Publications

Explore the wealth of knowledge and discovery through our publications


Publications

Publications represent the final product of research. The hypothesis, methods, data, analysis and conclusions are all wrapped into papers for others to learn from and build atop of.

Source: CMB faculty-derived publications, via Labnodes
  Publication Year
High-Fat, High-Sugar Diet-Induced Subendothelial Matrix Stiffening is Mitigated by Exercise. Kohn JC, Azar J, Seta F, Reinhart-King CA (2017) Cardiovasc Eng Technol 2017
Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis. Dear ML, Shilts J, Broadie K (2017) Sci Signal 102017
The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain. Dohn MR, Kooker CG, Bastarache L, Jessen T, Rinaldi C, Varney S, Mazalouskas MD, Pan H, Oliver KH, Velez Edwards DR, Sutcliffe JS, Denny JC, Carneiro AMD (2017) J Neurosci 2017
Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development. Mathew S, Palamuttam RJ, Mernaugh G, Ramalingam H, Lu Z, Zhang MZ, Ishibe S, Critchley DR, Fässler R, Pozzi A, Sanders CR, Carroll TJ, Zent R (2017) Development 144:4148-41582017
Proteolytic processing of lysyl oxidase-like-2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV. López-Jiménez AJ, Basak T, Vanacore RM (2017) J Biol Chem 292:16970-169822017
Building collagen IV smart scaffolds on the outside of cells. Brown KL, Cummings CF, Vanacore RM, Hudson BG (2017) Protein Sci 26:2151-21612017
The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells. Jerrell RJ, Leih MJ, Parekh A (2017) Small GTPases 2017
Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca(2+)-Regulated Genes. Stancill JS, Cartailler JP, Clayton HW, O'Connor JT, Dickerson MT, Dadi PK, Osipovich AB, Jacobson DA, Magnuson MA (2017) Diabetes 2017
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR (2017) Nature 545:243-2472017
The Vascular Wall: a Plastic Hub of Activity in Cardiovascular Homeostasis and Disease. Awgulewitsch CP, Trinh LT, Hatzopoulos AK (2017) Curr Cardiol Rep 19:512017
The sulfilimine cross-link of collagen IV contributes to kidney tubular basement membrane stiffness. Bhave G, Colon S, Ferrell N (2017) Am J Physiol Renal Physiol 313:F596-F6022017
Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues. Fidler AL, Darris CE, Chetyrkin SV, Pedchenko VK, Boudko SP, Brown KL, Gray Jerome W, Hudson JK, Rokas A, Hudson BG (2017) Elife 62017
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation. Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schröder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J (2017) J Clin Invest 2017
Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again! Wooten DJ, Quaranta V (2017) Biochim Biophys Acta 2017
Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. Hockman D, Burns AJ, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PD, Lickert H, Tucker AS, Baker CV (2017) Elife 62017
Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue. Jovanović B, Sheng Q, Seitz RS, Lawrence KD, Morris SW, Thomas LR, Hout DR, Schweitzer BL, Guo Y, Pietenpol JA, Lehmann BD (2017) BMC Cancer 17:2412017
Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Minciacchi VR, Zijlstra A, Rubin MA, Di Vizio D (2017) Prostate Cancer Prostatic Dis 2017
The susceptible HLA class II alleles and their presenting epitope(s) in Goodpasture's disease. Xie LJ, Cui Z, Chen FJ, Pei ZY, Hu SY, Gu QH, Jia XY, Zhu L, Zhou XJ, Zhang H, Liao YH, Lai LH, Hudson BG, Zhao MH (2017) Immunology 2017
FSTL3 is increased in renal dysfunction. Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T (2017) Nephrol Dial Transplant 2017
The Innate Immune Response in Fetal Lung Mesenchymal Cells Targets VEGFR2 Expression and Activity. Medal RM, Im AM, Yamamoto Y, Lakhdari O, Blackwell TS, Hoffman HM, Sahoo D, Prince LS (2017) Am J Physiol Lung Cell Mol Physiol ajplung.00554.20162017
Zebrafish Developmental Models of Skeletal Diseases. Luderman LN, Unlu G, Knapik EW (2017) Curr Top Dev Biol 124:81-1242017
A mechanically coupled reaction-diffusion model that incorporates intra-tumoural heterogeneity to predict in vivo glioma growth. Hormuth DA, Weis JA, Barnes SL, Miga MI, Rericha EC, Quaranta V, Yankeelov TE (2017) J R Soc Interface 142017
Both Drosophila matrix metalloproteinases have released and membrane-tethered forms but have different substrates. LaFever KS, Wang X, Page-McCaw P, Bhave G, Page-McCaw A (2017) Sci Rep 7:445602017
An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer. Hanker AB, Red Brewer M, Sheehan JH, Koch JP, Sliwoski GR, Nagy R, Lanman R, Berger MF, Hyman DM, Solit DB, He J, Miller V, Cutler RE, Lalani AS, Cross D, Lovly CM, Meiler J, Arteaga CL (2017) Cancer Discov 2017
A randomized phase II neoadjuvant study of cisplatin, paclitaxel with or without everolimus in patients with stage II/III triple-negative breast cancer (TNBC). Jovanovic B, Mayer IA, Mayer EL, Abramson VG, Bardia A, Sanders M, Kuba MG, Estrada MV, Beeler JS, Shaver TM, Johnson KN, Sanchez V, Rosenbluth JM, Dillon PM, Forrero-Torres A, Chang JC, Meszoely I, Grau A, Lehmann BD, Shyr Y, Sheng Q, Chen SC, Arteaga CL, Pietenpol JA (2017) Clin Cancer Res 2017
Improving prediction of helix-helix packing in membrane proteins using predicted contact numbers as restraints. Li B, Mendenhall J, Nguyen ED, Weiner BE, Fischer AW, Meiler J (2017) Proteins 2017
Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis. Bankaitis K, Borriello L, Cox T, Lynch C, Zijlstra A, Fingleton B, Gužvić M, Anderson R, Neman J (2017) Clin Exp Metastasis 2017
Connecting Imaging Mass Spectrometry and Magnetic Resonance Imaging-based Anatomical Atlases for Automated Anatomical Interpretation and Differential Analysis. Verbeeck N, Spraggins JM, Murphy MJ, Wang HD, Deutch AY, Caprioli RM, de Plas RV (2017) Biochim Biophys Acta 2017
Mass Spectrometry Imaging Can Distinguish on a Proteomic Level Between Proliferative Nodules Within a Benign Congenital Nevus and Malignant Melanoma. Lazova R, Yang Z, El Habr C, Lim Y, Choate KA, Seeley EH, Caprioli RM, Yangqun L (2017) Am J Dermatopathol 2017
Development of novel murine mammary imaging windows to examine wound healing effects on leukocyte trafficking in mammary tumors with intravital imaging. Sobolik T, Su YJ, Ashby W, Schaffer DK, Wells S, Wikswo JP, Zijlstra A, Richmond A (2016) Intravital 5:e11255622016
High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling. Prentice BM, Chumbley CW, Caprioli RM (2016) J Mass Spectrom 51:6652016
The novel adipokine/hepatokine fetuin B in severe human and murine diabetic kidney disease. Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T (2017) Diabetes Metab 2017
Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition. Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP (2017) Sci Rep 7:426042017
Identification of a Novel Series of Anti-inflammatory and Anti-oxidative Phospholipid Oxidation Products Containing Cyclopentenone Moiety in vitro and in vivo: Implication in Atherosclerosis. Lu J, Guo S, Xue X, Chen Q, Ge J, Zhuo Y, Zhong H, Chen B, Zhao M, Han W, Suzuki T, Zhu M, Xia L, Schneider C, Blackwell TS, Porter NA, Zheng L, Tsimikas S, Yin H (2017) J Biol Chem 2017
Enhanced Spatially Resolved Proteomics Using On-Tissue Hydrogel-Mediated Protein Digestion. Rizzo DG, Prentice BM, Moore JL, Norris JL, Caprioli RM (2017) Anal Chem 89:2948-29552017
Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors. Polosukhina D, Love HD, Correa H, Su Z, Dahlman KB, Pao W, Moses HL, Arteaga CL, Lovvorn HN, Zent R, Clark PE (2017) Mol Oncol 11:405-4212017
In vivo histone H1 migration from necrotic to viable tissue. Luhrs KA, Pink D, Schulte W, Zijlstra A, Lewis JD, Parseghian MH (2017) Oncotarget 2017
The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo. Lavender N, Yang J, Chen SC, Sai J, Johnson CA, Owens P, Ayers GD, Richmond A (2017) BMC Cancer 17:882017
Larger core size has superior technical and analytical accuracy in bladder tissue microarray. Eskaros AR, Egloff SA, Boyd KL, Richardson JE, Hyndman ME, Zijlstra A (2017) Lab Invest 97:335-3422017
Strategies to overcome therapeutic resistance in renal cell carcinoma. Siska PJ, Beckermann KE, Rathmell WK, Haake SM (2017) Urol Oncol 35:102-1102017
Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action. Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei YW, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM (2017) J Proteome Res 16:1364-13752017
Bortezomib augments lymphocyte stimulatory cytokine signaling in the tumor microenvironment to sustain CD8+T cell antitumor function. Pellom ST, Dudimah DF, Thounaojam MC, Uzhachenko RV, Singhal A, Richmond A, Shanker A (2017) Oncotarget 8:8604-86212017
Integrin alpha6 maintains the structural integrity of the kidney collecting system. Viquez OM, Yazlovitskaya EM, Tu T, Mernaugh G, Secades P, McKee KK, Georges-Labouesse E, De Arcangelis A, Quaranta V, Yurchenco P, Gewin LC, Sonnenberg A, Pozzi A, Zent R (2017) Matrix Biol 57-58:244-2572017
PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Anti-tumor Immunity and Anti-PD1 Responses. Sai J, Owens P, Novitiskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik-Delmaire T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A (2016) Clin Cancer Res 2016
Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors. Cowen SD, Russell D, Dakin LA, Chen H, Larsen NA, Godin R, Throner S, Zheng X, Molina A, Wu J, Cheung T, Howard T, Garcia-Arenas R, Keen N, Pendleton CS, Pietenpol JA, Ferguson AD (2016) J Med Chem 59:11079-110972016
MALDI Imaging Mass Spectrometry as a Lipidomic Approach to Heart Valve Research. Angel PM, Bayoumi AS, Hinton RB, Ru Su Y, Bichell D, Mayer JE, Scott Baldwin H, Caprioli RM (2016) J Heart Valve Dis 25:240-2522016
Novel hybrid phenotype revealed in Small Cell Lung Cancer by a transcription factor network model that can explain tumor heterogeneity. Udyavar AR, Wooten DJ, Hoeksema MD, Bansal M, Califano A, Estrada L, Schnell S, Irish JM, Massion PP, Quaranta V (2016) Cancer Res 2016
Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function. Lu Z, Mathew S, Chen J, Hadziselimovic A, Palamuttam R, Hudson BG, Fässler R, Pozzi A, Sanders CR, Zent R (2016) Elife 52016
Life history linked to immune investment in developing amphibians. Woodhams DC, Bell SC, Bigler L, Caprioli RM, Chaurand P, Lam BA, Reinert LK, Stalder U, Vazquez VM, Schliep K, Hertz A, Rollins-Smith LA (2016) Conserv Physiol 4:cow0252016
Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP (2016) Nat Med 22:15022016
Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis. Borza CM, Su Y, Tran TL, Yu L, Steyns N, Temple KJ, Skwark MJ, Meiler J, Lindsley CW, Hicks BR, Leitinger B, Zent R, Pozzi A (2017) Matrix Biol 57-58:258-2712017
SIgA Deficiency in Individual Small Airways is Associated with Persistent Inflammation and Remodeling. Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS (2016) Am J Respir Crit Care Med 2016
Micrometastatic Dormancy in Uveal Melanoma: A Comprehensive Review of the Evidence, Mechanisms, and Implications for Future Adjuvant Therapies. Nichols EE, Richmond A, Daniels AB (2017) Int Ophthalmol Clin 57:1-102017
Basement membrane ultrastructure and component localization data from uterine tissues during early mouse pregnancy. Jones-Paris CR, Paria S, Berg T, Saus J, Bhave G, Paria BC, Hudson BG (2016) Data Brief 9:931-9392016
Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer. Arnold Egloff SA, Du L, Loomans HA, Starchenko A, Su PF, Ketova T, Knoll PB, Wang J, Haddad AQ, Fadare O, Cates JM, Lotan Y, Shyr Y, Clark PE, Zijlstra A (2017) Oncotarget 8:722-7412017
A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y2 R Antagonists. Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG (2017) ChemMedChem 12:75-852017
Renal cancer subtypes: Should we be lumping or splitting for therapeutic decision making? Haake SM, Rathmell WK (2017) Cancer 123:200-2092017
Evaluation of TSPO PET Ligands [(18)F]VUIIS1009A and [(18)F]VUIIS1009B: Tracers for Cancer Imaging. Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC (2016) Mol Imaging Biol 2016
Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens aging. Nye-Wood MG, Spraggins JM, Caprioli RM, Schey KL, Donaldson PJ, Grey AC (2017) Exp Eye Res 154:70-782017
MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions. Weck ML, Grega-Larson NE, Tyska MJ (2016) Curr Opin Cell Biol 2016
TβRIII Expression in Human Breast Cancer Stroma and the Role of Soluble TβRIII in Breast Cancer Associated Fibroblasts. Jovanović B, Pickup MW, Chytil A, Gorska AE, Johnson KC, Moses HL, Owens P (2016) Cancers (Basel) 82016
bcl::Cluster : A method for clustering biological molecules coupled with visualization in the Pymol Molecular Graphics System. Alexander N, Woetzel N, Meiler J (2011) IEEE Int Conf Comput Adv Bio Med Sci 2011:13-182011
Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy. Wang X, Yao B, Wang Y, Fan X, Wang S, Niu A, Yang H, Fogo A, Zhang MZ, Harris RC (2017) Diabetes 66:494-5042017
Eph Receptor Tyrosine Kinases in Tumor Immunity. Shiuan E, Chen J (2016) Cancer Res 76:6452-64572016
Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Meiler J, Crowe JE (2016) Proc Natl Acad Sci U S A 113:E6849-E68582016
Genetic Evaluation and Testing of Patients and Families with Idiopathic Pulmonary Fibrosis. Kropski JA, Young LR, Cogan JD, Mitchell DB, Lancaster LH, Worrell JA, Markin C, Liu N, Mason WR, Fingerlin TE, Schwartz DA, Lawson WE, Blackwell TS, Phillips Iii JA, Loyd JE (2016) Am J Respir Crit Care Med 2016
LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer). Simonik EA, Cai Y, Kimmelshue KN, Brantley-Sieders DM, Loomans HA, Andl CD, Westlake GM, Youngblood VM, Chen J, Yarbrough WG, Brown BT, Nagarajan L, Brandt SJ (2016) PLoS One 11:e01648042016
Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome. Young LR, Gulleman PM, Short CW, Tanjore H, Sherrill T, Qi A, McBride AP, Zaynagetdinov R, Benjamin JT, Lawson WE, Novitskiy SV, Blackwell TS (2016) JCI Insight 1:e889472016
Progression of chronic kidney disease: too much cellular talk causes damage. Gewin L, Zent R, Pozzi A (2016) Kidney Int 2016
Lysyl Oxidase-like-2 Cross-links Collagen IV of Glomerular Basement Membrane. Añazco C, López-Jiménez AJ, Rafi M, Vega-Montoto L, Zhang MZ, Hudson BG, Vanacore RM (2016) J Biol Chem 291:25999-260122016
mTORC1 and mTORC2 in cancer and the tumor microenvironment. Kim LC, Cook RS, Chen J (2016) Oncogene 2016
Improved prediction of trans-membrane spans in proteins using an Artificial Neural Network. Koehler J, Mueller R, Meiler J (2009) IEEE Symp Comput Intell Bioinforma Comput Biol Proc 2009:68-742009
IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury. Zhang MZ, Wang X, Wang Y, Niu A, Wang S, Zou C, Harris RC (2017) Kidney Int 91:375-3862017
Developmental experience-dependent plasticity in the first synapse of the Drosophila olfactory circuit. Golovin RM, Broadie K (2016) J Neurophysiol 116:2730-27382016
Trypsin and MALDI matrix pre-coated targets simplify sample preparation for mapping proteomic distributions within biological tissues by imaging mass spectrometry. Zubair F, Laibinis PE, Swisher WG, Yang J, Spraggins JM, Norris JL, Caprioli RM (2016) J Mass Spectrom 51:1168-11792016
Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP (2016) Nat Med 22:1330-13342016
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex. Weck ML, Crawley SW, Stone CR, Tyska MJ (2016) Curr Biol 26:2717-27282016
Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Events in a Single Laser Shot. Prentice BM, Chumbley CW, Caprioli RM (2017) J Am Soc Mass Spectrom 28:136-1442017
Structural basis for KCNE3 modulation of potassium recycling in epithelia. Kroncke BM, Van Horn WD, Smith J, Kang C, Welch RC, Song Y, Nannemann DP, Taylor KC, Sisco NJ, George AL, Meiler J, Vanoye CG, Sanders CR (2016) Sci Adv 2:e15012282016
Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit during uterine reprogramming. Jones-Paris CR, Paria S, Berg T, Saus J, Bhave G, Paria BC, Hudson BG (2016) Matrix Biol 2016
Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation. Borza DB (2016) Matrix Biol 2016
Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions. Raval MH, Quintero OA, Weck ML, Unrath WC, Gallagher JW, Cui R, Kachar B, Tyska MJ, Yengo CM (2016) J Biol Chem 291:22781-227922016
Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Quantification. Prentice BM, Chumbley CW, Hachey BC, Norris JL, Caprioli RM (2016) Anal Chem 88:9780-97882016
A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD. Parsons ZD, Bland JM, Mullins EA, Eichman BF (2016) J Am Chem Soc 138:11485-82016
The Need for Speed in Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry. Prentice BM, Caprioli RM (2016) Postdoc J 4:3-132016
Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability. Kroncke BM, Duran AM, Mendenhall JL, Meiler J, Blume JD, Sanders CR (2016) Biochemistry 55:5002-92016
Correction to Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues. Chumbley CW, Reyzer ML, Allen JL, Marriner GA, Via LE, Barry CE, Caprioli RM (2016) Anal Chem 88:89202016
Patterning protein complexes on DNA nanostructures using a GFP nanobody. Sommese RF, Hariadi RF, Kim K, Liu M, Tyska MJ, Sivaramakrishnan S (2016) Protein Sci 25:2089-20942016
Development of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer. Ludwik KA, Campbell JP, Li M, Li Y, Sandusky ZM, Pasic L, Sowder ME, Brenin DR, Pietenpol JA, O'Doherty GA, Lannigan DA (2016) Mol Cancer Ther 15:2598-26082016
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes. Geanes AR, Cho HP, Nance KD, McGowan KM, Conn PJ, Jones CK, Meiler J, Lindsley CW (2016) Bioorg Med Chem Lett 26:4487-912016
Imaging mass spectrometry assists in the classification of diagnostically challenging atypical Spitzoid neoplasms. Lazova R, Seeley EH, Kutzner H, Scolyer RA, Scott G, Cerroni L, Fried I, Kozovska ME, Rosenberg AS, Prieto VG, Shehata BM, Durham MM, Henry G, Rodriguez-Peralto JL, Riveiro-Falkenbach E, Schaefer JT, Danialan R, Fraitag S, Vollenweider-Roten S, Sepehr A, Sangueza M, Hijazi N, Corredoira Y, Kowal R, Harris OM, Bravo F, Boyd AS, Gueorguieva R, Caprioli RM (2016) J Am Acad Dermatol 75:1176-1186.e42016
Protocols for Molecular Modeling with Rosetta3 and RosettaScripts. Bender BJ, Cisneros A, Duran AM, Finn JA, Fu D, Lokits AD, Mueller BK, Sangha AK, Sauer MF, Sevy AM, Sliwoski G, Sheehan JH, DiMaio F, Meiler J, Moretti R (2016) Biochemistry 55:4748-632016
Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment. Saxon JA, Sherrill TP, Polosukhin VV, Sai J, Zaynagetdinov R, McLoed AG, Gulleman PM, Barham W, Cheng DS, Hunt RP, Gleaves LA, Richmond A, Young LR, Yull FE, Blackwell TS (2016) Oncoimmunology 5:e11685492016
Coordinated movement, neuromuscular synaptogenesis and trans-synaptic signaling defects in Drosophila galactosemia models. Jumbo-Lucioni PP, Parkinson WM, Kopke DL, Broadie K (2016) Hum Mol Genet 25:3699-37142016
Impact of cordon-bleu expression on actin cytoskeleton architecture and dynamics. Grega-Larson NE, Crawley SW, Tyska MJ (2016) Cytoskeleton (Hoboken) 73:670-6792016
A Conserved Hydrophobic Core in Gαi1 Regulates G Protein Activation and Release from Activated Receptor. Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE (2016) J Biol Chem 291:19674-862016
Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Taneja N, Fenix AM, Rathbun L, Millis BA, Tyska MJ, Hehnly H, Burnette DT (2016) Sci Rep 6:298462016
Loss of Serotonin Transporter Function Alters ADP-mediated Glycoprotein αIIbβ3 Activation through Dysregulation of the 5-HT2A Receptor. Oliver KH, Duvernay MT, Hamm HE, Carneiro AM (2016) J Biol Chem 291:20210-92016
Cortactin promotes exosome secretion by controlling branched actin dynamics. Sinha S, Hoshino D, Hong NH, Kirkbride KC, Grega-Larson NE, Seiki M, Tyska MJ, Weaver AM (2016) J Cell Biol 214:197-2132016
Altered TGF-α/β signaling drives cooperation between breast cancer cell populations. Franco OE, Tyson DR, Konvinse KC, Udyavar AR, Estrada L, Quaranta V, Crawford SE, Hayward SW (2016) FASEB J 30:3441-34522016
Telomerase, Autophagy and Acute Kidney Injury. Harris RC, Cheng H (2016) Nephron 134:145-1482016
Biomarker Tests for Molecularly Targeted Therapies--The Key to Unlocking Precision Medicine. Lyman GH, Moses HL (2016) N Engl J Med 375:4-62016
Insights into the Genetic Basis of the Renal Cell Carcinomas from The Cancer Genome Atlas. Haake SM, Weyandt JD, Rathmell WK (2016) Mol Cancer Res 14:589-982016
The Discovery and Early Days of TGF-β: A Historical Perspective. Moses HL, Roberts AB, Derynck R (2016) Cold Spring Harb Perspect Biol 82016
Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer. McLoed AG, Sherrill TP, Cheng DS, Han W, Saxon JA, Gleaves LA, Wu P, Polosukhin VV, Karin M, Yull FE, Stathopoulos GT, Georgoulias V, Zaynagetdinov R, Blackwell TS (2016) Cell Rep 16:120-322016
Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection. Lehmann BD, Jovanović B, Chen X, Estrada MV, Johnson KN, Shyr Y, Moses HL, Sanders ME, Pietenpol JA (2016) PLoS One 11:e01573682016
The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction. Wakeman CA, Moore JL, Noto MJ, Zhang Y, Singleton MD, Prentice BM, Gilston BA, Doster RS, Gaddy JA, Chazin WJ, Caprioli RM, Skaar EP (2016) Nat Commun 7:119512016
Standard Reticle Slide To Objectively Evaluate Spatial Resolution and Instrument Performance in Imaging Mass Spectrometry. Zubair F, Prentice BM, Norris JL, Laibinis PE, Caprioli RM (2016) Anal Chem 88:7302-112016
Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis. Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP (2016) Laryngoscope 126:E356-E3612016
Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species. Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP (2017) Laryngoscope 127:179-1852017
Discovery of Small-Molecule Modulators of the Human Y4 Receptor. Sliwoski G, Schubert M, Stichel J, Weaver D, Beck-Sickinger AG, Meiler J (2016) PLoS One 11:e01571462016
Combinatorial approach to cancer immunotherapy: strength in numbers. Vilgelm AE, Johnson DB, Richmond A (2016) J Leukoc Biol 100:275-902016
A Derived Allosteric Switch Underlies the Evolution of Conditional Cooperativity between HOXA11 and FOXO1. Nnamani MC, Ganguly S, Erkenbrack EM, Lynch VJ, Mizoue LS, Tong Y, Darling HL, Fuxreiter M, Meiler J, Wagner GP (2016) Cell Rep 15:2097-1082016
Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies. Shaver TM, Lehmann BD, Beeler JS, Li CI, Li Z, Jin H, Stricker TP, Shyr Y, Pietenpol JA (2016) Cancer Res 76:4850-602016
Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion. Zeng F, Kloepfer LA, Finney C, Diedrich A, Harris RC (2016) Am J Physiol Renal Physiol 311:F695-F7072016
Tyrosine Kinase Signaling in Clear Cell and Papillary Renal Cell Carcinoma Revealed by Mass Spectrometry-Based Phosphotyrosine Proteomics. Haake SM, Li J, Bai Y, Kinose F, Fang B, Welsh EA, Zent R, Dhillon J, Pow-Sang JM, Chen YA, Koomen JM, Rathmell WK, Fishman M, Haura EB (2016) Clin Cancer Res 2016
Extracellular chloride signals collagen IV network assembly during basement membrane formation. Cummings CF, Pedchenko V, Brown KL, Colon S, Rafi M, Jones-Paris C, Pokydeshava E, Liu M, Pastor-Pareja JC, Stothers C, Ero-Tolliver IA, McCall AS, Vanacore R, Bhave G, Santoro S, Blackwell TS, Zent R, Pozzi A, Hudson BG (2016) J Cell Biol 213:479-942016
Integrin α1β1 protects against signs of post-traumatic osteoarthritis in the female murine knee partially via regulation of epidermal growth factor receptor signalling. Shin SY, Pozzi A, Boyd SK, Clark AL (2016) Osteoarthritis Cartilage 24:1795-8062016
Changes in the Fracture Resistance of Bone with the Progression of Type 2 Diabetes in the ZDSD Rat. Creecy A, Uppuganti S, Merkel AR, O'Neal D, Makowski AJ, Granke M, Voziyan P, Nyman JS (2016) Calcif Tissue Int 99:289-3012016
Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice. Kang L, Mokshagundam S, Reuter B, Lark DS, Sneddon CC, Hennayake C, Williams AS, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH (2016) Diabetes 65:1590-6002016
Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy. Borza DB (2016) Front Immunol 7:1572016
Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. Skrypnyk NI, Voziyan P, Yang H, de Caestecker CR, Theberge MC, Drouin M, Hudson B, Harris RC, de Caestecker MP (2016) Am J Physiol Renal Physiol 311:F268-772016
Using avatars to win the fight over BRAF inhibitor resistance. Vilgelm AE, Richmond A (2016) Pigment Cell Melanoma Res 29:398-92016
ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS (2016) ACS Chem Neurosci 7:1013-232016
Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints. Finn JA, Koehler Leman J, Willis JR, Cisneros A, Crowe JE, Meiler J (2016) PLoS One 11:e01548112016
The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools. Figueroa M, Sleutel M, Vandevenne M, Parvizi G, Attout S, Jacquin O, Vandenameele J, Fischer AW, Damblon C, Goormaghtigh E, Valerio-Lepiniec M, Urvoas A, Durand D, Pardon E, Steyaert J, Minard P, Maes D, Meiler J, Matagne A, Martial JA, Van de Weerdt C (2016) J Struct Biol 195:19-302016
Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury. Laskowski J, Renner B, Le Quintrec M, Panzer S, Hannan JP, Ljubanovic D, Ruseva MM, Borza DB, Antonioli AH, Pickering MC, Holers VM, Thurman JM (2016) Kidney Int 90:109-222016
Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities. Pfaltzgraff ER, Roth GM, Miller PM, Gintzig AG, Ohi R, Bader DM (2016) Mol Biol Cell 27:1990-92016
Celebrating the ASN at 50. Harris RC, Ibrahim T, Nath KA (2016) J Am Soc Nephrol 27:1575-62016
An unbiased metric of antiproliferative drug effect in vitro. Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR (2016) Nat Methods 13:497-5002016
Pushing the size limit of de novo structure ensemble prediction guided by sparse SDSL-EPR restraints to 200 residues: The monomeric and homodimeric forms of BAX. Fischer AW, Bordignon E, Bleicken S, García-Sáez AJ, Jeschke G, Meiler J (2016) J Struct Biol 195:62-712016
Rearrangement of the Extracellular Domain/Extracellular Loop 1 Interface Is Critical for Thyrotropin Receptor Activation. Schaarschmidt J, Nagel MB, Huth S, Jaeschke H, Moretti R, Hintze V, von Bergen M, Kalkhof S, Meiler J, Paschke R (2016) J Biol Chem 291:14095-1082016
Tumor Characteristics, Genetics, Management, and the Risk of Metastasis in Uveal Melanoma. Nichols EE, Richmond A, Daniels AB (2016) Semin Ophthalmol 31:304-92016
Disparities in Uveal Melanoma: Patient Characteristics. Nichols EE, Richmond A, Daniels AB (2016) Semin Ophthalmol 31:296-3032016
Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Mont S, Davies SS, Roberts Second LJ, Mernaugh RL, McDonald WH, Segal BH, Zackert W, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Massion PP, Marnett LJ, Travis EL, Freeman ML (2016) Sci Rep 6:249192016
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Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions. Zhang LS, Davies SS (2016) Genome Med 8:462016
EGFR Fusions as Novel Therapeutic Targets in Lung Cancer. Konduri K, Gallant JN, Chae YK, Giles FJ, Gitlitz BJ, Gowen K, Ichihara E, Owonikoko TK, Peddareddigari V, Ramalingam SS, Reddy SK, Eaby-Sandy B, Vavalà T, Whiteley A, Chen H, Yan Y, Sheehan JH, Meiler J, Morosini D, Ross JS, Stephens PJ, Miller VA, Ali SM, Lovly CM (2016) Cancer Discov 6:601-112016
Rosetta and the Design of Ligand Binding Sites. Moretti R, Bender BJ, Allison B, Meiler J (2016) Methods Mol Biol 1414:47-622016
Silent Cerebral Small Vessel Disease in Restless Legs Syndrome. Ferri R, Cosentino FI, Moussouttas M, Lanuzza B, Aricò D, Bagai K, Wang L, McLaughlin B, Walters AS (2016) Sleep 39:1371-72016
Erratum to: Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients. Ring BZ, Hout DR, Morris SW, Lawrence K, Schweitzer BL, Bailey DB, Lehmann BD, Pietenpol JA, Seitz RS (2016) BMC Cancer 16:2752016
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM (2016) Nat Med 22:497-5052016
Biomarker Tests for Molecularly Targeted Therapies: Laying the Foundation and Fulfilling the Dream. Lyman GH, Moses HL (2016) J Clin Oncol 34:2061-62016
Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. Weber MR, Zuka M, Lorger M, Tschan M, Torbett BE, Zijlstra A, Quigley JP, Staflin K, Eliceiri BP, Krueger JS, Marchese P, Ruggeri ZM, Felding BH (2016) Thromb Res 140 Suppl 1:S27-362016
CASP11--An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline. Fischer AW, Heinze S, Putnam DK, Li B, Pino JC, Xia Y, Lopez CF, Meiler J (2016) PLoS One 11:e01525172016
Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization. Willis JR, Finn JA, Briney B, Sapparapu G, Singh V, King H, LaBranche CC, Montefiori DC, Meiler J, Crowe JE (2016) Proc Natl Acad Sci U S A 113:4446-512016
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Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress. Federspiel JD, Codreanu SG, Palubinsky AM, Winland AJ, Betanzos CM, McLaughlin B, Liebler DC (2016) Mol Cell Proteomics 15:1947-612016
The impact of bone morphogenetic protein 4 (BMP4) on breast cancer metastasis in a mouse xenograft model. Ampuja M, Alarmo EL, Owens P, Havunen R, Gorska AE, Moses HL, Kallioniemi A (2016) Cancer Lett 375:238-442016
Origin and prediction of free-solution interaction studies performed label-free. Bornhop DJ, Kammer MN, Kussrow A, Flowers RA, Meiler J (2016) Proc Natl Acad Sci U S A 113:E1595-6042016
Structure and mechanism of the phage T4 recombination mediator protein UvsY. Gajewski S, Waddell MB, Vaithiyalingam S, Nourse A, Li Z, Woetzel N, Alexander N, Meiler J, White SW (2016) Proc Natl Acad Sci U S A 113:3275-802016
Data publication with the structural biology data grid supports live analysis. Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P (2016) Nat Commun 7:108822016
p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network. Marshall CB, Mays DJ, Beeler JS, Rosenbluth JM, Boyd KL, Santos Guasch GL, Shaver TM, Tang LJ, Liu Q, Shyr Y, Venters BJ, Magnuson MA, Pietenpol JA (2016) Cell Rep 14:2289-3002016
The role of NF-kB in modulating antitumor immunity. Richmond A, Yang J (2016) Oncoimmunology 5:e10055222016
Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model. Parkinson WM, Dookwah M, Dear ML, Gatto CL, Aoki K, Tiemeyer M, Broadie K (2016) Dis Model Mech 9:513-272016
Novel methods for microCT-based analyses of vasculature in the renal cortex reveal a loss of perfusable arterioles and glomeruli in eNOS-/- mice. Perrien DS, Saleh MA, Takahashi K, Madhur MS, Harrison DG, Harris RC, Takahashi T (2016) BMC Nephrol 17:242016
Study of Chemotaxis and Cell-Cell Interactions in Cancer with Microfluidic Devices. Sai J, Rogers M, Hockemeyer K, Wikswo JP, Richmond A (2016) Methods Enzymol 570:19-452016
Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients. Ring BZ, Hout DR, Morris SW, Lawrence K, Schweitzer BL, Bailey DB, Lehmann BD, Pietenpol JA, Seitz RS (2016) BMC Cancer 16:1432016
BVES Regulates Intestinal Stem Cell Programs and Intestinal Crypt Viability after Radiation. Reddy VK, Short SP, Barrett CW, Mittal MK, Keating CE, Thompson JJ, Harris EI, Revetta F, Bader DM, Brand T, Washington MK, Williams CS (2016) Stem Cells 34:1626-362016
Identification of a Substrate Recognition Domain in the Replication Stress Response Protein Zinc Finger Ran-binding Domain-containing Protein 3 (ZRANB3). Badu-Nkansah A, Mason AC, Eichman BF, Cortez D (2016) J Biol Chem 291:8251-72016
3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated optic glioma. Anderson DM, Van de Plas R, Rose KL, Hill S, Schey KL, Solga AC, Gutmann DH, Caprioli RM (2016) J Proteomics 149:77-842016
Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma. Marien E, Meister M, Muley T, Gomez Del Pulgar T, Derua R, Spraggins JM, Van de Plas R, Vanderhoydonc F, Machiels J, Binda MM, Dehairs J, Willette-Brown J, Hu Y, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Lacal JC, Waelkens E, Swinnen JV (2016) Oncotarget 7:12582-972016
Pragmatic pharmacology: population pharmacokinetic analysis of fentanyl using remnant samples from children after cardiac surgery. Van Driest SL, Marshall MD, Hachey B, Beck C, Crum K, Owen J, Smith AH, Kannankeril PJ, Woodworth A, Caprioli RM, Choi L (2016) Br J Clin Pharmacol 81:1165-742016
Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry. Doll CA, Broadie K (2016) Neurobiol Dis 89:76-872016
Improving quantitative structure-activity relationship models using Artificial Neural Networks trained with dropout. Mendenhall J, Meiler J (2016) J Comput Aided Mol Des 30:177-892016
Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2. Jerrell RJ, Parekh A (2016) Biomaterials 84:119-292016
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, Irish JM, Shyr Y, Sullivan RJ, Puzanov I, Sosman JA, Balko JM (2016) Nat Commun 7:105822016
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. Theodosiou M, Widmaier M, Böttcher RT, Rognoni E, Veelders M, Bharadwaj M, Lambacher A, Austen K, Müller DJ, Zent R, Fässler R (2016) Elife 5:e101302016
Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss. Jolly LA, Novitskiy S, Owens P, Massoll N, Cheng N, Fang W, Moses HL, Franco AT (2016) Cancer Res 76:1804-132016
Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues. Chumbley CW, Reyzer ML, Allen JL, Marriner GA, Via LE, Barry CE, Caprioli RM (2016) Anal Chem 88:2392-82016
ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation. Crawley SW, Weck ML, Grega-Larson NE, Shifrin DA, Tyska MJ (2016) Dev Cell 36:190-2002016
Accurate Prediction of Contact Numbers for Multi-Spanning Helical Membrane Proteins. Li B, Mendenhall J, Nguyen ED, Weiner BE, Fischer AW, Meiler J (2016) J Chem Inf Model 56:423-342016
Effects of Recombinant Human Bone Morphogenetic Protein-2 Dose and Ceramic Composition on New Bone Formation and Space Maintenance in a Canine Mandibular Ridge Saddle Defect Model. Talley AD, Kalpakci KN, Shimko DA, Zienkiewicz KJ, Cochran DL, Guelcher SA (2016) Tissue Eng Part A 22:469-792016
Protonation-dependent conformational dynamics of the multidrug transporter EmrE. Dastvan R, Fischer AW, Mishra S, Meiler J, Mchaourab HS (2016) Proc Natl Acad Sci U S A 113:1220-52016
Serum Metabolite Profiles Are Altered by Erlotinib Treatment and the Integrin α1-Null Genotype but Not by Post-Traumatic Osteoarthritis. Mickiewicz B, Shin SY, Pozzi A, Vogel HJ, Clark AL (2016) J Proteome Res 15:815-252016
NO clue to pathogenesis of aristolochic acid nephropathy. Gewin L (2016) Exp Physiol 101:332016
p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment. Saxon JA, Cheng DS, Han W, Polosukhin VV, McLoed AG, Richmond BW, Gleaves LA, Tanjore H, Sherrill TP, Barham W, Yull FE, Blackwell TS (2016) J Immunol 196:1891-92016
Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs. Zaynagetdinov R, Sherrill TP, Gleaves LA, Hunt P, Han W, McLoed AG, Saxon JA, Tanjore H, Gulleman PM, Young LR, Blackwell TS (2016) Oncotarget 7:5470-822016
Deleting the TGF-β receptor in proximal tubules impairs HGF signaling. Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L (2016) Am J Physiol Renal Physiol 310:F499-5102016
Characterization of the Domain Orientations of E. coli 5'-Nucleotidase by Fitting an Ensemble of Conformers to DEER Distance Distributions. Krug U, Alexander NS, Stein RA, Keim A, Mchaourab HS, Sträter N, Meiler J (2016) Structure 24:43-562016
Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign. Sliwoski G, Mendenhall J, Meiler J (2016) J Comput Aided Mol Des 30:209-172016
A Phenome-Wide Association Study Identifies a Novel Asthma Risk Locus Near TERC. Claar DD, Larkin EK, Bastarache L, Blackwell TS, Loyd JE, Hartert TV, Denny JC, Kropski JA (2016) Am J Respir Crit Care Med 193:98-1002016
Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients. Choma DP, Vanacore R, Naylor H, Zimmerman IA, Pavlichenko A, Pavlichenko A, Foye L, Carbone DP, Harris RC, Dikov MM, Tchekneva EE (2016) Am J Physiol Renal Physiol 310:F416-252016
Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment. Vilgelm AE, Johnson CA, Prasad N, Yang J, Chen SC, Ayers GD, Pawlikowski JS, Raman D, Sosman JA, Kelley M, Ecsedy JA, Shyr Y, Levy SE, Richmond A (2016) J Natl Cancer Inst 108:djv4062016
A fully automated Drosophila olfactory classical conditioning and testing system for behavioral learning and memory assessment. Jiang H, Hanna E, Gatto CL, Page TL, Bhuva B, Broadie K (2016) J Neurosci Methods 261:62-742016
Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis. Bryant AJ, Robinson LJ, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, McClellan LJ, Polosukhin VV, Tanjore H, McConaha ME, Gleaves LA, Talati MA, Hemnes AR, Fessel JP, Lawson WE, Blackwell TS, West JD (2015) Pulm Circ 5:681-902015
Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension. Wu J, Montaniel KR, Saleh MA, Xiao L, Chen W, Owens GK, Humphrey JD, Majesky MW, Paik DT, Hatzopoulos AK, Madhur MS, Harrison DG (2016) Hypertension 67:461-82016
KIM-1/TIM-1 in proximal tubular cell immune response. Brooks CR, Bonventre JV (2015) Oncotarget 6:44059-602015
Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma. Hover LD, Owens P, Munden AL, Wang J, Chambless LB, Hopkins CR, Hong CC, Moses HL, Abel TW (2016) Neuro Oncol 18:928-382016
Personalizing Therapy in Idiopathic Pulmonary Fibrosis: A Glimpse of the Future? Kropski JA, Lawson WE, Blackwell TS (2015) Am J Respir Crit Care Med 192:1409-112015
MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer. Edmonds MD, Boyd KL, Moyo T, Mitra R, Duszynski R, Arrate MP, Chen X, Zhao Z, Blackwell TS, Andl T, Eischen CM (2016) J Clin Invest 126:349-642016
Bone Marrow-derived Cells Contribute to the Pathogenesis of Pulmonary Arterial Hypertension. Yan L, Chen X, Talati M, Nunley BW, Gladson S, Blackwell T, Cogan J, Austin E, Wheeler F, Loyd J, West J, Hamid R (2016) Am J Respir Crit Care Med 193:898-9092016
Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension. Bryant AJ, Carrick RP, McConaha ME, Jones BR, Shay SD, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, Tanjore H, Hemnes AR, Karwandyar AK, Polosukhin VV, Talati MA, Dong HJ, Gleaves LA, Carrier EJ, Gaskill C, Scott EW, Majka SM, Fessel JP, Haase VH, West JD, Blackwell TS, Lawson WE (2016) Am J Physiol Lung Cell Mol Physiol 310:L249-622016
Vinculin controls talin engagement with the actomyosin machinery. Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C (2015) Nat Commun 6:100382015
Cell Receptor-Basement Membrane Interactions in Health and Disease: A Kidney-Centric View. Borza CM, Chen X, Zent R, Pozzi A (2015) Curr Top Membr 76:231-532015
Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis. Dear ML, Dani N, Parkinson W, Zhou S, Broadie K (2016) Development 143:75-872016
Comprehensive Characterization of Glycosylation and Hydroxylation of Basement Membrane Collagen IV by High-Resolution Mass Spectrometry. Basak T, Vega-Montoto L, Zimmerman LJ, Tabb DL, Hudson BG, Vanacore RM (2016) J Proteome Res 15:245-582016
p120-catenin controls contractility along the vertical axis of epithelial lateral membranes. Yu HH, Dohn MR, Markham NO, Coffey RJ, Reynolds AB (2016) J Cell Sci 129:80-942016
A Structural Study of CESA1 Catalytic Domain of Arabidopsis Cellulose Synthesis Complex: Evidence for CESA Trimers. Vandavasi VG, Putnam DK, Zhang Q, Petridis L, Heller WT, Nixon BT, Haigler CH, Kalluri U, Coates L, Langan P, Smith JC, Meiler J, O'Neill H (2016) Plant Physiol 170:123-352016
Regulation of invadopodia by mechanical signaling. Parekh A, Weaver AM (2016) Exp Cell Res 343:89-952016
Patients with ClearCode34-identified molecular subtypes of clear cell renal cell carcinoma represent unique populations with distinct comorbidities. Haake SM, Brooks SA, Welsh E, Fulp WJ, Chen DT, Dhillon J, Haura E, Sexton W, Spiess PE, Pow-Sang J, Rathmell WK, Fishman M (2016) Urol Oncol 34:122.e1-72016
Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities. Khan IS, Odom M, Ehtesham M, Colvin D, Quarles CC, McLaughlin B, Singer RJ (2016) J Neurosurg 125:152-92016
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Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia. Polosukhin VV, Lawson WE, Milstone AP, Egunova SM, Kulipanov AG, Tchuvakin SG, Massion PP, Blackwell TS (2007) Virchows Arch 451:793-8032007
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