Top Med Chem 8:62 | 2008 |
| Application of combinatorial chemistry science on modern drug discovery. Kennedy JP, Williams L, Bridges TM, Daniels RN, Weaver D, Lindsley CW (2008) J Comb Chem 10:345-54 | 2008 |
| Mammalian collagen IV. Khoshnoodi J, Pedchenko V, Hudson BG (2008) Microsc Res Tech 71:357-70 | 2008 |
| NPXY motifs in the beta1 integrin cytoplasmic tail are required for functional reovirus entry. Maginnis MS, Mainou BA, Derdowski A, Johnson EM, Zent R, Dermody TS (2008) J Virol 82:3181-91 | 2008 |
| Dissection of the osteogenic effects of laminin-332 utilizing specific LG domains: LG3 induces osteogenic differentiation, but not mineralization. Klees RF, Salasznyk RM, Ward DF, Crone DE, Williams WA, Harris MP, Boskey A, Quaranta V, Plopper GE (2008) Exp Cell Res 314:763-73 | 2008 |
| Microfluidic switching system for analyzing chemotaxis responses of wortmannin-inhibited HL-60 cells. Liu Y, Sai J, Richmond A, Wikswo JP (2008) Biomed Microdevices 10:499-507 | 2008 |
| Bound to be different: neurotransmitter transporters meet their bacterial cousins. Henry LK, Meiler J, Blakely RD (2007) Mol Interv 7:306-9 | 2007 |
| Crosstalk between the alpha2beta1 integrin and c-met/HGF-R regulates innate immunity. McCall-Culbreath KD, Li Z, Zutter MM (2008) Blood 111:3562-70 | 2008 |
| Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism. Fang WB, Ireton RC, Zhuang G, Takahashi T, Reynolds A, Chen J (2008) J Cell Sci 121:358-68 | 2008 |
| Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists. Lewis LM, Sheffler D, Williams R, Bridges TM, Kennedy JP, Brogan JT, Mulder MJ, Williams L, Nalywajko NT, Niswender CM, Weaver CD, Conn PJ, Lindsley CW (2008) Bioorg Med Chem Lett 18:885-90 | 2008 |
| Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC, Moses HL (2008) Cancer Cell 13:23-35 | 2008 |
| Protozoan migration in bent microfluidic channels. Wang W, Shor LM, LeBoeuf EJ, Wikswo JP, Taghon GL, Kosson DS (2008) Appl Environ Microbiol 74:1945-9 | 2008 |
| Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: mechanism of action of pyridoxamine. Chetyrkin SV, Zhang W, Hudson BG, Serianni AS, Voziyan PA (2008) Biochemistry 47:997-1006 | 2008 |
| Generation and characterization of a novel phospho-specific monoclonal antibody to p120-catenin serine 879. Vaughan MH, Xia X, Wang X, Chronopoulou E, Gao GJ, Campos-Gonzalez R, Reynolds AB (2007) Hybridoma (Larchmt) 26:407-15 | 2007 |
| Insight into the genetics of diabetic nephropathy through the study of mice. Breyer MD, Qi Z, Tchekneva EE, Harris RC (2008) Curr Opin Nephrol Hypertens 17:82-6 | 2008 |
| An update on cyclooxygenase-2 expression and metabolites in the kidney. Harris RC (2008) Curr Opin Nephrol Hypertens 17:64-9 | 2008 |
| The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. Brantley-Sieders DM, Zhuang G, Hicks D, Fang WB, Hwang Y, Cates JM, Coffman K, Jackson D, Bruckheimer E, Muraoka-Cook RS, Chen J (2008) J Clin Invest 118:64-78 | 2008 |
| The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Tager AM, LaCamera P, Shea BS, Campanella GS, Selman M, Zhao Z, Polosukhin V, Wain J, Karimi-Shah BA, Kim ND, Hart WK, Pardo A, Blackwell TS, Xu Y, Chun J, Luster AD (2008) Nat Med 14:45-54 | 2008 |
| Domain architecture and biochemical characterization of vertebrate Mcm10. Robertson PD, Warren EM, Zhang H, Friedman DB, Lary JW, Cole JL, Tutter AV, Walter JC, Fanning E, Eichman BF (2008) J Biol Chem 283:3338-48 | 2008 |
| Renal localization and regulation of 15-hydroxyprostaglandin dehydrogenase. Yao B, Xu J, Harris RC, Zhang MZ (2008) Am J Physiol Renal Physiol 294:F433-9 | 2008 |
| alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner. Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM (2008) Blood 111:1980-8 | 2008 |
| Disease-specific gene expression profiling in multiple models of lung disease. Lewis CC, Yang JY, Huang X, Banerjee SK, Blackburn MR, Baluk P, McDonald DM, Blackwell TS, Nagabhushanam V, Peters W, Voehringer D, Erle DJ (2008) Am J Respir Crit Care Med 177:376-87 | 2008 |
| Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis. Stathopoulos GT, Sherrill TP, Han W, Sadikot RT, Polosukhin VV, Fingleton B, Yull FE, Blackwell TS (2008) Clin Exp Metastasis 25:43-51 | 2008 |
| Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis. Stathopoulos GT, Sherrill TP, Cheng DS, Scoggins RM, Han W, Polosukhin VV, Connelly L, Yull FE, Fingleton B, Blackwell TS (2007) Proc Natl Acad Sci U S A 104:18514-9 | 2007 |
| Structural models for the KCNQ1 voltage-gated potassium channel. Smith JA, Vanoye CG, George AL, Meiler J, Sanders CR (2007) Biochemistry 46:14141-52 | 2007 |
| Human deafness mutation E385D disrupts the mechanochemical coupling and subcellular targeting of myosin-1a. Yengo CM, Ananthanarayanan SK, Brosey CA, Mao S, Tyska MJ (2008) Biophys J 94:L5-7 | 2008 |
| A high-voltage cardiac stimulator for field shocks of a whole heart in a bath. Mashburn DN, Hinkson SJ, Woods MC, Gilligan JM, Holcomb MR, Wikswo JP (2007) Rev Sci Instrum 78:104302 | 2007 |
| 15(S)-HETE production in human retinal microvascular endothelial cells by hypoxia: Novel role for MEK1 in 15(S)-HETE induced angiogenesis. Bajpai AK, Blaskova E, Pakala SB, Zhao T, Glasgow WC, Penn JS, Johnson DA, Rao GN (2007) Invest Ophthalmol Vis Sci 48:4930-8 | 2007 |
| Acute renal failure and myalgia in a transplant patient. Najafian B, Franklin DB, Fogo AB (2007) J Am Soc Nephrol 18:2870-4 | 2007 |
| Tumor necrosis factor-alpha promotes malignant pleural effusion. Stathopoulos GT, Kollintza A, Moschos C, Psallidas I, Sherrill TP, Pitsinos EN, Vassiliou S, Karatza M, Papiris SA, Graf D, Orphanidou D, Light RW, Roussos C, Blackwell TS, Kalomenidis I (2007) Cancer Res 67:9825-34 | 2007 |
| Opposing roles of murine duffy antigen receptor for chemokine and murine CXC chemokine receptor-2 receptors in murine melanoma tumor growth. Horton LW, Yu Y, Zaja-Milatovic S, Strieter RM, Richmond A (2007) Cancer Res 67:9791-9 | 2007 |
| Modeling of effects of nutrient gradients on cell proliferation in microfluidic bioreactor. Hu G, Quaranta V, Li D (2007) Biotechnol Prog 23:1347-54 | 2007 |
| A perspective on arterionephrosclerosis: from pathology to potential pathogenesis. Marcantoni C, Fogo AB (2007) J Nephrol 20:518-24 | 2007 |
| High-resolution manganese-enhanced MRI of experimental retinopathy of prematurity. Berkowitz BA, Roberts R, Penn JS, Gradianu M (2007) Invest Ophthalmol Vis Sci 48:4733-40 | 2007 |
| Puromycin induces reversible proteinuric injury in transgenic mice expressing cyclooxygenase-2 in podocytes. Jo YI, Cheng H, Wang S, Moeckel GW, Harris RC (2007) Nephron Exp Nephrol 107:e87-94 | 2007 |
| Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site. McKinney BA, Kallewaard NL, Crowe JE, Meiler J (2007) Immunome Res 3:8 | 2007 |
| Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance. Singh AB, Sugimoto K, Dhawan P, Harris RC (2007) Am J Physiol Cell Physiol 293:C1660-8 | 2007 |
| Juxtacrine activation of epidermal growth factor (EGF) receptor by membrane-anchored heparin-binding EGF-like growth factor protects epithelial cells from anoikis while maintaining an epithelial phenotype. Singh AB, Sugimoto K, Harris RC (2007) J Biol Chem 282:32890-901 | 2007 |
| Modulation of glomerulosclerosis. Ma LJ, Fogo AB (2007) Semin Immunopathol 29:385-95 | 2007 |
| ErbB4 isoforms selectively regulate growth factor induced Madin-Darby canine kidney cell tubulogenesis. Zeng F, Zhang MZ, Singh AB, Zent R, Harris RC (2007) Mol Biol Cell 18:4446-56 | 2007 |
| The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane. Fukumoto Y, Shintani Y, Reynolds AB, Johnson KR, Wheelock MJ (2008) Exp Cell Res 314:52-67 | 2008 |
| Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice. Zhang H, Lawson WE, Polosukhin VV, Pozzi A, Blackwell TS, Litingtung Y, Chiang C (2007) Am J Pathol 171:1113-26 | 2007 |
| Characterization of a putative intrarenal serotonergic system. Xu J, Yao B, Fan X, Langworthy MM, Zhang MZ, Harris RC (2007) Am J Physiol Renal Physiol 293:F1468-75 | 2007 |
| Update on cyclooxygenase-2 inhibitors. Harris RC, Breyer MD (2006) Clin J Am Soc Nephrol 1:236-45 | 2006 |
| Recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors. Lindsley CW, Barnett SF, Yaroschak M, Bilodeau MT, Layton ME (2007) Curr Top Med Chem 7:1349-63 | 2007 |
| Induction and function of lipocalin prostaglandin D synthase in host immunity. Joo M, Kwon M, Sadikot RT, Kingsley PJ, Marnett LJ, Blackwell TS, Peebles RS, Urade Y, Christman JW (2007) J Immunol 179:2565-75 | 2007 |
| Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia. Polosukhin VV, Lawson WE, Milstone AP, Egunova SM, Kulipanov AG, Tchuvakin SG, Massion PP, Blackwell TS (2007) Virchows Arch 451:793-803 | 2007 |
| Conditional regulation of cyclooxygenase-2 in tracheobronchial epithelial cells modulates pulmonary immunity. Park GY, Hu N, Wang X, Sadikot RT, Yull FE, Joo M, Peebles RS, Blackwell TS, Christman JW (2007) Clin Exp Immunol 150:245-54 | 2007 |
| Effects of podocyte injury on glomerular development. Ma J, Rossini M, Yang HC, Zuo Y, Fogo AB, Ichikawa I (2007) Pediatr Res 62:417-21 | 2007 |
| Synthesis, in vitro degradation, and mechanical properties of two-component poly(ester urethane)urea scaffolds: effects of water and polyol composition. Guelcher S, Srinivasan A, Hafeman A, Gallagher K, Doctor J, Khetan S, McBride S, Hollinger J (2007) Tissue Eng 13:2321-33 | 2007 |
| Signaling pathways regulating TC21-induced tumorigenesis. Erdogan M, Pozzi A, Bhowmick N, Moses HL, Zent R (2007) J Biol Chem 282:27713-20 | 2007 |
| Mechanisms of progression of chronic kidney disease. Fogo AB (2007) Pediatr Nephrol 22:2011-22 | 2007 |
| Expression of activated Akt in benign nevi, Spitz nevi and melanomas. Kantrow SM, Boyd AS, Ellis DL, Nanney LB, Richmond A, Shyr Y, Robbins JB (2007) J Cutan Pathol 34:593-6 | 2007 |
| Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques. Suganuma E, Babaev VR, Motojima M, Zuo Y, Ayabe N, Fogo AB, Ichikawa I, Linton MF, Fazio S, Kon V (2007) J Am Soc Nephrol 18:2311-9 | 2007 |
| Role of chemokines in tumor growth. Raman D, Baugher PJ, Thu YM, Richmond A (2007) Cancer Lett 256:137-65 | 2007 |
| Hypoxia enhances CXCR4 expression in human microvascular endothelial cells and human melanoma cells. Schutyser E, Su Y, Yu Y, Gouwy M, Zaja-Milatovic S, Van Damme J, Richmond A (2007) Eur Cytokine Netw 18:59-70 | 2007 |
| A new, non-SSRI mechanism of action for Prozac. Daniels RN, Lindsley CW (2007) Curr Top Med Chem 7:1039 | 2007 |
| The MD/PhD pathway to a career in laboratory medicine. Santoro SA, Mosse CA, Young PP (2007) Clin Lab Med 27:425-34; abstract ix | 2007 |
| Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice. Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC (2007) Am J Physiol Lung Cell Mol Physiol 293:L491-6 | 2007 |
| The alpha2beta1 integrin: a novel collectin/C1q receptor. Zutter MM, Edelson BT (2007) Immunobiology 212:343-53 | 2007 |
| Myosin-1a powers the sliding of apical membrane along microvillar actin bundles. McConnell RE, Tyska MJ (2007) J Cell Biol 177:671-81 | 2007 |
| CCAAT displacement protein regulates nuclear factor-kappa beta-mediated chemokine transcription in melanoma cells. Ueda Y, Su Y, Richmond A (2007) Melanoma Res 17:91-103 | 2007 |
| Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway. Cheng DS, Han W, Chen SM, Sherrill TP, Chont M, Park GY, Sheller JR, Polosukhin VV, Christman JW, Yull FE, Blackwell TS (2007) J Immunol 178:6504-13 | 2007 |
| The homeodomain transcription factors Cdx1 and Cdx2 induce E-cadherin adhesion activity by reducing beta- and p120-catenin tyrosine phosphorylation. Ezaki T, Guo RJ, Li H, Reynolds AB, Lynch JP (2007) Am J Physiol Gastrointest Liver Physiol 293:G54-65 | 2007 |
| PPAR-gamma agonist protects podocytes from injury. Kanjanabuch T, Ma LJ, Chen J, Pozzi A, Guan Y, Mundel P, Fogo AB (2007) Kidney Int 71:1232-9 | 2007 |
| Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice. Kanetsuna Y, Takahashi K, Nagata M, Gannon MA, Breyer MD, Harris RC, Takahashi T (2007) Am J Pathol 170:1473-84 | 2007 |
| Emerging from the shadow of Vioxx. Lindsley CW (2007) Curr Top Med Chem 7:739 | 2007 |
| Functional characterization of chimpanzee cytomegalovirus chemokine, vCXCL-1(CCMV). Miller-Kittrell M, Sai J, Penfold M, Richmond A, Sparer TE (2007) Virology 364:454-65 | 2007 |
| Modulation of angiotensin II and norepinephrine-induced plasminogen activator inhibitor-1 expression by AT1a receptor deficiency. Brown NJ, Bradford J, Wang Z, Lea W, Ma L, Ma J, Vaughan DE, Fogo AB (2007) Kidney Int 72:72-81 | 2007 |
| Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. Fox MA, Sanes JR, Borza DB, Eswarakumar VP, Fässler R, Hudson BG, John SW, Ninomiya Y, Pedchenko V, Pfaff SL, Rheault MN, Sado Y, Segal Y, Werle MJ, Umemori H (2007) Cell 129:179-93 | 2007 |
| Genetics of diabetic nephropathy: lessons from mice. Breyer MD, Tchekneva E, Qi Z, Takahashi T, Fogo AB, Zhao HJ, Harris RC (2007) Semin Nephrol 27:237-47 | 2007 |
| Angiogenesis in diabetic nephropathy. Zent R, Pozzi A (2007) Semin Nephrol 27:161-71 | 2007 |
| Synthesis and characterization of segmented poly(esterurethane urea) elastomers for bone tissue engineering. Kavlock KD, Pechar TW, Hollinger JO, Guelcher SA, Goldstein AS (2007) Acta Biomater 3:475-84 | 2007 |
| DNA damage recognition and repair by 3-methyladenine DNA glycosylase I (TAG). Metz AH, Hollis T, Eichman BF (2007) EMBO J 26:2411-20 | 2007 |
| Systemic targeting inhibitor of kappaB kinase inhibits melanoma tumor growth. Yang J, Pan WH, Clawson GA, Richmond A (2007) Cancer Res 67:3127-34 | 2007 |
| RhoB plays an essential role in CXCR2 sorting decisions. Neel NF, Lapierre LA, Goldenring JR, Richmond A (2007) J Cell Sci 120:1559-71 | 2007 |
| Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo. Rao R, Redha R, Macias-Perez I, Su Y, Hao C, Zent R, Breyer MD, Pozzi A (2007) J Biol Chem 282:16959-68 | 2007 |
| Antioxidants tiron and N-acetyl-L-cysteine differentially mediate apoptosis in melanoma cells via a reactive oxygen species-independent NF-kappaB pathway. Yang J, Su Y, Richmond A (2007) Free Radic Biol Med 42:1369-80 | 2007 |
| Chronic myeloid leukemia-associated membranoproliferative glomerulonephritis that responded to imatinib mesylate therapy. Dwyer JP, Yates KM, Sumner EL, Stone WJ, Wang Y, Koury MJ, Fogo AB, Zent R (2007) Clin Nephrol 67:176-81 | 2007 |
| Kidney development and gene expression in the HIF2alpha knockout mouse. Steenhard BM, Freeburg PB, Isom K, Stroganova L, Borza DB, Hudson BG, St John PL, Zelenchuk A, Abrahamson DR (2007) Dev Dyn 236:1115-25 | 2007 |
| Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation. Chen X, Abair TD, Ibanez MR, Su Y, Frey MR, Dise RS, Polk DB, Singh AB, Harris RC, Zent R, Pozzi A (2007) Mol Cell Biol 27:3313-26 | 2007 |
| Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2. Sadikot RT, Zeng H, Azim AC, Joo M, Dey SK, Breyer RM, Peebles RS, Blackwell TS, Christman JW (2007) Eur J Immunol 37:1001-9 | 2007 |
| PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis. Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE (2007) Mol Pharmacol 71:1399-406 | 2007 |
| The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain. Kang JS, Kashtan CE, Turner AN, Heidet L, Hudson BG, Borza DB (2007) J Biol Chem 282:10670-7 | 2007 |
| Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite. Chen J, Chen JK, Falck JR, Guthi JS, Anjaiah S, Capdevila JH, Harris RC (2007) Mol Cell Biol 27:3023-34 | 2007 |
| Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution. Reese M, Sánchez-Pedregal VM, Kubicek K, Meiler J, Blommers MJ, Griesinger C, Carlomagno T (2007) Angew Chem Int Ed Engl 46:1864-8 | 2007 |
| Signals from both sides: Control of cardiac development by the endocardium and epicardium. Smith TK, Bader DM (2007) Semin Cell Dev Biol 18:84-9 | 2007 |
| A transgenic model reveals important roles for the NF-kappa B alternative pathway (p100/p52) in mammary development and links to tumorigenesis. Connelly L, Robinson-Benion C, Chont M, Saint-Jean L, Li H, Polosukhin VV, Blackwell TS, Yull FE (2007) J Biol Chem 282:10028-35 | 2007 |
| Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR. Barnett JM, McCollum GW, Fowler JA, Duan JJ, Kay JD, Liu RQ, Bingaman DP, Penn JS (2007) Invest Ophthalmol Vis Sci 48:907-15 | 2007 |
| Preclinical drug discovery research and training at Vanderbilt. Lindsley CW, Weaver D, Jones C, Marnett L, Conn PJ (2007) ACS Chem Biol 2:17-20 | 2007 |
| Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages. Joo M, Wright JG, Hu NN, Sadikot RT, Park GY, Blackwell TS, Christman JW (2007) Am J Physiol Lung Cell Mol Physiol 292:L1219-26 | 2007 |
| Identification of N-linked glycosylation sites in human nephrin using mass spectrometry. Khoshnoodi J, Hill S, Tryggvason K, Hudson B, Friedman DB (2007) J Mass Spectrom 42:370-9 | 2007 |
| Overexpression of cyclooxygenase-2 predisposes to podocyte injury. Cheng H, Wang S, Jo YI, Hao CM, Zhang M, Fan X, Kennedy C, Breyer MD, Moeckel GW, Harris RC (2007) J Am Soc Nephrol 18:551-9 | 2007 |
| Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells. Zhou W, Hashimoto K, Goleniewska K, O'Neal JF, Ji S, Blackwell TS, Fitzgerald GA, Egan KM, Geraci MW, Peebles RS (2007) J Immunol 178:702-10 | 2007 |
| Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse. Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, Shield CF, Sheppard D, Gardner HA, Violette SM (2007) Am J Pathol 170:110-25 | 2007 |
| Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity. Davies SS, Brantley EJ, Voziyan PA, Amarnath V, Zagol-Ikapitte I, Boutaud O, Hudson BG, Oates JA, Roberts LJ (2006) Biochemistry 45:15756-67 | 2006 |
| p120-catenin: Past and present. Reynolds AB (2007) Biochim Biophys Acta 1773:2-7 | 2007 |
| A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy. Tchekneva EE, Rinchik EM, Polosukhina D, Davis LS, Kadkina V, Mohamed Y, Dunn SR, Sharma K, Qi Z, Fogo AB, Breyer MD (2007) J Am Soc Nephrol 18:103-12 | 2007 |
| Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells. Zhou W, Blackwell TS, Goleniewska K, O'Neal JF, Fitzgerald GA, Lucitt M, Breyer RM, Peebles RS (2007) J Leukoc Biol 81:809-17 | 2007 |
| Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation. Zhuang G, Hunter S, Hwang Y, Chen J (2007) J Biol Chem 282:2683-94 | 2007 |
| New algorithms and an in silico benchmark for computational enzyme design. Zanghellini A, Jiang L, Wollacott AM, Cheng G, Meiler J, Althoff EA, Röthlisberger D, Baker D (2006) Protein Sci 15:2785-94 | 2006 |
| p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB (2006) Cell 127:1027-39 | 2006 |
| Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Anderson AR, Weaver AM, Cummings PT, Quaranta V (2006) Cell 127:905-15 | 2006 |
| The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation. Lee JS, Wurfel MM, Matute-Bello G, Frevert CW, Rosengart MR, Ranganathan M, Wong VW, Holden T, Sutlief S, Richmond A, Peiper S, Martin TR (2006) J Immunol 177:8086-94 | 2006 |
| Molecular recognition in the assembly of collagens: terminal noncollagenous domains are key recognition modules in the formation of triple helical protomers. Khoshnoodi J, Cartailler JP, Alvares K, Veis A, Hudson BG (2006) J Biol Chem 281:38117-21 | 2006 |
| Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice. Brantley-Sieders DM, Fang WB, Hwang Y, Hicks D, Chen J (2006) Cancer Res 66:10315-24 | 2006 |
| Wound healing in the alpha2beta1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression. Grenache DG, Zhang Z, Wells LE, Santoro SA, Davidson JM, Zutter MM (2007) J Invest Dermatol 127:455-66 | 2007 |
| Specific involvement of SRC family kinase activation in the pathogenesis of retinal neovascularization. Werdich XQ, Penn JS (2006) Invest Ophthalmol Vis Sci 47:5047-56 | 2006 |
| Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC (2006) Diabetes 55:2974-85 | 2006 |
| Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT(1) and AT(2) receptors. Zhang MZ, Yao B, Cheng HF, Wang SW, Inagami T, Harris RC (2006) Proc Natl Acad Sci U S A 103:16045-50 | 2006 |
| The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide. Sánchez-Pedregal VM, Kubicek K, Meiler J, Lyothier I, Paterson I, Carlomagno T (2006) Angew Chem Int Ed Engl 45:7388-94 | 2006 |
| Plasminogen activator inhibitor-1 in chronic kidney disease: evidence and mechanisms of action. Eddy AA, Fogo AB (2006) J Am Soc Nephrol 17:2999-3012 | 2006 |
| Involvement of p120 catenin in myopodial assembly and nerve-muscle synapse formation. Madhavan R, Zhao XT, Reynolds AB, Peng HB (2006) J Neurobiol 66:1511-27 | 2006 |
| A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis. Chen L, Hellmark T, Pedchenko V, Hudson BG, Pusey CD, Fox JW, Bolton WK (2006) J Am Soc Nephrol 17:3076-81 | 2006 |
| Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis. Gray KD, Simovic MO, Blackwell TS, Christman JW, May AK, Parman KS, Chapman WC, Stain SC (2006) Pancreas 33:260-7 | 2006 |
| The IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells. Sai J, Walker G, Wikswo J, Richmond A (2006) J Biol Chem 281:35931-41 | 2006 |
| HIV-1 genes vpr and nef synergistically damage podocytes, leading to glomerulosclerosis. Zuo Y, Matsusaka T, Zhong J, Ma J, Ma LJ, Hanna Z, Jolicoeur P, Fogo AB, Ichikawa I (2006) J Am Soc Nephrol 17:2832-43 | 2006 |
| ROSETTALIGAND: protein-small molecule docking with full side-chain flexibility. Meiler J, Baker D (2006) Proteins 65:538-48 | 2006 |
| Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. Zhao HJ, Wang S, Cheng H, Zhang MZ, Takahashi T, Fogo AB, Breyer MD, Harris RC (2006) J Am Soc Nephrol 17:2664-9 | 2006 |
| p120 serine and threonine phosphorylation is controlled by multiple ligand-receptor pathways but not cadherin ligation. Xia X, Carnahan RH, Vaughan MH, Wildenberg GA, Reynolds AB (2006) Exp Cell Res 312:3336-48 | 2006 |
| Can glomerulosclerosis be reversed? Fogo AB (2006) Nat Clin Pract Nephrol 2:290-1 | 2006 |
| Potential side effects of renin inhibitors--mechanisms based on comparison with other renin-angiotensin blockers. Cheng H, Harris RC (2006) Expert Opin Drug Saf 5:631-41 | 2006 |
| Myosin at work: motor adaptations for a variety of cellular functions. O'Connell CB, Tyska MJ, Mooseker MS (2007) Biochim Biophys Acta 1773:615-30 | 2007 |
| Specific deletion of CMF1 nuclear localization domain causes incomplete cell cycle withdrawal and impaired differentiation in avian skeletal myoblasts. Dees E, Robertson JB, Zhu T, Bader D (2006) Exp Cell Res 312:3000-14 | 2006 |
| The clot thickens. Fogo AB (2006) Kidney Int 70:620-1 | 2006 |
| Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice. Miyoshi T, Hirohata S, Ogawa H, Doi M, Obika M, Yonezawa T, Sado Y, Kusachi S, Kyo S, Kondo S, Shiratori Y, Hudson BG, Ninomiya Y (2006) FASEB J 20:1904-6 | 2006 |
| Slow decline in allograft function in a renal transplant patient. Schaefer HM, Helderman JH, Fogo AB (2006) Am J Kidney Dis 48:335-8 | 2006 |
| Vascular endothelial growth factor levels in post-CABG pleural effusions are associated with pleural inflammation and permeability. Kalomenidis I, Stathopoulos GT, Barnette R, Papiris S, Blackwell TS, Roussos C, Light RW (2007) Respir Med 101:223-9 | 2007 |
| Differential regulation of CXC ligand 1 transcription in melanoma cell lines by poly(ADP-ribose) polymerase-1. Amiri KI, Ha HC, Smulson ME, Richmond A (2006) Oncogene 25:7714-22 | 2006 |
| Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth. Liang XB, Ma LJ, Naito T, Wang Y, Madaio M, Zent R, Pozzi A, Fogo AB (2006) J Am Soc Nephrol 17:1886-95 | 2006 |
| COX-2 and the kidney. Harris RC (2006) J Cardiovasc Pharmacol 47 Suppl 1:S37-42 | 2006 |
| Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. Hunter SG, Zhuang G, Brantley-Sieders D, Swat W, Cowan CW, Chen J (2006) Mol Cell Biol 26:4830-42 | 2006 |
| Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A (2006) Kidney Int 70:460-70 | 2006 |
| Synthesis and in vitro biocompatibility of injectable polyurethane foam scaffolds. Guelcher SA, Patel V, Gallagher KM, Connolly S, Didier JE, Doctor JS, Hollinger JO (2006) Tissue Eng 12:1247-59 | 2006 |
| Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells. Ueda Y, Neel NF, Schutyser E, Raman D, Richmond A (2006) Cancer Res 66:5665-75 | 2006 |
| Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, Grant MB, Hansen R, Hauswirth WW, Hardy RJ, Hinton DR, Hughes S, McLeod DS, Palmer EA, Patz A, Penn JS, Raisler BJ, Repka MX, Saint-Geniez M, Shaw LC, Shima DT, Smith BT, Smith LE, Tahija SG, Tasman W, Trese MT (2006) Mol Vis 12:532-80 | 2006 |
| Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3. Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R (2006) J Biol Chem 281:20932-9 | 2006 |
| Membranous glomerulopathy with spherules: an uncommon variant with obscure pathogenesis. Kowalewska J, Smith KD, Hudkins KL, Chang A, Fogo AB, Houghton D, Leslie D, Aitchison J, Nicosia RF, Alpers CE (2006) Am J Kidney Dis 47:983-92 | 2006 |
| Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes. Kanetsuna Y, Hirano K, Nagata M, Gannon MA, Takahashi K, Harris RC, Breyer MD, Takahashi T (2006) Am J Physiol Renal Physiol 291:F1315-22 | 2006 |
| Synthesis of biocompatible segmented polyurethanes from aliphatic diisocyanates and diurea diol chain extenders. Guelcher SA, Gallagher KM, Didier JE, Klinedinst DB, Doctor JS, Goldstein AS, Wilkes GL, Beckman EJ, Hollinger JO (2005) Acta Biomater 1:471-84 | 2005 |
| Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. Nakagawa K, Holla VR, Wei Y, Wang WH, Gatica A, Wei S, Mei S, Miller CM, Cha DR, Price E, Zent R, Pozzi A, Breyer MD, Guan Y, Falck JR, Waterman MR, Capdevila JH (2006) J Clin Invest 116:1696-702 | 2006 |
| Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase. Chen JX, Zeng H, Lawrence ML, Blackwell TS, Meyrick B (2006) Am J Physiol Heart Circ Physiol 291:H1563-72 | 2006 |
| NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha. Park GY, Wang X, Hu N, Pedchenko TV, Blackwell TS, Christman JW (2006) J Biol Chem 281:18684-90 | 2006 |
| CytLEK1 is a regulator of plasma membrane recycling through its interaction with SNAP-25. Pooley RD, Reddy S, Soukoulis V, Roland JT, Goldenring JR, Bader DM (2006) Mol Biol Cell 17:3176-86 | 2006 |
| Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. Kramerov AA, Saghizadeh M, Pan H, Kabosova A, Montenarh M, Ahmed K, Penn JS, Chan CK, Hinton DR, Grant MB, Ljubimov AV (2006) Am J Pathol 168:1722-36 | 2006 |
| Sequential expression of type IV collagen networks: testis as a model and relevance to spermatogenesis. Harvey SJ, Perry J, Zheng K, Chen D, Sado Y, Jefferson B, Ninomiya Y, Jacobs R, Hudson BG, Thorner PS (2006) Am J Pathol 168:1587-97 | 2006 |
| Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy. Chen J, Chen JK, Neilson EG, Harris RC (2006) J Am Soc Nephrol 17:1615-23 | 2006 |
| Diabetic nephropathy. Giannico G, Miller FJ, Fogo AB (2006) Am J Kidney Dis 47:A42, e61-3 | 2006 |
| Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis. Yang HC, Ma LJ, Ma J, Fogo AB (2006) Kidney Int 69:1756-64 | 2006 |
| Role of renal cortical cyclooxygenase-2 expression in hyperfiltration in rats with high-protein intake. Yao B, Xu J, Qi Z, Harris RC, Zhang MZ (2006) Am J Physiol Renal Physiol 291:F368-74 | 2006 |
| Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury. Everhart MB, Han W, Sherrill TP, Arutiunov M, Polosukhin VV, Burke JR, Sadikot RT, Christman JW, Yull FE, Blackwell TS (2006) J Immunol 176:4995-5005 | 2006 |
| Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. Sadikot RT, Zeng H, Joo M, Everhart MB, Sherrill TP, Li B, Cheng DS, Yull FE, Christman JW, Blackwell TS (2006) J Immunol 176:4923-30 | 2006 |
| CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. Wang D, Wang H, Brown J, Daikoku T, Ning W, Shi Q, Richmond A, Strieter R, Dey SK, DuBois RN (2006) J Exp Med 203:941-51 | 2006 |
| Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation. Maus UA, Janzen S, Wall G, Srivastava M, Blackwell TS, Christman JW, Seeger W, Welte T, Lohmeyer J (2006) Am J Respir Cell Mol Biol 35:227-35 | 2006 |
| Characterization of Bves expression during mouse development using newly generated immunoreagents. Smith TK, Bader DM (2006) Dev Dyn 235:1701-8 | 2006 |
| Conformational diversity of the Goodpasture antigen, the noncollagenous-1 domain of the alpha3 chain of collagen IV. Calvete JJ, Revert F, Blanco M, Cervera J, Tárrega C, Sanz L, Revert-Ros F, Granero F, Pérez-Payá E, Hudson BG, Saus J (2006) Proteomics 6 Suppl 1:S237-44 | 2006 |
| Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury. Ma J, Weisberg A, Griffin JP, Vaughan DE, Fogo AB, Brown NJ (2006) Kidney Int 69:1064-72 | 2006 |
| NF-kappaB activation in melanoma. Ueda Y, Richmond A (2006) Pigment Cell Res 19:112-24 | 2006 |
| A thorough dynamic interpretation of residual dipolar couplings in ubiquitin. Lakomek NA, Carlomagno T, Becker S, Griesinger C, Meiler J (2006) J Biomol NMR 34:101-15 | 2006 |
| Beta1 integrin mediates internalization of mammalian reovirus. Maginnis MS, Forrest JC, Kopecky-Bromberg SA, Dickeson SK, Santoro SA, Zutter MM, Nemerow GR, Bergelson JM, Dermody TS (2006) J Virol 80:2760-70 | 2006 |
| p120-catenin mediates inflammatory responses in the skin. Perez-Moreno M, Davis MA, Wong E, Pasolli HA, Reynolds AB, Fuchs E (2006) Cell 124:631-44 | 2006 |
| H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis. Pozzi A, Coffa S, Bulus N, Zhu W, Chen D, Chen X, Mernaugh G, Su Y, Cai S, Singh A, Brissova M, Zent R (2006) Mol Biol Cell 17:2046-56 | 2006 |
| BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways. Yang J, Amiri KI, Burke JR, Schmid JA, Richmond A (2006) Clin Cancer Res 12:950-60 | 2006 |
| Bves, a member of the Popeye domain-containing gene family. Osler ME, Smith TK, Bader DM (2006) Dev Dyn 235:586-93 | 2006 |
| Hyperoxia and apoptosis in developing mouse lung mesenchyme. Dieperink HI, Blackwell TS, Prince LS (2006) Pediatr Res 59:185-90 | 2006 |
| Antiangiogenic therapy in diabetic nephropathy. Zent R, Pozzi A (2006) J Am Soc Nephrol 17:325-7 | 2006 |
| Toward a unified theory of renal progression. Harris RC, Neilson EG (2006) Annu Rev Med 57:365-80 | 2006 |
| Xbves is a regulator of epithelial movement during early Xenopus laevis development. Ripley AN, Osler ME, Wright CV, Bader D (2006) Proc Natl Acad Sci U S A 103:614-9 | 2006 |
| Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events. Werdich XQ, Penn JS (2005) Angiogenesis 8:315-26 | 2005 |
| Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Davis MA, Reynolds AB (2006) Dev Cell 10:21-31 | 2006 |
| Angiostatic effect of penetrating ocular injury: role of pigment epithelium-derived factor. Penn JS, McCollum GW, Barnett JM, Werdich XQ, Koepke KA, Rajaratnam VS (2006) Invest Ophthalmol Vis Sci 47:405-14 | 2006 |
| Nitric oxide stimulates cyclooxygenase-2 in cultured cTAL cells through a p38-dependent pathway. Cheng HF, Zhang MZ, Harris RC (2006) Am J Physiol Renal Physiol 290:F1391-7 | 2006 |
| Mechanism of chain selection in the assembly of collagen IV: a prominent role for the alpha2 chain. Khoshnoodi J, Sigmundsson K, Cartailler JP, Bondar O, Sundaramoorthy M, Hudson BG (2006) J Biol Chem 281:6058-69 | 2006 |
| Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction. Suganuma E, Zuo Y, Ayabe N, Ma J, Babaev VR, Linton MF, Fazio S, Ichikawa I, Fogo AB, Kon V (2006) J Am Soc Nephrol 17:433-41 | 2006 |
| Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. Stafforini DM, Sheller JR, Blackwell TS, Sapirstein A, Yull FE, McIntyre TM, Bonventre JV, Prescott SM, Roberts LJ (2006) J Biol Chem 281:4616-23 | 2006 |
| Inhibition of retinal neovascularization by soluble EphA2 receptor. Chen J, Hicks D, Brantley-Sieders D, Cheng N, McCollum GW, Qi-Werdich X, Penn J (2006) Exp Eye Res 82:664-73 | 2006 |
| Bioluminescence imaging. Sadikot RT, Blackwell TS (2005) Proc Am Thorac Soc 2:537-40, 511-2 | 2005 |
| Immunolocalization of fibroblast growth factor-1 (FGF-1), its receptor (FGFR-1), and fibroblast-specific protein-1 (FSP-1) in inflammatory renal disease. Rossini M, Cheunsuchon B, Donnert E, Ma LJ, Thomas JW, Neilson EG, Fogo AB (2005) Kidney Int 68:2621-8 | 2005 |
| Progression versus regression of chronic kidney disease. Fogo AB (2006) Nephrol Dial Transplant 21:281-4 | 2006 |
| Pyridoxamine lowers oxalate excretion and kidney crystals in experimental hyperoxaluria: a potential therapy for primary hyperoxaluria. Scheinman JI, Voziyan PA, Belmont JM, Chetyrkin SV, Kim D, Hudson BG (2005) Urol Res 33:368-71 | 2005 |
| The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature. Wilm B, Ipenberg A, Hastie ND, Burch JB, Bader DM (2005) Development 132:5317-28 | 2005 |
| Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin. Lakomek NA, Farès C, Becker S, Carlomagno T, Meiler J, Griesinger C (2005) Angew Chem Int Ed Engl 44:7776-8 | 2005 |
| Chronic renal failure and abnormal tubular cells in 2 siblings. Rossini M, Coventry S, Duff DR, Fogo AB (2005) Am J Kidney Dis 46:982-7 | 2005 |
| Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. Lawson WE, Polosukhin VV, Stathopoulos GT, Zoia O, Han W, Lane KB, Li B, Donnelly EF, Holburn GE, Lewis KG, Collins RD, Hull WM, Glasser SW, Whitsett JA, Blackwell TS (2005) Am J Pathol 167:1267-77 | 2005 |
| Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen. Wang XP, Fogo AB, Colon S, Giannico G, Abul-Ezz SR, Miner JH, Borza DB (2005) J Am Soc Nephrol 16:3563-71 | 2005 |
| Chronic allograft nephropathy: expression and localization of PAI-1 and PPAR-gamma. Revelo MP, Federspiel C, Helderman H, Fogo AB (2005) Nephrol Dial Transplant 20:2812-9 | 2005 |
| Regulation of collagen type IV genes is organ-specific: evidence from a canine model of Alport syndrome. Zheng K, Perry J, Harvey SJ, Sado Y, Ninomiya Y, Jefferson B, Jacobs R, Hudson BG, Thorner PS (2005) Kidney Int 68:2121-30 | 2005 |
| Production and characterization of mouse ureteric bud cell-specific rat hybridoma antibodies utilizing subtractive immunization and high-throughput screening. Mernaugh RL, Yan H, Chen D, Edl J, Hanley G, Pozzi A, Zent R (2005) J Immunol Methods 306:115-27 | 2005 |
| Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion. Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS (2006) Am J Respir Cell Mol Biol 34:142-50 | 2006 |
| Altered CXCR2 signaling in beta-arrestin-2-deficient mouse models. Su Y, Raghuwanshi SK, Yu Y, Nanney LB, Richardson RM, Richmond A (2005) J Immunol 175:5396-402 | 2005 |
| Regression of existing glomerulosclerosis by inhibition of aldosterone. Aldigier JC, Kanjanbuch T, Ma LJ, Brown NJ, Fogo AB (2005) J Am Soc Nephrol 16:3306-14 | 2005 |
| Bves modulates epithelial integrity through an interaction at the tight junction. Osler ME, Chang MS, Bader DM (2005) J Cell Sci 118:4667-78 | 2005 |
| CASP6 assessment of contact prediction. Graña O, Baker D, MacCallum RM, Meiler J, Punta M, Rost B, Tress ML, Valencia A (2005) Proteins 61 Suppl 7:214-24 | 2005 |
| Free modeling with Rosetta in CASP6. Bradley P, Malmström L, Qian B, Schonbrun J, Chivian D, Kim DE, Meiler J, Misura KM, Baker D (2005) Proteins 61 Suppl 7:128-34 | 2005 |
| Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression. Muraoka-Cook RS, Shin I, Yi JY, Easterly E, Barcellos-Hoff MH, Yingling JM, Zent R, Arteaga CL (2006) Oncogene 25:3408-23 | 2006 |
| Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy. Pedchenko VK, Chetyrkin SV, Chuang P, Ham AJ, Saleem MA, Mathieson PW, Hudson BG, Voziyan PA (2005) Diabetes 54:2952-60 | 2005 |
| Novel collectin/C1q receptor mediates mast cell activation and innate immunity. Edelson BT, Stricker TP, Li Z, Dickeson SK, Shepherd VL, Santoro SA, Zutter MM (2006) Blood 107:143-50 | 2006 |
| Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression. Brantley-Sieders DM, Fang WB, Hicks DJ, Zhuang G, Shyr Y, Chen J (2005) FASEB J 19:1884-6 | 2005 |
| Plasminogen activator inhibitor-1 modulates adipocyte differentiation. Liang X, Kanjanabuch T, Mao SL, Hao CM, Tang YW, Declerck PJ, Hasty AH, Wasserman DH, Fogo AB, Ma LJ (2006) Am J Physiol Endocrinol Metab 290:E103-E113 | 2006 |
| Membranoproliferative injury pattern in a renal allograft. Gökden N, Rossini M, Kumar J, Fogo AB (2005) Am J Kidney Dis 46:573-6 | 2005 |
| Characterization of susceptibility of inbred mouse strains to diabetic nephropathy. Qi Z, Fujita H, Jin J, Davis LS, Wang Y, Fogo AB, Breyer MD (2005) Diabetes 54:2628-37 | 2005 |
| Dispersal of epithelial cancer cell colonies by lysophosphatidic acid (LPA). Jourquin J, Yang N, Kam Y, Guess C, Quaranta V (2006) J Cell Physiol 206:337-46 | 2006 |
| Role of integrin alpha1beta1 in the regulation of renal medullary osmolyte concentration. Moeckel GW, Zhang L, Chen X, Rossini M, Zent R, Pozzi A (2006) Am J Physiol Renal Physiol 290:F223-31 | 2006 |
| Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy. Zhong J, Zuo Y, Ma J, Fogo AB, Jolicoeur P, Ichikawa I, Matsusaka T (2005) Kidney Int 68:1048-60 | 2005 |
| A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis. Fang WB, Brantley-Sieders DM, Parker MA, Reith AD, Chen J (2005) Oncogene 24:7859-68 | 2005 |
| Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease. O'Donnell SM, Hansberger MW, Connolly JL, Chappell JD, Watson MJ, Pierce JM, Wetzel JD, Han W, Barton ES, Forrest JC, Valyi-Nagy T, Yull FE, Blackwell TS, Rottman JN, Sherry B, Dermody TS (2005) J Clin Invest 115:2341-50 | 2005 |
| Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages. Musiek ES, Gao L, Milne GL, Han W, Everhart MB, Wang D, Backlund MG, DuBois RN, Zanoni G, Vidari G, Blackwell TS, Morrow JD (2005) J Biol Chem 280:35562-70 | 2005 |
| Inducible binding of PU.1 and interacting proteins to the Toll-like receptor 4 promoter during endotoxemia. Pedchenko TV, Park GY, Joo M, Blackwell TS, Christman JW (2005) Am J Physiol Lung Cell Mol Physiol 289:L429-37 | 2005 |
| An orthotopic model of lung cancer to analyze primary and metastatic NSCLC growth in integrin alpha1-null mice. Chen X, Su Y, Fingleton B, Acuff H, Matrisian LM, Zent R, Pozzi A (2005) Clin Exp Metastasis 22:185-93 | 2005 |
| Proteomic patterns and prediction of glomerulosclerosis and its mechanisms. Xu BJ, Shyr Y, Liang X, Ma LJ, Donnert EM, Roberts JD, Zhang X, Kon V, Brown NJ, Caprioli RM, Fogo AB (2005) J Am Soc Nephrol 16:2967-75 | 2005 |
| LEK1 protein expression in normal and dysregulated cardiomyocyte mitosis. Dees E, Robertson JB, Ashe M, Pabón-Peña LM, Bader D, Goodwin RL (2005) Anat Rec A Discov Mol Cell Evol Biol 286:823-32 | 2005 |
| Pyridoxamine: the many virtues of a maillard reaction inhibitor. Voziyan PA, Hudson BG (2005) Ann N Y Acad Sci 1043:807-16 | 2005 |
| Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice. Ayabe N, Babaev VR, Tang Y, Tanizawa T, Fogo AB, Linton MF, Ichikawa I, Fazio S, Kon V (2006) Atherosclerosis 184:312-21 | 2006 |
| Chemokine receptor internalization and intracellular trafficking. Neel NF, Schutyser E, Sai J, Fan GH, Richmond A (2005) Cytokine Growth Factor Rev 16:637-58 | 2005 |
| Expression of mediators of renal injury in the remnant kidney of ROP mice is attenuated by cyclooxygenase-2 inhibition. Cheng H, Zhang M, Moeckel GW, Zhao Y, Wang S, Qi Z, Breyer MD, Harris RC (2005) Nephron Exp Nephrol 101:e75-85 | 2005 |
| NF-kappaB: a therapeutic target in inflammatory diseases. Curran CL, Blackwell TS, Christman JW (2001) Expert Opin Ther Targets 5:197-204 | 2001 |
| Permanent genetic tagging of podocytes: fate of injured podocytes in a mouse model of glomerular sclerosis. Asano T, Niimura F, Pastan I, Fogo AB, Ichikawa I, Matsusaka T (2005) J Am Soc Nephrol 16:2257-62 | 2005 |
| Role of nuclear factor-kappa B in melanoma. Amiri KI, Richmond A (2005) Cancer Metastasis Rev 24:301-13 | 2005 |
| The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice. Cheng Q, Zhao Y, Lawson WE, Polosukhin VV, Johnson JE, Blackwell TS, Gailani D (2005) Blood 106:3055-7 | 2005 |
| Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Singh AB, Harris RC (2005) Cell Signal 17:1183-93 | 2005 |
| A simplified laminin nomenclature. Aumailley M, Bruckner-Tuderman L, Carter WG, Deutzmann R, Edgar D, Ekblom P, Engel J, Engvall E, Hohenester E, Jones JC, Kleinman HK, Marinkovich MP, Martin GR, Mayer U, Meneguzzi G, Miner JH, Miyazaki K, Patarroyo M, Paulsson M, Quaranta V, Sanes JR, Sasaki T, Sekiguchi K, Sorokin LM, Talts JF, Tryggvason K, Uitto J, Virtanen I, von der Mark K, Wewer UM, Yamada Y, Yurchenco PD (2005) Matrix Biol 24:326-32 | 2005 |
| Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells. Mai W, Chen D, Ding T, Kim I, Park S, Cho SY, Chu JS, Liang D, Wang N, Wu D, Li S, Zhao P, Zent R, Wu G (2005) Mol Biol Cell 16:4398-409 | 2005 |
| Identification of S-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (NC1) hexamer of the alpha1alpha1alpha2 collagen IV network: a role for the post-translational modification of lysine 211 to hydroxylysine 211 in hexamer assembly. Vanacore RM, Friedman DB, Ham AJ, Sundaramoorthy M, Hudson BG (2005) J Biol Chem 280:29300-10 | 2005 |
| Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions. Kalomenidis I, Stathopoulos GT, Barnette R, Guo Y, Peebles RS, Blackwell TS, Light RW (2005) Chest 127:2094-100 | 2005 |
| Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway. Soukoulis V, Reddy S, Pooley RD, Feng Y, Walsh CA, Bader DM (2005) Proc Natl Acad Sci U S A 102:8549-54 | 2005 |
| Variability of interalveolar septal remodeling after bleomycin treatment in mice. Polosukhin VV, Stathopoulos GT, Lawson WE, Blackwell TS (2005) Ultrastruct Pathol 29:53-64 | 2005 |
| The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping. Sánchez-Pedregal VM, Reese M, Meiler J, Blommers MJ, Griesinger C, Carlomagno T (2005) Angew Chem Int Ed Engl 44:4172-5 | 2005 |
| Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. Joo M, Hahn YS, Kwon M, Sadikot RT, Blackwell TS, Christman JW (2005) J Virol 79:7648-57 | 2005 |
| Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. Pozzi A, Macias-Perez I, Abair T, Wei S, Su Y, Zent R, Falck JR, Capdevila JH (2005) J Biol Chem 280:27138-46 | 2005 |
| Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis. Borza DB, Bondar O, Colon S, Todd P, Sado Y, Neilson EG, Hudson BG (2005) J Biol Chem 280:27147-54 | 2005 |
| Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator. Walker GM, Sai J, Richmond A, Stremler M, Chung CY, Wikswo JP (2005) Lab Chip 5:611-8 | 2005 |
| Mathematical modeling of cancer: the future of prognosis and treatment. Quaranta V, Weaver AM, Cummings PT, Anderson AR (2005) Clin Chim Acta 357:173-9 | 2005 |
| Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage. Voziyan PA, Hudson BG (2005) Cell Mol Life Sci 62:1671-81 | 2005 |
| Renal effects of non-steroidal anti-inflammatory drugs and selective cyclooxygenase-2 inhibitors. Cheng HF, Harris RC (2005) Curr Pharm Des 11:1795-804 | 2005 |
| EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics. Ireton RC, Chen J (2005) Curr Cancer Drug Targets 5:149-57 | 2005 |
| GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. Sarratt KL, Chen H, Zutter MM, Santoro SA, Hammer DA, Kahn ML (2005) Blood 106:1268-77 | 2005 |
| Diabetic nephropathy: of mice and men. Breyer MD, Böttinger E, Brosius FC, Coffman TM, Fogo A, Harris RC, Heilig CW, Sharma K (2005) Adv Chronic Kidney Dis 12:128-45 | 2005 |
| New capillary growth: a contributor to regression of sclerosis? Fogo AB (2005) Curr Opin Nephrol Hypertens 14:201-3 | 2005 |
| Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. Chen JK, Chen J, Neilson EG, Harris RC (2005) J Am Soc Nephrol 16:1384-91 | 2005 |
| Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. Schutyser E, Richmond A, Van Damme J (2005) J Leukoc Biol 78:14-26 | 2005 |
| Expression and nuclear location of the transcriptional repressor Kaiso is regulated by the tumor microenvironment. Soubry A, van Hengel J, Parthoens E, Colpaert C, Van Marck E, Waltregny D, Reynolds AB, van Roy F (2005) Cancer Res 65:2224-33 | 2005 | <